Theo G.M. vanErp

picture of Theo G.M. vanErp

Associate Professor, Psychiatry & Human Behavior
School of Medicine


Ph.D., University of Utrecht, Utrecht, The Netherlands, 2007, Clinical Neuroscience
M.A., University of Nijmegen, 1995, Neuropsychology

Phone: (949) 824-3331
Fax: (949) 924-3324
Email: tvanerp@uci.edu

University of California, Irvine
School of Medicine
Department of Psychiatry and Human Behavior
Irvine Hall, room 109
Mail Code: 3950
Irvine, CA 92697
Research Interests
Psychosis, Schizophrenia, Bipolar disorder, Major Depressive Disorder, Neuroimaging, Imaging Genetics, Hippocampus, Down Syndrome
URLs
CV
Academic Distinctions
2001 - Human Brain Mapping Travel Award
2015 - Nomination for Best Poster Award at the 70th annual meeting of the Society of Biological Psychiatry
2017 - Chancellor's Award for Excellence in Undergraduate Research
2018 - Fellow Center for the Neurobiology of Learning and Memory
2020 - Somerfeld-Ziskind Award, Society of Biological Psychiatry
Research Abstract
Dr. Theo G.M. van Erp joined the University of California Irvine Department of Psychiatry and Human Behavior in 2010. He received his Master’s in neuropsychology from the University of Nijmegen in 1995. He received his doctorate in clinical neuroscience from the University of Utrecht in 2007 and continued working on several multi-center brain imaging projects as an Assistant Researcher at the University of California Los Angeles between 2007-2010. In 2010, he started the Clinical Translational Neuroscience Laboratory with a research program focused on imaging and imaging genetics in psychiatric disorders.

The primary aim of Dr. Van Erp’s Clinical Translational Neuroscience Laboratory is to understand the mechanisms underlying psychotic and affective disorders such as schizophrenia, bipolar disorder, and major depressive disorder. To achieve this aim, he conducts structural neuroimaging, functional neuroimaging, and neurocognitive studies. Dr. Van Erp collaborates with investigators locally at the University of California Irvine, nationally, and internationally with regard to neuroimaging, neurocognition, and genomic research.
Publications
Gutman BA, van Erp TGM, Alpert K, Ching CRK, Isaev D, Ragothaman A, Jahanshad N, Saremi A, Zavaliangos-Petropulu A, Glahn DC, Shen L, Cong S, Alnaes D, Andreassen OA, Doan NT, Westlye LT, Kochunov P, Satterthwaite TD, Wolf DH, Huang AJ, Kessler C, Weideman A, Nguyen D, Mueller BA, Faziola L, Potkin SG, Preda A, Mathalon DH, Bustillo J, Calhoun V, Ford JM, Walton E, Ehrlich S, Ducci G, Banaj N, Piras F, Piras F, Spalletta G, Canales-Rodríguez EJ, Fuentes-Claramonte P, Pomarol-Clotet E, Radua J, Salvador R, Sarró S, Dickie EW, Voineskos A, Tordesillas-Gutiérrez D, Crespo-Facorro B, Setién-Suero E, van Son JM, Borgwardt S, Schönborn-Harrisberger F, Morris D, Donohoe G, Holleran L, Cannon D, McDonald C, Corvin A, Gill M, Filho GB, Rosa PGP, Serpa MH, Zanetti MV, Lebedeva I, Kaleda V, Tomyshev A, Crow T, James A, Cervenka S, Sellgren CM, Fatouros-Bergman H, Agartz I, Howells F, Stein DJ, Temmingh H, Uhlmann A, de Zubicaray GI, McMahon KL, Wright M, Cobia D, Csernansky JG, Thompson PM, Turner JA, Wang L. A meta-analysis of deep brain structural shape and asymmetry abnormalities in 2,833 individuals with schizophrenia compared with 3,929 healthy volunteers via the ENIGMA Consortium. Hum Brain Mapp [Internet]. 2021 Sep 8; Available from: http://dx.doi.org/10.1002/hbm.25625

ENIGMA Clinical High Risk for Psychosis Working Group, Jalbrzikowski M, Hayes RA, Wood SJ, Nordholm D, Zhou JH, Fusar-Poli P, Uhlhaas PJ, Takahashi T, Sugranyes G, Kwak YB, Mathalon DH, Katagiri N, Hooker CI, Smigielski L, Colibazzi T, Via E, Tang J, Koike S, Rasser PE, Michel C, Lebedeva I, Hegelstad WTV, de la Fuente-Sandoval C, Waltz JA, Mizrahi R, Corcoran CM, Resch F, Tamnes CK, Haas SS, Lemmers-Jansen ILJ, Agartz I, Allen P, Amminger GP, Andreassen OA, Atkinson K, Bachman P, Baeza I, Baldwin H, Bartholomeusz CF, Borgwardt S, Catalano S, Chee MWL, Chen X, Cho KIK, Cooper RE, Cropley VL, Dolz M, Ebdrup BH, Fortea A, Glenthøj LB, Glenthøj BY, de Haan L, Hamilton HK, Harris MA, Haut KM, He Y, Heekeren K, Heinz A, Hubl D, Hwang WJ, Kaess M, Kasai K, Kim M, Kindler J, Klaunig MJ, Koppel A, Kristensen TD, Kwon JS, Lawrie SM, Lee J, León-Ortiz P, Lin A, Loewy RL, Ma X, McGorry P, McGuire P, Mizuno M, Møller P, Moncada-Habib T, Muñoz-Samons D, Nelson B, Nemoto T, Nordentoft M, Omelchenko MA, Oppedal K, Ouyang L, Pantelis C, Pariente JC, Raghava JM, Reyes-Madrigal F, Roach BJ, Røssberg JI, Rössler W, Salisbury DF, Sasabayashi D, Schall U, Schiffman J, Schlagenhauf F, Schmidt A, Sørensen ME, Suzuki M, Theodoridou A, Tomyshev AS, Tor J, Værnes TG, Velakoulis D, Venegoni GD, Vinogradov S, Wenneberg C, Westlye LT, Yamasue H, Yuan L, Yung AR, van Amelsvoort TAMJ, Turner JA, van Erp TGM, Thompson PM, Hernaus D. Association of Structural Magnetic Resonance Imaging Measures With Psychosis Onset in Individuals at Clinical High Risk for Developing Psychosis: An ENIGMA Working Group Mega-analysis. JAMA Psychiatry. 2021 Jul 1;78(7):753–66.

Nakahara S, Turner JA, Calhoun VD, Lim KO, Mueller B, Bustillo JR, O'Leary DS, McEwen S, Voyvodic J, Belger A, Mathalon DH, Ford JM, Macciardi F, Matsumoto M, Potkin SG, van Erp TGM. Dentate gyrus volume deficit in schizophrenia. Psychol Med. 2019 Jun 3;:1-11. doi: 10.1017/S0033291719001144. [Epub ahead of print] PubMed PMID: 31155012; PubMed Central PMCID: PMC7068799.

Nakahara S, Matsumoto M, van Erp TGM. Hippocampal subregion abnormalities in schizophrenia: A systematic review of structural and physiological imaging studies. Neuropsychopharmacol Rep. 2018 Dec;38(4):156-166. doi: 10.1002/npr2.12031. Epub 2018 Sep 25. PubMed PMID: 30255629; PubMed Central PMCID: PMC7021222.

van Erp TGM, Walton E, Hibar DP, Schmaal L, Jiang W, Glahn DC, Pearlson GD, Yao N, Fukunaga M, Hashimoto R, Okada N, Yamamori H, Bustillo JR, Clark VP, Agartz I, Mueller BA, Cahn W, de Zwarte SMC, Hulshoff Pol HE, Kahn RS, Ophoff RA, van Haren NEM, Andreassen OA, Dale AM, Doan NT, Gurholt TP, Hartberg CB, Haukvik UK, Jørgensen KN, Lagerberg TV, Melle I, Westlye LT, Gruber O, Kraemer B, Richter A, Zilles D, Calhoun VD, Crespo-Facorro B, Roiz-Santiañez R, Tordesillas-Gutiérrez D, Loughland C, Carr VJ, Catts S, Cropley VL, Fullerton JM, Green MJ, Henskens FA, Jablensky A, Lenroot RK, Mowry BJ, Michie PT, Pantelis C, Quidé Y, Schall U, Scott RJ, Cairns MJ, Seal M, Tooney PA, Rasser PE, Cooper G, Shannon Weickert C, Weickert TW, Morris DW, Hong E, Kochunov P, Beard LM, Gur RE, Gur RC, Satterthwaite TD, Wolf DH, Belger A, Brown GG, Ford JM, Macciardi F, Mathalon DH, O'Leary DS, Potkin SG, Preda A, Voyvodic J, Lim KO, McEwen S, Yang F, Tan Y, Tan S, Wang Z, Fan F, Chen J, Xiang H, Tang S, Guo H, Wan P, Wei D, Bockholt HJ, Ehrlich S, Wolthusen RPF, King MD, Shoemaker JM, Sponheim SR, De Haan L, Koenders L, Machielsen MW, van Amelsvoort T, Veltman DJ, Assogna F, Banaj N, de Rossi P, Iorio M, Piras F, Spalletta G, McKenna PJ, Pomarol-Clotet E, Salvador R, Corvin A, Donohoe G, Kelly S, Whelan CD, Dickie EW, Rotenberg D, Voineskos AN, Ciufolini S, Radua J, Dazzan P, Murray R, Reis Marques T, Simmons A, Borgwardt S, Egloff L, Harrisberger F, Riecher-Rössler A, Smieskova R, Alpert KI, Wang L, Jönsson EG, Koops S, Sommer IEC, Bertolino A, Bonvino A, Di Giorgio A, Neilson E, Mayer AR, Stephen JM, Kwon JS, Yun JY, Cannon DM, McDonald C, Lebedeva I, Tomyshev AS, Akhadov T, Kaleda V, Fatouros-Bergman H, Flyckt L, Busatto GF, Rosa PGP, Serpa MH, Zanetti MV, Hoschl C, Skoch A, Spaniel F, Tomecek D, Hagenaars SP, McIntosh AM, Whalley HC, Lawrie SM, Knöchel C, Oertel-Knöchel V, Stäblein M, Howells FM, Stein DJ, Temmingh HS, Uhlmann A, Lopez-Jaramillo C, Dima D, McMahon A, Faskowitz JI, Gutman BA, Jahanshad N, Thompson PM, Turner JA. Cortical Brain Abnormalities in 4474 Individuals With Schizophrenia and 5098 Control Subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium. Biol Psychiatry. 2018 Nov 1;84(9):644-654. doi: 10.1016/j.biopsych.2018.04.023. Epub 2018 May 14. PubMed PMID: 29960671; PubMed Central PMCID: PMC6177304.

Nakahara S, Medland S, Turner JA, Calhoun VD, Lim KO, Mueller BA, Bustillo JR, O'Leary DS, Vaidya JG, McEwen S, Voyvodic J, Belger A, Mathalon DH, Ford JM, Guffanti G, Macciardi F, Potkin SG, van Erp TGM. Polygenic risk score, genome-wide association, and gene set analyses of cognitive domain deficits in schizophrenia. Schizophr Res. 2018 Nov;201:393-399. doi: 10.1016/j.schres.2018.05.041. Epub 2018 Jun 12. PubMed PMID: 29907492; PubMed Central PMCID: PMC6252137.

van Erp TG, Hibar DP, Rasmussen JM, Glahn DC, Pearlson GD, Andreassen OA, Agartz I, Westlye LT, Haukvik UK, Dale AM, Melle I, Hartberg CB, Gruber O, Kraemer B, Zilles D, Donohoe G, Kelly S, McDonald C, Morris DW, Cannon DM, Corvin A, Machielsen MW, Koenders L, de Haan L, Veltman DJ, Satterthwaite TD, Wolf DH, Gur RC, Gur RE, Potkin SG, Mathalon DH, Mueller BA, Preda A, Macciardi F, Ehrlich S, Walton E, Hass J, Calhoun VD, Bockholt HJ, Sponheim SR, Shoemaker JM, van Haren NE, Pol HE, Ophoff RA, Kahn RS, Roiz-Santiañez R, Crespo-Facorro B, Wang L, Alpert KI, Jönsson EG, Dimitrova R, Bois C, Whalley HC, McIntosh AM, Lawrie SM, Hashimoto R, Thompson PM, Turner JA. Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the ENIGMA consortium. Mol Psychiatry. 2016 Apr;21(4):585. doi: 10.1038/mp.2015.118. Epub 2015 Aug 18. PubMed PMID: 26283641; PubMed Central PMCID: PMC5751698.

van Erp TG, Guella I, Vawter MP, Turner J, Brown GG, McCarthy G, Greve DN, Glover GH, Calhoun VD, Lim KO, Bustillo JR, Belger A, Ford JM, Mathalon DH, Diaz M, Preda A, Nguyen D, Macciardi F, Potkin SG. Schizophrenia miR-137 locus risk genotype is associated with dorsolateral prefrontal cortex hyperactivation. Biol Psychiatry. 2014 Mar 1;75(5):398-405. doi: 10.1016/j.biopsych.2013.06.016. Epub 2013 Aug 1. PubMed PMID: 23910899; PubMed Central PMCID: PMC4428556.
Grants
R21 MH097196. “High-Resolution Functional Imaging of Hippocampal Subfields in Schizophrenia”. Funded by: NIH/NIMH. Funding Period: 04/10/2012-01/31/2015.
R21 MH118674. “Specificity of Hippocampal Subregion Cerebral Blood Volume Abnormalities in Psychiatric Disorders”. Funded by: NIH/NIMH. Funding Period: 05/01/2019-04/30/2021.
R01 MH121246. “ENIGMA-COINSTAC: Advanced Worldwide Transdiagnostic Analysis of Valence System Brain Circuits”. Funded by NIH/NIMH. Funding Period: 08/02/2019-05/31/2024.
Professional Societies
Society of Biological Psychiatry (Member)
Organization for Human Brain Mapping (Member)
Last updated
11/10/2021