Shruti Gohil

picture of Shruti  Gohil

Associate Medical Director, Epidemiology & Infection Prevention, Infectious Diseases
School of Medicine

Assistant Professor, Infectious Diseases
School of Medicine


M.D.
M.P.H.

Email: skgohil@uci.edu

University of California, Irvine
333 City Park Blvd, West
City Tower Suite 400
Orange, CA 92868
Research Interests
Hospital Epidemiology and Infection Prevention, Sociodemographic and Clinical Contributors to Hospital Readmissions, and Epidemiology of Sepsis
Awards and Honors
1992 Four-year UC Regents Scholarship, University of California, Irvine
1997 Phi Beta Kappa, National Honor Society, University of California, Irvine
2006 Outstanding Resident Teacher of the Year, Internal Medicine, Univ. of California, Davis
2010 Winner, Best Abstract in Clinical Research, Infectious Disease Society of New York
2010 Travel Grant Award, Infectious Disease Society of America
2010 Best Research Poster, Second Place, Montefiore Medical Center Research Day
2011 Best Abstract, Young Investigator’s Symposium, Albert Einstein College of Medicine
2013 Outstanding Attending Teacher of the Year, Internal Medicine Residency Program, Univ. of California, Irvine
2015 Winner, Program Innovation Abstract, Second Place, 15th International Meeting on Simulation in
Healthcare
2016 SOAR Award, Nosocomial C. difficile Infection Reduction Project. UC Irvine Health
2017- Present NIH Loan Repayment Program Award
2017 ID Week Program Committee Choice Award. Plenary Presentation. SHEA Featured Oral Abstract, “The CDC SHIELD Orange County Project – Baseline Multi Drug-Resistant Organism (MDRO) Prevalence in a Southern California Region,” IDWeek (6th Annual Joint Meeting of IDSA, SHEA, HIVMA, and PIDS), October 6, 2017 (San Diego, CA).
2018 Team Award for Outstanding Achievement, Epidemiology & Infection Prevention, conferred by Chief Nursing Officer, UC Irvine Health
2018 Department of Medicine Chair’s Research Grant Award
2020 Award for Outstanding Service in Medical Education, UC Irvine School of Medicine
Short Biography
Dr. Gohil is an Assistant Professor in the Division of Infectious Diseases at UC Irvine School of Medicine and Associate Medical Director of Epidemiology & Infection Prevention. She earned her Medical Doctorate from Tufts University, School of Medicine, completed her residency in Internal Medicine at UC Davis, and a Clinical and Research Fellowship in Infectious Diseases at the Albert Einstein School of Medicine in New York City. In her current administrative role, she is leading UCI Health’s response to the COVID pandemic, including clinical and epidemiologic assessment of healthcare worker and patient management, COVID testing, exposure definition and response, contact tracing, infection prevention strategies to limit spread (e.g., PPE management, environmental handling and cleaning), and vaccination.
Dr. Gohil’s primary research priorities are dedicated to understanding what places individuals and populations at risk for infectious diseases and how to mitigate this risk at the earliest opportunity using applied epidemiology and patient-oriented outcomes research to develop innovative ways to evaluate, detect, and intervene in the acquisition and spread of healthcare-associated infections along the continuum of care. Specifically, Dr. Gohil’s has led state-wide population studies using large administrative datasets to examine modifiable risk factors associated with infection-related readmissions and sepsis. She is also the lead investigator of four separate CDC and NIH funded national cluster-randomized control trials (INSPIRE-ASP Trials: Pneumonia, UTI, Abdominal, and Skin/Soft Tissue Infections) that include modeling absolute patient risk for multi-drug resistant bacterial infections and creating real-time physician smart prompts to limit use of extended spectrum antibacterials. If successful, these trials will help change paradigms on appropriate antibiotic use in hospitalized patients.
Her research portfolio also includes a focus on device-associated infections across healthcare settings with an emphasis on the use of novel strategies to recognize and respond to infection prevention opportunities as early and swiftly as possible. She developed a novel scoring system (CLISA score, Central Line Insertion Site Assessment) to standardize the medical assessment of central lines and link nursing findings of high risk lines to physician action. This effort successfully linked preventive thinking to clinical response and dramatically reduced infection risk at participating facilities. Dr. Gohil also created the SAFER Lines mobile app that enables high-fidelity nursing photo-documentation, remote physician exam, and within-app ordering to respond to high risk central lines, which expanded the CLISA score from use in the hospital setting to post-discharge settings (cancer clinics and nursing homes). This telemedicine approach provides a novel strategy for infection prevention that emphasizes and promotes proactive processes for early detection of the pre-infection state and timely preventative response – a model with broad applicability to other infection syndromes.
Publications
1. Gohil, S.K., Pirofski, L. Emerging Findings in Fungal Pathogenesis. Report from the 48th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy and 46th Infectious Disease Society of America Joint Conference 2008. Journal of Invasive Fungal Infections 2009; 2:151-153.



2. Gohil, S.K., Heo, M., Schoenbaum, E., Pirofski, L. CD8+ T cells and Risk for Bacterial Pneumonia and All-Cause Mortality in HIV-Infected Women. J Acquir Immune Defic Syndr. 2012 Jun 1;60(2):191-8.



3. Yano, M. Gohil, S.K., Coleman, R., Pirofski, L 2011. Antibodies to Streptococcus pneumoniae capsular polysaccharide enhance quorum sensing. mBio 2(5):e00176-11.



4. Rohatgi, S., Gohil, S.K., Kuniholm, M., Schultz, H., Dufauda, C., Armourd, K., Badrie, S., Mailliard, R., Pirofski, L. Fc gamma receptor 3A Polymorphism and Risk for HIV-associated Cryptococcal Disease. mBio, 4(5):e00573-13.



5. Rhee, C, Gohil, S.K., Klompas, M. Regulatory Mandates for Sepsis Care – Reasons for Caution. New England Journal of Medicine. 370:1673-1676. May 1, 2014.



6. Gohil, S.K., Datta, R., Chenghua, C., Phelan, M., Nguyen, V., Rowther, A., Huang, S. Impact of Hospital Population Case-Mix, Including Poverty, on Hospital All-Cause and Infection-Related 30-Day Readmission Rates. Clinical Infectious Diseases. 2015 Oct 15;61(8):1235-43.



7. Gohil, S.K., Scott, S., Quan, K., Huang, S. Marked Reduction in Compliance with Central Line Insertion Practices (CLIP) When Accounting for Missing CLIP Data and Incomplete Capture of Lines. American Journal of Infection Control. 2015 Oct 27. pii: S0196-6553(15)00980-3.



8. Gohil, S.K., Okubo, S., Klish, S., Huang, S., Zahn, M. Healthcare Workers and Post-Elimination Era Measles: Lessons on Acquisition and Exposure Prevention. Clinical Infectious Diseases. 2016 Jan 15;62(2):166-72.



9. Gohil, S.K., Chenghua, C., Phelan, M., Rhee, C., Platt, R., Huang, S. Impact of Policies on the Rise of Sepsis Incidence, 2000-2010. Clinical Infectious Diseases. 2016 Mar 15;62 (6): 695-703.
 
10. Madeline, T., Nori, P., Wenzhu, M., Zukowski, E., Gohil, S.K., Sarwar, U., Weston, G., Urelly, R., Palombelli, M., Pierino, F., Parsons, V., Ehrlich, A., Ostrowsky, B., Corpuz, M., Piroski, L. Bundle in the Bronx: Impact of a Transition-of-Care Outpatient Parenteral Antibiotic Therapy Bundle on AllCause
30-Day Hospital Readmissions. Open Forum Infectious Diseases. 2017 May; DOI: 10.1093/ofid/ofx097.
 
11. Gohil, S.K., Singh, R., Chang, J, Gombosev, A., Tjoa, T., Zahn, M., Steger, P., Huang, S.S. Emergence of carbapenem-resistant Enterobacteriaceae in Orange County, CA, and support for early regional strategies to limit spread. American Journal of Infection Control. 2017 July; DOI: 10.1016/j.ajic.2017.06.004
 
12. Bartsch SM, McKinnell JA, Mueller LE, Miller LG, Gohil SK, Huang SS, Lee BY. Potential economic burden of carbapenem-resistant Enterobacteriaceae (CRE) in the United States. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 2017;23(1):48.e9-.e16.

13. Singh, RD, Jernigan, JA, Slayton, R, Stone, ND, McKinnell, JA, Miller, LG, Kleinman, K, Heim, L, Dutciuc, TD, Estevez, M, Gussin, G, Chang, J, Peterson, EM, Evans, K, Bruce Y Lee, Lee, BY, Mueller, LE, Bartsch, SM, Zahn, M, Janssen, L, Weinstein, RA, Hayden, MA, Gohil, SK, Park, S, Tam, S, Saavedra, R, Yamaguchi, Y, Custodio, H, Nguyen, J, Tjoa, T, He, J, O’Donnell, K, Coady, MH, Platt, R, Huang, SS. CDC Safety and Healthcare Epidemiology Prevention Research Development (SHEPheRD) Program, The CDC SHIELD Orange County Project – Baseline Multi Drug-Resistant Organism (MDRO) Prevalence in a Southern California Region, Open Forum Infectious Diseases, Volume 4, Issue suppl_1, Fall 2017, Pages S46 S47, https://doi.org/10.1093/ofid/ofx162.109

14. McKinnell, JA, Miller, LG, Singh, RD, Mendez, J, Franco, R, Gussin, G, Chang, J, Dutciuc, TD, Saavedra, R, Kleinman, K, Peterson, EM, Evans, Heim, L, Miner, A, Estevez, M, Custodio, H, Yamaguchi, S, Nguyen, J, Varasteh, A, Launer, B, Agrawal, S, Tjoa, T, He, J, Park, S, Tam, S, Gohil, SK, Stone, ND, Steinberg, K, Montgomery, M, Beecham, N, Huang, SS. When a Home is Not a Home: MultiDrug-Resistant Organism (MDRO) Colonization and Environmental Contamination in 28 Nursing Homes (NHs), Open Forum Infectious Diseases, Volume 4, Issue suppl_1, Fall 2017, Pages S42–S43, https://doi.org/10.1093/ofid/ofx162.103

15. Quan KA, Yim J, Merrill DG, Khusbu U, Madey K, Dickey L, Dangodara AA, Rudkin SE, O’Brien M, Thompson D, Parekh N, Albers CG, Wilson WC, Thrupp L, Bittencourt, CE, Huang, SS, Gohil, SK. Reductions in Clostridium difficile Infection (CDI) Rates Using Real-Time Automated Clinical Criteria Verification to Enforce Appropriate Testing. Infection Control and Hospital Epidemiology. 2018 May; 39(5): 625–627.

16. McKinnell, JA, Singh, RD, Miller, LG, Saavedra, R, Heim, L, Gussin, G, Lewis, B, Estevez, M, Catuna, TD, Mouth, K, Lee, E, He, J, Kleinman, K, Shimabukuro, J, Evans, K, Bittencourt, C, Baesu, C, Gohil, SK, Park, S, Tam, S, Robinson, PA, Slayton, R, Stone, ND, Jernigan, JA, Zahn, M, Janssen, L, ODonnell, K, Weinstein, RA, Hayden, MA, Lee, BY, Mueller, LE, Bartsch, SM, Peterson, EM, Huang, SS. The SHIELD Orange County Project: A Decolonization Strategy in 35 Hospitals and Nursing Homes Reduces Multi-Drug-Resistant Organism (MDRO) Prevalence in a Southern California Region, Open Forum Infectious Diseases, Volume 6, Issue Supplement_2, October 2019, Pages S23–S24, https://doi.org/10.1093/ofid/ofz359.052

17. McKinnell, JA, Singh, RD, Miller, LG, Kleinman, K, Gussin, G, He, J, Saavedra, R, Dutciuc, TD, Estevez, M, Chang, J, Heim, L, Yamaguchi, S, Custodio, H, Gohil, SK…. Huang, SS. The SHIELD Orange County Project –Multi Drug-Resistant Organism (MDRO) Prevalence in 21 Nursing Homes and Long Term Acute Care Facilities in Southern California. Clinical Infectious Diseases. Clinical Infectious Diseases, Volume 69, Issue 9, 1 November 2019, Pages 1566–1573, https://doi.org/10.1093/cid/ciz119

18. Gohil, SK, Yim, J, Quan, K, Espinoza, M, Thompson, DJ, Kong, AP, Bahadori, B, Tjoa, T, Paiji, C, Rudkin, S, Rashid, S, Hong, SS, Dickey, L, Alsharif, MN, Wilson, WC, Amin, AN, Chang, J, Khusbu, U, and Huang, SS. Impact of a Central Line Insertion Site Assessment (CLISA) Score on Localized Insertion Site Infection to Prevent Central Line Associated Bloodstream Infection. Infection Control and Hospital Epidemiology. 2019 Nov 8:1-8.
Grants
UCI School of Medicine Faculty Research Award
K-L2 ICTS
R01-AHRQ
NIH NRSA Training Grant (5T32)
Professional Societies
Infectious Disease Society of America
Society for Healthcare Epidemiologists of America
Other Experience
Assistant Professor, Infectious Diseases
University of California, Irvine 2010—Curr

Attending, Infectious Disease
Albert Einstein College of Medicine 2009—2010

Infectious Disease Research Fellow
Albert Einstein College of Medicine 2006—2009

Research Center
Health Policy Research Institute
Last updated
01/04/2021