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Karen L. Edwards

PhD, Epidemiology
School of Medicine

Ph.D., University of Washington, 1996, Epidemiology


M.S., California State University, Chico, 1991, Nutrition

Phone: (949) 824-9054
Email: kedward1@uci.edu

University of California, Irvine
224 Irvine Hall
Mail Code: 7550
Irvine, CA 92697


Research
Interests
Genetic Epidemiology, epidemiology, chronic diseases, diet and nutritional epidemiology, Gene x Environment interactions
   
Research
Abstract
My primary research focus is in genetic epidemiology and the use of multivariate approaches to define phenotypes for complex diseases. My genetic epidemiology research covers a broad range of conditions, including diabetes, metabolic syndrome, cardiovascular disease, melanoma and Parkinsons Disease. I am also interested in interactions between envrionmental factors (particularly diet) and genetic susceptibility (Gene x environment interactions). Finally, I work on several interdisciplinary projects that focus on the ethical, legal or social implications of genomics and applicatiosn to clinical and public health practice.

Teaching: Epidemiology202 : Genetic Epidemiology. Offered spring quarter
   
Publications Selected Publications (from over 90)
Edwards KL, Hutter CM, Yin Wan J, Kim H, Monks SA. Genome-wide Linkage Scan for the Metabolic Syndrome: The GENNID Study. Obesity. 2008;16(7):1596-1601. PMID: 18421265

Edwards KL, Wan JY, Hutter CM, Fong PY, Santorico S. Multivariate Linkage Scan for Metabolic Syndrome in families with type 2 diabetes. Obesity. 2011; 19(6):1235-43. PMID: 21183932

Ziogas A, Horick NK, Kinney AY, Lowery JT, Domchek SM, Isaacs C, Griffin CA, Moorman PG, Edwards KL, Hill DA, Berg JS, Tomlinson GE, Anton-Culver H, Strong LC, Kasten CH, Finkelstein DM, Plon SE. Clinically Relevant Changes in Family History of Cancer over Time. JAMA. 2011; 306(2):172-178. PMID: 21750294

Bowen D, Jabson J, Haddock N, Edwards K. Skin Care Behaviors among Melanoma Survivors. Psychooncology. 2011 Jul 21.doi:10.1002/pon.2017. PMID: 21780240.

Edwards KL, Lemke AA, Trinidad SB, Lewis SM, Starks H, Snapinn KW, Griffin MQ, Wiesner GL, Burke W. Genetics Researchers’ and IRB Professionals’ Attitudes toward Genetic Research Review: A Comparative Analysis. Genet Med. 2012 Feb; 14(2):236-42. doi: 10.1038/gim.2011.57. PMID: 22241102

Edwards KL, Lemke AA, Trinidad SB, Lewis SM, Starks H, Griffin MT, Wiesner GL. The GRRIP Consortium. Attitudes toward genetic research review: Results from a survey of human genetics researchers. Public Health Genomics. 2011; 14(6):337-45. PMID: 21487211.

Tsuang D, Leverenz JB, Lopez OL, Hamilton RL, Bennett DA, Schneider JA, Buchman AS, Larson EB, Crane PK, Kaye JA, Kramer P, Schellenberg GD, Watson GS, Kukull W, Nelson PT, Jicha GA, Neltner JH, Galasko D, Masliah E, Quinn JF, Chung KA, Yearout D, Mata IF, Wan JY, Edwards KL, Montine TJ, Zabetian CP. Apo E4 increases risk for dementia in pure synucleinopathies. JAMA Neurol. 2013: 70(2); 223-8.

Cholerton BA, Zabetian CP, Quinn JF, Chung KA, Peterson A, Espay AJ, Revilla FJ, Devoto J, Watson GS, Hu SC, Edwards KL, Montine TJ, Leverenz JB. Pacific Northwest Udall center of excellence clinical consortium: study design and baseline cohort characteristics. J Parkinsons Dis. 2013;3(2):205-14. doi: 10.3233/JPD-130189. PMID: 23938350

Hill DA, Horick NK, Isaacs C, Domchek SM, Tomlinson GE, Lowery JT, Kinney AY, Berg JS, Edwards KL, Moorman PG, Plon SE, Strong LC, Ziogas A, Griffin CA, Kasten CH, Finkelstein DM. Long-term risk of medical conditions associated with breast cancer treatment. Breast Cancer Res Treat 2014;145:233-43. doi:10.1007/s107549-014-2928-4.
   
Research Center Genetic Epidemiology Research Unit
   
   
Link to this profile http://www.faculty.uci.edu/profile.cfm?faculty_id=6052
   
Last updated 04/21/2014