Shin Lin

picture of Shin  Lin

Professor, Developmental & Cell Biology
School of Biological Sciences

Professor of Biomedical Engineering
The Henry Samueli School of Engineering

Professor of Physiology and Biophysics
School of Medicine

Ph.D., UCLA, 1971, Biological Chemistry
M.S., San Diego State University, 1967, Chemistry
B.S., U.C. Davis, 1965, Chemistry

Phone: (949) 824-4696
Fax: (949) 824-4709

University of California, Irvine
4230 McGaugh Hall
Mail Code: 2300
Irvine, CA 92697
Research Interests
Complementary and alternative medicine, mind/body signaling, qigong, tai chi, acupuncture, exercise physiology
Academic Distinctions
NIH Research Career Development Awardee (1976-1981).
Fellow, American Association for Advancement of Science (elected 1982).
President, Society of Chinese Biophysicists in America (1996).
Co-Chair, 7th World Congress for Qigong (2004, 2005).
Postdoctoral Fellow, Department of Biochemistry & Biophysics, University of California, San Francisco (1971-1974).
Research Abstract
Dr. Lin's laboratory is using hi-tech approaches (e.g., Heart Rate Variability analysis of Electrocardiogram, Independent Component Analysis of Electroencephalogram, Electromyography, Laser Doppler Flowmetry measurement of blood flow, Infra Red Thermography for monitoring body temperature,Single Square Voltage Pulse method for measurement of conductance and capacitance at acupuncture points, Gas Discharge Visualization of bioelectrical fields, Single Photon Counting of biophoton emission, etc. ) to study physiological changes in mind/body functions and bioenergy fields associated with mind-body practices and acupuncture therapy, two major modalities of complementary and alternative medicine.
Lin, S., Z.Y. Shen, T. Ross, G. Chevalier, and K.M.Shu. (2005). Analysis of factors influencing the use of heart rate variability for evaluation of autonomic nervous function in mind-body and acupuncture research. J. Alternative. & Complementary Med., in press.
Lin, S., G. Chevalier, T. Ross, M. Nguyen, and H. Lin. (2005). Variability and specificity of the single square voltage pulse method for measuring conductance at acupuncture points for mind-body research. J. Alternative & Complementary Med., in press.
Lin, S., G. Chevalier, H. Lin, T. Ross, and P. Lin. (2005). Measurement of biophoton emission with a single photon counting system. J. Alternative & Complementary Med., in press.
Lin, S., G. Chevalier, T. Ross, M. Nguyen, H. Lin, P. Lin, and Y. Lin. (2004). Comparison of bioenergy and physiological markers in qigong and acupuncture research. J. Alternative & Complementary Med., Vol. 15, p. 1135.
Lin, S. Changes in mind/body functions associated with qigong practice. (2004) J. Alt. & Compl. Med., Vol. 10, p. 200.
Hintz, K.J., G.L. Yount, I. Kadar, G. Schwartz, R. Hammerschlag, and S. Lin. (2003). Bioenergy definitions and research guidelines. Alternative Therapies for Health and Medicine 9: A13-30.
Zamir, E, M. Katz, Y. Posen, N. Erez, K. M. Yamada, B. Z. Katz, S. Lin, D. C. Lin, A. Bershadsky, Z. Kam, B. Geiger. (2000). Dynamics and segregation of cell-matrix adhesions in cultured fibroblasts. Nature Cell Biol. 2: 191-1966.
Pankov, R, E. Cukierman, B. Z. Katz, K. Matsumoto, D. C. Lin, S. Lin, C. Hahn, K. M. Yamada, (2000). Integrin dynamics and matrix assembly: tensin-dependent translocation of alpha (5) -beta (1) integrins promotes early fibronectin fibrillogenesis. J. Cell Biol. 148: 1075-1090.
Lin, C. C., J. F. Apgar, W. J. Mahlow, and S. Lin. (1997). Flourescence localization of tensin at cell-substrate contacts in living fibroblasts. Cell Vision 4: 181-182.
Chuang, J. Z., D. C. Lin, and S. Lin. (1995). Molecular cloning, expression, and mapping of the high affinity actin-capping domain of chicken cardiac tensin. J. Cell Biol. 128: 1095-1109.
Davis, S., M.L. Lu, S.H. Lo, S. Lin, J.A. Butler, B.J. Druker, T.M. Roberts, Q. An, and L.B. Chen. (1991). Presence of an SH2 domain in the actin-binding protein tensin. Science 252: 712-715.
Saltzman, W. M., P. Parsons-Wingarter, K. W. Leong, and S. Lin. (1991). Fibroblast and hepatocyte behavior on synthetic polymer surfaces. J. Biomed. Materials Res. 25, 741-759.
Casella, J.F., M.D. Flanagan,and S. Lin.(1981). Cytochalasin D inhibits actin polymerization and induces depolymerization of actin filaments formed during platelet shape change. Nature 293:302-305.
Spudich, J.A., and S. Lin. (1972). Cytochalasin B, its interaction with actin and actomyosin from muscle. Proc. Natl. Acad. Sci., U.S.A. 69: 442?446.
Professional Societies
American Society for Cell Biology
American Society of Biochemistry and Molecular Biology
Biophysical Society
American Association for the Advancement of Science
Other Experience
Editorial Board
Journal of Alternative and Complementary Medicine 2003

Editorial Board
Chinese Medicine Journal 2005

Founding Director
International Alliance for Mind/Body Signaling & Energy Research 2002

Scientific Board
UCI's Susan Samueli Center for Integrative Medicine 2003

Graduate Programs
Cell Biology

Structural Biology and Molecular Biophysics

Interdepartmental Neuroscience Program

Cellular and Molecular Biosciences

Research Centers
Susan Samueli Center for Integrative Medicine
Center for Biomedical Engineering
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