Nephrotic syndrome, Diabetes, Hypertension
Dr. Barton’s research involves the effect of renal disease and nephrotoxic insults on magnesium metabolism. He is also active in studies of the pathophysiology of nephrotic syndrome, diabetic nephropathy and hypertension.
Vaziri, N.D., Gonzales, E.C., Shayestehfar, B., Barton, C.H.: Plasma levels and urinary excretion of fibrinolytic and protease inhibitory proteins in nephrotic syndrome. J. Lab. Clin. Med. 124(1): 118-124, 1994.
Hon, G., Vaziri, N.D., Kaupke, C.J., Tehranzadeh, A., Barton, C.H.: Lack of a fast-acting effect of erythropoietin on arterial blood pressure and endothelin level. Artif. Organs 19(2):188-191, 1995.
Vaziri, N.D., Liang, K., Barton, C.H.: Effect of increased afterload on cardiac lipoprotein lipase and VLDL receptor expression. Biochem. Biophys ACTA 1436:577-584, 1999.
Barton, C.H., Ni, Z., Vaziri, N.D.: Effect of severe aortic banding above the renal arteries on nitric oxide synthase isotype expression. Kidney International 59:654-661, 2001.
Barton, C.H., Ni, Z., Vaziri, N.D.: Enhanced nitric oxide inactivation in aortic coarctation-induced hypertension. Kidney International 60:1083-1087, 2001.
Barton, C.H., Ni, Z., Vaziri, N.D.: Blood pressure response to hypoxia: Role of nitric oxide synthase. Am J of Hypertension, 16:1043-1048, 2003.
Ni, Z., Hou, S., Barton, C.H., Vaziri, N.D.: Lead exposure raises superoxide and hydrogen peroxide in human endothelial and vascular smooth muscle cells. Kidney Int 66:2329-2336, 2004.
Vaziri, N.D., Ding, Y., Ni, Z., Barton, C.H.: Bradykinin downregulates whereas arginine analogues upregulate eNOS expression in coronary endothelial cells. J Pharmacol Exp Ther 313: 121-126, 2005.
Aminzadeh, A., Pahl, M.V., Barton, C.H., Dotor, NS, Vaziri, N.D.: Human uremic plasma stimulates release of leptin and uptake of tumor necrosis factor-? in visceral adipocytes. Nephrol Dial Transplant. 2009 Dec;24(12):3626-31. Epub 2009 Aug 7
Member, Alpha Omega Alpha Honor Medical Society, Zeta Chapter
Director, Board of Directors, Southern California Renal Disease Council, Inc., ESRD Network 18