Nir Drayman

picture of Nir  Drayman

Assistant Professor, Molecular Biology and Biochemistry
School of Biological Sciences


Ph.D., The Hebrew University of Jerusalem, 2015, Virology and Cell Biology

Email: nirdra@uci.edu

University of California, Irvine
3305 McGaugh Hall
Irvine, CA 92697
Research Interests
Single-Cell Virology, Systems Biology, Machine Learning, Live-imaging, Virus-Host interactions, Antivirals, Single-Cell RNA-sequencing.
URLs
Appointments
2016 - 2022 | Postdoc | The University of Chicago | Prof. Savas Tay's lab
2015 - 2016 | Postdoc | The Weizmann Institute of Science | Prof. Uri Alon's lab
Research Abstract
Our lab is fascinated with the vast heterogeneity presented by seemingly identical cells during all stages of viral infection. Our previous work, as well as that of many others, have shown extreme cell-to-cell variability among infected cells in the the timing and level of viral gene expression and the number of progeny they produce.
We aim to uncover the molecular determinants of viral infection outcome, a fundamental question in Virology and Cell Biology, the answer to which will allow the rational design of new anti-viral therapies. The research in the lab focuses on developing new approaches to interrogate virus-host interactions at the single cell level, by combining viral genetics, single-cell RNA-sequencing, microfluidics, live-cell imaging and machine learning, using Herpes Simplex virus 1 (HSV-1) as a model system.
Publications
Other Experience
Research Center
Last updated
07/08/2022