Ichiro Yuki

picture of Ichiro  Yuki

Associate Clinical Professor, Neurological Surgery
School of Medicine


M.D., The Jikei University School of Medicine, 1995

Phone: (714) 456-6966
Email: iyuki@hs.uci.edu

University of California, Irvine
101 The City Drive, South
Building 200, Suite 210
Mail Code: 5397
Orange, CA 92868
Research Interests
Development of neuro-endovascular devices, Development of imaging software for angiography system, Neuroimaging
Academic Distinctions
Honors and Special Awards

1) 2004 Gold prize for investigational scientific exhibit at the 20th annual meeting of the Japanese Society for Neuroendovascular therapy, Hokkaido, Japan 2004

2) 2004 Silver prize for investigational scientific exhibit at the 20th annual meeting of the Japanese Society for Neuroendovascular therapy, Hokkaido, Japan 2004

3) 2006 Outstanding Presentation Awards “Michael Brothers Memorial Award”
by 2005-2006 ASNR Education Committee at annual meeting of the American Society of Neuroradiology, San Diego, U.S.A.2006

4) 2007 Outstanding Scientific Paper Awards by JSNET (co-investigator)
The 23rd Annual Meeting of the Japanese Society for Neuroendovascular Therapy

5) 2008 Outstanding Scientific Paper Awards by JSNET
The 24rd Annual Meeting of the Japanese Society for Neuroendovascular Therapy, Nagoya, Japan 2008

6) 2009 Silver prize for investigational scientific exhibit at the 25th annual meeting of the Japanese Society for Neuroendovascular therapy, Toyama, Japan 2004
Appointments
Clinical Fellowship
Division of Interventional Radiology, UCLA

Division of Interventional Neuroradiology, UCLA
Associate Adjunct Professor, Department of Radiological Sciences, David Geffen School of Medicine at UCLA

Leo G Rigler Research Center, UCLA (Division of Interventional Neuroradiology)
Co-Director, Leo G Rigler Research Center, UCLA

The Jikei University Hospital
Associate Professor, Department of Neurosurgery, The Jikei University School of Medicine
Research Abstract
Publications

1.Yuki I, Akiyama M, Kamikubo T, Kitajima T, Sakai H
A patient of cervical disc hernia with quadriplegia caused by slight flexion movement: case report. Tokyo Medical Association Journal. 1998 March; 50(10):2055-7. (Japanese)

2. Kanda M, Yuhki I, Murakami Y, et al: Monostotic fronto-orbital fibrous dysplasia with convulsion--case report. Neurol Med Chir (Tokyo) 42:36-39, 2002

3. Yuki I, Murayama Y, Vinuela F: Endovascular management of dissecting vertebrobasilar artery aneurysms in patients presenting with acute subarachnoid hemorrhage. J Neurosurg 103:649-655, 2005.

4. Murayama Y, Vinuela F, Ishii A, Nien YL, Yuki I, Duckwiler G, Jahan R: Initial clinical experience with matrix detachable coils for the treatment of intracranial aneurysms. J Neurosurg 105:192-199, 2006.

5. Ishii A, Vinuela F, Murayama Y, Yuki I, Nien YL, Yeh DT, Vinters HV: Swine model of carotid artery atherosclerosis: experimental induction by surgical partial ligation and dietary hypercholesterolemia. AJNR Am J Neuroradiol 27:1893-1899, 2006.

6. Lee D, Yuki I, Murayama Y, Chiang A, Nishimura I, Vinters HV, Wang CJ, Nien YL, Ishil A, Wu BM, Vinuela F: Thrombus organization and healing in the swine experimental aneurysm model. Part I. A histological and molecular analysis. J Neurosurg 107:94-108, 2007.

7. Yuki I, Lee D, Murayama Y, Chiang A, Vinters HV, Nismmura I, Wang CJ, Ishii A, Wu BM, Vinuela F: Thrombus organization and healing in an experimental aneurysm model. Part II. The effect of various types of bioactive bioabsorbable polymeric coils. J Neurosurg 107:109-120, 2007.

8. Ishii A, Murayama Y, Nien YL, Yuki I, Adapon PH, Kim R, Jahan R, Duckwiler G, Viñuela F : Immediate and midterm outcomes of patients with cerebral aneurysms treated with Matrix1 and Matrix2 coils: a comparative analysis based on a single-center experience in 250 consecutive cases. Neurosurgery 2008 Dec; 63(6):1071-7

9. Takao H, Murayama Y, Yuki I, Ishibashi T, Ebara M, Irie K, Yoshioka H, Mori Y,Vinuela F, Abe T : Endovascular treatment of experimental aneurysms using a combination of thermoreversible gelation polymer and protection devices: feasibility study. Neurosurgery. 2009 Sep;65(3):601-9; discussion 609.

10. Yuki I, Kim RH, Duckwiler G, Jahan R, Tateshima S, Gonzalez N, Gorgulho A, Diaz JL, De Salles AA, Viñuela F: Treatment of brain arteriovenous malformations with high-flow arteriovenous fistulas: risk and complications associated with endovascular embolization in multimodality treatment. J Neurosurg. 2009 Oct 16. [Epub ahead of print]

11. Ebara M, Yuki I, Murayama Y, Saguchi T, Nien Y, Vinuela, Abe T: A Rabbit Model for efficacy evaluation of Endovascular Coil Materials Surg Neurol. 2009 Dec;72(6):620-7; discussion 627.

12. Kan I, Yuki I, Myrayama Y, Vinuela F.A., Kim R.H., Vinters H.V., Vinuela F : A Novel Method of Thrombus Preparation for Use in a Swine Model for Evaluation of Thrombectomy Devices AJNR Am J Neuroradiol. 2010 Jan 21.

13. Yuki I, Uchiyama N, Nien Y, Lee D, Murayama Y, Ebara M, Ishii A, Chiang A, Vinters H, Nishimura I, Wu B, Vinuela F: Intravascular Tissue Reactions Induced by Various Types of Bioabsorbable Polymeric Materials:Correlation between the Degradation Profiles and Corresponding Tissue Reactions Neuroradiology. 2010 Feb 10.

14. Yuki I, Kan I, Vinters HV, Kim RH, Golshan A, Vinuela FA, Sayre JW, Murayama Y, Vinuela F, “The Impact of Thromboemboli Histology on the Performance of a Mechanical Thrombectomy Device” AJNR Am J Neuroradiol. 2012 Apr;33(4):643-8. Epub 2011 Dec 29.

15. Yuki I, Kan I, Vinters HV, Golshan A, Sohn J, Murayama Y, Vinuela F, “A Swine Model to Analyze Arterial Structural Changes Induced by Mechanical Thrombectomy” AJNR Am J Neuroradiol. 2012 Jul 12.

16. Fujimoto M, Salamon N, Mayor F, Yuki I, Takemoto K, Vinters HV, Viñuela F. “Characterization of arterial thrombus composition by magnetic resonance imaging in a swine stroke model.” Stroke. 2013 May;44(5):1463-5.

17. Dobashi H, Akasaki Y, Yuki I, Arai T, Ohashi H, Murayama Y, Takao, Abe T “Thermoreversible Gelation Polymer (TGP) as an Embolic Material for Aneurysm Treatment: A Delivery Device for Dermal Fibroblasts and Basic Fibroblast Growing Factor into an Experimental Aneurysm in Rats” J Neurointerv Surg. 2013 Nov;5(6):586-90.

18. Kobayashi N, Murayama Y, Yuki I, Ishibashi T, Ebara M, Arakawa H, Irie K, Takao H, Kajiwara I, Nishimura K, Karagiozov K, Urashima M. “Natural Course of Dissecting Vertebrobasilar Artery Aneurysms without Stroke.” AJNR Am J Neuroradiol. 2014 Mar 7. [Epub ahead of print]

19. Yuki I, Spitzer D, Guglielmi G, Duckwiler G, Fujimoto M, Takao H, Jahan R, Tateshima S, Murayama Y, Vinuela F. “Immunohistochemical analysis of a ruptured basilar top aneurysm autopsied 22 years after embolization with Guglielmi detachable coils.” BMJ Case Rep. 2014 Jul 23;2014, England.

20. Yuki I, Kambayashi Y, Ikemura A, Abe Y, Kan I, Mohamed A, Dahmani C, Suzuki T, Ishibashi T, Takao H, Urashima M, Murayama Y. “High-Resolution C-Arm CT and Metal Artifact Reduction Software: A Novel Imaging Modality for Analyzing Aneurysms Treated with Stent-Assisted Coil Embolization.”
AJNR Am J Neuroradiol. 2015 Sep 10.

21. Komatsu T, Mitsumura H, Yuki I, Iguchi Y. “Primary Sjögren's syndrome presenting with multiple aneurysmal dilatation of cerebral arteries and causing repetitive intracranial hemorrhage”, J Neurol Sci. 2016 Jun 15;365:124-5.

22. Murayama Y, Takao H, Ishibashi T, Saguchi T, Ebara M, Yuki I, Arakawa H, Irie K, Urashima M, Molyneux AJ. “Risk Analysis of Unruptured Intracranial Aneurysms: Prospective 10-Year Cohort Study.” Stroke. 2016 Feb;47(2):365-71 Epub 2016 Jan 7.

23. Mori R, Yuki I, Kajiwara I, Nonaka Y, Ishibashi T, Karagiozov K, Dahmani C, Murayama Y. “Hybrid Operating Room for Combined Neuroendovascular and Endoscopic Treatment of Ruptured Cerebral Aneurysms with Intraventricular Hemorrhage.” World Neurosurg. 2016 May;89:727.e9-727.e12. Epub 2016 Jan 21.

24. Ishibashi T, Takao H, Suzuki T, Yuki I, Kaku S, Kan I, Nishimura K, Suzuki T, Watanabe M, Karagiozov K, Murayama Y. Tailor-made shaping of microcatheters using three-dimensional printed vessel models for endovascular coil embolization. Comput Biol Med. 2016 Oct 1;77: 59-63. doi:10.1016/j.compbiomed.2016.07.005. Epub 2016 Aug 2.

25. Kambayashi Y, Yuki I, Ishibashi T, Ikemura A, Umezawa T, Suzuki M, Kan I, Takao H, Murayama Y. “Immunohistochemical Analysis of Debris Captured by Filter-Type Distal Embolic Protection Devices for Carotid Artery Stenting” J Stroke Cerebrovasc Dis. 2017 Apr;26(4):816-822.
doi:10.1016/j.jstrokecerebrovasdis.2016.10.025. Epub 2016 Nov 17.

26. Maruyama F, Irie K, Yuki I, Takei J, Hatano K, Tanaka T, Hasegawa Y, Murayama Y. “Outcome of Coil Embolization for Subarachnoid Hemorrhage Accompanied with Intracerebral Hematoma”. No Shinkei Geka. 2017 Nov;45(11):955-963. doi: 10.11477/mf.1436203627. Japanese.

27. Misaki K, Takao H, Suzuki T, Nishimura K, Kan I, Yuki I, Ishibashi T, Yamamoto M, Murayama Y. “Estimated pretreatment hemodynamic prognostic factors of aneurysm recurrence after endovascular embolization. Technol Health Care. 2017 Oct 23;25(5):843-850. doi: 10.3233/THC-160495.

28. Kodata T, Kamata K, Fujiwara K, Kano M, Yamakawa T, Yuki I, Murayama Y. “A new infarction detection method based on heart rate variability in rat middle cerebral artery occlusion model.” Conf Proc IEEE Eng Med Biol Soc. 2017 Jul;2017:3061-3064. doi: 10.1109/EMBC.2017.8037503.

29. Yuki I, Ikemura A, Suzuki H, Suzuki T, Ishibashi T, Abe Y, Urashima M, Dahmani C, Murayama Y “Time-resolved magnetic resonance angiography (TR-MRA) for the evaluation of post coiling aneurysms; A quantitative analysis of the residual aneurysm using full-width at half-maximum (FWHM) value” PLOS one. September 7, 2018

30. Kodata T, Kamata K, Fujiwara K, Kano M, Yamakawa T, Yuki I, Murayama Y.Ischemic stroke detection by analyzing heart rate variability in rat middle cerebral artery occlusion model. IEEE Trans Neural Syst Rehabil Eng. 2018 Jun;26(6):1152-1160. doi: 10.1109/TNSRE.2018.2834554. PMID: 29877839.

31.Ikemura A, Yuki I, Suzuki H, Suzuki T, Ishibashi T, Abe Y, Urashima M, Dahmani C, Murayama Y “Time-resolved magnetic resonance angiography (TR-MRA) for the evaluation of post coiling brain aneurysms; A quantitative analysis of the residual aneurysm using full-width at half-maximum (FWHM) value” PLOS one, 2018 Sep 7;13(9):e0203615. doi: 10.1371/journal.pone.0203615. eCollection 2018. PMID: 30192859.

32.Nishimura K, Otani K, Mohamed A, Dahmani C, Ishibashi T, Yuki I, Kaku S, Takao H, Murayama Y. “Accuracy of Length of Virtual Stents in Treatment of Intracranial Wide-Necked Aneurysms” Cardiovasc Intervent Radiol. 2019 Aug;42(8):1168-1174. doi: 10.1007/s00270-019-02230-9. Epub 2019 May 10. PMID: 31076839.

33. Kato N, Yuki I, Ishibashi T, Ikemura A, Kan I, Nishimura K, Kodama T, Kaku S, Abe Y, Otani K, Murayama Y, “Visualization of stent apposition after stent-assisted coiling of intracranial aneurysms using high resolution 3D fusion images acquired by C-arm CT” Journal of Neuroendovascular Surgery (JNIS), 2019Aug12.pii:neurintsurg-2019-014966.doi:10.1136/neurintsurg-2019-014966.12August 2019.

34. Yuki I, Ishibashi T, Dahmani C, Kato N, Ikemura A, Abe Y, Otani K, Kodama T, Kan I, Nishimura K, Murayama Y. “Combination of high-resolution cone beam computed tomography and metal artefact reduction software: a new image fusion technique for evaluating intracranial stent apposition after aneurysm treatment.” BMJ(British Medical Journal) Case Rep. 2019 Sep 17;12(9). pii: e230687. doi: 10.1136/bcr-2019-230687. PMID: 31533950.

35. Ikemura A, Yuki I, Otani K, Ishibashi T, Dahmani C, Ebara M, Abe Y, Kajiwara I, Watanabe M, Murayama Y. “Evaluation of balloon test occlusion before therapeutic carotid artery occlusion: Flat detector computed tomography cerebral blood volume imaging versus single-photon emission computed tomography.” World Neurosurg. 2019 Sep 21. pii: S1878-8750(19)32507-0. doi: 10.1016/j.wneu.2019.09.077.PMID: 31550537.

36.Abe Y, Yuki I, Otani K, Shoji T, Ishibashi T, Murayama Y. “Agreement of intracranial vessel diameters measured on 2D and 3D digital subtraction angiography using an automatic windowing algorithm.” J Neuroradiol. 2019. Sep 26. pii: S0150-9861(19)30446-8. doi: 10.1016/j.neurad.2019.08.004.
Awards and Honors
UCI Beall Applied Innovation, Proof of Product (POP) Award. PI. “Development of a Liquid Embolic Material for the Treatment of Neurovascular Diseases: Preclinical Experiments and Market Evaluation with Regulatory Strategy”
Publications
Michishita S, Ishibashi T, Yuki I, Urashima M, Karagiozov K, Kodama T, Kan I, Nishimura K, Kato N, Ikemura A, Murayama Y. “Visual complications after coil embolization of internal carotid artery aneurysms at the ophthalmic segment” Interv Neuroradiol. 2021 Feb 21:1591019921996886. PMID: 33615875
 
Kato N, Nishimura K, Sonoda S, Kakizaki S, Nagayama G, Aoki K, Maruyama F, Ikemura A, Kan I, Kodama T, Kaku S, Yuki I, Ishibashi T, Otani K, Murayama Y. “Comparison of Clinical Outcomes After Stent-Assisted Coiling with 3 Types of Self-Expanding Laser-Cut Stents in Patients with Wide-Necked Intracranial Aneurysms”, World Neurosurg. 2021 Feb;146:e701-e707. PMID: 33181375
 
Kato N, Yuki I, Hataoka S, Dahmani C, Otani K, Abe Y, Kakizaki S, Nagayama G, Maruyama F, Ikemura A, Kan I, Kodama T, Ishibashi T, Murayama Y. “4D Digital Subtraction Angiography for the Temporal Flow Visualization of Intracranial Aneurysms and Vascular Malformations.” J Stroke Cerebrovasc Dis. 2020 Dec;29(12):105327. PMID: 32992207
 
Kan I, Ishibashi T, Sakuta K, Fujimura S, Yuki I, Kaku S, Kodama T, Kato N, Nishimura K, Aoki K, Sasaki Y, Karagiozov K, Murayama Y. “Preoperative Light Transmission Aggregometry Values Predict for Thromboembolic Complications After Stent-Assisted Coil Embolization.” World Neurosurg. 2020 Feb;134:e731-e738. PMID: 31704360
 
Ikemura A, Ishibashi T, Otani K, Yuki I, Kodama T, Kan I, Kato N, Murayama Y, “Delayed Leukoencephalopathy: A Rare Complication after Coiling of Cerebral Aneurysms” AJNR Am J Neuroradiol. 2020 Feb;41(2):286-292. doi: 0.3174/ajnr.A6386. Epub 2020 Jan 30.
Grant
Research Grant: Institute for Clinical and Translational Science (ICTS) Pilot Award (NIH Director’s Transformative Research Award initiative), Principle Investigator Ichiro Yuki MD, Co-principal investigator: Shuichi Suzuki MD PhD, Co-investigator Kousaku Ohkawa PhD, Frank P.K. Hsu MD, PhD , April 1st. 2019 – May 2020.“New Generation Liquid Embolic Material for the use of Endovascular Treatment: An organic polymer composite activated by the Ca2+ in the blood
Professional Societies
Society of Neurointerventional Surgery (SNIS)
American Stroke Association (AHA/ASA)
The Japanese Society for Neuroendovascular Therapy (JSNET)
The Japan Neurosurgical Society (JNS)
Last updated
03/10/2021