Professor Emeritus, Dermatology
School of Medicine

Dean Emeritus, Dermatology
School of Medicine

Psoriasis, skin cancer, dermatopharmacology, clinical research in dermatology, Phototherapy, methotrexate, cyclosporin, immunomodulators/dermatology, photoaging skin, dermatology therapies.

www.ucihs.uci.edu/derm/Derm%20Faculty.htm

National Psoriasis Fndn, Life-Time Achievement award; American Skin Assoc, Psoriasis Research Award

Basic and clinical research investigations into the understanding of hyperproliferative skin diseases, such as psoriasis, ichthyosis, and skin cancer. Studies include the kinetics of cellular proliferation in these diseases, biochemical aspects of the DNA synthesis pathways and the mechanism of action of chemotherapeutic drugs to provide beneficial or therapeutic effects in these diseases. These investigations involve clinical pharmacology of experimental and older drugs as they are used therapeutically, e.g. the use of methotrexate for psoriasis. Further directions of dermatopharmacologic research include the topical use of chemotherapy for psoriasis and the use of photodynamic agents for psoriasis and other skin diseases.

Topical and systemic drug development for skin diseases in collaboration with pharmaceutical companies. Protocol design for dermatologic disease therapies, investigator INDs prepared, Phase I-III participation, consultation, or administration. Participation in past with over 20 major pharmaceutical companies in basic and clinical dermatopharmacology research.

Weinstein, G.D., Nigra, T.P., Pochi, P.E., Savin, R.C., Allan, A., Benik, K., Jeffes, E., Lufrano, L., and Thorne, E.G.: Topical Tretinoin for Treatment of Photodamaged Skin: A Multicenter Study. 127: 659-665, May 1991.

Weinstein, G.D., and White, G.: Rotational Approach to therapy for Moderate to Severe Psoriasis. 28(3): 454-459, March 1993.

Liem, W., McCullough, J.L., and Weinstein, G.D.: Effectiveness of Topical Therapy for Psoriasis: Results of a a National Survey. 55:306-310, 1995.

Greaves, M., and Weinstein, G.: Drug Therapy, Treatment of Psoriasis. 332: 581-589, 1995.

Jeffes, E.W.B., McCullough, J.L., McCormick, A., Almanzor, J., Liu, G., Dang, M., Voss, K., Voss, J., Schlotzhauer, A., and Weinstein, G.D.: Methotrexate Therapy of Psoriasis: Differential Sensitivity of Proliferating Lymphoid and Epithelial Cells to the Cytotoxic and Growth-Inhibitory Effects of Methotrexate. 104: 183-188, 1995.

Amer Acad Derm, Soc of Invest Derm, ADA

Link to this profile
https://faculty.uci.edu/profile/?facultyId=2382

Last updated
03/30/2006