Harinder Singh

Picture of Harinder Singh
Assistant Adjunct Professor, Physiology & Biophysics
School of Medicine
Co-Director, Workforce Development, Institute for Clinical and Translational Science
Assistant Adjunct Professor
School of Pharmacy & Pharmaceutical Sciences
Associate Director, Graduate & Postdoctoral Success, Physiology & Biophysics
School of Medicine
Medical Student Research Program (MSRP), Institute for Clinical and Translational Science
School of Medicine
Ph.D., Temple University School of Medicine, 2014, Vascular Biology, Caveolae, NADPH Oxidase, eNOS
Phone: 210-621-3931
Email: harinder.singh@uci.edu
University of California, Irvine
Medical Science, D351
Mail Code: 1450
Irvine, CA 92697
Research Interests
Medical Physiology Instruction, STEM Workforce Development, Career & Professional Development of biomedical trainees
Postdoctoral Fellowship (2014 - 2018) at University of Illinois at Chicago (UIC): Major depressive disorder, Lipid-rafts/Caveolae, G-proteins, blood-based biomarkers for depression, antidepressant efficacy, microtubule modifying drugs as novel antidepressants, long-term antidepressant effects on cardiovascular pathophysiology.
Research Abstract
Harinder Singh, Ph.D. is a lecturer focused on medical education. He serves as the Medical Physiology and Medical Immunology course coordinator for first-year medical students. Medical Physiology teaches the underlying mechanisms of life, setting the stage for understanding pathology and pharmacology that will be used in the diagnosis and treatment of disease.

Dr. Singh also serves as the Co-Director of Workforce Development division of Institute for Clinical and Translational Sciences (ICTS) at UCI, where he helps building programs for engaging medical students into the translational research.

Previously, he served as the program director of an innovative career and professional development program for STEM PhDs & Postdocs (GPS-STEM) in helping them transition to satisfying careers, in academia and beyond. As the leader of this program, he offered innovative solutions that broaden research training, foster relationships between academia & private sector and raise awareness on how academic discoveries advance society.

In 2016, he was appointed to the Board of Directors of science advocacy organization, Future of Research, with a mission to engage & empower early career scientists with evidence-based resources in improving the scientific research endeavor.
Awards and Honors
1. In 2022, Dr. Singh was awarded the NSF funded Advancing Research Impact in Society (ARIS) fellowship for "Developing the next generation taskforce through science policy as a bridge between science and society"
2. Postdoctoral Research Grant – American Heart Association (2015-2017). Antidepressants & Cardiovascular Diseases.
3. Research award, Psychiatry Research Extravaganza, University of Illinois Chicago, 2017.
4. Research award, Chicago Chapter Society for Neuroscience, 2017.
5. Travel award, Frank Baldino award, Temple University School of Medicine, 2010
6. Research achievement award, Temple University School of Medicine, 2012.
7. Academic excellence award, University of Delhi, 1998
8. Science meritorious award, University of Delhi, 1996
Short Biography
After receiving doctorate from Temple University School of Medicine, Philadelphia (2014) and Dr. Singh conducted Postdoctoral training in Neurosciences (G-proteins in Major Depressive Disorder) at University of Illinois at Chicago (UIC) (2014-2018). Dr. Singh's postdoctoral work was funded by Americal Hearth Association (AHA) Postdoctoral fellowship (2016-2018).
Higher Education Publications -

1. Harinder Singh, David Fruman, 2019. Keys to Implementation of a Professional Development Program: Insights from UC Irvine’s GPS-BIOMED. Implementing Career Development Activities for Biomedical Trainees (Book Chapter).

2. Patrick D. Brandt; Susi Sturzenegger Varvayanis; Tracey Baas; Amanda F. Bolgioni; Janet Alder; Kimberly A. Petrie; Isabel Dominguez; Abigail M. Brown; C. Abigail Stayart; Harinder Singh. Measuring effects of trainee professional development on research productivity: A cross-institutional meta-analysis. PLOS One Biology. 2019.

3. Harinder Singh, A Bankston, G McDowell. 2020. Training Transitions: Research Dependence to Independence. OSF Preprints

4. S. Davis, Harinder Singh, JP Ruiz. 2020. Research Culture: Actionable Recommendations from Trainees to Improve Scientific Training. eLife

5. Christian Jorgensen, Miro Alexander Astore, Fátima Sancheznieto, Sridhar Vedachalam, Amreen Mughal, Maiko Le Lay, Adriana Bankston, Harinder Singh. Tracking Policy Implications and Impacts of the COVID-19 Pandemic and Related Executive Actions on a Sampling of Foreign-born Early Career Researchers in the U.S.2022. Open Science Forum Preprint

Scientific Publications -

1. Z Bertels, Harinder Singh, M. Rasenick, A Pradhan. Neuronal complexity is attenuated in preclinical models of migraine and restored by HDAC6 inhibition. eLife2021

2. Harinder Singh, M Rasenick. Membrane localized tubulin shows decreased a-tubulin acetylation in postmortem brain tissue from depressed suicides: Cytoskeletal dynamics and depression. Journal of Neuroscience, 2020

3. Tuba Sural-Fehr, Harinder Singh, L Cantuti-Castelvetri, H Zhu, M Minshall, MM Rasenick, ER Bongarzone. Psychosine causes cellular toxicity by downregulating the PI3K/Akt pathway in motor neurons. Disease Model Mechanisms, 2019

4. S Majumdar, JC Rinaldi, NR. Malhotra, T Gauntner, Harinder Singh, L Xie, W-Y Hu, S Kasper, Gail S. Prins: Differential Actions of Estrogen Receptor a and ß via Non-Genomic Signaling in Human Prostate Stem-Progenitor Cells. Endocrinology. 2019

5. Nathan Wray, Jeffrey Schappi, Harinder Singh, Mark Rasenick. NMDA receptor independent and cAMP dependent rapid antidepressant effects of Ketamine. Molecular Psychiatry, 2018

6. Harinder Singh, N Wray, J Schappi, M Rasenick. HDAC6 inhibitors show cellular antidepressant signature by translocating Gas as out of lipid-rafts. Neuropsychopharmacology, 2018

7. Woitek F, Zentilin L, Hoffman NE, Powers JC, Ottiger I, Parikh S, Kulczycki AM, Hurst M, Ring N, Wang T, Shaikh F, Gross P, Harinder Singh, Kolpakov MA, Linke A, Houser SR, Rizzo V, Sabri A, Madesh M, Giacca M, Recchia FA. Intracoronary Cytoprotective Gene Therapy: A Study of VEGF-B167 in a Pre-Clinical Animal Model of Dilated Cardiomyopathy. J Am College of Cardiology, 2015

8. Gabunia K, Ellison SP, Harinder Singh, Datta P, Kelemen SE, Rizzo V, Autieri MV. Interleukin-19 (IL-19) induces HO-1 expression and decreases reactive oxygen species in human vascular smooth muscle cells. J Biol Chem. 2012

9. Harinder Singh, Schulze DR, McMahon LR. Tolerance and cross-tolerance to cannabinoids in mice: schedule-controlled responding and hypothermia. Psychopharmacology (Berl). 2011
American Heart Association, Pre-doctoral Fellowship 2016
Union of Concerned Scientists Public Good Fund 2021
Research! America. Data Science & Art in Science 2021
National Science Policy Network (NSPN)
Advancing Research Impact in Society (ARIS) Fellow 2021
Research Centers
Institute of Clinical & Translational Sciences (ICTS)
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