Nicolas M Phielipp

Picture of Nicolas M Phielipp
Associate Professor, Neurology
School of Medicine
Phone: (949) 824-0190
University of California, Irvine

Irvine, CA 92697
Research Interests
Parkinson's, dystonia, TMS, torticollis, musician's dystonia, writer's cramp, chorea, myoclonus, tremor
Short Biography
Born and raised in Northern Patagonia Argentina. Trained in the field of Neurology, Parkinson's and Movement Disorders and Physiology of Movement at Universidad de Buenos Aires and University of Toronto, under the mentorship of Professors O Gershanik, R. Chen and A. Lang. Arrived to UCI in 2014 with mainly clinical responsibilities and working to establish a program on deep phenotyping of movement disorders.
Journal Articles

1. Effect of Ezogabine on Cortical and Spinal Motor Neuron Excitability in Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial. Wainger BJ, Macklin EA, Vucic S, McIlduff CE, Paganoni S, Maragakis NJ, Bedlack R, Goyal NA, Rutkove SB, Lange DJ, Rivner MH, Goutman SA, Ladha SS, Mauricio EA, Baloh RH, Simmons Z, Pothier L, Kassis SB, La T, Hall M, Evora A, Klements D, Hurtado A, Pereira JD, Koh J, Celnik PA, Chaudhry V, Gable K, Juel VC, Phielipp N, Marei A, Rosenquist P, Meehan S, Oskarsson B, Lewis RA, Kaur D, Kiskinis E, Woolf CJ, Eggan K, Weiss MD, Berry JD, David WS, Davila-Perez P, Camprodon JA, Pascual-Leone A, Kiernan MC, Shefner JM, Atassi N, Cudkowicz ME.JAMA Neurol. 2020 Nov 23:e204300. doi: 10.1001/jamaneurol.2020.4300. Online ahead of print.PMID: 33226425.
2. Cochran K, Hasso A, Phielipp N. Intracranial Hypotension with Mild Parkinsonism and bulbar dysfunction. Neurology: Clinical Practice Month 2019 vol. 00 no. 00 1-3 doi:10.CPJ.0000000000000777.

3. Paff M, Wang AS, Phielipp N, Vadera S, Morenkova A, Hermanowicz N, Hsu FPK. “Two-year clinical outcomes associated with robotic-assisted subthalamic lead implantation in patients with Parkinson's disease”. J Robot Surg. 2019 Sep 13. [Epub ahead of print]. PMID: 31520275.

4. Bower M, Farag M, Phielipp N. “Superficial Siderosis and Dural Ectasia in a Patient with Marfan Syndrome”. Clin Neuroradiol. 2018 Dec; 28(4):605-607. PMID: 29468260.

5. Ni Z, Kim SJ, Phielipp N, Ghosh S, Udupa K, Gunraj CA, Saha U, Hodaie M, Kalia SK, Lozano AM, Lee DJ, Moro E, Fasano A, Hallett M, Lang AE, Chen R. “Pallidal deep brain stimulation modulates cortical excitability and plasticity”. Ann Neurol. 2018 Feb; 83(2):352-362. PMID: 29369401.

6. Phielipp NM, Saha U, Sankar T, Yugeta A, Chen. “Safety of repetitive transcranial magnetic stimulation in patients with implanted cortical electrodes. An ex-vivo study and report of a case”. Clin Neurophysiol. 2017 Jun; 128(6):1109-1115. PMID: 28259678.

7. Vadera S, Chan A, Lo T, Gill A, Morenkova A, Phielipp NM, Hermanowicz N, Hsu FP. “Frameless Stereotactic Robot-Assisted Subthalamic Nucleus Deep Brain Stimulation: Case Report”. World Neurosurg. 2017 Jan; 97:762. PMID: 26585721.

8. Coulthart MB, Geschwind MD, Qureshi S, Phielipp N, Demarsh A, Abrams JY, Belay E, Gambetti P, Jansen GH, Lang AE, Schonberger LB. “A case cluster of variant Creutzfeldt-Jakob disease linked to the Kingdom of Saudi Arabia”. Brain. 2016 Oct; 139 (Pt 10):2609-2616. PMID: 27671029.

9. Mestre TA, Beaulieu-Boire I, Aquino CC, Phielipp N, Poon YY, Lui JP, So J, Fox SH. “What is a clinically important change in the Unified Dyskinesia Rating Scale in Parkinson's disease?”. . Parkinsonism Relat Disord. 2015 Nov; 21(11):1349-54. PMID: 26439944.

10. Elahi B, Phielipp N, Chen R. “N-Methyl-D-Aspartate antagonists in levodopa induced dyskinesia: a meta-analysis”. Can J Neurol Sci. 2012 Jul; 39(4):465-72. PMID: 22728853.

11. Espay AJ, Edwards MJ, Oggioni GD, Phielipp N, Cox B, Gonzalez-Usigli H, Pecina C, Heldman DA, Mishra J, Lang AE. Parkinsonism Relat Disord. “Tremor retrainment as therapeutic strategy in psychogenic (functional) tremor”. 2014 Jun; 20(6):647-50. PMID: 24679736.

12. Pondal M, Marras C, Miyasaki J, Moro E, Armstrong MJ, Strafella AP, Shah BB, Fox S, Prashanth LK, Phielipp N, Lang AE. “Clinical features of dopamine agonist withdrawal syndrome in a movement disorders clinic”. J Neurol Neurosurg Psychiatry. 2013 Feb; 84(2):130-5. PMID: 22933817.
Book Chapters

1. Phielipp Nicolas and Robert Chen. Book Title: Movement Disorders, Genetics and Models. Second Edition 2015, Chapter 10 “Neurophysiological Assessment of Movement Disorders in Humans”. Edited by Mark LeDoux. ISBN-13- 978-0124051959 ISBN-10:0124051952.

2. A Al Dakheel, Phielipp Nicolas, Janis Miyasaki. Digital Chapter: “Evidence-based advances in the treatment in the motor features of Parkinson’s Disease: What is known and what challenges remain?”.10.2217/NMT.13.32 © 2013 Future Medicine Ltd Neurodegen. Dis. Manage. (2013) 3(4), 1–11 ISSN 1758-2024 1.

4. Phielipp Nicolas and Janis Miyasaki. Digital Chapter: “Current Guidelines for the Management of Parkinson’s Disease”. Advances of Parkinson’s Disease Management. Future Medicine Ltd. January 2012, Pages 106-123. Doi: 10.2217/ebo.11.332.

5. Phielipp N., Chen R, Jankovic J. Digital Chapter: “Motor Control of Movement Disorders”. Medlink Neurology. Last version Oct 2020. Updated every two years since 2012
Professional Societies
International Parkinson's and Movement Disorders Society
American Academy of Neurology
Sociedad Neurológica Argentina
Other Experience
Clinical Fellowship Parkison's and Movement Disorders and Movement Electrophysiology
University of Toronto 2010—2013
Clinical Fellowship - Movement Disorders
Favaloro Foundation - University Hospital -Institute for Neurosciences 2009—2010
Unidad Asistencial Cesar Milstein, former French Hospital in Buenos Aires 2005—2009
Residency training- Internal Medicine
Hospital General de Agudos Teodoro Alvarez 2004—2005
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