Raquel Castellon
Assistant Researcher, Ophthalmology
School of Medicine
School of Medicine
Ph.D., Northwestern University, 1996, Tumor Cell Biology
University of California, Irvine
UCIMC, Bldg. 55, Rm. 206
Mail Code: 4380
Orange, CA 92868
UCIMC, Bldg. 55, Rm. 206
Mail Code: 4380
Orange, CA 92868
Publications
1. Involvement of protein kinase CK2 in angiogenesis and retinal neovascularization. Alexander V. Ljubimov, Sergio Caballero, Annette M. Aoki, Maria B. Grant and Raquel Castellon. (2004) Invest. Opththalmol Vis. Sci. Dec;45(12):4583-91.
2. Hamdi K. Hamdi and Raquel Castellon. (2004) A genetic variant of ACE increases cell survival: a new paradigm for biology and disease. Biochem Biophys Res Commun. 318(2004):187-191.
3. Hamdi K. Hamdi and Raquel Castellon. (2003) ACE inhibition actively promotes cell survival by regulating gene expression. Biochem Biophys Res Commun. 310(2003):1227-1235.
4. Castellon R, Mirkin BL. (2003). Effects of nerve growth factor on mitogenic growth factor responses of neuroectodermal tumor cells. J. Neuroscience Res 72:239-249.
5. Ong, J.M., Aoki A.J., Seigel, G.M., Sacerio, I., Castellon, R., Nesburn, A.B., and Kenney, M.C. (2003). Oxysterol-induced toxicity in R28 and ARPE-19 cells. Neurochemical Research. 28(6), 883-891
6. Hamdi HK, Reznik J, Castellon R, Atilano SR, Ong J, Udar N, Tavis J, Aoki A, Nesburn A, Boyer D, Ljubimov AJ, Small K, Brown DJ, Kenney MC. (2002). Alu DNA polymorphism in ACE gene is protective for age-related macular degeneration. Biochem Biophys Res Commun 295(3):668-72.
7. Castellon R, Caballero S, Tarnuzzer R, Atilano SR, Kenney MC, Grant MB, Ljubimov AV. (2002). Effects of tenascin-C on normal and diabetic retinal endothelial cells in culture. Invest. Opththalmol Vis. Sci. 43(8):2758-66.
8. Raquel Castellon, Hamdi K. Hamdi, Ingrid Sacerio, Annette M. Aoki, M. Cristina Kenney and Alexander V. Ljubimov. (2002). Effects of angiogenic growth factor combinations on retinal endothelial cells Exp Eye Res. 74(4):523-35
9. Saghizadeh M, Brown DJ, Castellon R, Chwa M, Huang GH, Ljubimova JY, Rosenberg S, Spirin KS, Stolitenko RB, Adachi W, Kinoshita S, Murphy G, Windsor LJ, Kenney MC, Ljubimov AV. (2001). Overexpression of MMP-10 and MMP-3 in human diabetic corneas: A possible mechanism of basement membrane and integrin alterations. Am. J. Pathol. 158(2):723-34.
10. Castellon R, Mirkin BL. (2000). Retroviral transfer of the beta-nerve growth factor gene into murine neuroectodermal tumor cells modulates cell proliferation rate, neurite formation, and NGF binding site expression. J. Neurosci. Res. 59:265-275.
11. Spirin KS, Ljubimov AV, Castellon R, Wiedoeft O, Marano M, Sheppard D, Kenney MC, Brown DJ. (1999). Analysis of gene expression in human bullous keratopathy corneas containing limiting amounts of RNA. Invest. Ophthalmol. Vis. Sci. 40:3108-3115.
12. Varanasi U, Chu R, Huang Q, Castellon R, Yeldandi AV, Reddy JK. (1996). Identification of a peroxisome proliferator-responsive element in the upstream region of the human peroxisomal fatty-acyl CoA oxidase gene. J. Biol. Chem., 271:2147-2155.
2. Hamdi K. Hamdi and Raquel Castellon. (2004) A genetic variant of ACE increases cell survival: a new paradigm for biology and disease. Biochem Biophys Res Commun. 318(2004):187-191.
3. Hamdi K. Hamdi and Raquel Castellon. (2003) ACE inhibition actively promotes cell survival by regulating gene expression. Biochem Biophys Res Commun. 310(2003):1227-1235.
4. Castellon R, Mirkin BL. (2003). Effects of nerve growth factor on mitogenic growth factor responses of neuroectodermal tumor cells. J. Neuroscience Res 72:239-249.
5. Ong, J.M., Aoki A.J., Seigel, G.M., Sacerio, I., Castellon, R., Nesburn, A.B., and Kenney, M.C. (2003). Oxysterol-induced toxicity in R28 and ARPE-19 cells. Neurochemical Research. 28(6), 883-891
6. Hamdi HK, Reznik J, Castellon R, Atilano SR, Ong J, Udar N, Tavis J, Aoki A, Nesburn A, Boyer D, Ljubimov AJ, Small K, Brown DJ, Kenney MC. (2002). Alu DNA polymorphism in ACE gene is protective for age-related macular degeneration. Biochem Biophys Res Commun 295(3):668-72.
7. Castellon R, Caballero S, Tarnuzzer R, Atilano SR, Kenney MC, Grant MB, Ljubimov AV. (2002). Effects of tenascin-C on normal and diabetic retinal endothelial cells in culture. Invest. Opththalmol Vis. Sci. 43(8):2758-66.
8. Raquel Castellon, Hamdi K. Hamdi, Ingrid Sacerio, Annette M. Aoki, M. Cristina Kenney and Alexander V. Ljubimov. (2002). Effects of angiogenic growth factor combinations on retinal endothelial cells Exp Eye Res. 74(4):523-35
9. Saghizadeh M, Brown DJ, Castellon R, Chwa M, Huang GH, Ljubimova JY, Rosenberg S, Spirin KS, Stolitenko RB, Adachi W, Kinoshita S, Murphy G, Windsor LJ, Kenney MC, Ljubimov AV. (2001). Overexpression of MMP-10 and MMP-3 in human diabetic corneas: A possible mechanism of basement membrane and integrin alterations. Am. J. Pathol. 158(2):723-34.
10. Castellon R, Mirkin BL. (2000). Retroviral transfer of the beta-nerve growth factor gene into murine neuroectodermal tumor cells modulates cell proliferation rate, neurite formation, and NGF binding site expression. J. Neurosci. Res. 59:265-275.
11. Spirin KS, Ljubimov AV, Castellon R, Wiedoeft O, Marano M, Sheppard D, Kenney MC, Brown DJ. (1999). Analysis of gene expression in human bullous keratopathy corneas containing limiting amounts of RNA. Invest. Ophthalmol. Vis. Sci. 40:3108-3115.
12. Varanasi U, Chu R, Huang Q, Castellon R, Yeldandi AV, Reddy JK. (1996). Identification of a peroxisome proliferator-responsive element in the upstream region of the human peroxisomal fatty-acyl CoA oxidase gene. J. Biol. Chem., 271:2147-2155.
Professional Societies
ARVO
society for neuroscience
AACR
Other Experience
Postdoctoral Fellow
NIH-NICHD-Dev. Neurobiol; Mol. Phamacol. 1996—1999
NIH-NICHD-Dev. Neurobiol; Mol. Phamacol. 1996—1999
Research Scientist
Cedars Sinai Medical Center 1999—2002
Cedars Sinai Medical Center 1999—2002
Graduate Programs
Cancer Biology
Link to this profile
https://faculty.uci.edu/profile/?facultyId=5159
https://faculty.uci.edu/profile/?facultyId=5159
Last updated
01/05/2005
01/05/2005