Christopher James Halbrook

Picture of Christopher James Halbrook
Assistant Professor, Molecular Biology and Biochemistry
School of Biological Sciences
Ph.D., Stony Brook University, 2015, Chemical Biology
B.S., University of Wisconsin: Milwaukee, 2008, Chemistry
University of California, Irvine
134 Sprague Hall
Irvine, CA 92697
Research Interests
Pancreatic Cancer, Cancer Metabolism, Metaplasia, Pancreatitis, Organ Regeneration
Postdoctoral Training: University of Michigan 2015-2020
Research Abstract
My research combines animal models and primary cell cultures with advanced techniques in mass spectrometry-based metabolomics to explore crosstalk interactions among cell populations found in pancreatic diseases. Using these techniques, my research has led to seminal findings describing different mechanisms of metabolic crosstalk with functional consequences on tumor growth, chemoresistance, and immune suppression. The goals of our current research aim to define interactions that shape the tumor niche and contribute to immune suppression, investigate the role of metabolism in supporting cancer cell growth and therapy resistance, and determine links between cellular plasticity and inflammation responsible for driving chronic pancreatic disease and tissue regeneration.
Awards and Honors
V Scholar Award
K99/R00 NIH Pathway to Independence Award (NCI)
F32 Ruth L. Kirschstein Postdoctoral Individual National Research Service Award (NCI)
Graduate Programs
Cellular and Molecular Biosciences
Research Centers
UCI Cancer Research Institute
UCI Institute for Immunology
Chao Family Comprehensive Cancer Center
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