Richard H Lathrop


Associate Professor
Donald Bren School of Information and Computer Sciences
Vice-Chair of Undergraduate Education
Other not listed

B.A., Reed College, Mathematics
PhD, Artificial Intelligence, MIT

Phone: (949) 824-4021
Fax: (949) 824-4056
Email: rickl@uci.edu

University of California, Irvine
464E CS
Dept. of Info. and Computer Science
Mail Code: 3425
Irvine, CA 92697
Research Interests
Bioinformatics, computational biology,
machine learning, artificial intelligence,
protein structure prediction, drug discovery,
genetic regulation.
URL
Academic Distinctions
AAAI/IAAI Innovative Application, DAC Best Paper, MIT Sprowl, US Patent No. 5,526,281, NSF CAREER and Fellowship, UCI Excellence in Teaching, ICS Outstanding Faculty Teaching and Research, Covers of CACM, JMB, AI Magazine
Research Abstract
Dr. Lathrop's research for the last 15 years has involved applying intelligent systems and advanced computation to problems in molecular biology. He has broad interests in computational molecular biology, including current research interests in protein structure prediction from sequence, protein-DNA interactions and genetic regulation, rational drug design and discovery, and other molecular structure/function relationships.
Available Technologies
Publications
"Combinatorial Optimization in Rapidly Mutating Drug-Resistant Viruses," Lathrop, R.H., Pazzani, M.J., J. Combinatorial Optimization, 3:301-320, 1999.
 
"An Anytime Local-To-Global Optimization Algorithm for Protein Threading in O(m2n2) Space," Lathrop, R.H. J. Computational Biology, 6(3/4):405-418, 1999.
 
"A Bayes-Optimal Probability Theory that Unifies Protein Sequence-Structure Recognition and Alignment." Lathrop, R.H., Rogers, R.G. Jr., Smith, T.F., White, J.V., Bull. Math. Biol., 60:1039-1071, 1998.
 
"Current Limitations to Protein Threading Approaches," Smith, T.F., Lo Conte, L., Bienkowska, J., Gaitatzes, C., Rogers, R.G. Jr., and Lathrop, R.H., J. Computational Biol., 4(3):217-225, 1997.



 
"Solving the Multiple-Instance Problem with Axis-Parallel Rectangles," Dietterich, T.G., Lathrop, R.H., Lozano-Perez, T., Artificial Intelligence, 89:31-71, 1997.
20(1):13--25, Spring, 1999.
Professional Societies
American Association for Artificial Intelligence (Life Member)
International Society for Computational Biology (member of the founding Board of Directors)
Last updated
02/26/2002