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Robert M. Corn

Professor, Chemistry
School of Physical Sciences

Ph.D., University of California, Berkeley, 1983, Chemistry

B.A., University of California, San Diego, 1978, Chemistry

Phone: (949) 824-1746
Fax: (949) 824-8571
Email: rcorn@uci.edu

University of California, Irvine
2139 Natural Sciences 2
Mail Code: 2025
Irvine, CA 92697

picture of Robert M. Corn

Surface Chemistry, Surface Spectroscopy, Metal and Magnetic Nanoparticle Materials, Biosensors, DNA at Surfaces, SPR, FTIR, Diffraction
URL corninfo.ps.uci.edu
2007 Pittsburgh Spectroscopy Award
2007 ACS Division of Analytical Chemistry Award in Spectrochemical Analysis
2007 AAAS Fellow
Appointments Visiting Scientist at the IBM Research Laboratory in San Jose, California, 1983-1984
Professor Corn's area of expertise is the study of chemistry at condensed phase interfaces. Specific areas of research include the use of surface plasmon resonance (SPR) to monitor biopolymer adsorption, the chemical modification of surfaces with self-assembled monolayers for the creation of adsorption-based biosensors, the characterization of molecular monolayers at metal surfaces by polarization-modulation FTIR reflection absorption spectroscopy (PM-FTIRRAS) and optical second harmonic generation (SHG) measurements of molecular orientation, the surface modification of gold nanoparticles, and the synthesis of magnetic nanoparticles for high frequency inductor applications. Prof. Corn also has ongoing research projects in the implementation of DNA computing algorithms at surfaces, and the fabrication of multilayer polyelectrolyte films for ion transport applications.
Available Technologies
Publications Mana Toma, Gabriel Loget and Robert M. Corn, "Fabrication of Broadband Antireflective Plasmonic Gold Nanocone Arrays on Flexible Polymer Films", Nano Lett., 13 ASAP article (2013).
  Gabriel Loget, Jennifer B. Wood, Kyunghee Cho, Aaron R. Halpern and Robert M. Corn, "Electrodeposition of Polydopamine Thin Films for DNA Patterning and Microarrays", Analytical Chemistry, 85 9991-9995 (2013).
  Jennifer B. Wood, Megan W. Szyndler, Aaron R. Halpern, Kyunghee Cho and Robert M. Corn, "Fabrication of DNA Microarrays on Polydopamine-Modified Gold Thin Films for SPR Imaging Measurements", Langmuir, 29 10868-10873 (2013).
  Megan W. Szyndler, Kenneth F. Haynes, Michael F. Potter, Robert M. Corn and Catherine Loudon, "Entrapment of bed bugs by leaf trichomes inspires microfabrication of biomimetic surfaces", J. R. Soc. Interface, 10 20130174 (2013).
  Aaron R. Halpern and Robert M. Corn, "Lithographically Patterned Electrodeposition of Gold, Silver, and Nickel Nanoring Arrays with Widely Tunable Near-Infrared Plasmonic Resonances,"ACS Nano, 7 1755-1762 (2013).
  Yulin Chen and Robert M. Corn, "DNAzyme Footprinting: Detecting Protein-Aptamer Complexation on Surfaces by Blocking DNAzyme Cleavage Activity", J. Am. Chem. Soc., 135 2072-2075 (2013).
  Megan W. Szyndler and Robert M. Corn, "Self-Assembly of Flux-Closure Polygons from Magnetite Nanocubes" J. Phys. Chem. Lett., 3 2320-2325 (2012).
  David W. Marsh, Megan W. Szyndler, Robert M. Corn and A. S. Borovik, "Preparation of monolithic superparamagnetic nanoparticle-polymer composites using a polymerizable acetylacetonate and magnetite nanoparticles" Polymer Chem., 3 2852-2856 (2012).
  Ting H. Seefeld, Aaron R. Halpern and Robert M. Corn, "On-Chip Synthesis of Protein Microarrays from DNA Microarrays Via Coupled In Vitro Transcription and Translation for Surface Plasmon Resonance Imaging Biosensor Applications" J. Am. Chem. Soc., 134 12358-12361 (2012).
  Aaron R. Halpern, Keith C. Donavan, Reginald M. Penner and Robert M. Corn, "Wafer-Scale Fabrication of Nanofluidic Arrays and Networks Using Nanoimprint Lithography and LPNE Gold Nanowire Masters," Analytical Chemistry, 84 5053-5058 (2012).
  Yong Wang, Xuejun Liu, Aaron R. Halpern, Kyunghee Cho, Robert M. Corn, and Eric O. Potma, "Wide-field, surface-sensitive four-wave mixing microscopy of nanostructures," Applied Optics, 51 3305-3312 (2012).
  Yulin Chen, Kohei Nakamoto, Osamu Niwa and Robert M. Corn, "On-Chip Synthesis of RNA Aptamer Microarrays for Multiplexed Protein Biosensing with SPR Imaging Measurements," Langmuir, 28 8281-8285 (2012).
  Yuka Okabe, Yulin Chen, Rishi Purohita, Robert M. Corn and Abraham P. Lee, "Piezoelectrically Driven Vertical Cavity Acoustic Transducers for the Convective Transport and Rapid Detection of DNA and Protein Binding to DNA Microarrays with SPR Imaging-A Parametric Study," Biosensors and Bioelectronics, 35 37-43 (2012).
  Wenjuan Zhou, Aaron R. Halpern, Ting H. Seefeld and Robert M. Corn, "Near Infrared SPR Phase Imaging and Nanoparticle-Enhanced SPR Phase Imaging for Ultrasensitive Protein and DNA Biosensing with Oligonucleotide and Aptamer Microarrays," Analytical Chem., 84 440-445 (2012).
  Yin Han and Robert M. Corn, "Characterization and Application of Surface Plasmon-Enhanced Optical Diffraction from Electrodeposited Gold Nanowire Arrays," J. Phys. Chem. Lett., 2 1601-1606 (2011).
  Wen-Juan Zhou, Yulin Chen and Robert M. Corn, "Ultrasensitive Microarray Detection of Short RNA Sequences with Enzymatically Modified Nanoparticles and SPR Imaging Measurements," Analytical Chem., 83 3897-3902 (2011).
  Iuliana E. Sendroiu, Lida K. Gifford, Andrej Lupták, and Robert M. Corn, "Ultrasensitive DNA Microarray Biosensing via in situ RNA Transcription-Based Amplification and Nanoparticle-Enhanced SPR Imaging," J. Am. Chem. Soc., 133 4271–4273 (2011).
  Aaron R. Halpern, Yulin Chen, Robert M. Corn, and Donghyun Kim, "Surface Plasmon Resonance Phase Imaging Measurements of Patterned Monolayers and DNA Adsorption onto Microarrays," Analytical Chem., 83 2801–2806 (2011).
  Ting H. Seefeld, Wen-Juan Zhou, and Robert M. Corn, "Rapid Microarray Detection of DNA and Proteins in Microliter Volumes with SPR Imaging Measurements," Langmuir, 27 6534-6540 (2011).
  Lida K. Gifford, Iuliana E. Sendroiu, Robert M. Corn, and Andrej Luptak, "Attomole Detection of Mesophilic DNA Polymerase Products by Nanoparticle-Enhanced Surface Plasmon Resonance Imaging on Glassified Gold Surfaces," J. Am. Chem. Soc., 132 9265-9267 (2010).
  Yulin Chen, Sheng-Chin Kung, David Taggart, Aaron R. Halpern, Reginald Penner, and Robert M. Corn, "Fabricating Nanoscale DNA Patterns with Gold Nanowires," Analytical Chem., 82 3365-3370 (2010).
  Yulin Chen, Anh Nguyen, Lifang Niu and Robert M. Corn, "Fabrication of DNA Microarrays with poly-L-Glutamic Acid Monolayers on Gold Substrates for SPR Imaging Measurements," Langmuir, 25 5054-5060 (2009).
  Aaron R. Halpern, Naoya Nishi, Jia Wen, Fan Yang, Chengxiang Xiang, Reginald Penner, and Robert M. Corn, "Characterization of Electrodeposited Gold and Palladium Nanowire Gratings with Optical Diffraction Measurements," Analytical Chem., 81 5585-5592 (2009).
  Iuliana E. Sendroiu, Megan E. Warner, and Robert M. Corn, "Fabrication of silica-coated gold nanorods functionalized with DNA for enhanced SPR imaging biosensing applications," Langmuir, 25 11282-11284 (2009).
Sigma Xi
American Chemical Society
Society for Applied Spectroscopy
International Society of Electrochemistry
Other Experience Professor
University of Wisconsin 1985—2004

Joined UCI Faculty in 2004

Graduate Programs Chemistry

Biomedical Engineering

Link to this profile http://www.faculty.uci.edu/profile.cfm?faculty_id=5123
Last updated 12/05/2013