Sanghyuk Shin

Assistant Professor and Statistics Lead
Sue & Bill Gross School of Nursing


Phone: (949) 824-4734

University of California, Irvine
268 Berk Hall
Mail Code: 3959
Irvine, CA 92697
Research Interests
Infectious disease epidemiology, drug-resistant tuberculosis, TB/HIV co-infection, molecular diagnostics, community-based intervention trials, molecular epidemiology, social determinants
Shin SS, Modongo C, Baik Y, Allender C, Lemmer D, Colman RE, et al. Mixed infections are associated with poor treatment outcomes among newly diagnosed tuberculosis patients independent of pre-treatment heteroresistance. J Infect Dis. 2018 Available from:
Shin SS, Carpenter CL, Ekstrand ML, et al. Household Food Insecurity as Mediator of the Association Between Internalized Stigma and Opportunistic Infections. AIDS Behav. June 2018:1-8. doi:10.1007/s10461-018-2193-3. NIHMSID 973811.
Nyamathi AM, Salem BE, Ekstrand M, Yadav K, Le Y, Oleskowicz T, Shin SS. Correlates of Treatment Readiness Among Formerly Incarcerated Homeless Women. Criminal Justice and Behavior. 2018 Jul 1;45(7):969–83. NIHMS973145.
Shin SS, Modongo C, Zetola NM, Wang Q, Phologolo T, Kestler M, Ho-Foster A. High rates of exposure to tuberculosis patients among HIV-infected healthcare workers in Botswana. Int J Tuberc Lung Dis 2018;22(4):366-370. PMCID: PMC5868425.

Nyamathi AM, Shin SS, Smeltzer J, Salem B, Yadav K, Ekstrand M, Turner S, Faucette M. Achieving Drug and Alcohol Abstinence Among Recently Incarcerated Homeless Women: A Randomized Controlled Trial Comparing Dialectical Behavioral Therapy-Case Management With a Health Promotion (HP) Program. Nurs Res 2017;66(6):432-441. PMCID: PMC5679786.

Gu D, Shin SS*, Zetola NM*. Geospatial modelling in guiding health program strategies in resource-limited settings - The way forward. Ann of Transl Med 2017. doi: 10.21037/atm.2017.10.16. *Contributed equally.

Shin SS, Modongo C, Boyd R, Caiphus C, Kuate L, Kgwaadira B, Zetola NM. High Treatment Success Rates among HIV-infected Multidrug-resistant Tuberculosis Patients after Expansion of Antiretroviral Therapy in Botswana, 2006–2013. J Acquir Immune Defic Syndr. 2017;74(1):65-71. PMCID: PMC5140728.

Loeb S, Shin SS, Broyles DL, et al. Prostate Health Index (phi) Improves Multivariable Risk Prediction of Aggressive Prostate Cancer. BJU Int 2017 Jul;120(1):61-68. doi: 10.1111/bju.13676. PMCID: PMC5392379.

Shin SS, Modongo C, Zetola NM. The impact of mixed infections on the interpretation of molecular epidemiology studies of tuberculosis. Int J Tuberc Lung Dis 2016;20(3):423-424. PMCID: PMC4824546.

Grover S, Zetola NM, Modongo C, Chiyapo SP, Nsingo-Bvochora M, Narasimhamurthy M, Lin LL, Jarvis J, Shin SS, Roberson E. Collision of three pandemics: The coexistence of cervical cancer, HIV infection, and prior tuberculosis in the Sub-Saharan country of Botswana. Journal of Global Oncology 2016;2(1):47-50. doi:10.1200/JGO.2015.001701.

Shin SS, Chang AH, Ghosh JKC, Dubé MP, Yang OO, Bolan R, Kerndt PR. Isoniazid Therapy for Mycobacterium tuberculosis Infection in HIV Clinics, Los Angeles County, California. Int J Tuberc Lung Dis 2016;20(7):961-966. doi:10.5588/ijtld.15.0988. PMCID: PMC4905690.

Shin SS, Hsu T, Chavez E, Chang AH, Kerndt PR. Missed opportunity to prevent tuberculosis. American Journal of Public Health 2015;105(12):e3. PMCID: PMC4638250.

Shin SS, Modongo C, Ncube R, Sepako E, Klausner JD, Zetola NM. Advanced immune suppression is associated with increased prevalence of mixed-strain Mycobacterium tuberculosis infections among persons at high risk for drug-resistant TB in Botswana. J Infect Dis 2015;211(3):347-51. doi:10.1093/infdis/jiu421. PMCID: PMC4351373.
K01 AI118559 National Institute of Allergy and Infectious Diseases - NIH (PI: Shin) The Effect of Mixed-strain M. tuberculosis Infections on Treatment Outcomes 2/1/2015 – 1/31/2020 Role: Principal Investigator
R21 AI120838 National Institute of Allergy and Infectious Diseases - NIH (PI: Shin) Utility of Deep Sequencing for Detecting Heteroresistant Mycobacterium tuberculosis Infections among HIV-infected Persons 8/1/2015 – 7/30/2018 Role: Principal Investigator
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