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 Thomas E. Lane

University of California

McGaugh Hall Rm 2238
 Mail Code: 3900
 Irvine, CA 92697

PHONE: (949) 824-5878
FAX: (949) 824-8551

E-MAIL: tlane@uci.edu

 

Thomas E. Lane
Professor, Molecular Biology and Biochemistry
School of Biological Sciences
 Director, Biotechnology Master's Program, Molecular Biology and Biochemistry
School of Biological Sciences
B.S., Ball State University, 1988
Ph.D. 1993, University of California, Los Angeles
Research Interests
multiple sclerosis, demyelination, chemokines, inflammation, virology, immunology

Faculty/lab web:
http://darwin.bio.uci.edu/~faculty/lane
 
Graduate Programs:
 Virology Immunology and Pathogenesis Neurobiology
 
Professional Society American Society of Virology The American Association of Immunologists American Society for Microbiology International Society for Neuroimmunology
 
Abstract
see web site


Other Experience
Updated: Last Updated: 06/29/2009

  Cliffe, L.J., N.E. Humphreys, T.E. Lane, C.S. Potten, C. Booth, and R.K. Grencis (2005). Accelerated intestinal epithelial cell turnover: a new mechanism of parasite expulsion. Science. 308(5727):1463.

Held, K.S., B.P. Chen, W.A. Kuziel, B.J. Rollins, and T.E. Lane (2004). Differential roles of CCL2 and CCR2 in host defense to coronavirus infection. Virology. 329(2):251.

Trifilo, M.J. and T.E. Lane (2004). The CC chemokine ligand 3 (CCL3) regulates CD11c+CD11b+CD8_- dendritic cell maturation and activation following viral infection of the central nervous system: Implications for a role in T cell activation. Virology. 327(1):8-15.

Totoiu, M.O., G.I. Nistor, T.E. Lane, and H.S. Keirstead (2004). Remyelination, axonal sparing, and locomotor recovery following transplantation of glial-committed progenitor cells into the MHV model of multiple sclerosis. Exp. Neurol. 187(2):254-265.

Glass, W.G., M.J. Hickey, J.L. Hardison, M.T. Liu, J.E. Manning, and T.E. Lane (2004). Antibody targeting of the CC chemokine ligand 5 (CCL5) results in diminished leukocyte infiltration into the central nervous system and reduced neurologic disease in a viral model of multiple sclerosis. J. Immunol. 172(7):4018-4025.

Trifilo, M.J., C. Montalto-Morrison, L.N. Stiles, K.R. Hurst, J.L. Hardison, J.E. Manning, P.S. Masters, and T.E. Lane (2004). The chemokine CXCL10 controls viral infection in the central nervous system: Evidence for a role in innate immune response through recruitment and activation of Natural Killer cells. J. Virol., 78(2):585-594.
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