Daniel Christopher Jaffurs

picture of Daniel Christopher Jaffurs

Associate Clinical Professor, Plastic Surgery
School of Medicine

M.D., University of Pittsburgh, 2000
Ph.D., University of Pittsburgh, 1999, Molecular Genetics

Phone: (714) 456-5253
Fax: (714) 456-7718
Email: djaffurs@uci.edu

University of California, Irvine
Department of Plastic Surgery
200 S. Manchester Ave. Suite 650
Mail Code: 5398
Orange, CA 92868
Research Interests
Craniosynostosis, Wound Healing, Congenital Malformations
Published Refereed Articles:

Mi, Z., S.C Ghivizzani, E.R. Lechman, D. Jaffurs, J.C. Glorioso, C.H. Evans and P.D. Robbins (2000) Adenovirus-mediated gene transfer of insulin-like growth factor 1 stimulates proteoglycan synthesis in rabbit joints. Arthritis & Rheumatism, 43(11):2563-70.

Studer R.K., E. Levicoff, H. Georgescu, L. Miller, D. Jaffurs and C.H. Evans (2000) Nitric oxide inhibits chondrocyte response to IGF-I: inhibition of IGF-IRbeta tyrosine phosphorylation. American Journal of Physiology - Cell Physiology, 279(4):C961-969.

Lechman, E.R., D. Jaffurs, S.C. Ghivizzani, A. Gambotto, I. Kovesdi, Z. Mi, C.H. Evans and P.D. Robbins (1999) Direct adenoviral mediated gene transfer of vIL-10 to rabbit knees with experimental arthritis halts disease progression in both injected and contralateral, noninjected knee joints. Journal of Immunology, 163(4): 2202-2208.

Ghivizzani, S.C., R. Kang, H.I. Georgescu, E.R. Lechman, D. Jaffurs, J.M. Engle, S.C. Watkins, M.H. Tindal, M.K. Suchanek, L.R. McKenzie, C.H. Evans, and P.D. Robbins (1997) Constitutive intra-articular expression of human IL-1 beta following gene transfer to rabbit synovium produces all major pathologies of human rheumatoid arthritis. Journal of Immunology, 159(7):3604-3612.

Gao, X., D. Jaffurs, P.D. Robbins, and L. Huang (1994) A sustained, cytoplasmic transgene expression system delivered by cationic liposomes. Biochemical & Biophysical Research Communications, 200(3):1201-1216.

Watts, S.A., G. Hines, D. Jaffurs, K. Lee, J. Roy, F.F. Smith, and C.W. Walker (1990) Seasonal patterns of ornithine decarboxylase activity and levels of polyamines in relation to the cytology of germinal cells during spermatogenesis in the sea star, Asterias vulgaris. Tissue and Cell, 22:435-447.
Graduate Programs

Plastic Surgery

Craniofacial Surgery (PS)

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