E.Alison Holman

picture of E.Alison  Holman

Professor
Sue & Bill Gross School of Nursing


Ph.D., U.C. Irvine, 1996, Health Psychology
B.A., University of California, Santa Cruz, 1989, Psychology
B.S., San Francisco State University, 1981, Nursing
Family Nurse Practitioner Certification, University of California, Irvine, 2001, Family Medicine

Phone: (949) 824-7016
Fax: (949) 824-0470
Email: aholman@uci.edu

University of California, Irvine
Sue & Bill Gross School of Nursing
252J Berk Hall
Mail Code: 3959
Irvine, CA 92697
Research Interests
Acute stress & cardiovascular disease; genetic vulnerability to stress-related mental/physical health problems; cognitive, social and emotional response to trauma.
Academic Distinctions
Robert Wood Johnson Foundation Nurse Faculty Scholar 2010-2013
Fellow American Academy of Nurses 2018
Fellow Academy of Behavioral Medicine Research 2019
Appointments
Post-doctoral Visiting Scholar, Department of Psychology, Stanford University
1997-1998
Research Abstract
My research focuses on understanding the early post-event predictors of comorbid trauma-related mental and physical health problems. I seek to identify predictors of, contributions of, and interactions between acute responses to trauma (biological, cognitive, emotional, social, environmental, behavioral) that increase vulnerability to trauma-related health problems, especially cardiovascular disease. Toward this end, I examine gene-environment interactions and the roles of several biological systems in acute/posttraumatic stress response: renin-angiotensin-aldosterone, endocannabinoid, and oxytocin systems as well as hypothalamic-pituitary-adrenal axis response. The ultimate goal is to identify targets for early interventions to prevent trauma-related morbidity and mortality.
Publications
61. Holman, E. A., & *Grisham, E. L. (2020). When time falls apart: The public health implications of distorted time perception in the age of COVID-19. Psychological Trauma: Theory, Research, Practice and Policy, 12 (S1), S63-S65.

60. *Thompson, R. R., Holman, E. A., & Silver, R. C. (2020). Worst life events and media exposure to terrorism in a nationally representative U.S. sample. Journal of Traumatic Stress. DOI:10.1002/jts.22534

59. *Thompson, R. R., Garfin, D. R., Holman, E. A., & Silver, R. C. (2020). National opinions on death penalty punishment for the Boston Marathon bomber before versus after sentencing. Psychology, Public Policy, and Law. doi.org/10.1037/law0000244

58. Garfin, D. R., Silver, R. C., & Holman, E. A. (2020). The novel Coronavirus (COVID-19) outbreak: Amplification of public health consequences by media exposure. Health Psychology, 39, 355-357. http://dx.doi.org/10.1037/hea0000875

57. Holman, E. A., *Garfin D. R., *Lubens, P., & Silver, R. C. (2020). Media exposure to collective trauma, mental health, and functioning: Does it matter what you see? Clinical Psychological Science, 8, 111-124. DOI: 10.1177/2167702619858300

56. *Garfin, D. R., Holman, E. A., & Silver, R. C. (2020). Cumulative exposure to prior negative life events and responses to the Boston Marathon bombings. Psychological Trauma: Theory, Research, Practice and Policy, 12, 320-329.

55. *Sweeting, J., *Garfin, D. R., Holman, E. A., & Silver, R. C. (2020). Associations between exposure to childhood bullying and abuse and adulthood outcomes in a representative national U.S. sample. Child Abuse and Neglect, 101, 104048.

54. *Thompson, R. R., *Jones, N. M., Holman, E. A., & Silver, R. C. (2019). Media exposure to mass violence events can fuel a cycle of distress. Science Advances, 5(4), eaav3502.

53. *Redmond, S., *Jones, N. M., Holman, E. A., & Silver, R. C. (2019). Who watches an ISIS beheading – and why. American Psychologist, 74, 555-568. (Published ahead of print February 25, 2019). doi.org/10.1037/amp0000438.

52. *Thompson, R. R., Holman, E. A., & Silver, R. C. (2019). Media coverage, forecasted posttraumatic stress symptoms, and psychological responses before and after an approaching hurricane. JAMA Network Open, 2(1), e186228-e186228.

51. Morrison, C. D., Poulin, M. J., & Holman, E. A. (2018). Gender, genes, and the stress-buffering benefits of “home”: Evidence from two national US studies. Journal of Environmental Psychology, 60, 89-99.

50. *Jose, R., Holman, E. A., Silver, R. C. (2018). Community Organizations and Mental Health after the 2013 Boston Marathon Bombings. Social Science and Medicine, 222, 367-76.

49.*Garfin, D. R., *Thompson, R. R., Holman, E. A. (2018). Acute Psychological Responses to Trauma and Future Health: A Systematic Review. Journal of Psychosomatic Research, 112, 107-113. DOI: https://doi.org/10.1016/j.jpsychores.2018.05.017

48. Fischhoff, B., *Wong-Parodi, G., *Garfin, D. R., Holman, E. A., & Silver, R. C. (2018). Public understanding of Ebola risks: Mastering an unfamiliar threat. Risk Analysis, 38, 71-83.

47. *Juth, V., *Chan, M., Cramer, S. C., Holman, E. A. (2018). Assessing acute psychological distress in the immediate aftermath of stroke. European Journal of Cardiovascular Nursing, 17, 186-189.
DOI: 10.1177/1474515117719809

46. *Jose, R., Holman, E. A., Silver, R. C. (2017). The importance of the neighborhood in the 2014 Ebola outbreak in the United States: Distress, worry, and functioning. Health Psychology, 36, 1181-1185.

45. *Thompson, R. R., *Garfin, D. G., Holman, E. A., Silver, R. C. (2017). Distress, worry, and functioning following a global health crisis: A national study of Americans’ responses to Ebola. Clinical Psychological Science, 5, 517-521.

44. *Jones, N. M., *Garfin, D. R., Holman, E. A., & Silver, R. C. (2016). Media use and exposure to graphic content in the week following the Boston Marathon bombings. American Journal of Community Psychology, 58, 47-59. DOI: 10.1002/ajcp.12073

43. Holman, E. A., Silver, R. C., Mogle, J. A., Scott, S. B. (2016). Adversity, time, and well-being: A longitudinal analysis of time perspective in adulthood. Psychology and Aging, 31, 640-651.

42. *Juth, V., Holman, E. A., *Chan, M., Cramer, S. C. (2016). Genetics as a molecular window into recovery, treatment, and stress responses after stroke. Journal of Investigative Medicine, 64, 983–988. doi:10.1136/jim-2016-000126

41. Holman, E. A. (2015). Psychological distress and susceptibility to cardiovascular disease across the lifespan: Implications for future research and clinical practice. (Invited editorial) Journal of the American College of Cardiology (JACC), 66, 1587-89.

40. *Garfin, D. R., Holman, E. A., Silver, R. C. (2015). Cumulative Exposure to Prior Collective Trauma and Acute Stress Responses to the Boston Marathon Bombings. Psychological Science, 26(6), 675–683.

39. Holman, E. A., *Garfin, D. R., & Silver, R. C. (2014). Media’s role in broadcasting acute stress following the Boston Marathon bombings. Proceedings of the National Academy of Science of the USA, 111, 93-98. doi/10.1073/pnas.1316265110

Abstracted in J. Silver (2014, January 10). Stop replaying the tragedy. NEJM Journal Watch. 2014 (jan10_6) NA33132

38. Holman, E.A., *Guijarro, A., Lim, J., & Piomelli, D. (2014). Effects of acute stress on cardiac endocannabinoids, lipogenesis, and inflammation in rats. Psychosomatic Medicine, 76(1), 20-28.

37. *Lessard, J., & Holman, E. A. (2014). FKBP5 and CRHR1 polymorphisms moderate the effects of child abuse and adult stress on physical health. Health Psychology, 33, 1046-1056.

36. *Lucas-Thompson, R., & Holman, E. A. (2013). Environmental stress, oxytocin receptor gene (OXTR) polymorphism, and mental health following collective stress. Hormones & Behavior, 63, 615-624.

35. Poulin, M. J., & Holman, E. A. (2013). Helping hands, healthy body? Oxytocin receptor gene and prosocial behavior interact to buffer the association between stress and physical health. Hormones & Behavior, 63, 510-517.
 
34. Silver, R. C., Holman, E. A., Andersen, J. P., Poulin, M., McIntosh, D. N., & Gil-Rivas, V. (2013). Mental and physical health effects of acute exposure to media images of the 9/11 attacks and the Iraq War. Psychological Science, 24, 1623-1634.

33. Holman, E. A. (2012). Acute stress and cardiovascular health: Is there an ACE gene connection? Journal of Traumatic Stress, 25, 592-597.

32. Poulin, M. J., Holman, E. A., & Buffone, A. (2012). The neurogenetics of nice: Receptor genes for Oxytocin and Vasopressin interact with threat to predict prosocial behavior. Psychological Science, 23, 446-452.

31. Holman, E. A., *Lucas-Thompson, R. G., & *Lu, T. (2011). Social constraints, genetic vulnerability, and mental health following collective stress. Journal of Traumatic Stress, 24, 497-505.

30. Holman, E. A., & Silver, R. C. (2011). Health status and health care utilization following collective trauma: A 3-year national study of the 9/11 terrorist attacks in the United States. Social Science and Medicine, 73, 483-490.

29. McIntosh, D. N., Poulin, M. J., Silver, R. C., & Holman, E. A. (2011). The distinct roles of spirituality and religiosity in physical and mental health after collective trauma: A national longitudinal study of responses to the 9/11 attacks. Journal of Behavioral Medicine, 34, 497-507.

28. Holman, E. A., *Perisho, J., *Edwards, A., & *Mlakar, N. (2010). The myths of coping with loss in undergraduate psychiatric nursing books. Research in Nursing and Health, 33, 486-499.

27. *Seery, M. D., Holman, E. A., & Silver, R. C. (2010). Whatever does not kill us: Cumulative lifetime adversity, vulnerability, and resilience. Journal of Personality and Social Psychology, 99, 1025-1041.

26. *Seery, M. D., Leo, R. J., Holman, E. A., & Silver, R. C. (2010). Lifetime exposure to adversity predicts functional impairment and healthcare utilization among individuals with chronic back pain. Pain, 150, 507-515.

25. Holman, E. A., & Zimbardo, P. G. (2009). The social language of time: The time perspective-social network connection. Basic and Applied Social Psychology, 31, 136-147.

24. Poulin, M. J., Silver, R. C., Gil-Rivas, V., Holman, E. A., & McIntosh, D. N. (2009). Finding social benefits after a collective trauma: Perceiving societal changes and well-being following 9/11. Journal of Traumatic Stress, 22, 81-90.

23. Holman, E. A., Silver, R. C., *Poulin, M., *Andersen, J., *Gil-Rivas, V., & McIntosh, D. N. (2008). Terrorism, acute stress, and cardiovascular health: A 3-year national study following the September 11th attacks. Archives of General Psychiatry, 65, 73-80. doi: 10.1001/archgenpsychiatry.2007.6

22. *Seery, M. D., Silver R. C., Holman, E. A., Ence, W. A., & Chu, T. Q. (2008). Expressing thoughts and feelings following a collective trauma: Immediate responses to 9/11 predict negative outcomes in a national sample. Journal of Consulting and Clinical Psychology, 76, 657-667. DOI: 10.1037/0022-006X.76.4.657

21. Suvak, M., Maguen, S., Litz, B. T., Silver R. C., & Holman, E. A. (2008). Indirect exposure to the September 11 terrorist attacks: Does symptom structure resemble PTSD? Journal of Traumatic Stress, 21, 30-39.

20. *Updegraff, J. A., Silver, R. C., & Holman, E. A. (2008). Searching for and finding meaning in collective trauma: Results from a national longitudinal study of the 9/11 terrorist attacks. Journal of Personality and Social Psychology, 95, 709-722. doi: 10.1037/0022-3514.95.3.709

19. *Gil-Rivas, V., Silver, R. C., Holman, E. A., McIntosh, D. N., & *Poulin, M. (2007). Parental response and adolescent adjustment to the September 11, 2001 terrorist attacks. Journal of Traumatic Stress, 20, 1063-1068.

18. Chu, T. Q., *Seery, M. D., Ence, W. A., Holman, E. A., & Silver, R. C. (2006). Ethnicity and gender in the face of a terrorist attack: A national longitudinal study of immediate responses and outcomes two years after September 11. Basic and Applied Social Psychology, 28, 291-301.

17. Holman, E. A., & Silver R. C. (2005). Future-oriented thinking and adjustment in a nationwide longitudinal study following the September 11th terrorist attacks. Motivation and Emotion, 29, 389-410.

16. *Gil-Rivas, V., Holman, E. A., & Silver, R.C. (2004). Adolescent vulnerability following the September 11th terrorist attacks: A study of parents and their children. Applied Developmental Science, 8, 130-142.

15. Hawkins, N. A., McIntosh, D. N., Silver, R. C., & Holman, E. A. (2004). Early responses to school violence: A qualitative analysis of students' and parents' immediate reactions to the shootings at Columbine High School. Journal of Emotional Abuse, 4, 197-223.

Also appears in R. Geffner, M. Braverman, J. Galasso, & J. Marsh (Eds.), Aggression in organizations: Violence, abuse, and harassment at work and in schools (pp. 197-223). Binghamton, NY: Haworth Press, 2004.

14. Silver, R. C., *Poulin, M., Holman, E. A., McIntosh, D. N., *Gil-Rivas, V., & *Pizarro, J. (2004). Exploring the myths of coping with a national trauma: A longitudinal study of responses to the September 11th terrorist attacks. Journal of Aggression, Maltreatment & Trauma, 9, 129-141.

Also appears in Y. Danieli, D. Brom, & J. Sills (Eds.), The trauma of terrorism: Sharing knowledge and shared care, An international handbook (pp. 129-141). Binghamton, NY: Haworth Press, 2005.

13. Silver, R. C., Holman, E. A., McIntosh, D. N., *Poulin, M., & *Gil-Rivas, V. (2002). Nationwide longitudinal study of psychological responses to September 11. JAMA: The Journal of the American Medical Association, 288, 1235-1244. doi:10.1001/jama.288.10.1235

12. Holman, E. A., Silver, R. C., & Waitzkin, H. (2000). Traumatic life events in primary care patients: A study in an ethnically-diverse sample. Archives of Family Medicine, 9, 802-810.

11. Escobar, J. I., Gara, M., Silver, R. C., Waitzkin, H., Holman, E. A., & Compton, W. (1998). Somatisation Disorder in primary care. The British Journal of Psychiatry, 173, 262-266.

10. Escobar, J. I., Gara, M., Waitzkin, H., Silver, R. C., Holman, E. A., & Compton, W. (1998). DSM-IV Hypochondriasis in primary care. General Hospital Psychiatry, 20, 155-159.

9. Escobar, J. I., Waitzkin, H., Silver, R. C., Gara, M., & Holman, E. A. (1998). Abridged somatization: A study in primary care. Psychosomatic Medicine, 60, 466-472.

8. Gara, M., Silver, R. C., Escobar, J. I., Holman, E. A., & Waitzkin, H. (1998). A hierarchical classes analysis (HICLAS) of primary care patients with medically unexplained somatic symptoms. Psychiatry Research, 81, 77-86.

7. Holman, E. A., & Silver, R. C. (1998). Getting “stuck” in the past: Temporal orientation and coping with trauma. Journal of Personality and Social Psychology, 74, 1146-1163.

6. Holman, E. A. (1997). The nursing profession’s role in health psychology research: A reply to Helgeson and Lepore. The Health Psychologist, 19, 8.

5. Holman, E. A., & Silver, R. C. (1996). Is it the abuse or the aftermath? A stress and coping approach to understanding responses to incest. Journal of Social and Clinical Psychology, 15, 318-339.

4. Holman, E. A., & Stokols, D. (1994). The environmental psychology of child sexual abuse. Journal of Environmental Psychology, 14, 237-252.

3. Whalen, C. K., Henker, B., O'Neil, R., Hollingshead, J., Holman, E. A., & Moore, B. (1994). Optimism in children's judgments of health and environmental risks. Health Psychology, 13, 319-325.

2. Whalen, C. K., Henker, B., O'Neil, R., Hollingshead, J., Holman, E. A., & Moore, B. (1994). Preadolescents perceptions of AIDS before and after Earvin Magic Johnson's announcement. Journal of Pediatric Psychology, 19, 3-17.

1. Holman, E. A. (1990). Death and the health professional: Organization and defense in health care. Death Studies, 14, 13-24.
Grants
Robert Wood Johnson Foundation Nurse Faculty Scholar Grant: "Susceptibility to Acute Stress and Cardiovascular Ailments: A Gene-Environment Analysis" 2010-2013
National Science Foundation: A national longitudinal study of community trauma exposure. 1/1/2015-12/31/2017, Total costs: $333,396 SILVER (PI), HOLMAN (Co-PI)
National Science Foundation: RAPID: Responding to Terror of a Different Kind: A National Study of the Ebola Epidemic 12/1/14 - 11/30/15, Total costs: $ 160,306 SILVER (PI), HOLMAN (Co-PI)
National Institute of Nursing Research: Genetic variation, stress, and functional outcomes after stroke rehabilitation 7/1/2015-6/30/2020, Total costs: $2,718,925 HOLMAN (PI), CRAMER (PI)
Professional Societies
International Society for Traumatic Stress Studies
Association for Psychological Science
American Psychological Association, Divisions of Health Psychology and Trauma Psychology
California Association for Nurse Practitioners
Other Experience
Family Nurse Practitioner
Community Care Health Clinics 2002—2007

Last updated
11/06/2020