Kai Kessenbrock

picture of Kai  Kessenbrock

Assistant Professor, Biological Chemistry
School of Medicine

Ph.D., Max Planck Institute of Neurobiology and LMU Munich, Germany, 2009

Email: kkessenb@uci.edu

University of California, Irvine
Sprague Hall 140- Lab
Mail Code: 1700
Irvine, CA 92697
Research Interests
Microenvironmental regulation of stem cells and cancer
Academic Distinctions
NIH-“Earl Stadtman Investigators“ Program Finalist, 2014

Hans Hench Prize for Clinical Immunology, Leipzig, Germany, 2010

Avrion Mitchison Prize from the Schering Foundation, Berlin, Germany, 2009

Susan G. Komen for the Cure Postdoctoral Fellow, 2009

Outstanding Paper Award from the Wekerle Foundation, 2009

Feodor Lynen Research Fellow, Alexander von Humboldt Foundation, 2008

Travel Awards from Keystone (2013), AACR (2012), International Proteolysis Society (2011, 2007) and Boehringer Ingelheim Foundation (2007)
Zena Werb Lab, University of California, San Francisco
Research Abstract
The Kessenbrock Lab studies cellular communication in single cell resolution in the context of normal tissue homeostasis and in breast cancer. We want to understand how stem cell behavior is extrinsically regulated by the microenvironment of the mammary stem cell niche and learn how the molecular composition of the niche changes during tumorigenesis. Our interdisciplinary research approach will identify biomarkers for early detection and may ultimately lead to the discovery of novel therapeutic approaches to treat or even prevent breast cancer before it develops.
K99/R00 Pathway to Independence Award from the NIH/NCI
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