Adrian Preda

picture of Adrian  Preda

Professor of Clinical Psychiatry, Psychiatry & Human Behavior
School of Medicine


M.D., Carol Davila University of Medicine and Pharmacy, 1992

Phone: (714) 456-5902
Email: apreda@hs.uci.edu

University of California, Irvine
UC Irvine Neuropsychiatric Center
101 The City Dr., Bldg 3, Room 313
Orange, CA 92697
Research Interests
schizophrenia, Alzheimer's dementia, clinical trials methodology
URLs
Awards and Honors
2016 “Physician of Excellence” by the Orange County Medical Association
2017 “Physician of Excellence” by the Orange County Medical Association
2019 “Physician of Excellence” by the Orange County Medical Association
2020 “Physician of Excellence” by the Orange County Medical Association
2021 “Physician of Excellence” by the Orange County Medical Association
2021 Distinguished Fellow, American Psychiatric Association
2022 “Physician of Excellence” by the Orange County Medical Association
Short Biography
Professor Adrian Preda completed his medical degree at Carol Davila University of Medicine and Pharmacy, Bucharest, Romania. He completed an internship in psychiatry at University of Rochester, Rochester, New York, and a residency in psychiatry at Yale University, where he served as the program wide Chief Resident and Yale New Haven Hospital Chief Resident in Psychiatry. He hold academic appointments at Yale and UT Southwestern, prior to joining the UC Irvine faculty. His areas of interest include schizophrenia and other psychotic disorders, cognitive disorders, and clinical trials.
Publications
Multi-model Order ICA: A Data-driven Method for Evaluating Brain Functional Network Connectivity Within and Between Multiple Spatial Scales. Brain Connect. 2021 Sep 19. Meng X, Iraji A, Fu Z, Kochunov P, Belger A, Ford J, McEwen S, Mathalon DH, Mueller BA, Pearlson G, Potkin SG, Preda A, Turner J, van Erp T, Sui J, Calhoun VD. PMID: 34541879.
 
A meta-analysis of deep brain structural shape and asymmetry abnormalities in 2,833 individuals with schizophrenia compared with 3,929 healthy volunteers via the ENIGMA Consortium. Hum Brain Mapp. 2021 Sep 08. Gutman BA, van Erp TGM, Alpert K, Ching CRK, Isaev D, Ragothaman A, Jahanshad N, Saremi A, Zavaliangos-Petropulu A, Glahn DC, Shen L, Cong S, Alnaes D, Andreassen OA, Doan NT, Westlye LT, Kochunov P, Satterthwaite TD, Wolf DH, Huang AJ, Kessler C, Weideman A, Nguyen D, Mueller BA, Faziola L, Potkin SG, Preda A, Mathalon DH, Bustillo J, Calhoun V, Ford JM, Walton E, Ehrlich S, Ducci G, Banaj N, Piras F, Piras F, Spalletta G, Canales-Rodríguez EJ, Fuentes-Claramonte P, Pomarol-Clotet E, Radua J, Salvador R, Sarró S, Dickie EW, Voineskos A, Tordesillas-Gutiérrez D, Crespo-Facorro B, Setién-Suero E, van Son JM, Borgwardt S, Schönborn-Harrisberger F, Morris D, Donohoe G, Holleran L, Cannon D, McDonald C, Corvin A, Gill M, Filho GB, Rosa PGP, Serpa MH, Zanetti MV, Lebedeva I, Kaleda V, Tomyshev A, Crow T, James A, Cervenka S, Sellgren CM, Fatouros-Bergman H, Agartz I, Howells F, Stein DJ, Temmingh H, Uhlmann A, de Zubicaray GI, McMahon KL, Wright M, Cobia D, Csernansky JG, Thompson PM, Turner JA, Wang L. PMID: 34498337.
 
Converting scores between the PANSS and SAPS/SANS beyond the positive/negative dichotomy. Psychiatry Res. 2021 Sep 01; 305:114199. Grot S, Giguère CÉ, Smine S, Mongeau-Pérusse V, Nguyen DD, Preda A, Potvin S, van Erp TGM, Fbirn , Orban P. PMID: 34536695.
 
Iatrogenic Delirium in Patients on Symptom-Triggered Alcohol Withdrawal Protocol: A Case Series. Cureus. 2021 Jun; 13(6):e15373. Wang A, Park A, Albert R, Barriga A, Goodrich L, Nguyen BN, Knox E, Preda A. PMID: 34249526.
 
Visual hallucinations are associated with hyperconnectivity between the amygdala and visual cortex in people with a diagnosis of schizophrenia. Schizophr Bull. 2015 Jan; 41(1):223-32. Ford JM, Palzes VA, Roach BJ, Potkin SG, van Erp TG, Turner JA, Mueller BA, Calhoun VD, Voyvodic J, Belger A, Bustillo J, Vaidya JG, Preda A, McEwen SC, Functional Imaging Biomedical Informatics Research Network , Mathalon DH. PMID: 24619536.
 
Autoconnectivity: A new perspective on human brain function. J Neurosci Methods. 2019 07 15; 323:68-76. Arbabshirani MR, Preda A, Vaidya JG, Potkin SG, Pearlson G, Voyvodic J, Mathalon D, van Erp T, Michael A, Kiehl KA, Turner JA, Calhoun VD. PMID: 31005575.
 
Multimodal neuromarkers in schizophrenia via cognition-guided MRI fusion. Nat Commun. 2018 08 02; 9(1):3028. Sui J, Qi S, van Erp TGM, Bustillo J, Jiang R, Lin D, Turner JA, Damaraju E, Mayer AR, Cui Y, Fu Z, Du Y, Chen J, Potkin SG, Preda A, Mathalon DH, Ford JM, Voyvodic J, Mueller BA, Belger A, McEwen SC, O'Leary DS, McMahon A, Jiang T, Calhoun VD. PMID: 30072715.
 
The use of referenced-EEG (rEEG) in assisting medication selection for the treatment of depression. J Psychiatr Res. 2011 Jan; 45(1):64-75. DeBattista C, Kinrys G, Hoffman D, Goldstein C, Zajecka J, Kocsis J, Teicher M, Potkin S, Preda A, Multani G, Brandt L, Schiller M, Iosifescu D, Fava M. PMID: 20598710.
 
The spatial chronnectome reveals a dynamic interplay between functional segregation and integration. Hum Brain Mapp. 2019 07; 40(10):3058-3077. Iraji A, Deramus TP, Lewis N, Yaesoubi M, Stephen JM, Erhardt E, Belger A, Ford JM, McEwen S, Mathalon DH, Mueller BA, Pearlson GD, Potkin SG, Preda A, Turner JA, Vaidya JG, van Erp TGM, Calhoun VD. PMID: 30884018.
 
Neural Correlates of Schizophrenia Negative Symptoms: Distinct Subtypes Impact Dissociable Brain Circuits. Mol Neuropsychiatry. 2015 Dec; 1(4):191-200. Shaffer JJ, Peterson MJ, McMahon MA, Bizzell J, Calhoun V, van Erp TG, Ford JM, Lauriello J, Lim KO, Manoach DS, McEwen SC, Mathalon DH, O'Leary D, Potkin SG, Preda A, Turner J, Voyvodic J, Wible CG, Belger A. PMID: 27606313.
 
The Function Biomedical Informatics Research Network Data Repository. Neuroimage. 2016 Jan 01; 124(Pt B):1074-1079. Keator DB, van Erp TGM, Turner JA, Glover GH, Mueller BA, Liu TT, Voyvodic JT, Rasmussen J, Calhoun VD, Lee HJ, Toga AW, McEwen S, Ford JM, Mathalon DH, Diaz M, O'Leary DS, Jeremy Bockholt H, Gadde S, Preda A, Wible CG, Stern HS, Belger A, McCarthy G, Ozyurt B, Potkin SG, FBIRN . PMID: 26364863.
 
Extracting spurious messages from noise and risk of schizophrenia-spectrum disorders in a prodromal population. Br J Psychiatry. 2007 Oct; 191:355-6. Hoffman RE, Woods SW, Hawkins KA, Pittman B, Tohen M, Preda A, Breier A, Glist J, Addington J, Perkins DO, McGlashan TH. PMID: 17906248.
 
The PRIME North America randomized double-blind clinical trial of olanzapine versus placebo in patients at risk of being prodromally symptomatic for psychosis. II. Baseline characteristics of the "prodromal" sample. Schizophr Res. 2003 May 01; 61(1):19-30. Miller TJ, Zipursky RB, Perkins D, Addington J, Woods SW, Hawkins KA, Hoffman R, Preda A, Epstein I, Addington D, Lindborg S, Marquez E, Tohen M, Breier A, McGlashan TH. PMID: 12648732.
 
Converting positive and negative symptom scores between PANSS and SAPS/SANS. Schizophr Res. 2014 Jan; 152(1):289-94. van Erp TG, Preda A, Nguyen D, Faziola L, Turner J, Bustillo J, Belger A, Lim KO, McEwen S, Voyvodic J, Mathalon DH, Ford J, Potkin SG, Fbirn . PMID: 24332632.
 
Tuning in to the voices: a multisite FMRI study of auditory hallucinations. Schizophr Bull. 2009 Jan; 35(1):58-66. Ford JM, Roach BJ, Jorgensen KW, Turner JA, Brown GG, Notestine R, Bischoff-Grethe A, Greve D, Wible C, Lauriello J, Belger A, Mueller BA, Calhoun V, Preda A, Keator D, O'Leary DS, Lim KO, Glover G, Potkin SG, FBIRN , Mathalon DH. PMID: 18987102.
 
Impact of autocorrelation on functional connectivity. Neuroimage. 2014 Nov 15; 102 Pt 2:294-308. Arbabshirani MR, Damaraju E, Phlypo R, Plis S, Allen E, Ma S, Mathalon D, Preda A, Vaidya JG, Adali T, Calhoun VD. PMID: 25072392.
 
Multimodal neuromarkers in schizophrenia via cognition-guided MRI fusion. Nat Commun. 2018 08 02; 9(1):3028. Sui J, Qi S, van Erp TGM, Bustillo J, Jiang R, Lin D, Turner JA, Damaraju E, Mayer AR, Cui Y, Fu Z, Du Y, Chen J, Potkin SG, Preda A, Mathalon DH, Ford JM, Voyvodic J, Mueller BA, Belger A, McEwen SC, O'Leary DS, McMahon A, Jiang T, Calhoun VD. PMID: 30072715.
 
The genetic architecture of the human cerebral cortex. Science. 2020 03 20; 367(6484). Grasby KL, Jahanshad N, Painter JN, Colodro-Conde L, Bralten J, Hibar DP, Lind PA, Pizzagalli F, Ching CRK, McMahon MAB, Shatokhina N, Zsembik LCP, Thomopoulos SI, Zhu AH, Strike LT, Agartz I, Alhusaini S, Almeida MAA, Alnæs D, Amlien IK, Andersson M, Ard T, Armstrong NJ, Ashley-Koch A, Atkins JR, Bernard M, Brouwer RM, Buimer EEL, Bülow R, Bürger C, Cannon DM, Chakravarty M, Chen Q, Cheung JW, Couvy-Duchesne B, Dale AM, Dalvie S, de Araujo TK, de Zubicaray GI, de Zwarte SMC, den Braber A, Doan NT, Dohm K, Ehrlich S, Engelbrecht HR, Erk S, Fan CC, Fedko IO, Foley SF, Ford JM, Fukunaga M, Garrett ME, Ge T, Giddaluru S, Goldman AL, Green MJ, Groenewold NA, Grotegerd D, Gurholt TP, Gutman BA, Hansell NK, Harris MA, Harrison MB, Haswell CC, Hauser M, Herms S, Heslenfeld DJ, Ho NF, Hoehn D, Hoffmann P, Holleran L, Hoogman M, Hottenga JJ, Ikeda M, Janowitz D, Jansen IE, Jia T, Jockwitz C, Kanai R, Karama S, Kasperaviciute D, Kaufmann T, Kelly S, Kikuchi M, Klein M, Knapp M, Knodt AR, Krämer B, Lam M, Lancaster TM, Lee PH, Lett TA, Lewis LB, Lopes-Cendes I, Luciano M, Macciardi F, Marquand AF, Mathias SR, Melzer TR, Milaneschi Y, Mirza-Schreiber N, Moreira JCV, Mühleisen TW, Müller-Myhsok B, Najt P, Nakahara S, Nho K, Olde Loohuis LM, Orfanos DP, Pearson JF, Pitcher TL, Pütz B, Quidé Y, Ragothaman A, Rashid FM, Reay WR, Redlich R, Reinbold CS, Repple J, Richard G, Riedel BC, Risacher SL, Rocha CS, Mota NR, Salminen L, Saremi A, Saykin AJ, Schlag F, Schmaal L, Schofield PR, Secolin R, Shapland CY, Shen L, Shin J, Shumskaya E, Sønderby IE, Sprooten E, Tansey KE, Teumer A, Thalamuthu A, Tordesillas-Gutiérrez D, Turner JA, Uhlmann A, Vallerga CL, van der Meer D, van Donkelaar MMJ, van Eijk L, van Erp TGM, van Haren NEM, van Rooij D, van Tol MJ, Veldink JH, Verhoef E, Walton E, Wang M, Wang Y, Wardlaw JM, Wen W, Westlye LT, Whelan CD, Witt SH, Wittfeld K, Wolf C, Wolfers T, Wu JQ, Yasuda CL, Zaremba D, Zhang Z, Zwiers MP, Artiges E, Assareh AA, Ayesa-Arriola R, Belger A, Brandt CL, Brown GG, Cichon S, Curran JE, Davies GE, Degenhardt F, Dennis MF, Dietsche B, Djurovic S, Doherty CP, Espiritu R, Garijo D, Gil Y, Gowland PA, Green RC, Häusler AN, Heindel W, Ho BC, Hoffmann WU, Holsboer F, Homuth G, Hosten N, Jack CR, Jang M, Jansen A, Kimbrel NA, Kolskår K, Koops S, Krug A, Lim KO, Luykx JJ, Mathalon DH, Mather KA, Mattay VS, Matthews S, Mayoral Van Son J, McEwen SC, Melle I, Morris DW, Mueller BA, Nauck M, Nordvik JE, Nöthen MM, O'Leary DS, Opel N, Martinot MP, Pike GB, Preda A, Quinlan EB, Rasser PE, Ratnakar V, Reppermund S, Steen VM, Tooney PA, Torres FR, Veltman DJ, Voyvodic JT, Whelan R, White T, Yamamori H, Adams HHH, Bis JC, Debette S, Decarli C, Fornage M, Gudnason V, Hofer E, Ikram MA, Launer L, Longstreth WT, Lopez OL, Mazoyer B, Mosley TH, Roshchupkin GV, Satizabal CL, Schmidt R, Seshadri S, Yang Q, Alzheimer’s Disease Neuroimaging Initiative , CHARGE Consortium , EPIGEN Consortium , IMAGEN Consortium , SYS Consortium , Parkinson’s Progression Markers Initiative , Alvim MKM, Ames D, Anderson TJ, Andreassen OA, Arias-Vasquez A, Bastin ME, Baune BT, Beckham JC, Blangero J, Boomsma DI, Brodaty H, Brunner HG, Buckner RL, Buitelaar JK, Bustillo JR, Cahn W, Cairns MJ, Calhoun V, Carr VJ, Caseras X, Caspers S, Cavalleri GL, Cendes F, Corvin A, Crespo-Facorro B, Dalrymple-Alford JC, Dannlowski U, de Geus EJC, Deary IJ, Delanty N, Depondt C, Desrivières S, Donohoe G, Espeseth T, Fernández G, Fisher SE, Flor H, Forstner AJ, Francks C, Franke B, Glahn DC, Gollub RL, Grabe HJ, Gruber O, Håberg AK, Hariri AR, et al. PMID: 32193296.
 
Higher Dimensional Meta-State Analysis Reveals Reduced Resting fMRI Connectivity Dynamism in Schizophrenia Patients. PLoS One. 2016; 11(3):e0149849. Miller RL, Yaesoubi M, Turner JA, Mathalon D, Preda A, Pearlson G, Adali T, Calhoun VD. PMID: 26981625.
 
Function biomedical informatics research network recommendations for prospective multicenter functional MRI studies. J Magn Reson Imaging. 2012 Jul; 36(1):39-54. Glover GH, Mueller BA, Turner JA, van Erp TG, Liu TT, Greve DN, Voyvodic JT, Rasmussen J, Brown GG, Keator DB, Calhoun VD, Lee HJ, Ford JM, Mathalon DH, Diaz M, O'Leary DS, Gadde S, Preda A, Lim KO, Wible CG, Stern HS, Belger A, McCarthy G, Ozyurt B, Potkin SG. PMID: 22314879.
 
Cortical Brain Abnormalities in 4474 Individuals With Schizophrenia and 5098 Control Subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium. Biol Psychiatry. 2018 11 01; 84(9):644-654. van Erp TGM, Walton E, Hibar DP, Schmaal L, Jiang W, Glahn DC, Pearlson GD, Yao N, Fukunaga M, Hashimoto R, Okada N, Yamamori H, Bustillo JR, Clark VP, Agartz I, Mueller BA, Cahn W, de Zwarte SMC, Hulshoff Pol HE, Kahn RS, Ophoff RA, van Haren NEM, Andreassen OA, Dale AM, Doan NT, Gurholt TP, Hartberg CB, Haukvik UK, Jørgensen KN, Lagerberg TV, Melle I, Westlye LT, Gruber O, Kraemer B, Richter A, Zilles D, Calhoun VD, Crespo-Facorro B, Roiz-Santiañez R, Tordesillas-Gutiérrez D, Loughland C, Carr VJ, Catts S, Cropley VL, Fullerton JM, Green MJ, Henskens FA, Jablensky A, Lenroot RK, Mowry BJ, Michie PT, Pantelis C, Quidé Y, Schall U, Scott RJ, Cairns MJ, Seal M, Tooney PA, Rasser PE, Cooper G, Shannon Weickert C, Weickert TW, Morris DW, Hong E, Kochunov P, Beard LM, Gur RE, Gur RC, Satterthwaite TD, Wolf DH, Belger A, Brown GG, Ford JM, Macciardi F, Mathalon DH, O'Leary DS, Potkin SG, Preda A, Voyvodic J, Lim KO, McEwen S, Yang F, Tan Y, Tan S, Wang Z, Fan F, Chen J, Xiang H, Tang S, Guo H, Wan P, Wei D, Bockholt HJ, Ehrlich S, Wolthusen RPF, King MD, Shoemaker JM, Sponheim SR, De Haan L, Koenders L, Machielsen MW, van Amelsvoort T, Veltman DJ, Assogna F, Banaj N, de Rossi P, Iorio M, Piras F, Spalletta G, McKenna PJ, Pomarol-Clotet E, Salvador R, Corvin A, Donohoe G, Kelly S, Whelan CD, Dickie EW, Rotenberg D, Voineskos AN, Ciufolini S, Radua J, Dazzan P, Murray R, Reis Marques T, Simmons A, Borgwardt S, Egloff L, Harrisberger F, Riecher-Rössler A, Smieskova R, Alpert KI, Wang L, Jönsson EG, Koops S, Sommer IEC, Bertolino A, Bonvino A, Di Giorgio A, Neilson E, Mayer AR, Stephen JM, Kwon JS, Yun JY, Cannon DM, McDonald C, Lebedeva I, Tomyshev AS, Akhadov T, Kaleda V, Fatouros-Bergman H, Flyckt L, Karolinska Schizophrenia Project , Busatto GF, Rosa PGP, Serpa MH, Zanetti MV, Hoschl C, Skoch A, Spaniel F, Tomecek D, Hagenaars SP, McIntosh AM, Whalley HC, Lawrie SM, Knöchel C, Oertel-Knöchel V, Stäblein M, Howells FM, Stein DJ, Temmingh HS, Uhlmann A, Lopez-Jaramillo C, Dima D, McMahon A, Faskowitz JI, Gutman BA, Jahanshad N, Thompson PM, Turner JA. PMID: 29960671
 
Randomized, double-blind trial of olanzapine versus placebo in patients prodromally symptomatic for psychosis. Am J Psychiatry. 2006 May; 163(5):790-9. McGlashan TH, Zipursky RB, Perkins D, Addington J, Miller T, Woods SW, Hawkins KA, Hoffman RE, Preda A, Epstein I, Addington D, Lindborg S, Trzaskoma Q, Tohen M, Breier A. PMID: 16648318.
 
Working memory and DLPFC inefficiency in schizophrenia: the FBIRN study. Schizophr Bull. 2009 Jan; 35(1):19-31. Potkin SG, Turner JA, Brown GG, McCarthy G, Greve DN, Glover GH, Manoach DS, Belger A, Diaz M, Wible CG, Ford JM, Mathalon DH, Gollub R, Lauriello J, O'Leary D, van Erp TG, Toga AW, Preda A, Lim KO, FBIRN . PMID: 19042912.
 
Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the ENIGMA consortium. Mol Psychiatry. 2016 Apr; 21(4):547-53. van Erp TG, Hibar DP, Rasmussen JM, Glahn DC, Pearlson GD, Andreassen OA, Agartz I, Westlye LT, Haukvik UK, Dale AM, Melle I, Hartberg CB, Gruber O, Kraemer B, Zilles D, Donohoe G, Kelly S, McDonald C, Morris DW, Cannon DM, Corvin A, Machielsen MW, Koenders L, de Haan L, Veltman DJ, Satterthwaite TD, Wolf DH, Gur RC, Gur RE, Potkin SG, Mathalon DH, Mueller BA, Preda A, Macciardi F, Ehrlich S, Walton E, Hass J, Calhoun VD, Bockholt HJ, Sponheim SR, Shoemaker JM, van Haren NE, Hulshoff Pol HE, Pol HE, Ophoff RA, Kahn RS, Roiz-Santiañez R, Crespo-Facorro B, Wang L, Alpert KI, Jönsson EG, Dimitrova R, Bois C, Whalley HC, McIntosh AM, Lawrie SM, Hashimoto R, Thompson PM, Turner JA. PMID: 26033243.
Professional Societies
Society of Biological Psychiatry
Schizophrenia International Research Society
International College of Neuropsychopharmacology
American Psychiatric Association
Other Experience
Chief Resident in Psychiaty
Yale University 1998—1999

Residency in Psychiatry
Yale University 1996—1999

Internship in Psychiatry
University of Rochester 1995—1996

Graduate Programs
Psychiatry

Last updated
11/10/2021