Toai T Nguyen

Picture of Toai T Nguyen
Specialist, Molecular Biology and Biochemistry
School of Biological Sciences
Academic Coordinator/ Instructor, Minority Science Programs
School of Biological Sciences
Ph.D., UNIVERSITY OF CALIFORNIA, IRVINE, 1987, BIOLOGICAL SCIENCES
B.A., UNIVERSITY OF CALIFORNIA, SAN DIEGO, 1979, BIOLOGICAL SCIENCES
Phone: 949-824-5158
Fax: 949-824-6599
Email: ttnguyen@uci.edu
University of California, Irvine
279 Steinhaus Hall (Bldg 502)
Mail Code: 2527
Irvine, CA 92697
Research Interests
Molecular biology of gene expression; virology; proteomics; vaccine development
Academic Distinctions
1976 – 1977: Alpha Gamma Sigma Honor Society
1978 – 1979: Provost’s Honor List, Univ of Calif-San Diego
1979 – 1983: National Research Service Award
Appointments
May 87 – Aug 91: Postgraduate Researcher; Department of Ecology and Evolutionary Biology, School of Biological Sciences; Univ of Calif-Irvine

Sep 91 – Jun 94: Postgraduate Researcher; Department of Biological Chemistry College of Medicine; Univ of Calif-Irvine

Jul 94 – Jun 98: Assistant Researcher; Department of Medicine, College of Medicine; Univ of Calif-Irvine

Jul 98 – Jun 03: Associate Specialist; Department of Molecular Biology & Biochemistry; School of Biological Sciences; Univ of Calif-Irvine

Jul 03 – present: Specialist; Department of Molecular Biology & Biochemistry
School of Biological Sciences; Univ of Calif-Irvine

Oct 05 – present: Academic Coordinator/ Instructor; Minority Science Programs
School of Biological Sciences; Univ of Calif-Irvine
Publications
1. NGUYEN, T.T., K. Postle and K.P. Bertrand. Sequence homology between the tetracycline-resistance determinants of Tn10 and pBR322. Gene 25:83-92, 1983.
2. Moyed, H.S., T.T. NGUYEN and K.P. Bertrand. Multicopy Tn10 tet plasmids confer sensitivity to induction of tet gene expression. J. Bacteriol. 155:549-556, 1983.
3. Postle, K., T.T. NGUYEN and K.P. Bertrand. Nucleotide sequence of the repressor gene of the Tn10 tetracycline resistance determinant. Nucl. Acids Res. 12:4849-4863, 1984.
4. Souza V., T.T. NGUYEN, R.R. Hudson, D. Piñero D. and R.E. Lenski. Hierarchical analysis of linkage disequilibrium in Rhizobium populations: evidence for sex? Proc. Natl. Acad. Sci. U.S.A. 89:8389-93, 1992.
5. Allard J.D., M.L. Gibson, L.H. Vu , T.T. NGUYEN and K.P. Bertrand. Nucleotide sequence of class D tetracycline resistance genes from Salmonella ordonez. Mol. Gen. Genet. 237:301-305, 1993.
6. Lenski, R.E., S.C. Simpson and T.T. NGUYEN. Genetic analysis of a plasmid-encoded, host-genotype specific enhancement of bacterial fitness. J. Bacteriol. 176:3140-3147, 1994.
7. Keys, D.A., B.-S. Lee, J.A. Dodd, T.T. NGUYEN, L. Vu, E. Fantino, L.M. Burson, Y. Nogi and M. Nomura. Multiprotein transcription factor UAF interacts with the upstream element of the yeast RNA polymerase I promoter and forms a stable preinitiation complex. Genes and Dev. 10:887-903, 1996.
8. Said, H.M., T.T. NGUYEN, D.L. Dyer, K.H. Cowan, and S.A. Rubin. Intestinal transport of folate: Identification of a mouse intestinal cDNA and localization of its mRNA. Biochim. Biophys. Acta, 1281:164-172, 1996.
9. NGUYEN, T.T., D.L. Dyer, D.D. Dunning, S.A. Rubin, K.E. Grant, and H.M. Said. 1997. Human intestinal folate transport: cloning, expression, and distribution of complementary RNA. Gastroenterol., 112:783-791.
10. Kumar C.K., T.T. NGUYEN, F.B. Gonzales, H.M. Said. 1998. Comparison of intestinal folate carrier clone expressed in IEC-6 and in Xenopus oocytes. Am J Physiol., 274:C289-94
11. NGUYEN, TT, J.P. Nery, S. Joseph, C.E. Rocha, G.E. Carney, K.R. Spindler, and L.P. Villarreal. 1999. Mouse adenovirus (MAV-1) expression in primary human endothelial cells and generation of a full-length infectious plasmid. Gene Therapy, 6:1291-1297
12. Davies, D. H., Liang, X., Hernandez, J. E., Randall, A., Hirst, S., Mu, Y., Romero, K. M., NGUYEN, T. T., Kalantari-Dehaghi, M., Crotty, S., Baldi, P., Villarreal, L. P. and Felgner, P. L. Profiling the humoral immune response to infection by using proteome microarrays: High-throughput vaccine and diagnostic antigen discovery. Proc.Natl.Acad.Sci.U.S.A. 102, 547-552, 2005.
Grants
1. Human small intestinal folate uptake: Molecular identification and characterization of the gene Long Beach Memorial Medical Center Grant. Kenneth E. Grant, M.D. (Principal investigator), Hamid M. Said, Ph.D., Pharm.D., Toai T. Nguyen, Ph.D., Eric McCloud, M.D., and Syed Hamid, M.D. (Co-investigators). Memorial Medical Center Foundation, Long Beach, California, 8/95 – 7/96
2. Intestinal folate uptake: Physiology and molecular aspects. Department of Veterans Affairs Merit Review Grant. Hamid Said, Ph.D., Pharm.D. (Principal investigator), Toai T. Nguyen, Ph.D. (Co-investigator). Department of Veterans Affairs, 4/96 – 3/01
Other Experience
Instructor
Minority Science Programs, UCI 1999—2005
Instructor
Virus Engineering Laboratory (Bio Sci 124L/ Mol Bio 224), UCI 2000—2005
Academic Coordinator/ Instructor
Minorty Science Programs, UCI 2005—2005
Graduate Programs
Biotechnology
Mechanisms of Gene Expression
Research Centers
Center for Virus Research, UCI
Last updated
10/18/2005