Suzanne BlumAssistant Professor, Chemistry |
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| URL | Blum Research Group Website | |
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Academic Distinctions |
Thieme Synlett-Synthesis Journal Award, 2009 NSF CAREER Award, 2008 UC-Berkeley Teaching Effectiveness Award, 2005 UC-Berkeley Outstanding Graduate Instructor, 2004 NSF Graduate Fellow, 2000-2003 Hertz Fellowship Grant, 2000 |
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| Appointments | NIH Postdoctoral Fellow, Harvard Medical School, 2004-2006 | |
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Research Abstract |
Research in the Blum Group focuses on the development of new catalysts and metal-mediated reactions with applications in organic synthesis. We are also developing single-molecule techniques to image catalytic reactions at individual transition metal centers. These single-molecule techniques are part of a big-picture, ground-breaking project to change the way chemists think about studying chemical reaction mechanisms: by actually watching reactions live, one molecule at a time. Ultimately, we are interested in learning about the reactivity of transition metals such that those lessons can be applied broadly to the development of new methods. These studies provide an excellent platform for testing mechanistic hypotheses and for building new fundamental understanding of metal-based reactivity. | |
| Publications | (10) Lim, S. G.; Blum, S. A. "A General Fluorescence Resonance Energy Transfer (FRET) Method for Observation and Quantification of Organometallic Complexes under Reaction Conditions." Organometallics 2009, 28, 4643. | |
| (9) Shi, Y.; Ramgren, S. D.; Blum, S. A. "Palladium-Catalyzed Carboauration of Alkynes and Palladium/Gold Cross-Coupling." Organometallics 2009, 28, 1275. | ||
| (8) Canham, S. M.; Bass, J. Y.; Navarro, O.; Lim, S.-G.; Das, N.; Blum, S. A. "Toward the Single-Molecule Investigation of Organometallic Reaction Mechanisms: Single-Molecule Imaging of Fluorophore-Tagged Palladium(II) Complexes." Organometallics 2008, 27, 2172. | ||
| (7) Shi, Y.; Peterson, S. M.; Haberaecker, W. W., III; Blum, S. A. "Alkynes as Stille Reaction Pseudohalides: Synthesis of Tri- and Tetra-Substituted Olefins." J. Am. Chem. Soc. 2008, 130, 2168. | ||
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(6) Lalic, G.; Blum, S. A.; Bergman, R. G. "Zirconium-Mediated SN2' Substitution of Allylic Ethers: Regio- and Stereospecific Formation of Protected Allylic Amines." J. Am. Chem. Soc. 2005, 127, 16790-16791. (5) Blum, S. A.; Rivera, V. A.; Ruck, R. T.; Michael, F. E.; Bergman, R. G. "Synthetic and Mechanistic Studies of Strained Heterocycle Opening Reactions Mediated by Zirconium(IV) Imido Complexes." Organometallics 2005, 24, 1647-1659. (4) Blum, S. A.; Bergman, R. G. "Nitro and Nitroso Metathesis Reactions with Monomeric Zirconium Imido Complexes." Organometallics 2004, 23, 4003-4005. (3) Blum, S. A.; Tan, K. L.; Bergman, R. G. "The Application of Physical Organic Methods to the Investigation of Organometallic Reaction Mechanisms." J. Org. Chem. 2003, 68, 4127-4137. (2) Blum, S. A.; Walsh, P. J.; Bergman, R. G. "Epoxide-Opening and Group-Transfer Reactions Mediated by Monomeric Zirconium Imido Complexes." J. Am. Chem. Soc. 2003, 125, 14276-14277. (1) Blum, S. A.; Bergman, R. G.; Ellman, J. A. "Enantioselective Oxidation of Di-tert-Butyl Disulfide with a Vanadium Catalyst: Progress Toward Mechanism Elucidation." J. Org. Chem. 2003, 68, 150-155. |
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| Link to this profile | http://www.faculty.uci.edu/profile.cfm?faculty_id=5378 | |
| Last updated | 09/15/2009 | |