Jing Yang

Picture of Jing Yang
Associate Adjunct Professor, Ophthalmology
School of Medicine
M.D., Norman Bethune Health Science Center of Jilin University, China, 2000, Medicine/Ophthalmology
Ph.D., Peking University, China, 2006, Ophthalmology
Phone: (949) 824-6184
Email: jyang22@uci.edu
University of California, Irvine
845 Health Sciences Road, Room 2008
Mail Code: 1705
Irvine, CA 92697
Research Interests
stem cell therapy, retinal regeneration
1. Yu J, Azzam D, Chwa M, Schneider K, Cho J, Hsiang C, Klassen H, Kenney MC, Yang J.Age-related Macular Degeneration (AMD) Transmitochondrial Cybrids Protected from Cellular Damage and Death by Human Retinal Progenitor Cells (hRPCs). Stem Cells International. 2021 Article ID 6655372.
2. Yang, J., Menges, S., Gu, P., Tongbai, R., Samuel, M., Prather, R., Klassen, H. Porcine neural progenitor cells derived from tissue at different gestational ages can be distinguished by global transcriptome. Cell Transplantation. 2017 Sep; 26(9):1582-1595.
3. Cooper AE, Cho J, Menges S, Massods S, Xie J, Yang J, Klassen H. Immunosuppressive treatment can alter visual performance in the RCS rat. Journal of Ocular Pharmacology and Therapeutics. 2016 Jun;32(5):296-303. *Co-corresponding author
4. Qin Z, Yang J, Klassen H, Aswad DW. Isoaspartyl protein damage and repair in mouse retina. Invest Ophthalmol Vis Sci. 2014 Mar 13;55(3):1572-9.
5. Jing Yang, Ping Gu, Steven Megens, Henry Klassen. Quantitative changes in gene transcription during induction of differentiation in porcine neural progenitor cells. Mol Vis. 2012;18:1484-504.
6. Jing Yang, Jinmei Wang, Ping Gu, X. Joann You, and Henry J. Klassen. Feline neural progenitor cells I: Long-term expansion of under defined culture conditions. Stem Cells Int. 2012;2012:108340.
7. X. Joann You, Jing Yang, Ping Gu, Chee Gee Liew, and Henry J. Klassen. Feline neural progenitor cells II: Use of novel plasmid vector and hybrid promoter to drive expression of Glial Cell Line-Derived Neurotrophic Factor transgene. Stem Cells Int. 2012;2012:604982. *Co-first author.
8. Chee Gee Liew, Laughing Bear Torrez, Yukie Perez, Nicole Isolde zur Nieden, Jing Yang, Henry J. Klassen. Derivation of neural progenitors and retinal pigment epithelium from common marmoset and human pluripotent stem cells. Stem Cells Int. 2012;2012:417865.
9. X.Joann You, Ping Gu, Jinmei Wang, Tianran Song, Jing Yang, Chee Gee Liew, Henry Klassen. Efficient Transduction of Feline Neural Progenitor Cells for Delivery of Glial Cell Line-Derived Neurotrophic Factor Using a Feline Immunodeficiency Virus-Based Lentiviral Construct. Journal of Ophthalmology, 2011, pii: 378965.
10. Wang J, Yang J, Gu P, Klassen H. Effects of glial cell line-derived neurotrophic factor on cultured murine retinal progenitor cells. Molecular Vision 2010 Dec 31; 16: 2850-66.
11. Cho SJ, Lee YS, Lee JI, Bang JI, Yang J, Klassen H, Kong IK. Confirmation of Germ-Line Transmission in the Red Fluorescence Protein (RFP) transgenic Cloned Male Cat. Cell Reprogram; 2010 Dec; 12 (6): 739-47.
12. Ping Gu, Jing Yang, Jinmei Wang, Henry Klassen. Sequential changes in the gene expression profile of murine retinal progenitor cells during the induction of differentiation. Molecular Vision 2009 Oct 20; 15: 2111-22. *Co-first author.
13. Redenti S, Neeley WL, Rampani S, Saigal S, Yang J, Klassen H, Langer R, Young MJ. Engineering retinal progenitor cell and scrollable poly(glycerol-sebacate) composites for expansion and subretinal transplantation. Biomaterials 2009; 30(20): 3405-14.
14. Jing Yang, Henry Klassen, Mette Pries, Wei Wang, Mogens Holst Nissen. Vitreous humor and albumin augment the proliferation of cultured retinal precursor cells. Journal of Neuroscience Research 2009; 87(2): 495-502. *Corresponding author
15. Xiaoyong Chen, Jing Yang, Chun Zhang, Wei Wang. The randomly sampling survey of glaucoma awareness in general clinic. Chinese Ophthalmic Research 2009; 27(5): 425-428.
16. Stephen Redenti, Sarah Tao, Jing Yang, Ping Gu, Henry Klassen, Sunita Saigal, Tejal Desai and Michael J. Young. Retinal tissue engineering using mouse retinal progenitor cells and a novel biodegradable, thin-film poly(e-caprolactone) nanowire scaffold. Journal of Ocular Biology, Diseases, and Informatics 2008; 1:19-29.
17. Jing Yang, Henry Klassen, Mette Pries, Wei Wang, Mogens Holst Nissen. Aqueous humor enhances the proliferation of rat retinal precursor cells in culture and this effect is partially reproduced by ascorbic acid. Stem Cells 2006; 24: 2766-2775. *Corresponding author
18. Jing Yang, Mogens Holst Nissen, Wei Wang. Isolation, culture and identification of rat retinal progenitor cells in vitro. Zhonghua Yanke Zazhi 2006; 42 (2): 104-110. *Corresponding author
19. Jing Yang, Chun Zhang, Wei Wang . The application of amniotic membrane in glaucoma surgery. Zhongguo Shiyongyanke 2003; 12:169-172.
Professional Societies
The Association for Research in Vision and Ophthalmology
International Society for Cellular Therapy
The American Society of Retina Specialists
Drug Information Association
Research Centers
University of California, Irvine
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