| Claudia H. Kawas | |
Positions: |
Professor, Neurology School of Medicine Professor, Neurobiology and Behavior School of Biological Sciences 
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Degree: |
M.D., University of Louisville, Kentucky |
Research |
Dementia and Memory Disorders, Geriatric Neurology, Epidemiology |
Abstract: |
Claudia Kawas, M.D., Al and Trish Nichols Chair in Clinical Neuroscience and Professor of Neurology and Neurobiology & Behavior, at the University of California, Irvine, is a clinician and researcher in the areas of aging and dementia. Her work is concentrated on the epidemiology of aging and Alzheimer's disease, developing research in the determinants of successful aging, longitudinal and clinical pathological investigations, and most recently, studies in cognitive and functional abilities of the Oldest Old (over 90 years of age). Dr. Kawas is a graduate of Swarthmore College (Pennsylvania), who completed her medical studies at the University of Louisville (Kentucky) in 1978. After completing her neurology residency and fellowship in dementia and aging at Albert Einstein College of Medicine, Bronx, New York, she joined the faculty at Johns Hopkins School of Medicine, where she remained for 15 years, and collaborated with the National Institute on Aging in their investigations involving the Baltimore Longitudinal Study of Aging. In 2000, Dr. Kawas moved to the University of California, Irvine, where she is Associate Director of the Institute for Brain Aging and Dementia. Dr. Kawas is currently a member of the Scientific Advisory Board of several organizations. |
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Corrada M, Brookmeyer R, Berlau D, Paganini-Hill A, Kawas C. Prevalence of dementia after age 90: Results from The 90+ Study. Neurology. 71(5):337-343,2008. |
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Head E, Corrada M, Kahle-Wrobleski K, Kim R, Sarsoza F, Goodus M, Kawas C. Synaptic proteins, neuropathology and cognitive status in the oldest-old. Neurobiology of Aging, Epub Nov 12, 2007. |
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Kawas, C, The Oldest Old and the 90+ Study. Alzheimer’s & Dementia, January 2008, Vol. 4, Issue 1, Suppl 1, S56-S59 |
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Grober E, Hall CB, Lipton RB, Zonderman AB, Resnick SM, Kawas C. Memory Impairment, Executive Dysfunction, and Intellectual Decline in Preclinical Alzheimer’s Disease. JINS, 2008, 14, 266-278. |
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Berlau DJ, Kahle-Wrobleski K, Head E, Goodus M, Kim R, Kawas C. Dissociation of Neuropathologic Findings and Cognition. Case Report of an Apolipoprotein E ?2/?2 Genotype. Arch Neurol, Aug 2007, Vol. 64 (No. 8), 1193-1196. |
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Nistor M, Don M, Parekh M, Sarsoza F, Goodus M, Lopez GE, Kawas C, Leverenz J, Doran E, Lott IT, Hill M, Head E. Alpha- and Beta-Secretase Activity as a Function of Age and Beta-Amyloid in Down Syndrome and Normal Brain. Neurobiology of Aging, 2007, 28; 1493-1506. |
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Ringman JM, Rodriguez Y, Diaz-Olavarrieta C, Chavez M, Thompson M, Fairbanks L, Paz F, Varpetian A, Chaparro H, Macias-Islas MA, Murrell J, Ghetti B, Kawas C. Performance on MMSE Sub-Items and Education Level in Presenilin-1 Mutation Carriers Without Dementia. International Psychogeriatrics, 2007, 19:2, 323-332. |
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Paganini-Hill A, Kawas CH, Corrada MM. Non-alcoholic beverage and caffeine consumption and mortality: the Leisure World Cohort Study. Preventive Medicine, 44, 2007, 305-310. |
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Whittle C, Corrada MM, Dick M, Ziegler R, Kahle-Wrobleski K, Paganini-Hill A, Kawas C. Neuropsychological Data in Non-Demented Oldest-Old: The 90+ Study. Journal of Clinical & Experimental Neuropsychology, 2007,29 (3), 290-299. |
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Paganini-Hill A, Kawas CH, Corrada MM. Type of Alcohol Consumed, Changes in Intake Over Time and Mortality: The Leisure World Cohort Study. Age and Ageing, 2007, 36:203-209. |
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Kahle-Wrobleski K, Corrada MM, Li B, Kawas CH. Sensitivity and Specificity of the Mini-Mental State Examination for Identifying Dementia in the Oldest-Old: The 90+ Study. JAGS, 2007, 55:284-289. |
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Murrell J, Ghetti B, Cochran E, Macias-Islas MA, Medina L, Varpetian A, Cummings JL, Mendez MF, Kawas C, Chui H, Ringman JM. The A431E Mutation in PSEN1 Causing Familial Alzheimer’s Disease Originating in Jalisco State, Mexico: An Additional Fourteen Families. Neurogenetics. 2006, 7:277-279. |
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Kawas CH, Corrada MM. Alzheimer’s and Dementia in the Oldest-Old: A Century of Challenges. Current Alzheimer Research, 2006, 3, 411-419. |
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Kawas CH, Medications and Diet: Protective Factors for AD? Alzheimer Dis Assoc Disord, 2006 July/Sept; 20 Suppl 2:S89-S96. |
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Kawas C. Diet and the Risk of Alzheimer’s Disease. Editorial. Annals of Neurology, June 2006, Vol. 59, No. 6, 877-879. |
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Corrada MM, Kawas CH, Mozaffar F, Paganini-Hill A. Association of body mass index and weight change with all-cause mortality in the elderly. Am J Epidemiol, 2006, 163:938-949. |
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Paganini-Hill A, Corrada M, Kawas C. Increased Longevity in Older Users of Postmenopausal Estrogen Therapy: The Leisure World Cohort Study, Menopause, 2006, Vol 13, No. 1,12-18. |
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Lopez OL, Becker JT, Jagust WJ, Fitzpatrick A, Carlson MC, DeKosky ST, Breitner J, Lyketsos CG, Jones B, Kawas C, Kuller LH, Neuropsychological characteristics of mild cognitive impairment subgroups. J Neurol Neurosurg Psychiatry, 2005, Aug 15, 159-165. |
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Ringman JM, Diaz-Olavarrieta C, Rodriguez Y, Chavez M, Fairbanks L, Paz F, Varpetian A, Maldonado HC, Macias-Islas MA, Murrell J, Ghetti B, Kawas C, Neuropsychological Function in Non-Demented Carriers of Presenilin-1 Mutations, Neurology, 2005, Aug 23; 65(4):552-8. |
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Corrada M, Kawas C, Hallfrisch J, Muller D, Brookmeyer R. Reduced Risk of Adlzheimer's Disease with High Folate Intake: The Baltimore Longitudinal Study of Aging, Alzheimer's and Dementia, 2005, 1, 11-18. |
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Dal Forno G, Palermo MT, Donohu JE, Karagiozis H, Zonderman AB, Kawas CH. Depressive Symptoms, Sex, and Risk for Alzheimer’s Disease. Annals of Neurology, 2005, Mar, Vol 57, No 3, 381-387. |
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Lopez OL, Kuller LH, Becker JT, Jagust WJ, DeKosky ST, Fitzpatrick A, Breitner J, Lyketsos C, Kawas C, Carlson M, Classification of vascular dementia in the Cardiovascular Health Study Cognition Study, Neurology, 2005, May 10;64(9):1539-47. |
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Mikolaenko I, Pletnikova O, Kawas CH, O’Brien R, Resnick SM, Crain B, Troncoso JC, Alpha-Synuclein Lesions in Normal Aging, Parkinson Disease, and Alzheimer Disease: Evidence from the Baltimore Longitudinal Study of Aging (BLSA), J Neuropathol Exp Neurolol, 2005, Vol 65, 2, 156-162. |
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Fitzpatrick AL, Kuller LH, Lopez OL, Kawas CH, Jagust W, Survival following dementia onset: Alzheimer’s disease and vascular dementia, J Neurol Sci, 2005, Mar 15; 229-230:43-9. |
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Kuller LH, Lopez OL, Jagust WJ, Becker JT, DeKosky ST, Lyketsos C, Kawas C, Breitner JCS, Fitzpatrick A, Dulberg C, Determinants of vascular dementia in the Cardiovascular Health Cognition Study, Neurology, 2005, May, 64, 1548-1552. |
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Yasar S, Corrada M, Brookmeyer R, Kawas, C, Calcium Channel Blockers and Risk of AD: The Baltimore Longitudinal Study of Aging, Neurobiology of Aging, 2005, 26, 157-163. |
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West MJ, Kawas CH, Stewart WF, Rudow GL, Troncoso JC, Hippocampal neurons in pre-clinical Alzheimer's disease. Neurobiology of Aging, 2004, 25, 1205-1212. |
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Gottschalk LA, Kawas C, Hoang A, Bechtel RJ, Computerized Neuropsychiatric Assessment of Geriatric Subjects by Content Analysis of Brief Samples of Their Speech, CIN: Computers, Informatics, Nursing, 2004, Nov/Dec, Vol 22, No 6, 351-355. |
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Mulnard RA, Corrada MM, Kawas CH, Estrogen Replacement Therapy, Alzheimer’s Disease, and Mild Cognitive Impairment, Current Neurology and Neuroscience Reports 2004, 4:368-373. |
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Fonesca MI, Kawas CH, Troncoso JC, Tenner AJ, Neuronal Localization of C1q in Preclinical Alzheimer's Disease, Neurobiology of Disease 15 (2004) 40-46. |
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Moffat SD, Zonderman AB, Metter EJ, Kawas C, Blackman MR, Harman SM, Resnick SM, Free Testosterone and Risk for Alzheimer Disease in Older Men, Neurology, 2004, Jan, 62:188-193. |
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Lopez OL, Jagust WJ, Dulberg C, Becker JT, DeKosky ST, Fitzpatrick A,, Breitner J, Lyketsos C, Jones B, Kawas C, Carlson M, Kuller LH, Risk Factors for Mild Cognitive Impairment in the Cardiovascular Health Study Cognitive Study, Part 2, Arch Neurol, 2003; 60:1394-1399. |
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Lopez OL, Jagust WJ, DeKosky ST, Becker JT, Fitzpatrick A, Dulberg C, Breitner J, Lyketsos C, Jones B, Kawas C, Carlson M, Kuller LH, Prevalence and Classification of Mild Cognitive Impairment in the Cardiovascular Health Study Cognitive Study, Part 1. Arch Neurol, 2003; 60:1385-1389. |
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Kawas CH, Early Alzheimer's Disease, New England Journal of Medicine, 2003;349:1056-63. |
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Kawas CH, Corrada MM, Brookmeyer R, Morrison A, Resnick SM, Zonderman AB, Arenberg D. Visual Memory Predicts Alzheimer's Disease More Than a Decade Before Diagnosis. Neurology, 2003 Apr, 60(7):1089-1093. |
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Brookmeyer R, Corrada M, Curriero FC, Kawas C, Survival Following a Diagnosis of Alzheimer's Disease. Archives of Neurology, 2002 Nov, 59(11):1764:7. |
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Kawas CH, Brookmeyer R, Aging and the public health effects of dementia. Editorial. New England Journal of Medicine, 2001 Apr 12; 344(15):1160-1. |
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Mulnard R, Cotman C, Kawas C, van Dyck C, Sano M, Doody R, Koss E, Pfeiffer E, Jin S, Gamst A, Grundman M, Thomas R, Thal, L, for the Alzheimer's Disease Cooperative Study: Estrogen Replacement Therapy for Treatment of Mild to Moderate Alzheimer Disease: A Randomized Controlled Trial. Journal of the American Medical Association. 283:1007-1015, Feb 23, 2000; Neurology Vol. 54:2072-2077, 2000. |
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Kawas C, Gray S, Brookmeyer R, Fozard J. Zonderman A: Age-specific incidence rates of Alzheimer's Disease. The Baltimore Longitudinal Study of Aging. Neurology, 54(11): 2072-7, Jan 2000. |
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La Ferla F, Troncoso J, Strickland D, Kawas C, Jay G: Neuronal Cell Death in Alzheimer’s Disease Correlates with apoE Uptake and Intracellular Ab Stabilization. Journal of Clinical Investigations, Vol 100, Number 2, 310-320, July 1997. |
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Kawas C, Resnick S, Morrison A, Brookmeyer R, Corrada M, Zonderman A, Baccall C, Lingle D, Metter J: A Prospective Study of Estrogen Replacement Therapy and the Risk of Developing Alzheimer's Disease: The Baltimore Longitudinal Study of Aging. Neurology Vol. 48, No. 6, 1517-1521, 1997. |
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Stewart W, Kawas C, Corrada M, Metter J: Risk of Alzheimer's Disease and Duration of NSAIDs Use. Neurology. Vol 48, No 3, 626-632, 1997. |
Professional
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American Neurological Association |
| Society of Neurosciences | |
| American Academy of Neurology | |
| American Geriatric Society | |
| American Medical Association | |
| National Arab American Medical Association | |
Address |
University of California 1121 Gillespie Mail Code: 4540 Irvine, CA 92697 |
Phone: | (949) 824-2323 |
Fax: | (949) 824-4165 |
Email: | ckawas@uci.edu |
| Institute for Brain Aging and Dementia |
| Updated | 10/15/2008 |
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