Daniela BotaAssistant Professor, Neurology Medical Director, Neuro-Oncology Program |
|
|
Research Interests |
Neuro-oncology | |
| URL | Brain Tumor Program | |
| Publications |
Daniela A Bota, Henry S. Friedman Interstitial Chemotherapy with Biodegradable BCNU (Gliadel) Wafers in the Treatment of Malignant Gliomas Therapeutics and Clinical Risk Management, 3(5): 707-715. 2007 D. A. Bota, MD, PhD; G. Gronseth, MD; M. Glantz, MD. Practice Parameter: Radiation therapy and Chemotherapy for Low-Grade Glioma (An Evidence-Based Review). Report of the Quality Standards Subcommittee of the American Academy of Neurology (accepted for publication) Dafer, R.M., Bota, D.A., Perez, M., Smith, SM. Acute Methotrexate Neurotoxicity with Choreiform Movements and Focal Deficits: A Case Report. South Med J. 102 (10):1071-4, October 2009 Bota RG, M.D., Munro JS, M.D., Ricci WF, M.D., Bota DA, M.D., Ph.D. “Dynamics of insight in the prodrome of schizophrenia” CNS Spectrum 11(5):355-62. 2006 Bota RG, M.D., Munro JS, M.D., Ricci WF, M.D., Bota DA, M.D., Ph.D. “Dynamics of insight in the prodrome of schizophrenia” CNS Spectrum 11(5):355-62. 2006 Bota, D.A., Ngo, J.K., and Davies, K.J.A., 2005. Downregulation of the Human Lon Protease Impairs Mitochondrial Structure, Function and Replication, and Causes Cell Death. Free Radic. Biol. Med. 38, 665-77 Bota, D.A., and Davies, K.J.A., 2002. Lon protease preferentially degrades oxidized mitochondrial aconitase by an ATP-stimulated mechanism. Nature Cell Biology 4, 674-680. Bota, D.A., Van Remmen, H. and Davies, K.J.A., 2002. Modulation of Lon Protease Activity and Aconitase Turnover during Aging and Oxidative Stress. FEBS Letters 532, 103-106. Bota, D.A., 2002. Importance of the Lon protease in Mitochondrial Protein Turnover and Cellular Bioenergetics during Oxidative Stress and Aging. PhD Dissertation Defense, University of Southern California, Department of Molecular and Computational Biology Bota, D. A., and Davies, K.J.A., 2001. Protein Degradation in Mitochondria: Implications for Oxidative Stress, Aging and Disease. A novel etiological classification of mitochondrial proteolysis disorders. Mitochondrion 1, 33-49. |
|
| Grants | ASC Seed Award | |
| National Institutes of Health (NIH), "The Mechanisms of Chemotherapy Induced Cognitive Defects" 2011-2012 | ||
|
Professional Societies |
Society of Neuro-Oncology American Society of Clinical Oncology American Academy of Neurology |
|
| Link to this profile | http://www.faculty.uci.edu/profile.cfm?faculty_id=5555 | |
| Last updated | 10/09/2012 | |