Assistant Professor, Dermatology
School of Medicine

Director of Resident Research Education, Dermatology
School of Medicine

Vitiligo, Melanocytic nevi, Melanoma

2023 American Academy of Dermatology Skin Care For Developing Countries Grant Project Sponsor
2022 American Skin Association Calder Research Scholar Award Vitiligo/Pigment Disorders
2022 UC Irvine School of Medicine Outstanding Early-Career Faculty Research Award
2021 Vitiligo International Symposium Best Oral Presentation Award
2020 UC Irvine Institute of Clinical and Translational Science KL-2 Scholar
2019 Pan American Society for Pigment Cell Research Travel Award
2017 CalDerm Symposium Resident Symposium Presenter
2017 Society of Investigative Dermatology’s Resident Retreat
2015 Eugene Sydney Bereston Award for Excellence in Dermatology
2015 Charles L. Wisseman, Jr. Award for Excellence in Microbiology & Immunology
(University of Maryland School of Medicine)
2013 Graduate Program in Life Sciences Molecular Microbiology & Immunology program Ollie Eylar Award Winner
2011 University of Maryland GPILS Outstanding PhD Scholar Award Winner
2011 Biolegend Travel Award Recipient
2008 Medical Student Research Day Oral Presentation Winner
2008 American Gatroenterological Association Student Research Fellowship
2007 John Hopkins University Masters Scholarship

I am a Dermatology trained physician scientist interested in understanding tissue homeostatic mechanisms in melanocyte-related disorders in the skin. I was in the Medical Scientist Training Program at the University of Maryland School of Medicine where I completed my PhD training studying the gut immune response to Helicobacter pylori in Dr. Thomas Blanchard’s laboratory. I completed my Dermatology Residency training at UCI and Board Certification in July 2019. Currently, I am an assistant professor and the first fellow in the Physician Scientist Fellowship Track in the Department of Dermatology. I am a KL-2 scholar at the University of California Irvine Institute of Clinical and Translational Research with protected research time and funding.

Shiu J, Zhang L, Lentsch G, Flesher JL, Jin S, Polleys C, Jo SJ, Mizzoni C, Mobasher P, Kwan J, Rius-Diaz F, Tromberg BJ, Georgakoudi I, Nie Q, Balu M, Ganesan AK. Multimodal analyses of vitiligo skin identify tissue characteristics of stable disease. JCI Insight. 2022 Jul 8;7(13):e154585. doi: 10.1172/jci.insight.154585.

Xiao H, Shiu J, Chen CF, Wu J, Zhou P, Telang SS, Ruiz-Vega R, Edwards RA, Nie Q, Lander AD, Ganesan AK. Uncovering minimal pathways in melanoma initiation. Nat Comm 2025 Jun 26;16(1):5369.

Shiu J, Lentsch G, Polleys CM, Mobasher P, Ericson M, Georgakoudi I, Ganesan AK, Balu M. Non-invasive Imaging Techniques for Monitoring Cellular Response to Treatment in Stable Vitiligo. J Invest Dermatol. 2023 Nov 10:S0022-202X(23)02981-0. doi: 10.1016/j.jid.2023.10.006.

Shiu J, Lander AD. When Oncogenes Do Not Cause Cancer. Elife. 2021 Dec 9;10:e74912. Doi:10.7554/eLife.74912.

Sun P, Kraus CN, Zhao W, Xu J, Suh S, Nguyen Q, Jia Y, Nair A, Oakes M, Tinoco R, Shiu J, Sun B, Elsensohn A, Atwood SX, Nie Q, Dai X. Spatial and single-cell transcriptomics reveal keratinocytes as key players in vulvar lichen sclerosus pathogenesis. J Invest Dermatol. 2025 Aug 29:S0022-202X(25)02394-2. doi: 10.1016/j.jid.2025.08.022.

Choi FD, Kraus CN, Elsensohn AN, Carley SK, Lehmer LM, Nguyen RT, Linden KG, Shiu J. PD-1 and PD-L1 inhibitors in the treatment of non-melanoma skin cancer: a systematic review. J Am Acad Dermatol. 2020. Feb 82(2):440-459.

Vallmitjana A, Durkin A, Dvornikov A, Torrado B, Kelly KM, Shiu J, Ganesan AK, Balu M. Label-free multiphoton microscopy of human skin: longitudinal studies capturing cell dynamics. Biomed Opt Express. 2025 Sept 3;16(10):3912-22. Doi: 10.1364/BOE.570105.

Vuong LM, Hachey S, Shiu J, Xie DF, Salvador N, Brindani N, Bertozzi SM, Summa M, Bertorelli R, Armirotti A, Pham R, Ku VSH, Limbekar SD, Nguyen T, Choi B, Hughes CCW, De Vivo M, Ganesan AK. CDC42-effector interaction inhibitors alter patterns of vessel arborization in skin and tumors in vivo. iScience. 2025 Jul 14;28(7):112971. doi: 10.1016/j.isci.2025.112971.

Ruiz-Vega R, Chen CF, Razzak E, Vasudeva P, Krasieva TB, Shiu J, Caldwell MG, Yan H, Lowengrub J, Ganesan AK, Lander AD. Dynamics of nevus development implicate cell cooperation in the growth arrest of transformed melanocytes. Elife. 2020 Oct 13;9:e61026.

Mobasher P, Shiu J, Lentsch G, Ganesan AK. Comparing the Efficacy of 2 Different Harvesting Techniques for Melanocyte Keratinocyte Transplantation in Vitiligo. Dermatol Surg. 2021 May; 47(5):732-733.

Yale K, Roux J, Shiu J. A cross-sectional study of cutaneous immune-related adverse effects in Hispanic patients after immune checkpoint inhibitor use of cancer therapy. J Am Acad Dermatol. 2024 Sep 26:S0190-9622(24)02886-X. Doi: 10.1016/j.jaad.2024.09.030.

07/01/2020-06/30/2023 | UCI Institute for Clinical and Translational Science 5KL2TR1416-6 | Title: Elucidating the Role of Keratinocyte Metabolism in Vitiligo Persistence | Caizzo (PI), Shiu (Scholar)

3/1/2024 | Title: A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study to Evaluate the Efficacy, Safety, and Tolerability of Upadacitinib in Adult and Adolescent Subjects with Non-segmental Vitiligo Who Are Eligible for Systemic Therapy | Shiu (PI)

Skin of Color Society Career Development Award Title: Elucidating Racial Differences in Vitiligo Presentation & Treatment Response

NIAMS K08AR081406 Title: Determining how local factors influence repigmentation in stable vitiligo

American Academy of Dermatology

Women’s Dermatologic Society

Society of Investigative Dermatology

Medical Dermatologic Society

PanAmerican Society for Pigment Cell Research

Link to this profile
https://faculty.uci.edu/profile/?facultyId=6720

Last updated
10/24/2025