Lydia Su

Tu & Yuen Center for Functional Onco-Imaging, Radiation Oncology

M.S., University of California, Irvine, California

Ph.D., University of California, Irvine, California, Physics

Phone: (949) 824-4925

University of California, Irvine
164 Irvine Hall
Mail Code: 5020
Irvine, CA 92697

picture of Lydia  Su

Publications Last Five Years of Publications

Chan S, Chen JH, Agrawal G, Lin MQ, Mehta RS, Carpenter PM, Nalcioglu O, Su MY. Characterization of Pure Ductal Carcinoma in Situ on Dynamic Contrast-Enhanced MR Imaging: Do
Non-High Grade and High Grade Show Different Imaging Features? J. of Oncology, In press.

J-85. Chen JH, Mehta RS, Baek HM, Nie K, Liu H, Lin MQ, Yu HJ, Nalcioglu O, Su MY. Clinical characteristics and biomarkers of breast cancer associated with choline concentration measured by 1H MR spectroscopy. NMR in Biomedicine. In press.

Chen JH, Chang YC, Chang D, Wang YT, Nie K, Chang RF, Nalcioglu O, Su MY. Reduction of Breast Density Following Tamoxifen Treatment Evaluated by 3-D MRI: Preliminary Study. Magnetic Resonance Imaging, 2010 Sep 8. [Epub ahead of print]

Shih TC, Chen JH, Liu D, Nie K, Sun L, Lin M, Chang D, Nalcioglu O, Su MY. Computational simulation of breast compression based on segmented breast and fibroglandular tissues on magnetic resonance images. Phys Med Biol. 2010 Jul 21;55(14):4153-68.

Nie K, Su MY, Chau MK, Chan S, Nguyen H, Tseng T, Huang Y, McLaren CE, Nalcioglu O, Chen
JH. Age- and race-dependence of the fibroglandular breast density analyzed on 3D MRI. Med Phys.
2010 Jun;37(6):2770-6.

Chen JH, Mehta RS, Nalcioglu O, Su MY. MR imaging evaluation of non-inflammatory breast cancer with skin involvement following neoadjuvant chemotherapy. Ann Surg Oncol, 2010 Jul;17(7):1964-5.

Liao J, Zhu Y, Zhang M, Yuan H, Su MY, Yu X, Wang H. Microstructural white matter abnormalities independent of white matter lesion burden in amnestic mild cognitive impairment and early Alzheimer disease among Han Chinese elderly. Alzheimer Dis Assoc Disord. 2010 Jun 29. [Epub ahead of print]

Nalcioglu O, Su MY. Foreword (A Special Issue for Multimodal-Imaging). Technol Cancer Res Treat.
2010 Feb;9(1):1-4.

Mehta RS, Su MY. Continued Exploration of Bevacizumab in Breast Cancer. Ann Surg Oncol 2010
Feb;17(2): 655-656. (PMCID: 2816792)

Nie K, Chang D, Chen JH, Shih TC, Hsu CC, Nalcioglu O, Su MY. Impact of Skin Removal on Quantitative Measurement of Breast Density Using MRI. Med. Phys. 2010 Jan; 37(1):227-233. (PMCID: 2801738)

Nie K, Chen JH, Chang D, Hsu CC, Nalcioglu O, Su MY. Quantitative Analysis of Breast
Parenchymal Patterns Using 3D Fibroglandular Tissue Segmentation Based on MRI. Med. Phys. 2010
Jan; 37(1):217-226. (PMCID: 2801737)

Baek HM, Chen JH, Nalcioglu O, Su MY. Can MR Spectroscopy Provide Useful Information for Characterizing Estrogen Receptor Status in Breast Cancer? Ann Oncol. 2010 Mar;21(3):663-5. . (PMCID: 2826101)

Chen JH, Nie K, Bahri S, Hsu CC, Hsu FT, Shih HN, Lin M, Nalcioglu O, Su MY. Decrease in breast density in the contralateral normal breast of patients receiving neoadjuvant chemotherapy: MR imaging evaluation. Radiology 2010 Apr;255(1):44-52. (PMCID: 2843830)

Newell D, Nie K, Chen JH, Hsu CC, Yu HJ, Nalcioglu O, Su MY. Selection of Diagnostic Features on
Breast MRI to Differentiate between Malignant and Benign Lesions using Computed-Aided
Diagnosis: differences in lesions presenting as mass and non-mass-like enhancement. Eur. Radiol.
2010 Apr;20(4):771-81. (PMCID: 2835636)

Lin MQ, Chen JH, Nie K, Chang D, Nalcioglu O, Su MY. An Algorithm-Based Method for Detection of Blood Vessels in Breast MRI for Development of Computer-Aided Diagnosis. JMRI 2009 Oct; 30:817-824. (PMCID: 2789993)

Chen JH, Chang D, Nie K, Hsu FT, Shih HN, Hsu CC, Nalcioglu O, Su MY. Comparison of Breast Density in the Contralateral Normal Breast of Patients with Invasive and In-Situ Breast Cancer Measured on MRI. Ann Oncology 2009; 20: 1449-1450. (PMCID: 2733064)

Chen JH, Hsu FT, Shih HN, Hsu CC, Chang D, Nie K, Nalcioglu O, Su MY. Does Breast Density Show Difference in Patients with Estrogen Receptor Positive and Estrogen Receptor Negative Breast Cancer Measured on MRI? Ann Oncology 2009; 20:1447-1449. (PMCID: 2720819)

Bahri S, Chen JH, Mehta RS, Carpenter PM, Nie K, Kwon SY, Yu HJ, Nalcioglu O, Su MY. Residual Breast Cancer Diagnosed by MRI in Patients Receiving Neoadjuvant Chemotherapy with and without Bevacizumab. Ann Surg Oncol. 2009 Jun;16(6):1619-28. (PMCID: 2786305)

Carpenter PM, Chen WP, McLaren CE, Mendez A, Su MY. Angiogenesis in the Progression of Breast
Ductal Proliferations. International Journal of Surgical Pathology 2009 Apr 29.

J-67. McLaren CE, Chen WP, Nie K, Su MY. Prediction Of Malignant Breast Lesions From MRI Features: A Comparison Of Artificial Neural Network And Logistic Regression Techniques. Academic Radiology 2009 Jul;16(7):842-51.

Baek HM, Chen JH, Nie K, Yu HJ, Bahri S, Mehta RS, Nalcioglu O, Su MY. Predicting Pathological Response to Neoadjuvant Chemotherapy in Breast Cancer Using MRI and Quantitative Proton MR Spectroscopy. Radiology. 2009 Jun;251(3):653-62. (PMCID: 2687529)

Chen JH, Feig BA, Hsiang DJ, Butler JA, Mehta RS, Bahri S, Nalcioglu O, Su MY. Impact of MRI- Evaluated Neoadjuvant Chemotherapy Response on Change of Surgical Recommendation in Breast Cancer. Ann Surg. 2009 Mar;249(3):448-54. (PMCID: 2789298)

Agrawal G, Su MY, Nalcioglu O, Feig SA, Chen JH. Significance of Breast Lesion Descriptors in the
ACR BI-RADS MRI Lexicon. Cancer. 2009 Apr 1;115(7):1363-80. (PMCID: 2748779)

Nie K, Chen JH, Chan S, Chau MI, Yu HJ, Bahri S, Tseng T, Nalcioglu O, Su MY. Development of A Quantitative Method for Analysis of Breast Density Based on Three-dimensional Breast MRI. Med. Phys. 2008 Dec;35(12):5253-5262.

Chen JH, Mehta RS, Nalcioglu O, Su MY. Inflammatory Breast Cancer After Neoadjuvant Chemotherapy: Can Magnetic Resonance Imaging Precisely Diagnose the Final Pathological Response? Ann Surg Oncol. 2008 Dec;15(12):3609-13.

Nie K, Chen JH, Yu HJ, Chu Y, Nalcioglu O, Su MY. Quantitative Analysis of Lesion Morphology and Texture Features for Diagnostic Prediction in Breast MRI. Acad Radiol. 2008 Dec;15(12):1513-

Chen JH, Nalcioglu O, Su MY. Fibrocystic Change of the Breast Presenting as a Focal Lesion Mimicking Breast Cancer in MR Imaging. J Magn Reson Imaging. 2008 Dec;28(6):1499-505. (PMCID: 2597344)

Wang H, Golob E, Bert A, Nie K, Chu Y, Dick MB, Mandelkern M, Su MY. Alterations in Regional Brain Volume and Individual MRI-Guided Perfusion in Normal Control, Stable Mild Cognitive Impairment, and MCI-AD Converter. J. Geriatric Psychology and Neurology 2009 Mar;22(1):35-45.

Chen JH, Nalcioglu O, Su MY. MR Imaging Features of Breast Cancer Correlated with Hormonal
Receptors: Does Progesterone Receptor Matter? Ann Oncol. 2008 May;19(5):1024-6.

Chen JH, Liu H, Baek HM, Nalcioglu O, Su MY. MR Imaging Features of Fibrocystic Change of the
Breast. Magn Reson Imaging. Magn Reson Imaging. 2008 Nov;26(9):1207-14.

Baek HM, Chen JH, Nalcioglu O, Su MY. Proton MR Spectroscopy for Monitoring Early Treatment Response of Breast Cancer to Neoadjuvant Chemotherapy. Ann Oncol. 2008 May;19(5):1022-4.

Bahri S, Chen JH, Yu HJ, Kuzucan A, Nalcioglu O, Su MY. Can dynamic contrast-enhanced MRI (DCE-MRI) predict tumor recurrence and lymph node status in patients with breast cancer? Ann Oncol. 2008 Apr;19(4):822-4.

Baek HM, Chen JH, Nalcioglu O, Su MY. Choline as a Biomarker for Cell Proliferation: Do the Results from Proton MR Spectroscopy Show Difference between HER2/neu Positive and Negative Breast Cancers? Int J Cancer. 2008 Sep 1;123(5):1219-21.

Chen JH, Baek HM, Nalcioglu O, Su MY. Estrogen Receptor and Breast MR Imaging Features: A Correlation Study. J Magn Reson Imaging. 2008 Apr;27(4):825-33.

Baek HM, Chen JH, Yu HJ, Mehta RS, Nalcioglu O, Su MY. Detection of Choline Signal in Human Breast Lesions with Chemical-Shift Imaging. J Magn Reson Imaging. 2008 May;27(5):1114-21.

Baek HM, Yu H, Chen JH, Nalcioglu O, Su MY. Quantitative Correlation between 1H MR Spectroscopy and Dynamic Contrast-Enhanced MRI of Human Breast Cancer. Magn Reson Imaging.
2008 May;26(4):523-31.

Chen JH, Agrawal G, Feig B, Baek H-M, Carpenter PM, Nalcioglu O, Su MY. Triple Negative Breast
Cancer: MR Imaging Features in 29 Patients. Ann Oncol. 2007 Dec;18(12):2042-3.

Chen JH, Mehta RS, Carpenter PM, Nalcioglu O, Su MY. MRI in Predicting Pathological Response of
Triple Negative Breast Cancer Following Neoadjuvant Chemotherapy. J. Clin Oncol. 2007 Dec

Chen JH, Agrawal G, Carpenter P, Mehta RS, Nalcioglu O, Su MY. Pathological Axillary Lymph
Node Status in HER-2 Receptor Positive and Negative Breast Cancers. Ann Surg Oncol. 2008

Chen JH, Feig B, Agrawal G, Yu H, Carpenter PM, Mehta RS, Nalcioglu O, Su MY. MRI evaluation of pathologically complete response and residual tumors in breast cancer after neoadjuvant chemotherapy. Cancer. 2008 Jan 1;112(1):17-26.

Agrawal G, Chen JH, Baek HM, Hsiang D, Mehta RS, Nalcioglu O, Su MY. MRI features of breast cancer: a correlation study with HER-2 receptor. Ann Oncol. 2007 Nov;18(11):1903-4.

Yamamoto M, Mehta RS, Baick CH, Su MY, Lane KT, Butler JA, Hsiang DJ. The predictive value of sentinel lymph node biopsy in locally advanced breast cancer patients who have undergone neoadjuvant chemotherapy. Am Surg. 2007 Oct;73(10):977-80.

Hsiang DJ, Yamamoto M, Mehta RS, Su MY, Baick CH, Lane KT, Butler JA. Predicting nodal status using dynamic contrast-enhanced magnetic resonance imaging in patients with locally advanced breast cancer undergoing neoadjuvant chemotherapy with and without sequential trastuzumab. Arch Surg.
2007 Sep;142(9):855-61.

Yu H, Chen JH, Mehta RS, Nalcioglu O, Su MY. MRI Measurements of Tumor Size and Pharmacokinetic Parameters as Early Predictor of Response in Breast Cancer Patients Undergoing Neoadjuvant AC-Chemotherapy. J. Mag. Reson. Imag. 2007; 26(3):615-623.

Agrawal G, Chen JH, Baick CH, Chen AE, Mehta RS, Nalcioglu O, Su MY. Pathological complete response in triple negative poorly differentiated invasive ductal breast carcinoma detected during pregnancy. J Clin Oncol. 2007; 25(18):2618-2620.

Nishi RA, Liu H, Chu Y, Hamamura M, Su MY, Nalcioglu O, Anderson AJ. Behavioral, histological, and ex vivo magnetic resonance imaging assessment of graded contusion spinal cord injury in mice. J Neurotrauma. 2007 Apr;24(4):674-89.

Ray K, Wang H, Chu Y, Chen YF, Bert A, Hasso A, Su MY. Apparent Diffusion Coefficient in Regional Gray Matter and White Matter Structures Involved in Mild Cognitive Impairment. Radiology 2006; 241:197-205.

Wang H, Golob EJ, Su MY. Vascular volume and blood-brain barrier permeability measured by dynamic contrast enhanced MRI in hippocampus and cerebellum of patients with MCI and normal controls. J Magn Reson Imaging. 2006; 24(3):695-700.

Wang H, Su MY. Regional pattern of increased water diffusivity in hippocampus and corpus callosum in mild cognitive impairment. Dement Geriatr Cogn Disord. 2006; 22(3):223-229.

Chen YF, Wang H, Chu Y, Huang YC, Su MY. Regional quantification of white matter hyperintensity in normal aging, mild cognitive impairment, and Alzheimer's disease. Dement Geriatr Cogn Disord.
2006; 22(2):177-184.

Su MY, Baik HM, Yu HJ, Chen JH, Mehta RS, Nalcioglu O. Comparison of Choline and Pharmacokinetic Parameters in Breast Cancer Measured by MR Spectroscopic Imaging and Dynamic Contrast Enhanced MRI Technol Cancer Res Treat. 2006; Aug:5(4):401-410.

Chu Y, Su MY, Mandelkern M, Nalcioglu O. Resolution Improvement in Positron Emission Tomography Using Anatomical Magnetic Resonance Imaging. Technol Cancer Res Treat. 2006; Aug:5(4):311-318.

Baik HM, Su MY, Yu H, Mehta R, Nalcioglu O. Quantification of choline-containing compounds in malignant breast tumors by 1H MR spectroscopy using water as an internal reference at 1.5 T. MAGMA. 2006; May;19(2):96-104.

Tapp PD, Head K, Head E, Milgram NW, Muggenburg BA, Su MY. Application of an automated voxel-based morphometry technique to assess regional gray and white matter brain atrophy in a canine model of aging. Neuroimage. 2006 Jan 1;29(1):234-44.

Hsiang D, Shah N, Yu H, Su MY, Cerussi A, Butler J, Baick C, Mehta R, Nalcioglu O, Tromberg B.
Coregistration of dynamic contrast enhanced MRI and broadband diffuse optical spectroscopy for characterizing breast cancer. Technol Cancer Res Treat. 2005 Oct;4(5):549-58.

Su MY, Yu HJ, Carpenter PM, McLaren CE, Nalcioglu O. Pharmacokinetic parameters analyzed from
MR contrast enhancement kinetics of multiple malignant and benign breast lesions detected in the same patients. Technol Cancer Res Treat. 2005 Jun;4(3):255-63.

Tapp PD, Chu Y, Araujo JA, Chiou JY, Head E, Milgram NW, Su MY. Effects of scopolamine challenge on regional cerebral blood volume. A pharmacological model to validate the use of contrast enhanced magnetic resonance imaging to assess cerebral blood volume in a canine model of aging. Prog Neuropsychopharmacol Biol Psychiatry. 2005 Mar;29(3):399-406.

Su MY, Tapp PD, Vu L, Chen YF, Chu Y, Muggenburg B, Chiou JY, Chen C, Wang J, Bracco C, Head E. A longitudinal study of brain morphometrics using serial magnetic resonance imaging analysis in a canine model of aging. Prog Neuropsychopharmacol Biol Psychiatry. 2005
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Last updated 12/10/2010