David Christian LyonAssistant Professor, Anatomy & Neurobiology |
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Research Interests |
Visual Cortex, Pulvinar Nucleus, Orientation Selectivity, Optical Imaging, Single Cell Electroporation, Neurophysiology, Neuroanatomy | |
| URL | Department Website | |
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Academic Distinctions |
Krieg Cortical Scholar Award, Cajal Club, 2003 Krieg Cortical Explorer Award, Cajal Club, 2007 |
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| Appointments |
Postdoctoral Fellow, MIT Postdoctoral Fellow, Salk Institute |
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Research Abstract |
The lab relates structure to function in the mammalian visual cortex and thalamus using a variety of techniques - from intrinsic signal imaging to genetically targeted viral tracing. We are interested in the number and organization of cortical areas, how modules within each area derive their functional characteristics, and the detailed circuitry underlying sensory capabilities of a single neuron. Our current focus is on mechanisms involved in orientation selectivity in the neocortex. In particular, we are studying how inputs from beyond a primary visual cortex cell's classical receptive field contribute to the extra-classical surround. |
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| Publications |
Kaas JH and Lyon DC (2007) Pulvinar contributions to the dorsal and ventral streams of visual processing in primates. Brain Research Reviews, Special Issue on Golgi and Cajal. 55:285-296. |
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| Wickersham IR, Lyon DC, Barnard RJ, Mori T, Finke S, Conzelmann KK, Young JA, Callaway EM (2007) Monosynaptic restriction of transsynaptic tracing from single, genetically targeted neurons. Neuron. 53:639-647. | ||
| Lyon DC (2006) The evolution of visual cortex and visual systems. In: The Evolution of the Nervous System in Mammals. Eds, LA Krubitzer and JH Kaas. Elsevier, London. | ||
| Nassi JJ*, Lyon DC* and Callaway EM (2006) The parvocellular LGN provides a robust disynaptic input to the visual motion area MT. Neuron. 50:319-327. *Co-First Authors | ||
| Mariño J, Schummers J, Lyon DC, Schwabe L, Beck O, Wiesing P, Obermayer K and Sur M (2005) Invariant computations in local cortical networks with balanced excitation and inhibition. Nature Neuroscience. 8:194-201. | ||
| Collins CE, Lyon DC and Kaas JH (2005) Distribution across cortical areas of neurons projecting to the superior colliculus in New World monkeys. Anatomical Record. 285A:619-627. | ||
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Lyon DC, Jain N and Kaas JH (2003a) The visual pulvinar in tree shrews I. Multiple subdivisions revealed through acetylcholinesterase and Cat-301 chemoarchitecture. Journal of Comparative Neurology. 467:593-606. |
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Lyon DC, Jain N and Kaas JH (2003b) The visual pulvinar in tree shrews II. Projections of four nuclei to areas of visual cortex. Journal of Comparative Neurology. 467:607-627. |
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| Collins CE, Lyon DC and Kaas JH (2003) Responses of neurons in MT after longstanding lesions of V1 in adult New World monkeys. Journal of Neuroscience. 23(6): 2251-2264. | ||
| Lyon DC, Xu X, Casagrande V, Stephansic J, Shima D and Kaas JH (2002) Optical imaging reveals retinotopic organization of dorsal V3 in New World owl monkeys. Proceedings of the National Academy of Sciences, USA. 99(24):15735-15742. | ||
| Lyon DC and Kaas JH (2002) Evidence for a modified V3 with dorsal and ventral halves in macaque monkeys. Neuron. 33(3):453-461. | ||
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Lyon DC and Kaas JH (2002) Connectional evidence for dorsal and ventral V3, and other extrastriate areas in the prosimian primate, Galago garnetti. Brain, Behavior and Evolution. 59(3):114-129. |
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Qi H-X, Lyon DC and Kaas JH (2002) Topography, connections and architecture of the parietal ventral somatosensory area in marmosets. Journal of Comparative Neurology. 443(2):168-182. |
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| Lyon DC and Kaas JH (2002) Evidence from V1 connections for both dorsal and ventral subdivisions of V3 in three species of New World monkeys. Journal of Comparative Neurology. 449(3):281-297. | ||
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Kaas JH and Lyon DC (2001) Visual cortex organization in primates: Theories of V3 and adjoining visual areas. Progress in Brain Research. 134:285-295. |
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| Lyon DC and Kaas JH (2001) Connectional and architectonic evidence for dorsal and ventral V3, and area DM in marmoset monkeys. Journal of Neuroscience. 21(1):249-261. | ||
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Catania KC, Lyon DC, Mock OB and Kaas JH (1999) Cortical organization in shrews: Evidence from five species. Journal of Comparative Neurology. 410(1):55-72. |
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| Lyon DC, Jain N and Kaas JH (1998) Cortical connections of striate and extrastriate visual areas in tree shrews. Journal of Comparative Neurology. 401(1):109-128. | ||
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Professional Societies |
Society for Neuroscience Vision Sciences Society |
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| Research Center | Center for Cognitive Neuroscience | |
| Link to this profile | http://www.faculty.uci.edu/profile.cfm?faculty_id=5351 | |
| Last updated | 04/17/2008 | |