Assistant Professor, Dermatology
School of Medicine

- UC Berkeley Regents’ and Chancellor’s Scholarship; 9/2005-5/2009
- College of Letters and Science Dean’s List; 9/2005-5/2009
- Department of Molecular and Cell Biology Outstanding Scholar Award; 5/2009
- Phi Beta Kappa; 5/2009
- NIAID Postbaccalaureate Intramural Research Award; Mentor: Ashish Jain, MD; 9/2009-7/2011
- Medical Dermatology Society Mentorship Award, Mentor: Youn Kim, MD; 10/2023
- UC Irvine Dermatology Resident Teacher of the Year; 6/2024

1. FAN X, Hussien R, Brooks GA. H2O2-induced mitochondrial fragmentation in C2C12
myocytes. Free Radic Biol Med. 2010 Dec 1;49(11):1646-54.
2. Jain A, Kovacs JA, Nelson DL, Migueles SA, Pittaluga S, Fanslow W, FAN X, Wong DW,
Massey J, Hornung R, Brown MR, Spinner JJ, Liu S, Davey V, Hill HA, Ochs H, Fleisher TA.
Partial immune reconstitution of X-linked hyper IgM syndrome with recombinant CD40
ligand. Blood. 2011 Oct 6;118(14):3811-7.
3. FAN X, Upadhyaya B, Wu L, Koh C, Santín-Durán M, Pittaluga S, Uzel G, Kleiner D,
Williams E, Ma CA, Bodansky A, Oliveira JB, Edmonds P, Hornung R, Wong DW, Fayer R,
Fleisher T, Heller T, Prussin C, Jain A. CD40 agonist antibody mediated improvement of
chronic Cryptosporidium infection in patients with X-linked hyper IgM syndrome. Clin
Immunol. 2012 May;143(2):152-61.
4. Wang HY, Ma CA, Zhao Y, FAN X, Zhou Q, Edmonds P, Uzel G, Oliveira JB, Orange J, Jain
A. Antibody deficiency associated with an inherited autosomal dominant mutation in
TWEAK. Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):5127-32.
5. Arpaia N, Campbell C, FAN X, Dikiy S, van der Veeken J, deRoos P, Liu H, Cross JR,
Pfeffer K, Coffer PJ, Rudensky AY. Metabolites produced by commensal bacteria promote
peripheral regulatory T-cell generation. Nature. 2013 Dec 19;504(7480):451-5.
6. Gasteiger G*, FAN X*, Dikiy S, Lee SY, Rudensky AY. Tissue residency of innate lymphoid
cells in lymphoid and nonlymphoid organs. Science. 2015 Nov 20;350(6263):981-5. (*Cofirst
author)
7. Stamatiades EG, Tremblay ME, Bohm M, Crozet L, Bisht K, Kao D, Coelho C, FAN X,
Yewdell WT, Davidson A, Heeger PS, Diebold S, Nimmerjahn F, Geissmann F. Immune
Monitoring of Trans-endothelial Transport by Kidney-Resident Macrophages. Cell. 2016 Aug
11;166(4):991-1003.
8. O'Sullivan TE, Rapp M, FAN X, Weizman OE, Bhardwaj P, Adams NM, Walzer T,
Dannenberg AJ, Sun JC. Adipose-Resident Group 1 Innate Lymphoid Cells Promote
Obesity-Associated Insulin Resistance. Immunity. 2016 Aug 16;45(2):428-41.
9. Chinen T, Kannan AK, Levine AG, FAN X, Klein U, Zheng Y, Gasteiger G, Feng Y, Fontenot
JD, Rudensky AY. An essential role for the IL-2 receptor in Treg cell function. Nat Immunol.
2016 Nov;17(11):1322-1333.
10. Adams NM, Lau CM, FAN X, Rapp M, Geary CD, Weizman OE, Diaz-Salazar C, Sun JC.
Transcription Factor IRF8 Orchestrates the Adaptive Natural Killer Cell Response. Immunity.
2018 Jun 19;48(6):1172-1182.e6.
11. FAN X, Moltedo B, Mendoza A, Davydov AN, Faire MB, Mazutis L, Sharma R, Pe'er D,
Chudakov DM, Rudensky AY. CD49b defines functionally mature Treg cells that survey skin
and vascular tissues. J Exp Med. 2018 Nov 5;215(11):2796-2814.
12. Zeis P*, Lian M*, FAN X*, Herman JS, Hernandez DC, Gentek R, Elias S, Symowski C,
Knöpper K, Peltokangas N, Friedrich C, Doucet-Ladeveze R, Kabat AM, Locksley RM,
Voehringer D, Bajenoff M, Rudensky AY, Romagnani C, Grün D, Gasteiger G. In Situ
Maturation and Tissue Adaptation of Type 2 Innate Lymphoid Cell Progenitors. Immunity.
2020 Oct 13;53(4):775-792. (*Co-first author)
13. Seiger K, Driscoll B, Messele F, Golbari N, FAN X, Holmes J, Zachary C. Use of Optical
Coherence Tomography to Assess Properties of Cutaneous Defects Following
Radiofrequency Microneedling and Laser Treatment. Lasers in Surgery and Medicine. 2024,
in press.

Reviews
14. FAN X, Rudensky AY. Hallmarks of Tissue-Resident Lymphocytes. Cell. 2016 Mar
10;164(6):1198-211.

Case Reports
15. Kincaid CM, Phong C, Arnold JD, FAN X, Lee BA, Mesinkovska NA. Primary cutaneous
lymphoma in a patient with mastocytosis: Is there an association? JAAD Case Rep. 2023
Apr 7;36:70-72.

F30 Individual Predoctoral NRSA Fellowship (F30AI122721). Mentor: Alexander Rudensky, PhD. Funding: $172,441. 1/2016-3/2019.

Orange County Dermatological Society

Medical Dermatology Society

Oncodermatology Society

Society for Dermatology Hospitalists

Fellow, American Academy of Dermatology

United States Cutaneous Lymphoma Consortium

Link to this profile
https://faculty.uci.edu/profile/?facultyId=7286

Last updated
11/18/2024