Kristen M. Kelly

picture of Kristen M. Kelly

Chair, Dermatology
School of Medicine

Professor, Dermatology
School of Medicine

M.D., UCLA, 1993

Phone: (949) 824-7980

University of California, Irvine
118 Medical Surge I
Mail Code: 1475
Irvine, CA 92697
Research Interests
Cutaneous Angiogenesis; Vascular Birthmarks; Photodynamic therapy of cutaneous lesions
Academic Distinctions
1987 American Heart Association Research Scholarship

1989 Phi Beta Kappa

1989 Summa Cum Laude

1993 Alpha Omega Alpha Honor Society

1994 Outstanding Intern of the Year

1997 Outstanding Resident Teacher of the Year

2008 Physician of Excellence – Orange County Medical Association

2008 ASLMS Presidential Citation

2008 Key Professional Media Super Doctor

2009 Dr. Horace Furumoto Innovations Professional Development Award American Society for Laser Medicine and Surgery

2010-2018 Physician of Excellence – Orange County Medical Association

2011-Present Castle Connolly’s Top Doctors

2011 Faculty Leader for the Best Student/Resident paper submitted in the Cutaneous Laser Surgery section for the 31st ASLMS Annual Conference

2011 Institute for Clinical and Translational Science Mentoring Award

2013 Faculty Oversight for Best Student/Resident Cutaneous Laser Surgery Award

2016 ASLMS Excellence In Education Award

2017 Clinical Faculty Teaching Award UC Irvine Department of Dermatology

2018 Leon Goldman Memorial Award – American Society for Laser Medicine and Surgery

2019 Honoree of the Sturge Weber Foundation

2019 Orange Coast Magazine Top Women in Healthcare and Wellness

2020 Selected as Key Note Speaker for the Women in Energy Based Devices Forum, American Society for Lasers in Medicine and Surgery
2019-2020 Best Doctors in America
Journal Publications:
1. Cesario-Kelly KM, Nelson JS. Q-Switched Laser Treatment of Tattoos, Lasers in Medicine and Science, 12:89-98, 1997.

2. Kelly KM, Nelson JS. Carbon Dioxide Laser Resurfacing of Rhytides and Photodamaged Skin. Lasers in Medicine and Science 1998: 13, 232-241.

3. Nelson JS, Kelly KM. Q-Switched Nd:YAG Laser Treatment of a Medium Congenital Nevus. Dermatologic Surgery 1999: 25, 274-276.

4. Kelly KM, Nelson JS, Lask GP, Geronemus R, Bernstein LJ. Cryogen Spray Cooling in Combination with NonAblative Laser Treatment of Facial Wrinkles. Archives of Dermatology 1999:135, 691-694.

5. Kelly KM, Nelson JS. Critical Review of Lasers in Dermatology. In T.P. Ryan, ed. Matching the Energy Source to the Clinical Need, Bellingham, WA: SPIE Optical Engineering Press, 2000, 3-23.

6. Kelly KM, Nelson JS. An Update on the Clinical Management of Port Wine Stains, Lasers in Medical Science 2000: 15,220-226.

7. Majaron B, Verkruysse W, Kelly KM, Nelson JS. Er:YAG Laser Skin Resurfacing Using Repetitive Long-Pulse Exposure and Cryogen Spray Cooling: II. Theoretical Analysis. Lasers in Surgery and Medicine, 2001:29,131-137.

8. Majaron B, Kelly KM, Park HB, Verkruysse W, Nelson JS. Er:YAG Laser Skin Resurfacing Using Repetitive Long-Pulse Exposure and Cryogen Spray Cooling: I. Histological Study. Lasers in Surgery and Medicine, 2001:29, 121-130.

9. Nelson, JS, Majaron B, Kelly KM. Active Skin Cooling in Conjunction with Laser Dermatologic Surgery: Methodology and Clinical Results. Seminars in Cutaneous Medicine and Surgery 2000:19,253-266.

10. Nelson JS, Kelly KM, Zhao Y, Chen Z. Imaging Blood Flow in Human Port Wine Stain In-situ and In Real-time Using Optical Doppler Tomography. Archives of Dermatology 2001:137, 741-744.

11. Chang CJ, Kelly KM, Nelson JS. Cryogen Spray Cooling and Pulsed Dye Laser Treatment of Cutaneous Hemangiomas. Annals of Plastic Surgery 2001:46, 577-583.

12. Kelly KM, Majaron Boris, Nelson JS. Nonablative laser and light rejuvenation. Archives of Facial Plastic Surgery 2001: 3, 230-235.

13. Kelly KM, Nanda VS, Nelson JS. Treatment of Port Wine Stain Birthmarks Using the 1.5 ms Pulsed Dye Laser at High Fluences in Combination with Cryogen Spray Cooling. Dermatol Surg 2002: 28, 309-313.

14. Chang C-J, Kelly KM, van Gemert MJC, Nelson JS. Comparing the Effectiveness of 585 versus 595 nm Pulsed Dye Laser in Conjunction with Cryogen Spray Cooling During Port-Wine Stain Treatment. Lasers in Surgery and Medicine 2002:31, 352-358.

15. Nelson JS, Majaron B, Kelly KM. What is Non-ablative Photorejuvenation of Human Skin? Seminars in Cutaneous Medicine and Surgery: 2002:21, 238-250.

16. Kao B, Kelly KM, Majaron B, Nelson JS. Novel Model for Evaluation of Epidermal Preservation and Dermal Collagen Remodeling Following Photorejuvenation of Human Skin. Lasers in Surgery and Medicine:2003:32,115-119.

17. Jung WG, Kao B, Kelly KM, Nelson JS, Chen Z. Optical coherence tomography for in vitro monitoring of wound healing after laser irradiation. IEEE J Sel Topics Quant Electr:2003:9,222-226.

18. Choi B, Majaron B, Vargas G, Jung B, Stumpp O, Kang NM, Kelly KM, Welch AJ, Nelson JS. Photothermal tomography for imaging of cutaneous blood vessels: Preliminary in vivo results. Proceedings SPIE 2003:5047, 350-361.

19. Kelly KM, Nelson, JS, Svaasand LO. Optimization of safety for laser treatment in conjunction with cryogen spray cooling. Archives of Dermatology 2003:139, 1372-1373.

20. Selim MM, Kelly KM, Nelson JS, Wendelschafer-Crabb G, Kennedy WR, Zelickson BD. Confocal microscopy study of nerves and blood vessels in untreated and treated port wine stains: preliminary observations. Dermatologic Surgery 2004: 30, 892-7.

21. Kelly KM, Nelson JS, Svaasand LO. Further Investigation of Pigmentary Changes After Alexandrite Laser Hair Removal in Conjunction with Cryogen Spray Cooling. Dermatologic Surgery 2004:30, 581-2.

22. Jung B, Choi B, Durin AJ, Kelly KM, Nelson JS. Characterization of Port Wine Stain Skin Erythema and Melanin Content Using Cross-Polarized Diffuse Reflectance Imaging. Lasers Surg Med, 2004:34, 174-181.

23. Kao B, Aguilar G, Kelly KM, Hosaka Y, Barr R, Nelson JS. In vitro evaluation of cryogen spray cooling exposure on model human skin. Lasers in Surgery and Medicine; 2004:34, 146-154.

24. Kimel S, Svaasand LO, Kelly KM, Nelson JS. Synergistic photodynamic and photothermal treatment of port wine stain? Lasers in Surgery and Medicine; 2004:34, 80-82.

25. Khan MH, Choi B, Chess S, Kelly KM, McCullough J, Nelson JS. Optical clearing of in vivo human skin: implications for light based diagnostic imaging and therapeutics. Lasers in Surgery and Medicine; 2004: 34, 83-85.

26. Kelly KM, Kimel S, Smith T, Stacy A, Hammer-Wilson MJ, Svaasand LO, Nelson JS. Combined Photodynamic and Photothermal Induced Injury Enhances Damage to In Vivo Model Blood Vessels. Lasers in Surgery and Medicine 2004:34, 407-13.

27. Khan MH, Chess S, Choi B, Kelly KM, Nelson JS. Can topically applied optical clearing agents increase the epidermal damage threshold and enhance therapeutic efficacy? Lasers in Surgery and Medicine 2004:35, 93-95.

28. Smith TK, Choi B, Ramirez-San-Juan J, Nelson JS, Kelly KM. Evaluation of vascular effects of photodynamic and photothermal therapies using benzoporphyrin derivative monoacid ring A on a rodent dorsal skinfold model. In: Bartels KE, Bass LS, de Riese WT, Gregory KW, Hirschberg H, Katzir A, Kollias N, Madsen SJ, Malek RS., McNally-Heintzelman KM, Tate LP Jr., Trowers EA, Wong BJF, eds. Photonic Therapeutics and Diagnostics. Bellingham, Wash: International Society for Optical Engineering; 2005:14-21.

29. Ramirez-San-Juan JC, Aguilar G, Tuqan AT, Kelly KM, Nelson JS. Evaluation of sub-zero and residence times after continuous versus multiple intermittent cryogen spray cooling exposure on human skin phantom in Proceedings of 2004 ASME International Mechanical Engineering Conference and Exposition (IMECE), November 13-19, 2004, Aneheim, CA, CD-ROM, Paper IMECE 2004-59635, ISBN: 0-7918-4178-2.

30. Ramirez-San-Juan JC, Aguilar G, Tuqan AT, Kelly KM, Nelson JS. Skin model surface temperature during single and multiple cryogen spurts used in laser dermatologic surgery. Lasers in Surgery and Medicine 2005: 36:141-146.

31. Sun F, Wang GX, Kelly KM, Aguilar G. A Numerical Model for Tissue Freezing in Cutaneous Cryosurgery using Liquid Nitrogen Spray in Proceedings of 5th Int. Symposium on Multiphase Flow, Heat Mass Transfer and Energy, Xi'an Jiaotong University, China, July 2005, ISBN 7-900661-48-4/Z.

32. Tuqan AT, Kelly KM, Aguilar G, Ramirez-San-Juan JC, Sun C-H, Cassarino D, Derienzo D, Barr RJ, Nelson JS. Evaluation of single versus multiple cryogen spray cooling spurts on in vitro model human skin. Lasers Med Sci 2005;20:80-6.

33. Kelly KM, Choi B, McFarlane S, Motosue A, Jung B, Khan MH, Ramirez-San-Juan J.C., Nelson JS. Description and analysis of treatments for port wine stain birthmarks. Arch Facial Plas Surg 2005;7:287-294.

34. Sun F, Wang GX, Kelly KM, Aguilar G. “Numerical modeling of the tissue freeze-thaw cycle during cutaneous cryosurgery using liquid nitrogen spray”, Proceedings of 2005 ASME-IMECE, November 5-11, 2005, Orlando, FL. Paper IMECE2005-82859.

35. Meshkinpour A, Ghasri P, Pope K, Lyubovitsky JL, Risteli J, Krasieva TB, Kelly KM. Treatment of hypertrophic scars and keloids with a radiofrequency device: A study of collagen effects. Lasers Surg Med 2005;37:343-349.

36. Jung B, Kim C-S, Choi B, Kelly KM, Nelson JS. Use of erythema index imaging for systematic analysis of port wine stain skin response to laser therapy. Lasers Surg Med 2005; 37:186-191.

37. Smith TK, Choi B, Ramirez-San-Juan J, Nelson JS, Osann K, Kelly KM. Microvascular blood flow dynamics associated with photodynamic therapy, pulsed dye laser irradiation and combined regimens. Lasers Surg Med 2006 Apr 13;38(5):532-539.

38. Datrice N, Ramirez-San-Juan J, Zhang R, Mehskinpour A, Aguilar G, Nelson JS, Kelly KM. Cutaneous Effects of Cryogen Spray Cooling on In Vivo Human Skin. Dermatologic Surgery 2006 ; 32:009-1014.

39. Zhong R, Ramirez-San-Juan JC. Choi B, Jia W, Aguilar G, Kelly KM, Nelson JS. Thermal response of ex vivo human skin during multiple cryogen spurts and 1,450 nm laser pulses. Lasers Surg Med 2006 Feb;38(2):137-41.

40. McCullough JL. and Kelly KM. Prevention and Treatment of Skin Aging. Annals NY Acad Sci 2006; 1067:323-331.

41. Sun F, Wang GX, Kelly KM, Aguilar G. “Thermal Analysis for Cryosurgery of Nodular Basal Cell Carcinoma”, Proceedings of 2006 ASME-IMECE.

42. Waller JM, Wu JJ, Murase JE, Dyson SW, Kelly KM. Chronically painful right thumb with pustules and onycholysis. Clinical and Experimental Dermatology 2007; 32(5) 619-620.

43. Choi B, Jia W, Channual J, Kelly KM, Lotfi J. The importance of long term monitoring to evaluate the microvasculature response to light-based therapies. J Invest Derm 2008; 128 (2), 455-458.

44. Kelly KM. Current treatment options for port wine stain birthmarks. Photodiag and Photodynamic Ther 2007; 4, 147—148.

45. Channual J, Choi B, Osann K, Pattanachinda D, Lotfi J, Kelly KM. Vascular effects of photodynamic and pulsed dye laser therapy protocols. Lasers Surg Med 2008 Nov;40(9):644-50.

46. Wu J, Papajohn N, Murase JE, Verkruysse W, Kelly KM. Generalized chrysiasis improved with pulsed dye laser. Dermatol Surg. 2009 Mar;35(3):538-42.

47. Rahman Z, Tanner H, Ziang K, Chan KF, Kelly KM, Tournas J, Stumpp OF, Bedi V, Zachary C. Fractional Deep Dermal Ablation Induces Tissue Tightening. Lasers Surg Med 2009.

48. Grant AM, Sry K, Saager R, Ayers F, Pfefer TJ, Kelly KM, Tseng S-H, Durkin AJ. Diffuse Optical spectroscopy of melanoma-simulating silicone phantoms. Proc. SPIE 7187, 718702; 2009.

49. Ayers F, Cuccia D, Kelly KM, Durkin AJ. Wide-field spatial mapping of in vivo tattoo skin optical properties using modulated imaging. Lasers Surg Med 2009 41:442-453.

50. Huang Y-C, Tran N, Shumaker PR, Kelly KM, Ross EV, Nelson JS, Choi B. Blood flow dynamics after laser therapy of port wine stain birthmarks. Lasers Surg Med. 2009;41(8):563-71. PMID: 19731304

51. Nguyen A, Hoang V, Laquer V, Kelly KM. Angiogenesis in Cutaneous Disease Part II. J Am Acad Dermatol. 2009 Dec;61(6):945-958.PMID: 19925925

52. Laquer V, Hoang V, Ngyuen A, Kelly KM. Angiogenesis in Cutaneous Disease Part I. J Am Acad Dermatol. 2009 Dec;61(6):921-942.PMID: 19925924

53. Tournas JA, Lai J, Truitt Anne, Huang YC, Osann KE, Choi B, Kelly KM. Combined benzoporphyrin derivative monoacid ring A photodynamic therapy and pulsed dye laser for port wine stain birthmarks. Photodiag Photodynamic Ther. 2009; 6:195-199.

54. Laquer V, Saedi N, Dann F, Kelly KM. Sorafenib-associated psoriatic skin changes. Cutis. 2010 85:301-2.

55. Kelly KM. Laser Hair Removal: Progress Marches On. Derm Surg. 2010;

56. Fife D, Rayhan DJ, Behnam S, Ortiz A, Elkeeb L, Auino L, Roa DE, Ramsinghani N, Kuo J, Newcomb R, Zachary CB, Kelly KM. A randomized, controlled, double-blinded study of light emitting diode (LED) photomodulation for the prevention of radiation dermatitis in breast cancer patients. Derm Surg 2010; 36: 1-7.

57. Moy AJ, White MS, Indrawan ES, Lotfi J; Nudelman MJ; Costantini SJ; Agarwal N; Jia W, Kelly KM, Sorg BS, Choi B. Wide-field Functional Imaging of Blood Flow and Hemoglobin Oxygen Saturation in the Rodent Dorsal Window Chamber. Microvascular Research 2011; 82:199-209.

58. Kosari P, Kelly KM. Asymptomatic lower lip hyperpigmentation from Laugier-Hunziker Syndrome. Cutis 2011; 88:235-236.

59. Saager R, Cuccia D, Saggese S, Kelly KM, Durkin AJ. Quantitative fluorescence imaging of Protoporphyrin IX though determination of tissue optical properties in the Spatial Frequency Domain. J. Biomed. Opt. 16, 126013 (2011), DOI:10.1117/1.3665440.

60. Nguyen JQM, Saager R, Cuccia DJ, Kelly KM, Hsiang D, and Durkin AJ. Effects of Motion on Optical Properties in the Spatial Frequency Domain, J Biomed Optics. 16, 126009 (2011), DOI:10.1117/1.3662454.

61. Moy WJ, Patel SJ, Lertsakdadet BS, Arora RP, Nielsen KM, Kelly KM, Choi B. Pre-clinical in vivo evaluation of nPe-6 mediated photodynamic therapy on normal vasculature. Laser Surg Med 2012; 44:158-162.

62. Aguilar G, Choi B, Broekgaarden M, Yang O, Yang B, Ghasri P, Chen J, Bezemer R, Nelson JS, van Drroge AM, Wolkerstorfer A, Kelly KM, Heger M. An overview of three promising mechanical, optical, and biochemical engineering approaches to improve selective photothermolysis of resistant port wine stains. Ann Biomed Eng. 2012 Feb;40(2):486-506.

63. Tremaine AM, Armstrong J, Huang Y-C, Elkeeb L, Ortiz A, Harris R, Choi B, Kelly KM. Enhanced port wine stain lightening achieved with combined treatment of selective photothermolysis and imiquimod. J Am Acad Dermatol. 2012 Apr;66(4):634-41.

64. Laquer VT, Dao BM, Pavlis JM, Nguyen AN, Chen TS, Harris RM, Rugg EL, Kelly KM. Immunohistochemistry of angiogenesis mediators before and after pulsed dye laser treatment of angiomas. Lasers Surg Med. 2012 Mar;44(3):205-10. doi: 10.1002/lsm.22005.

65. Truitt A, Elkeeb L, Ortiz A, Saedi N, Echague A, Kelly KM. Evaluation of a long pulsed 1064-nm Nd:YAG laser for improvement in appearance of cellulite. J Cosmet Laser Ther. 2012 Jun;14(3):139-44.

66. Chen JK, Ghasri P, Aguilar G, van Drooge M, Wolkerstorfer A, Kelly KM, Heger M. An overview of clinical and experimental treatment modalities for port wine stains. J Amer Acad Dermatol 2012 67(2): 289-304. PM22305042.

67. Patel AM, Chou EL, Findeiss L, Kelly KM. The Horizon for Treating Cutaneous Vascular Lesions. Seminars in Cutaneous Medicine and Surgery 2012 31(2) 98-104.

68. Sharif SA, Taydas E, Mazhar A, Rahimian R, Kelly KM, Choi B, Durkin AJ. Noninvasive clinical assessment of port-wine stain birthmarks using current and future optical imaging technology: a review. Br J Dermatol. 2012 Dec., 167(6):1215-23. PMID: 22804872

69. Mazhar A, Sharif SA, Nelson JS, Kelly KM, Choi B, Durkin AJ. Spatial frequency domain imaging of port wine stain biochemical composition lesions in response to laser therapy: A pilot study. Lasers Surg Med 2012 Aug 44(8): 611-21. PMID: 22911574

70. Sun F, Martínez-Suástegui L, Wang G-X, Kelly KM, Aguilar G. Numerical prediction of the intracellular ice formation zone during cryosurgery on a nodular basal cell carcinoma using liquid nitrogen spray. Int J Spray Combustion Dynamics 2012 4(4) 341-380.

71. Saager R, Hassan K, Durkin AJ, Kelly KM. Quantitative Near Infrared Spectroscopic Analysis of Q-switched Nd:YAG Treatment of Generalized Argyria. Lasers Surg Med. 2013 Jan;45(1):15-21. PMID: 23322674

72. Laquer V, Hevezi PA, Albrecht H, Chen TS, Zlotnik A, Kelly KM. Microarray Analysis of Port Wine Stains Before and After Pulsed Dye Laser Treatment. Lasers Surg Med. 2013 Feb;45(2):67-75. PMID: 23440713

73. Balu M, Kelly KM, Zachary C, Harris RM, Krasieva TB, Konik K, Tromberg BJ; Clinical studies of pigmented lesions in human skin by using a multiphoton tomograph Proc. SPIE 8588, Multiphoton Microscopy in the Biomedical Sciences XIII, 858812.

74. Saager RB, Cuccia DJ, Saggese S, Kelly KM, Durkin AJ. A Light Emitting Diode Based Spatial Frequency Domain Imaging System for Optimization of Photodynamic Therapy of Nonmelanoma Skin Cancer: Quantitative Reflectance Imaging. Lasers Surg Med. 2013;45:207-215. PMID: 23619900

75. Li D, Wang GX, He YL, Kelly KM, Wu WJ, Wang YX, Ying ZX. A Two-Temperature Model for Selective Thermolysis Laser Treatment of Port Wine Stains. Applied Thermal Engineering 2013;59:41-51. PMID: 25110458

76. Balu M, Kelly KM, Zachary C, Harris R, Krasieva T, Koenig K, Tromberg B. Distinguishing between benign and malignant melanocytic nevi by in vivo multiphoton microscopy. Cancer Research; 2014 May:74(10); 2688–97. PMID: 24686168

77. Ortiz AE, Truong S, Serowka K, Kelly KM. 1320 nm Laser to Improve the Appearance of Onychomycosis. Dermatol Surg. 2014 Dec; 40(12):1356-60. PMID: 25357174

78. Kelly KM, Moy WJ, Moy AJ, Lertsakdadet BS, Moy JJ, Nguyen E, Nguyen A, Osann KE, Choi B. Talaporfin sodium-mediated photodynamic therapy alone and in combination with pulsed dye laser on cutaneous vasculature. J Invest Dermatol. 2015 Jan;135(1):302-4. PMID: 25036051

79. Li D, Farshidi D, Wang GX, HE YL, Kelly KM, Wu WJ, Chen B, Ying ZX. A Comparison of Microvascular Responses to Visible and Near-Infrared Lasers. Lasers Surg Med. 2014 Aug;46(6):479-87. PMID: 24974953

80. Balu M, Zachary CB, Harris RM, Krasieva TB, Konig K, Tromberg BT, Kelly KM. In vivo multiphoton microscopy of basal cell carcinoma. JAMA Dermatol. 2015 Oct;151(10):1068-74. PMID: 25909650.

81. Saager RB, Balu M, Crosignanci V, Sharif A, Durkin AJ, Kelly KM, Tromberg BJ. In Vivo Measurements of Cutaneous melanin across spatial scales using combined Multiphoton Microscopy and Spatial Frequency Domain Spectroscopy. J Biomed Optics 2015 Jun;20(6):066005. PMID: 26065839.

82. Yang B, Yang O, Guzman J, Nguyen P, Crouzet C, Osann KE, Kelly KM, Nelson JS, Choi B. Intraoperative, real-time monitoring of blood flow dynamics associated with laser surgery of port wine stain birthmarks. Lasers Surg Med 2015 Aug;47(6):469-75. PMID: 26040983

83. Moy W, Yakel JD, Osorio C, Salvador J, Hayakawa C, Kelly KM, Choi, B. Targeted narrowband intense pulsed light on cutaneous vasculature. Lasers Surg Med 2015; 47:651-657. PMID: 26227344.

84. Choi B, Tan W, Jia W, White SM, Moy W, Yang B, Zhu J, Chen Z, Kelly KM, Nelson JS. The role of laser speckle imaging in port-wine stain research: Recent advances and opportunities. IEEE J Sel Top Quantum Electron. 2016 May-Jun 2016 (3). PMID: 27013846.

85. Vasefi F, MacKinnon N, Saager R, Kelly KM, Maly T, Chave R, Booth N, Durkin AJ. Farksas DL. Multimode optical dermsocopy (SkinSpect) analysis for skin with melanocytic nevus. Proc SPIE 2016; 9711.

86. Nguyen J, Korta DZ, Chapman L, Kelly KM. Laser treatment of non-genital verrucae. JAMA Dermatol. Published online April 27, 2016. PMID: 27119270

87. Saager R, Sharif A, Kelly KM, Durkin AJ. In vivo isolation of the effects of melanin from underlying hemodynamics across skin types using Spatial Frequency Domain Spectroscopy (SFDS). J. Biomed. Opt. 21(5), 057001 (2016). PMID: 27143641

88. Choi B, Moy W, Ma G, Kelly KM. Hemoporfin mediated photodynamic therapy on normal vasculature: Implications for phototherapy of port wine stain birthmarks. Journal of Clinical and Translational Res. 2016 Sep;2(3):107-111. PMID:29226252

89. Pouli D, Balu M, Alonzo CA, Liu Z, Quinn KP, Rius-Diaz F, Harris RM, Kelly KM, Tromberg BJ, Georgakoudi I. In vivo, label-free assessment of mitochondrial dynamics in human skin reveals depth-dependent hypoxia and malignant potential. Sci Transl Med. 2016 Nov 30;8(367):367ra169. PMID: 27903865.

90. Vasefi F, MacKinnon N, Saager R, Kelly KM, Maly T, Booth N, Durkin A, Farkas DL. Separation of melanin from hemodynamics in nevi using multimode hyperspectral dermoscopy and spatial frequency domain spectroscopy. J Biomed Opt. 2016 Nov 1;21(11):114001. PMID: 27830262 PMCID: PMC5103103.

91. Amber KT, Panganiban C, Korta D, de Feraudy S, Kelly KM, Grando SA. A case report of bullous pemphigoid associated with melanoma and a review of literature. Melanoma Res. 2017 Feb;27(1):65-67. PMID: 27759577

92. Lentsch G, Balu M, Korta D, Koenig K, Kelly KM, Tromberg B, Zachary C. In vivo multiphoton-microscopy of picosecond-laser-induced optical breakdown in human skin. Lasers Surg Med 2017 March; 49(2). PMID:28333369

93. Hagen SL, Grey KR, Korta DZ, Kelly KM. Quality of life in adults with facial port-wine stains. J Am Acad Dermatol. 2017 Apr;76(4):695-702. PMID: 27955934

94. Moy WJ, Yao J, De Feraudy SM, White SM, Salvador J, Kelly KM, Choi B. Histologic changes associated with talaporfin sodium-mediated photodynamic therapy in rat skin. Lasers Surg Med 2017, May; PMID:28489260

95. Soleymani Teo, Abrouk M, Kelly KM. An analysis of laser therapy for the treatment of non-melanoma skin cancer. Dermatol Surg. 2017 May;43(5):615-624. PMID:28195845

96. Brodsky M, Abrouk M, Lee P, Kelly KM. Revisiting the history and importance of phototherapy in dermatology. JAMA Dermatol. 2017;153(5):435. PMID:28492838

97. Spring LK, Krakowski AC, Alam M, Bhatia A, Brauer J, Cohen J, Del Rosso J, Diaz L, Dover J, Eichenfield LF, Gurner GC, Hanke W, Jahnke MN, Kelly KM, Khetarpal S, Kinney MA, Levy ML, Leyden J, Longaker MT, Munavalli, GS, Ozog, DM, Prather H, Shumaker PR, Tanzi E, Torres A, Velez MW, Waldman AB, Yan AC, Zaenglein AL. Isotretinoin and the Timing of Procedural Interventions: A Systematic Review with Consensus Recommendations. JAMA Derm 2017;153(8):802-809. PMID:28658462

98. Valdebran M. Martin B, Kelly KM. State of the art lasers and light sources for treatment of vascular lesions: from red face to vascular malformations. Semin Cutan Med Surg. 2017 Dec;36(4):207-212. PMID:29224039

99. Saager, RB, Dang AN, Huang SS, Kelly KM, Durkin AJ. Handheld spatial frequency domain spectrographic imager for depth-sensitive, quantitative spectroscopy of skin tissue. Proceedings of SPIE Vol. 10037; Photonics in Dermatology and Plastic Surgery.

100. Amber KT, Valdebran M, Makdisi J, De Feraudy S, Balu M, Kelly KM. A case of photodistributed multicentric reticulohistiocytosis: Correlation with multiphoton microscopy imaging. J der Deutschen Dermatologischen Gesellschaft. 2018.

101. Waibel J, Homes J, Rudnick A, Woods D, Kelly KM. Angiographic optical coherence tomography imaging of hemangiomas and port wine birthmarks. Lasers Surgery Medicine 2018. PMID: 29566276.

102. Saager RB, Baldado M, Rowland R, Kelly KM, Durkin AJ. Methods using in vivo quantitative spectroscopy to guide design and optimization of low-cost, compact clinical imaging devices: emulation and evaluation of multispectral imaging systems. J Biomed Opt. 2018 Apr;23(4):1-12. PMID: 29633609

103. Laquer V, Dellinger RWm Mannering I, Garcia AG, Abraham V, Pavlis J, Liu-Smit F, De Feraudy S, Meysekens FL, Kelly KM. 12-hydroxyeicosatetraenoic acid (12-HETE) is elevated in Actinic Keratoses (AK) and Squamous Cell Carcinoma (SCC). J Am Acad Dermatol. 2018. 79 (6):1152-1153. PMID: 29902547

104. Kelly KM. Science and Peace. Lasers Surg Med. 2019. PMID:30561812

105. Gelfand JA, Brauns T, Kimizuka Y, Korek S, Botvinick E, Elkins K, Thomas K, Locascio J, Parry B, Kelly KM, Poznansky MC. A pilot clinical trial of a near-infrared laser vaccine adjuvant: safety, tolerability, and cutaneous immune cell trafficking. FASEB J. 2018. 33(2):3074-3081. PMID 30192655; PMCID: PMC6338655

106. White S, Valdebran M, Kelly KM, Choi B. Simultaneous Blood Flow Measurement and Dermoscopy of Skin Lesions Using Dual-Mode Dermascope. Sci Rep. 2018 Nov 16;8(1):16941. PMID: 30446685

107. Hosking A-M, Coakley BJ, Chang D, Talebi-Liasi F, Lish S, Lee SW, ZOng A, Moore I, Browning J, Jacques SL. Krueger J, Kelly KM, Linden KG, Gareau DS. Hyperspectral Imaging in Automated Digital Dermoscopy Screening for Melanoma. Lasers Surg med. 2019: 51:214-222. PMID: 30653684

108. Kelly A, Pai A, Lertsaksadet B, Choi B, Kelly KM. Microvacular effects of oxymetazoline in combination with pulsed dye laser. Lasers Surg Med. 2020; 52:17-22. PMID 31758568.

109. Antiquera P, Abi-Jaodeh N, Nelson JS, Kelly KM, Nelson K. Effect of long-term phosphodiesterase-5 inhibitor use on refractory lymphatic malformations in adult and teen patients. Journal of Vascular Surg Venous Lymphat Disord. Accepted for publication. 2020. PMID: 32305583

110. Lentsch G, Valdebran M, Saknite I, Smith J, Linden KG, Konig K, Barr RJ, Harri RM, Tromberg BJ, Ganesan AK, Zachary CB, Kelly KM, Balu M. Non-invasive optical biopsy by multiphoton microscopy identifies the live morphology of common melanocytic nevi. Pigment Cell Melanoma Res. 2020. PMID 32485062.
Corresponding Author.

111. Fransen F, Spuls P, ALam M,Badawi A, Boxieda P, Haedersdal M, Hamzavi I, Hedelund L, Kelly KM, Kono T, Laubach HJ, Manusciatti W, Marini L, Nouri K, Paasch U, Passeron T, Sanna Prinsen CAC, Verner I, Wolkerstorfer A. Generic outcome set for the international registry on Laser trEAtments in Dermatology (LEAD): a protocol for a Delphi study to achieve consensus on what to measure. BMJ Open, 2020. PMID 32595165

112. Valdebran M, Elbendary A, Choi F, Kittle H, Kelly KM. Dermascopic features of infantile hemangioma during treatment with topical propranolol. JAAD International 2020 1(2) 121-123.

113. Sabeti S, Kelly KM, Burkhart C. Lasers, Birthmarks, and Sturge-Weber Syndrome: A Pilot Survey. Accepted to LSM 9.2020.

114. Sara Sabeti, BS; Karen L Ball, BS; Craig Burkhart, MS, MPH, MD; Lawrence Eichenfield, MD; Esteban Fernandez Faith, MD; Ilona J. Frieden, MD; Roy Geronemus, MD7 Deepti Gupta, MD; Andrew C. Krakowski, MD; Moise L. Levy, MD; Denise Metry, MD, J. Stuart Nelson, MD, PhD; Megha M. Tollefson, MD; Kristen M. Kelly, MD. Consensus Statement for the Management of Sturge Weber Syndrome: Dermatology Recommendations. Accepted to JAMA Derm. 9.2020.

115. Mehrabi JN, Fast A, Lentsch G, Balu M, Kelly KM. A clinical perspective on the automated analysis of reflectance confocal microscopy in dermatology, a systematic review. Submitted to LSM 2020.

116. Tran J, Arkin L, Krakowski A, Kelly KM, Drolet B. Light-based Treatment of Pediatric Port-wine Birthmarks (PWBs)" has been successfully submitted online to Pediatric Dermatology. Submitted to Pediatric Dermatology 2020.

117. Snyder A, Valdebran M, Terrerro D, Amber KT, Kelly KM. Solar Ultraviolet Exposure in Individuals who Perform Outdoor Sports Activities. Accepted for publication in Sport Medicine-Open. 2020.

Book Chapters:
1. Cesario, K., Yousefi, S., Carandang, G., Cesario, T.C. Mycobacterial Disease in the AIDS Patient in Surgical Problems in the AIDS Patient, Igaku-Shoin, New York, New York.

2. Kelly, K.M., Weinstein, G. Book Chapter: Update on Drugs Used in the Treatment of Psoriasis in Dermatologic Therapy in Current Practice, Eds: R. Marks, J.J. Leyden. Martin Dunitz Limited, London 2002.

3. Mcullough, J.L., Kelly, K.M. Prevention and Treatment of Skin Aging in Aging Interventions and Therapies, Ed: Suresh Rattan. World Scientific Publishers, Singapore, 2004.

4. Kelly, K.M., Welch, E. Other Dermatologic Indications for Aminolevulinic Acid Photodynamic Therapy in Procedures In Cosmetic Dermatology Series: Aminolevulinic Acid Photodynamic Therapy in Cosmetic and Medical Dermatology, Ed: Mitchell Goldman. Martin Mellor Publishing Service Limited, Edinborough, 2004.

5. Kelly, K.M., Nelson, J.S. Skin Cooling in Laser Dermatology. 2005.

6. Jung, M.S., Kelly, K.M., McCullough, J.L. Skin Aging: Pathogenesis, Prevention and Treatment in Prevention and Treatment of Age-related Diseases, Eds: Suresh Rattan and Moustapha Kassem. Springer Publishers, The Netherlands/USA/UK, 2005.

7. Smith TK, Choi B, Ramirez-San-Juan J, Nelson JS, Kelly KM. Evaluation of vascular effects of photodynamic and photothermal therapies using benzoporphyrin derivative monoacid ring A on a rodent dorsal skinfold model. In: Bartels KE, Bass LS, de Riese WT, Gregory KW, Hirschberg H, Katzir A, Kollias N, Madsen SJ, Malek RS., McNally-Heintzelman KM, Tate LP Jr., Trowers EA, Wong BJF, eds. Photonic Therapeutics and Diagnostics. Bellingham, Wash: International Society for Optical Engineering; 2005:14-21.

8. Kormeili T and Kelly KM. Treatment of cutaneous T cell lymphoma, psoriasis and port wine stain birthmarks in Procedures in Cosmetic Dermatology Series: Photodynamic Therapy. Second Edition, Ed: Goldman, MP. Saunders. 2007.

9. Vallee JA, Kelly KM, Rohrer TE, Arndt KA, Dover JS. Lasers in the treatment of vascular lesions in Atlas of Cosmetic Surgery, Ed: Kaminer MS, Arndt KA, Dover JS, Rohrer TE and Zachary CB. Saunders, Philadelphia, PA, 2009.

10. Kelly KM. Lasers and Light Therapy for Cutaneous Vascular Lesions published on Up to Date, Section Editor: JS Dover, Deputy Editor AO Ofori. 2/2011.

11. Rubin IK, Kelly KM. Lasers and Light Treatments for Cutaneous Vascular Lesions in Lasers and Lights - Procedures in Cosmetic Dermatology Series, Ed; Avram MM and Hruza GJ. Elsevier, London, 2012.

12. Serowka K, Kelly KM. Vascular Lesions in Procedural Dermatology, Ed: Avram M, Avram M and Ratner D. McGraw Hill, Burr Ridge, Il, 2014.

13. Cheng N, Rubin IK, Kelly KM. Laser Treatment of Vascular Lesions in Lasers and Lights - Procedures in Cosmetic Dermatology, Ed: Tanzi E, Hruza GJ, Dover J and Alam M. Elsevier, London, 2017.

14. Chapman L and Kelly KM. Port Wine Birthmarks in Cosmetic Dermatologic Surgery. Ed: Macrene Alexiades-Armenakas. Wolters Kluwers, Philadelphia, PA, 2017 (pending).

15. Zachary C, Kelly KM. Lasers and Other Energy Based Therapies in Dermatology in Dermatology. Ed: Bolognia, Shaffer and Cerroni. Elsevier, London, 2017.

16. Balu M, Kelly KM, Harris RM, Koenig K, Zachary CB, Tromberg BJ. "Chapter 15: In vivo multiphoton microscopy of human skin," in Multiphoton Microscopy and Fluorescence Lifetime Imaging, Applications in Biology and Medicine, 1 ed., Editor: K. Koenig. de Gruyter, 2018, pp. 75-87 (pending).

17. Lehmer L, Kelly KM. Introduction to Lasers in Pediatric Procedural Dermatology. Ed: Andrew Krakowski. Wolters Kluwers. 2020.

18. Lehmer L, Kelly KM. Laser Treatment of Vascular Lesions in Pediatric Procedural Dermatology. Ed: Andrew Krakowski. Wolters Kluwers. 2020.

19. Krakowski A, Munavelli G, Kelly KM and Uebelhoer N. Angiofibromas associated with Tuberous Sclerosis in Pediatric Procedural Dermatology. Ed: Andrew Krakowski. Wolters Kluwers. 2020.
1/05-1/06 Sturge-Weber Foundation Grant Project Title: Photodynamic Treatment of Port Wine Stains
7/04-3/08 NIH R03 Project Title: Photodynamic and Photothermal treatment of Port Wine Stain
6/02-6/05 Dermatology Foundation Clinical Career Development Award Project Title: Optimizing Laser Treatment of Port Wine Stain Using Cryogen Spray Cooling
10/01-10/03 A.Ward Ford Grant – American Society for Laser Medicine and Surgery Project Title: Optimizing Laser Treatment of Port Wine Stains Using Cryogen Spray Cooling
6/03-9/04 Thermage Corporation Research Grant Project Title: Treatment of Hypertrophic Scars and Keloids with a Radiofrequency Device
9/06-10/09 Candela Corporation Research Grant Project Title: Evaluation of the Candela 1064 nm Nd:YAG Laser for Treatment of Cellulite and Tightening of Skin
4/06-6/11 3M Research Grant Project Title: Combining Topical Imiquimod with Pulsed Dye Laser for Treatment Port Wine Stain Birthmarks
4/07-4/10 Faculty Sponsor for American Society of Dermatologic Surgery Grant Project Title: LED photomodulation for prevention of post-radiation treatment dermatitis: A prospective, randomized, controlled study
1/07-1/09 Faculty Sponsor for Alpha Omega Alpha Medical Student Service Award Project Title: Skin Cancer Awareness, Education and Detection for Cosmetologists and Allied Health Professionals
6/08-8/08 Faculty Sponsor for Dean’s Summer Research Stipend Project Title: Vascular effects of pulsed dye laser in combination with anti-angiogenic agents
6/08-8/08 Faculty Sponsor for Dean’s Summer Research Stipend Project Title: Investigation of a novel photosensitizer, nanoparticle indocyanine green, for cutaneous photodynamic therapy
Faculty sponsor for medical Student American Heart Association Grant Project Title: Role of Angiogenesis in Dermatologic Diseases: A Potential Therapeutic Target
7/08-9/08 Faculty sponsor for Undergraduate Student Research Opportunities Project Title: Effects of Indocyanine Green in Combination with 755 nm Laser on Mouse Microvasculature
2/08-3/10 Sponsor: US Army Medical Research & Materiel Command Project Title: SEAtreat Cancer Technology / SEAtreat Photodynamic Therapy
7/10-7/11 NIH Shared Instrumentation Grant Project Title: Multiwavelength Diode Laser System
1/11-1/13 UC Irvine Cancer Center Seed Grant Project Title: Regarding Role of Metabolic Enzymes in Skin Cancer: Potential for Informative Biomarkers and Therapeutic Targets
10/11-10/13 Faculty Sponsor for American Society of Dermatologic Surgery Grant Project Title: A Randomized, Placebo-Controlled Study of the 1320 nm Nd:YAG Laser for Treatment of Onychomycosis
7/10-5/16 NIH R01 Project Title: Novel Treatment Approach for Vascular Birthmarks
3/14-3/16 Sturge Weber Foundation Grant Project Title: Vascularized Port Wine Stain Skin Model for Evaluation of Cell
9/14-8/15 Dean’s Triumvirate Grant 2014 Project Title: A Portable, Quantitative Imaging Device for Noninvasive Melanoma Screening/Detection
10/14-2/17 1R44CA183169-01A1 PI: Dan Farkas (SMI Inc), AJ Durkin Subcontract (UCI) NIH/NIBIB Phase 1/Phase 2 SBIR NIH/NCI via Spectral Molecular Imaging Hyperspectral Imaging based Multimode Dermoscope for Early Melanoma Detection
3/16-2/19 NIH R01 1R01CA195466-01A1 Kelly (PI) Project Title: Quantitative multiphoton microscopy for non-invasive diagnosis of melanoma
7/1/17- 6/30/22NIH UG3/UH3HL141799 Hughes (PI) Project Title: Microphysiological systems to model vascular malformation
12/30/2017-10/1/2018 Allergan Kelly (PI) Rodent Dorsal Window Model Study of Pulsed dye laser in combination with oxymetazoline.
06/18-05/21. 1R15CA227946, NIH Ying Huang (PI) Topical delivery of non-ß-blocking R-carvedilol for prevention of UV-induced skin cancer
3/15/2019-3/14/2020 Chao Family Comprehensive Cancer Center Pilot Project Funding Project Title: A Mechanistic Study of Age-Dependent Gender Difference In Melanoma Risk
4/1//2019-3/31/2020 Skin Cancer Pilot Grant Awards Project Title: Imaging and Diagnosis of Skin Cancer Utilizing 1.7 um Doppler Opitcal Coherence Tomography
8/30/2019. Lisa’s Catalyst Grant Project Title: Sturge Weber Consensus Project
9/1/2019. Cancer Research Coordinating Committee Faculty Seed Grant Project Title: Impact of Sex Hormones on Melanoma Development
3/1/2020-2/28/2021 Chao Family Comprehensive Cancer Center Anti-Cancer Challenge Project Title: Pilot study for evaluating the multiphoton microscopy potential for non-invasive, early diagnosis of melanoma
Professional Societies
Fellow American Academy of Dermatology
Fellow American Society for Laser Medicine and Surgery
Member Orange County Dermatologic Society
Member American Society for Photodynamic Therapy
Member International Society for the Study of Vascular Anomalies
Member American Society for Dermatologic Surgery
Member Society for Pediatric Dermatology
Active Member Pediatric Dermatology Research Alliance
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