Stephanie Y. Lu

picture of Stephanie Y. Lu

Associate Professor, Division of Retina, Ophthalmology
School of Medicine

M.D., UC San Diego, 2004
B.S., UCLA, 1997, Biochemistry

Phone: (949) 824-6256
Fax: (949) 824-4015
Email: sylu@uci.edu

University of California, Irvine
Gavin Herbert Eye Institute
850 Health Sciences Road
Mail Code: 4375
Irvine, CA 92697
Research Interests
age related macular degeneration, diabetic retinopathy, macular hole, epiretinal membrane, macular dystrophy, uveitis
Academic Distinctions
Board Certified in Ophthalmology
Publications
The ARPE-19 H vs J cybrid plus/minus cisplatin paper has been accepted. July 5, 2019.
 
Shen E, Tsao S, Kuppermann BD, Lu SY. A case of multifocal central serous chorioretinopathy from a progestin-only contraceptive device. New Frontiers in Ophthalmology 2019 doi: 10.15761/NFO.1000235. Case Report ISSN: 2397-2092. Volume 5: 1-3. Published: June 27, 2019
 
Nashine S, Cohen P, Chwa M, Lu SY, Nesburn AB, Kuppermann BD, Kenney MC. Humanin G (HNG) protects age-related macular degeneration (AMD) transmitochondrial ARPE-19 cybrids from mitochondrial and cellular damage. Cell Death Dis. 2017 Jul 20;8(7):e2951. doi: 10.1038/cddis.2017.348.
 
Ngai P, Muniz-Castro H, Lu SY. Submacular Hemorrhage Following Cataract Surgery in a Patient with Long Axial Length. New Front Ophthalmol. June 26, 2017 doi: 10.15761/NFO.1000166 Volume 3(3): 1-4.
 
Nashine S, Chwa M, Kazemian M, Thaker K, Lu SY, Nesburn A, Kuppermann BD, Kenney MC. Differential Expression of Complement Markers in Normal and AMD Transmitochondrial Cybrids. PLoS One. 2016 Aug 3;11(8):e0159828. doi: 10.1371/journal.pone.0159828. eCollection 2016. PMID: 27486856(Impact factor 3.5)
 
Patel A, Nguyen C, Lu SY, Central retinal vein occlusion: A review of current Evidence-based treatment options. Middle East African Journal of Ophthalmology, Volume 23, Issue 1, Jan/March 2016, page(s): 44-48.
 
Haider A, Bababeygy SR and Lu SY. Cystoid Macular Edema and Macular Pigmentation Associated with nab-Paclitaxel Therapy. Retinal Cases Brief Reports, 2015 Summer; 9(3):220-2
 
Haider A, Bababeygy SR, Lu SY. Cystoid Macular Edema Following Silicone Oil Tamponade For Retinal Detachment Surgery. Austin J Clin Ophthalmol. Feb 2015;2(1): 1042.
 
Lu SY, Azada MC, Ou S-H. Ignatius.
Case Report. Choroidal metastasis response to crizotinib in a ROS1-rearranged NSCLC patient. Lung Cancer 2015 Feb;87(2):207-9
 
Bressler SB, Almukhtar T, Bhorade A, Bressler NM, Glassman AR, Huang SS, Jampol LM, Kim JE, Melia M; Diabetic Retinopathy Clinical Research Network Investigators (including Lu SY). Repeated intravitreous ranibizumab injections for diabetic macular edema and the risk of sustained elevation of intraocular pressure or the need for ocular hypotensive treatment. JAMA Ophthalmol. 2015 May;133(5):589-97.
Grants
Lu S, sub-investigator:A Phase II, Randomized, Single-Masked, Sham-Controlled Study of the Safety, Tolerability and Evidence of Activity of Intravitreal APL-2 Therapy in Patients with Geographic Atrophy (GA)
Lu S, sub-investigator:A Two-Year, Randomized, Double-Masked, Multicenter, Three-Arm Study Comparing the Efficacy and Safety of RTH258 versus Aflibercept in Subjects with Neovascular Age-Related Macular Degeneration (RTH258-C001)
Lu S, sub-investigator: A PHASE RANDOMIZED, DOUBLE-MASKED, PLACEBO-CONTROLLED MULTICENTER CLINICAL TRIAL DESIGNED TO EVALUATE THE SAFETY AND EXPLORATORY EFFICACY OF LUMINATE® (ALG-1001) IN INDUCING PVD IN SUBJECTS WITH NON-PROLIFERATIVE DIABETIC RETINOPATHY
Lu S, sub-investigator: A PHASE III, MULTICENTER, RANDOMIZED, DOUBLE-MASKED, SHAM-CONTROLLED STUDY TO ASSESS THE EFFICACY AND SAFETY OF LAMPALIZUMAB ADMINISTERED INTRAVITREALLY TO PATIENTS WITH GEOGRAPHIC ATROPHY SECONDARY TO AGE-RELATED MACULAR DEGENERATION
Lu S, sub-investigator: A Multi-Center, Two-Stage, Open-Label Phase 1 and Randomized, Active Controlled, Masked Phase II Study to Evaluate the Safety and Efficacy of Intravitreal Implantation of NT-503-3 Encapsulated Cell Technology Compared with Eylea® for the Treatment of Recurrent Subfoveal Choroidal Neovascualarization (CNV) Secondary to Age-Related Macular Degeneration (AMD)
Lu S, sub-investigator: A PHASE 3 RANDOMIZED, DOUBLE-MASKED, CONTROLLED TRIAL TO ESTABLISH THE SAFETY AND EFFICACY OF INTRAVITREOUS ADMINISTRATION OF FOVISTATM (ANTI PDGF-B PEGYLATED APTAMER) ADMINISTERED IN COMBINATION WITH EITHER AVASTIN® OR EYLEA® COMPARED TO AVASTIN® OR EYLEA® MONOTHERAPY IN SUBJECTS WITH SUBFOVEAL NEOVASCULAR AGE-RELATED MACULAR DEGENERATION
Lu S, sub-investigator:A PHASE 2, DOUBLE-MASKED, RANDOMIZED, DOUBLE-MASKED, CONTROLLED, MULTIPLE-DOSE, REGIMEN-RANGING STUDY OF THE EFFICACY AND SAFETY OF INTRAVITREAL REGN2176-3 IN PATIENTS WITH NEOVASCULAR AGE-RELATED MACULAR DEGENERATION
Professional Societies
American Academy of Ophthalmology
American Society of Retina Specialists
Association for Research in Vision and Ophthalmology
Orange County Medical Association
Association of University Professors of Ophthalmology
Club Vit
California Medical Association
Other Experience
Fellowship in Vitreoretinal Surgery and Diseases
UC Irvine

Research Center
Gavin Herbert Eye Institute
Last updated
07/16/2019