Elizabeth R. Jarvo

picture of Elizabeth R. Jarvo

Professor, Chemistry
School of Physical Sciences

Ph.D., Boston College, 2002
B.S., Acadia University, 1997

Phone: (949) 824-7105
Fax: (949) 824-8571
Email: erjarvo@uci.edu

University of California, Irvine
NS 1 4114
Mail Code: 2025
Irvine, CA 92697
Academic Distinctions
Japan Society for Promotion of Science (JSPS) Fellowship (2015)
ACS Women in Chemistry Committee Rising Star Award (2014)
Thieme Chemistry Journal Award (2010)
UCI School of Physical Sciences Outstanding Contributions to Undergraduate Education Award (2009)
NSF CAREER Award (2009)
PRF-Type G Award (2006)
Lilly New Faculty Award (2005)
Amgen New Faculty Award (2005)
NSERC Postgraduate Scholarship (1997, Declined)
Postdoctoral Fellow, Harvard University, 2002-2005
Research Abstract
Please see the Jarvo group website for a more detailed description and links to our publications: http://sites.uci.edu/jarvogroup/

Catalysts play a critical role in synthetic organic chemistry. The right catalyst can control a reaction's chemoselectivity and stereoselectivity, providing an efficient route to the required product. Many elegant syntheses of biologically active compounds rely on highly selective catalytic transformations for streamlined assembly of the required functional groups. The focus of our research interests is the development of new reactions using organometallic catalysts, and application of these transformations in complex target-oriented synthesis. In addition to providing valuable synthetic methods, these studies test and deepen our understanding of the fundamental principles that underlie reactivity.
(21) “Palladium-Catalyzed Cascade Reaction for Synthesis of Substituted Isoindolines” F. J. Williams, E. R. Jarvo Angew. Chem. Int. Ed. A. S. A. P.
(20) “Enantioselective Silver-Catalyzed Propargylation Reactions of Imines" H. M. Wisniewska, E. R. Jarvo Chemical Science, 2011, 2, 807-810.
(19) “Stereospecific Nickel-Catalyzed Cross-Coupling Reactions of Alkyl Ethers: Enantioselective Synthesis of Diarylethanes” B. L. Taylor, E. C. Swift, J. D. Waetzig, E. R. Jarvo J. Am. Chem. Soc. 2011, 133, 389.
(18) “Diene-Ligated Iridium Complexes as Catalysts for Allylation and Methallylation Reactions of Ketones” T. J. Barker, E. R. Jarvo Synthesis 2010, 19, 3259-3262.
(17) “Umpolung Amination: Nickel-Catalyzed Coupling Reactions of N,N-Dialkyl-N-chloroamines with Diorganozinc Reagents” T. J. Barker, E. R. Jarvo, J. Am. Chem. Soc. 2009, 131, 15598-15599
(16) “Diene-Ligated Iridium Catalyst for Allylation Reactions of Ketones and Imines” T. J. Barker, E. R. Jarvo, Org. Lett. 2009, 11, 1047-1049.
(15) “Palladium-Catalyzed, One-Pot, Three-Component Synthesis of Homoallylic Amines from Aldehyde Anisidine, and Allyl Trifluoroacetate” R. E. Grote, E. R. Jarvo, Org. Lett. 2008,11, 485-488.
(14) “Conjugate Allylation Reactions of Alkylidene Malonitriles Catalyzed by NHC-ligated Palladium Catalysts.” J.D. Waetzig, E.C. Swift, E.R. Jarvo, Tetrahedron, 2009, 65, 3197-3201.
(13) “Silver-Catalyzed, Manganese-Mediated Allylation Reactions of Aldehydes and Ketones.” N.T. Barczak, E.R. Jarvo, Eur. J. Org. Chem., 2008, 5507-5510.
(12) “Palladium-Catalyzed Conjugate Allylation of a,b-Unsaturated N-Acylpyrroles.” M.B. Shaghafi, B.L. Kohn, E.R. Jarvo, Org. Lett., 2008, 10, 4743-4746.
(11) “Catalytic Umpolung Allylation of Aldehydes by pi-Allylpalladium Complexes Containing Bidentate N-Heterocyclic Carbene Ligands.” N.T. Barczak, R.E. Grote, E.R. Jarvo, Organometallics, 2007, 26, 4863-4865
(10) “Efficient Total Syntheses of (-)-Colombiasin A and (-)-Elisapterosin B: Application of the Cr-Catalyzed Asymmetric Quinone Diels-Alder Reaction." A. A. Boezio, E.R. Jarvo, B.M. Lawrence, E.N. Jacobsen, Angew. Chem. Int. Ed. 2005, 44, 6046-6050.
(9) “Highly Enantio- and Regioselective Quinone Diels-Alder Reaction Catalyzed by a Tridentate [(Schiff Base)CrIII] Complex.” E.R. Jarvo, B.M. Lawrence, E.N. Jacobsen, Angew. Chem. Int. Ed. 2005, 44, 6043-6046.
(8) “Asymmetric Acylations.” E.R. Jarvo and S.J. Miller, Comprehensive Asymmetric Catalysis, Supplement 1; Jacobsen, E.N., Pfaltz, A., Yamamoto, H., Eds.; Springer-Verlag: Berlin, Heidelberg, 2004; Chapter 43.
(7) “Amino Acids and Peptides as Asymmetric Organocatalysts.” E.R. Jarvo and S.J. Miller, Tetrahedron, 2002, 58, 2481-2495.
(6) “Fluorescence-Based Screening of Asymmetric Acylation Catalysts Through Parallel Enantiomer Analysis. Identification of a Catalyst for Tertiary Alcohol Resolution.” E.R. Jarvo, C. A. Evans, G.T. Copeland, S.J. Miller. J. Org. Chem. 2001, 66, 5522-5527.
(5) “Incorporation of Peptide Isosteres into Enantioselective Peptide-Based Catalysts as Mechanistic Probes.” M.M. Vasbinder, E.R. Jarvo, S.J. Miller. Angew. Chem. Int. Ed. 2001, 40, 2824-2827.
(4) “Asymmetric Acylation Reactions Catalyzed by Conformationally Biased Octapeptides.” E.R. Jarvo, M.M. Vasbinder, S.J. Miller. Tetrahedron 2000, 56, 9773-9779.
(3) “A Biomimetic Approach to Asymmetric Acyl Transfer Catalysis.” E.R. Jarvo, G.T. Copeland, N. Papaioannou, P.J. Bonitatebus, Jr., and S.J. Miller J. Am. Chem. Soc. 1999, 121, 11638-11643.
(2) “Minimal Acylase-Like Peptides. Conformational Control of Absolute Stereospecificity.” G.T. Copeland, E.R. Jarvo and S. J. Miller. J. Org. Chem. 1998, 63, 6784-6785.
(1) “High-Pressure Diels-Alder Reactions of Quinone mono-ketals.” E.R. Jarvo, S.R. Boothroyd and M.A. Kerr. Synlett 1996, 879.
Professional Societies
American Chemical Society
Chao Family Comprehensive Cancer Center
Iota Sigma Pi
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