Arezoo Campbell
Associate Adjunct Professor, Community & Environmental Medicine
School of Medicine
School of Medicine
Ph.D., University of California, Irvine, 1999, Toxicology
University of California, Irvine
Department of Medicine
Center for Occupational and Env Health
Mail Code: 1830
Irvine, CA 92617
Department of Medicine
Center for Occupational and Env Health
Mail Code: 1830
Irvine, CA 92617
Research Interests
Neurotoxicology, Nanoparticles
Research Abstract
Research focus of my laboratory is on delineating the mechanisms by which environmental exposures may accelerate the pathogenesis of neurodegenerative disorders.
Publications
Campbell A., Araujo J.A., Li H., Sioutas C. Kleinman M. (2009) Particulate matter induced enhancement of inflammatory markers in the brains of Apolipoprotein E knockout mice. J Nanoscience & Nanotechnology 9:5099-5104.
Gerlofs-Nijland ME., Campbell A., Miller MR., Newby DE., Cassee FR. (2009) Toxicity of inhaled traffic related particulate matter. Journal of Physics: Conference Series 151: 012049
Campbell A., Wang K. (2009) Carbon-based nanoparticles and immune responses in the brain. J. Nanoneurosci. 1:116-119.
Gerlofs-Nijland M., Berlo D., Cassee F., Schins R., Wang K., Campbell A. (2010) Effect of subchronic exposure to diesel engine exhaust on proinflammatory markers in different regions of the rat brain. Particle & Fibre Toxicology. 7:12.
Cassee F.R., Campbell A., Boere A.J., McLean S.G., Duffin R., Krystek P., Gosens I., Miller M.R. (2012) The biological effects of subacute inhalation of diesel exhaust following addition of cerium oxide nanoparticles in atherosclerosis-prone mice. Environmental Research. 115:1-10.
Shaligram S., Campbell A. (2013) Toxicity of copper salts is dependent on solubility profile and cell type tested. Toxicology in Vitro. 27: 844-851.
Campbell A., Sharman E., Bondy S.C. (2013) Age-related differences in the response of the brain to chronic dietary melatonin. AGE. DOI: 10.1007/s11357-013-9542-y
Lung, S. Li, H. Bondy S.C., Campbell A. (2013) Low concentrations of copper in drinking water increases AP-1 binding in the brain. Toxicology and Industrial Health. [Epub ahead of print].
Guerra R., Vera-Aguilar E., Uribe-Ramirez M., Gookin G., Camacho J., Osornio-Vargas A. R., Mugica-Alvarez V., Angulo-Olais R., Campbell A., Froines J., Kleinman T.M., De Vizcaya-Ruiz A. (2013) Exposure to inhaled particulate matter activates early markers of oxidative stress, inflammation and unfolded protein response in rat striatum. Toxicology Lett. 222:146-154.
Gerlofs-Nijland ME., Campbell A., Miller MR., Newby DE., Cassee FR. (2009) Toxicity of inhaled traffic related particulate matter. Journal of Physics: Conference Series 151: 012049
Campbell A., Wang K. (2009) Carbon-based nanoparticles and immune responses in the brain. J. Nanoneurosci. 1:116-119.
Gerlofs-Nijland M., Berlo D., Cassee F., Schins R., Wang K., Campbell A. (2010) Effect of subchronic exposure to diesel engine exhaust on proinflammatory markers in different regions of the rat brain. Particle & Fibre Toxicology. 7:12.
Cassee F.R., Campbell A., Boere A.J., McLean S.G., Duffin R., Krystek P., Gosens I., Miller M.R. (2012) The biological effects of subacute inhalation of diesel exhaust following addition of cerium oxide nanoparticles in atherosclerosis-prone mice. Environmental Research. 115:1-10.
Shaligram S., Campbell A. (2013) Toxicity of copper salts is dependent on solubility profile and cell type tested. Toxicology in Vitro. 27: 844-851.
Campbell A., Sharman E., Bondy S.C. (2013) Age-related differences in the response of the brain to chronic dietary melatonin. AGE. DOI: 10.1007/s11357-013-9542-y
Lung, S. Li, H. Bondy S.C., Campbell A. (2013) Low concentrations of copper in drinking water increases AP-1 binding in the brain. Toxicology and Industrial Health. [Epub ahead of print].
Guerra R., Vera-Aguilar E., Uribe-Ramirez M., Gookin G., Camacho J., Osornio-Vargas A. R., Mugica-Alvarez V., Angulo-Olais R., Campbell A., Froines J., Kleinman T.M., De Vizcaya-Ruiz A. (2013) Exposure to inhaled particulate matter activates early markers of oxidative stress, inflammation and unfolded protein response in rat striatum. Toxicology Lett. 222:146-154.
Campbell A., Daher N., Solaimani P., Mendoza K., Sioutas C. (2014) Human Brain Derived Cells Respond in a Type-Specific Manner after Exposure to Urban Particulate Matter (PM). Toxicol. In Vitro. 28:1290-1295.
Campbell A. (2014) Does Exposure to Air Pollution Contribute to Neurodegenerative Disease. Proceedings of the U.S.-Iran Symposium on Air Pollution in Megacities. Pg. 145-149: http://www.aaas.org/report/Iran-airpollution
lung S., Cassee F.R., Gosens I., Campbell A. (2014) Brain Suppression of AP-1 by Inhaled Diesel Exhaust and Reversal by Cerium Oxide Nanoparticles. Inhalation Toxicol. 26:636-641.
Campbell A. & Solaimani P. 2016. Inflammation, Oxidative Stress & Age-Related Disease In: Inflammation, Aging, and Oxidative Stress (eds. Bondy S.C. & Campbell A.) Springer Nature, Humana Press, pp. 95-106.
Heusinkveld H.J., Wahle T., Campbell A., Westerink R.H.S., Tran L., Johnston H., Stone V., Cassee F.R., Schins R.P.F. (2016) Neurodegenerative and neurological disorders by small inhaled particles. NeuroToxicology. 56:94-106.
Solaimani P., Saffari A., Sioutas C., Campbell A. (2016) Exposure to airborne ambient ultrafine particulate matter alters the expression of several noncoding RNAs and metallothioneins in primary human neurons. NeuroToxicology. 58:50-57.
Bondy S.C. & Campbell A. 2017. Aluminum and Neurodegenerative Diseases In: Advances in Neurotoxicology, Vol. 1 (eds. Aschner M. & Costa L.G.) Academic Press, pp. 131-156.
Bondy S.C. & Campbell A. (2017) Water quality and brain function. Int. J. Environ. Res. Public Health. 15(1) pii: E2. doi: 10.3390/ijerph15010002.
Bliss B., Tran K.I., Sioutas C., Campbell A. (2018) Ambient ultrafine particles activate human monocytes: Effect of dose, differentiation state and age of donors. Environ. Res. 161:314-320.
Professional Societies
American Association for the Advancement of Science
Society for Neuroscience
Society of Toxicology
Link to this profile
https://faculty.uci.edu/profile/?facultyId=4969
https://faculty.uci.edu/profile/?facultyId=4969
Last updated
03/20/2018
03/20/2018