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David K. Imagawa

Professor of Clinical Surgery, Surgery
School of Medicine

Chief Division of Hepatobiliary and Pancreas Surgery/Islet Cell Transplantation

Suzanne Dykema Endowed Chair in Pancreatic Cancer


M.D., The John Hopkins Medical School


Ph.D. Pharmacology, Johns Hopkins Medical School

Phone: (714) 456-3884
Fax: (714) 456-3487
Email: dkimagaw@uci.edu

University of California, Irvine
333 City Blvd West, Suite 1205
Orange, CA 92868

picture of David K. Imagawa

Research
Interests
Liver cancer, pancreatic cancer, bile duct tumor, pathogenesis of chronic rejection, post transplant hyperlipidemia, gene therapy for immunosuppression, reperfusion injury in transplantation, islet cell transplantation
   
URL www.ucihs.uci.edu/com/surgery/index.html
   
Academic
Distinctions
John Connolly Award Winner
2002, 2005, 2009
   
Appointments Chief, Division of Transplantation
   
Research
Abstract
Research, Clinical Activities, Community Outreach:
Liver and pancreatic diseases, bile duct and pancreatic tumor resections, bile duct injuries, biliary reconstruction, minimal invasive treatment of advanced liver tumors, laparascopic, ultrasound guided radiofrequency ablation, biliary reconstruction, pathogenesis of chronic rejection, liver cancer, hepatocellular carcinoma, liver tumor, post transplant hyperlipidemia, clinical trials of novel chemotherapeutic agents, Therasphere, Cirtex, Metabasis, gene therapy for immunosuppression, reperfusion injury in transplantation, islet cell transplantation for complicated Diabetes Mellitus Type I, mechanism of immunomodulation, hepatitis screening, organ donation
   
Publications Manuscripts

1. J.D. Boyd; C.S. Foote; D.K. Imagawa. 1980. Synthesis of 1,2:3,4-diepoxides by Catalyzed Rearrangement of 1,4-Endoperoxides. J Am Chem Soc. 102:3641.

2. E. Kho; D.K. Imagawa; M. Rohmer; Y. Kashman; C. Djerassi. 1981. Isolation and Structure Elucidation of Conicasterol and Theonellasterol, Two new 4-methylene Sterols from Red Sea Sponges Theonella conica and Theonellaswinhoei. J Org Chem. 46:1836.

3. D.K. Imagawa; N.E. Osifchin; W.A. Paznekas; M.L. Shin; M.M. Mayer. 1983. Consequences of Cell Membrane Attack by Complement: Release of Arachidonate and Formation of Inflammatory Derivatives. Proc Natl Acad Sci U S A. 1983 November; 80(21): 6647–51.

4. M.M. Mayer; D.K. Imagawa; L.E. Ramm; M.B. Whitlow. 1983. Membrane Attack by Complement and its Consequences. Progress in Immunology V. 427:444.

5. C.H. Shatney; R.M. Cohen; M.R. Cohen; D.K. Imagawa. 1985. Endogenous Opiod Activity in Clinical Hemorrhagic Shock. Surg Gynecol Obstet. 160:547.

6. B.P. Morgan; D.K. Imagawa; J.R. Dankert; L.E. Ramm. 1986. Complement Lysis of U937, a Nucleated Mammalian Cell Line, by Complement Proteins C5b-8. J Immunol. 136:3402.

7. D.K. Imagawa; N.E. Osifchin; L.E. Ramm; P.G. Koga; C.H. Hammer; H.S. Shin; and M.M. Mayer. 1986. Release of Arachidonic Acid and Formation of Oxygenated Derivatives Following Complement Attack on Macrophages: Role of Channel Formation. J Immunol. 136:4637.

8. B.R. Rosengard; T.S. Hall; D.K. Imagawa; K. Ueda; W.A. Baumgartner; M. Borkon; R.L. Smith; G.M. Hutchins; B.A. Reitz. 1986. Hyperacute Rejection of Cardiac Xenografts: Two New Models Showing Different Pathogenesis. Surgical Forum. XXXVI:361.

9. Y. Shirazi; D.K. Imagawa; M. Shin. 1987. Release of Arachidonic Acid- derived Inflammatory Mediators from Sublethally-injured Oligodendrocytes by Terminal Complement Proteins, C5b-9. I Neurochem. 48:271.

10. D.K. Imagawa; S.E. Barbour; B.P. Morgan; T.M. Wright; H.S. Shin; L.E. Ramm. 1987. Role of Complement C9 and Calcium in the Generation of Arachidonic Acid and its Metabolites from Rat Polymorphonuclear Leukocytes. Mol Immunol. 24: 1263.

11. K.M Olthoff; J.M. Millis; D.K. Imagawa; et al. 1990. Comparison of University of Wisconsin solution vs. Euro-Collins solution for cold preservation of liver grafts. Transplantation. 49:284.

12. D.K. Imagawa; J.M. Millis; K.M. Olthoff; A. Baquerizo; R.W. Busuttil. 1990. Anti-tumor Necrosis Factor Antibody Therapy Enhances Cardiac Allograft Survival in Rats. J Surg Research. 48:345.

13. D.K. Imagawa; J. M. Millis; K. M. Olthoff; L.J. Derus; D. Chia; L.R. Sugich; M. Ozawa; R.A. Dempsey; Y. Iwaki; P.J. Levy; et al. The Role of Tumor Necrosis Factor in Allograft Rejection. I. Elevated Levels of Tumor Necrosis Factor-Alpha Predict Rejection Following Orthotopic Liver Transplantation. Transplantation. 1990 Aug;50(2):219-25.

14. D.K. Imagawa; J.M Millis; K.M. Olthoff; et al. 1990. The Role of Tumor Necrosis Factor in Allograft Rejection. II. Antibody Therapy against Tumor Necrosis Factor-Alpha and Lymphotoxin Enhances Cardiac Allograft Survival in Rats. Transplantation. 50:189.

15. A. Bacquerizo; N. Kamada; J. Hart; J. M. Millis; C. Pera; K. Olthoff; D.K. Imagawa; M. Orloff; R.W. Busuttil. 1990. Influence of Number and Timing of Serum Transfusions on Liver Allograft Survival in Rats. Transplant Proc. 22:2020.

16. K. Teramoto; A. Baquerizo; D.K. Imagawa; K.M. Olthoff; R.A. Dempsey; R.W. Busuttil. 1990. Prolongation of Hepatic Allograft Survival in Rat Recipients treated with Anti-Lymphotoxin Antibody. Transplant Proc. 23:602.

17. D.K. Imagawa; J.M. Millis; P. Seu; K.M. Olthoff; L. Hart; E. Wasef; R.A. Dempsey; S. Stephens; R.W. Busuttil. 1991. The Role of Tumor Necrosis Factor in Allograft Rejection. III. Anti-TNF Antibody Therapy Prolongs Allograft Survival in Rats with Acute Rejection. Transplantation. 51:57.

18. P. Seu; D.K. Imagawa; K. M. Olthoff; J.M. Millis; J. Hart; E. Wasef; R.A. Dempsey; R.W. Busuttil. 1991. Effects of Tumor Necrosis Factor (TNF) and Immunotherapy Directed Against TNF on Rat Cardiac Transplants. Transplant Proc. 23:233.

19. P. Seu; D.K. Imagawa; K.M. Olthoff; E.M. Wasef; R.A. Dempsey; R.W. Busuttil. 1991. Monoclonal Anti-tumor Necrosis Factor-alpha Antibody Treatment of Rat Cardiac Allografts: Synergism with Low-Dose Cyclosporine and Immunohistological Studies. J Surg Research. 50:520.

20. K.M. Olthoff; E. Wasef; P. Seu; D.K. Imagawa; J.A. Freischlag; J. Hart; R.W. Busuttil. 1991. PGE1 Reduces Injury in Hepatic Allografts Following Preservation. J Surg Research. 50:595.

21. Y. Sameshima; D. Chia; P.I. Terasaki; D.K. Imagawa; R.W. Busuttil. 1992. Appearance of the Tumor Marker CA 19-9 in Liver Transplant Patients During Rejection Episodes. Transplantation. 53:580.

22. D.K. Imagawa; K. Noguchi; Y. Iwaki; R.W. Busuttil. 1992. Hyperacute Rejection Following ABO-Compatible Orthotopic Liver Transplantation: A Case Report. Transplantation. 54: 1114.

23. M. Shiraishi; A. Shaked; C. Yasunaga; Y. Hasuike; D.K. Imagawa; R.W. Busuttil. 1993. Monoclonal Anti-Tumor Necrosis Factor-alpha Antibody Suppresses Rejection, But Enhance Infectious Complications in Rat Liver Allograft Recipients. Transplant Proc. 25 (1 Pt 1):128.

24. K. Ogura; H. Koyama; J. Chia; D.K. Imagawa; P.I. Terasaki; R.W. Busuttil. 1994. High One Month Liver Graft Failure Rates in Flow Cytometry Crossmatch Positive Patients. Clinical Transplant 8:111.

25. D.K. Imagawa; J. M Lien; M.C. Dugan; R. K. Tompkins. 1994. Angiomyolipoma of the Liver Presenting in Pregnancy. American Surgeon. 60:824.

26. F.C. Brunicardi; Oh Y.; Shevlin L.; E. Suh; R. Kleinman; E. Stein; G. Lipaz; D. V. Plant; D. K. Imagawa; H. R. Fetterman; et al. 1994. Laser Destruction of Human Nonislet Pancreatic Tissue. Transplantation Proceedings, 26:3354.

27. O. Jurim; M. Csete; H.A. Gelabert; J.M. Millis; K. Olthoff; D.K. Imagawa; A. Shaked; S.V. McDiarmid; R.W. Busuttil. 1995. Reduced-Size Grafts - The Solution for Hepatic Artery Thrombosis After Pediatric Liver Transplantation? 1995. J Ped Surg. 30:53.

28. M. Millis; D.K. Imagawa; K. Olthoff; P. Martin; A. Gomes; A. Shaked; H. Yersiz; K. Drazan; L. Goldstein; R. Busuttil. 1995. TIPS: Impact on Liver Transplantation. Transplant Proc. 27:1252.

29. K.M. Olthoff; M.H. Rosove; C.R. Shackleton; D.K. Imagawa; D. Farmer; P. Northcross; A.L. Pakrasi; P. Martin; L.I. Goldstein; A. Shaked; R.W. Busuttil. 1995. Adjuvant Chemotherapy Improves Survival Following Liver Transplantation for Hepatocellular Carcinoma. Ann Surg. 221:734.

30. O. Jurim; C.R. Shackleton; A. Shaked; C.V. McDiarmid; A. Maxfield; J.M. Millis; K.M. Olthoff; D.K. Imagawa; R.W. Busuttil. 1995. Living Donor Liver Transplantation at UCLA. Am J Surg. 169:529.

31. S. Moldovan; A. Atiya; T.E. Adrian; R.M. Kleinman; K. Lloyd; K. Olthoff; D.K. Imagawa; L. Shevlin, D. Coy; J. Walsh; F.C. Brunicardi. 1995. Somatostatin Inhibits B Cell Secretion Via A Subtype-2 Somatostatin Receptor in the Isolated Perfused Human Pancreas. Archives of Surgery. J. Surgical Research 59:85.

32. H. Yersiz; A. Shaked; K. Olthoff; D.K. Imagawa; C. Shackleton; P. Martin; R.W. Busuttil. 1995. Correlation Between Donor Age and the Pattern of Liver Graft Recovery after Transplantation. Transplantation, 60:790.

33. C.R. Shackleton; P. Martin; J. Melinek; L. Stothers; J.M. Millis; K.M. Olthoff; D.K. Imagawa; M. Kinkhabwala; S. Rudich; P. Seu; A. Shaked; S.V. McDiarmid; L.I. Goldstein; R.W. Busuttil. 1995. Lack of Correlation Between the Magnitude of Preservation Injury and the Incidence of Acute Rejection, Need for OKT3 or Conversion to FK506 in Cyclosporine Treated Primary Liver Allograft Recipients. Transplantation, 60:554.

34. D.G. Farmer; A. Shaked; K.M. Olthoff; D.K. Imagawa; J.M. Millis; R.W. Busuttil. 1995. Evaluation, Operative Management, and Outcome after Liver Transplantation in Children with Biliary Atresia and Situs Inversuss. Ann. Surg. 222:47.

35. D.J. Winston; D.K. Imagawa; C.D. Holt; F. Kaldas; A. Shaked; R.W. Busuttil. 1995. Long-Term Ganciclovir Prophylaxis Eliminates Serious Cytomegalovirus Disease in Liver Transplant patients Receiving OKT3 Therapy for Rejection. Transplantation, 60:1357.

36. K. Drazan; A. Shaked; K. M. Olthoff; D.K. Imagawa; O. Jurim; K. Kial; C. Schackleton; R. Busuttil. 1996. Etiology and Management of Symptomatic Adult Hepatic Artery Thrombosis After Orthotopic LiverTransplantation (OLT). 1996. American Surgeon, 62:237.

37. D.K. Imagawa; K.M. Olthoff; H. Yersiz; C.R. Shackleton; S.D. Colquhoun; A. Shaked; R.W, Busuttil. Rapid En Bloc Technique for Pancreas-Liver Procurement. Improved Early Liver Function. Transplantation. 1996 Jun 15;61(11):1605-9.

38. P. Seu; D.K. Imagawa; K.M. Olthoff; H. Yersiz; T.J. Rosenthal; C.A. Sellers; G. Gentler; M. Abe; D. Green; C.R. Shackleton; S.M. Rudich; M. Kinkhabwala; J.A. Goss; J.S. Markowitz; R.W. Busuttil. 1996. A Prospective Study On The Reliability and Cost Effectiveness of Preoperative Ultrasound Screening Of The “Marginal” Liver Donor. Transplantation. 62:129.

39. D.K. Imagawa; S. Dawson III; C.D. Holt; P.S. Kirk; F.M. Kaldas; C.R. Shackelton; P. Seu; S.M. Rudich; M.M. Kinkhabwala; P. Martin; L.I. Goldstein; N.G.B. Murray; P.J. Teraski, R.W. Busuttil. Hyperlipidemia after liver transplantation: natural history and treatment with the hydroxy-methylglutaryl-coenzyme A reductase inhibitor pravastatin. Transplantation. 1996 Oct 15;62(7):934-42.

40. M.M. Kinkhabwala; A. Wilkinson; G. Danovitch; J.T. Rosenthal; A. Sandoval, D.K. Imagawa, S.M. Rudich; P. Seu; R.W. Busuttil. 1996. The Role of Whole Organ Pancreas Transplantation in The Treatment of Type I Diabetes. American Surgeon. 171:516.

41. J.A. Goss; C.R. Shackleton; K. Swenson; N.L. Satou; B.J. Nuesse; D. K. Imagawa, M.M. Kinkhabwala; P. Seu; J.S. Markowitz; S.R. Rudich; S.V. McDiarmid; R.W. Busuttil. 1996. Orthotopic Liver Transplantation for Congenital Biliary Atresia. Annals of Surgery. 224: 276

42. P. Seu; C.R. Shackleton; A. Shaked; D.K. Imagawa; K.M. Olthoff; S.R. Rudich; M.M. Kinkhabwala; R.W. Busuttil. 1996. Improved Results of Liver Transplantation in Patients with Portal Vein Thrombosis. Archives of Surgery. 131:840

43. S. Dawson; D.K. Imagawa; C. Johnson; M. Cecka; P.I. Terasaki; C.R. Shackleton; R.W. Busuttil. 1996. UCLA Liver Transplantation Analysis of Immunological Factors Affecting Outcome. Artificial Organs. 20(10):1063-1072

44. D.G. Farmer; A. Shaked; S.V. McDiarmid; K.M. Olthoff; J.M. Millis; D.K. Imagawa; J.O. Colonna; M.E. Robert; K. Lewin; L.I. Goldstein; R.W. Busuttil. 1996. Small Intestine Transplantation at the University of California, Los Angeles. Transplantation Proceedings. 28(5): 2746-2747.

45. O. Jurim; D. Winston; C. Holt; M. Csete; A. Shaked; D.K. Imagawa; K. Olthoff; C. Shackleton; R. Busuttil; P. Martin. 1996. Failure of Ganciclovir Prophylaxis to Prevent Allograft Reinfection Following Orthotopic Liver Transplantation for Chronic Hepatitis B Infection. Liver Transplantation and Surgery. 2(5):370-4.

46. P. Seu; G. Neelankantia; M. Csete; K. Olthoff; S. Rudich; M. Kinkhabwala; D.K. Imagawa; L.I. Goldstein; P. Martin; C.R. Shackleton; A. Shaked; R.W. Busuttil. 1996. Liver Transplantation for Fulminant Hepatic Failure in a Jehovah's Witness. Clinical Transplantation 10:404-7

47. C. Holt; D.J. Winston; B. Kubak; D.K. Imagawa; P. Martin; L. Goldstein; K. Olthoff; J.M. Millis; A. Shaked; C.R. Shackleton; R.W. Busuttil. 1997. Coccidioidomycosis in Liver Transplant Patients. Clinical Infectious Diseases 24:216-21.

48. J.M. Millis; J. Melinek; M. Csete; D.K. Imagawa; K.M. Olthoff; G. Neelankanta; M.Y.C. Braunfeld; M. Sopher; S.M. Chan; J.L. Pregler; H. Yersiz; A.A. Busuttil; C.R. Shackleton; A. Shaked; R.W. Busuttil. 1997. Randomized Controlled Trial To Evaluate Flush And Reperfusion Techniques In Liver Transplantation. Transplantation 63:397-403.

49. J.L. Kakkis; B. Ke; S. Dawson; W. Chai; F. Kaldas; H. Shau; P. Seu; H. Sauri; R. W. Busuttil; D.K. Imagawa. 1997. Pravastatin Increases Survival and Inhibits Natural Killer Cell Enhancement Factor (NKEF) in Liver Transplanted Rats. J. Surg. Res. 69:393-398.

50. J.A. Goss; H. Yersiz; C. Shackleton; P. Seu; C. Smith; J. Markowitz; D. Farmer; R. Ghobrial; J. Markmann; W. Arnout; D.K. Imagawa; S. Colquhoun; M. Fraiman; S. McDiarmid; R.W. Busuttil. 1997. In Situ Splitting of the Cadaveric Liver for Transplantation. Transplantation. 64:871-877.

51. S. Rudich; M. Kinkhabwala; N. Murray; D. See; R.W. Busuttil; D.K. Imagawa. 1998. Successful Treatment of Mycotic Hepatic Artery Pseudoaneurysms with Arterial Reconstruction and Liposomal Amphotericin B. Liver Transplantation and Surgery. 4:91-93

52. K.M. Swenson; B. Ke; T. Wang; J.S. Markowitz; M.A. Maggard; G.S. Spear; D.K. Imagawa; J.A. Goss; R.W. Busuttil; P. Seu. 1998. Fas Ligand Gene Transfer to Renal Allografts in Rats: Effects on Allograft Survival. Transplantation. 65 2:155-60

53. M.A. Maggard; B. Ke; T. Wang; F. Kaldas; P. Seu; R.W. Busuttil; D.K. Imagawa. 1998. Effects of Pravastatin on Chronic Rejection of Rat Cardiac Allografts. Transplantation. 65 2:149-55

54. H.R. Rosen; P. Martin; J. Goss; J. Donovan; J. Melinek; S. Rudich; D.K. Imagawa; M. Kinkhabwala; P. Seu; R.W. Busuttil; C.R. Shackleton. 1998. Significance of Early Aminotransferase Elevation After Liver Transplantation. Transplantation. 65 1:68-72

55. C.V. Smith; D.K. Imagawa; P.G. Stock; S. Arita; S. Une; T. Kawahara; Y. Sakamoto; M. Ochiai; T. Nagai; L. Shevlin; Y. Mullen. 1998. Simultaneous Islet-Liver Transplantation: Preliminary Results from the UC Islet Transplantation Consortium. Transplantation Proceedings. 30(2):295-6

56. T.S. Dulkanchainun; J.A. Goss; D.K. Imagawa; G.D. Shaw; D.M. Anselmo; F. Kaldas; T. Wang; D. Zhao; H. Kato; N.G.B. Murray; J.W. Kupiec-Weglinski; R.W. Busuttil. 1998. The Reduction of Hepatic Ischemia/Reperfusion Injury by P-Selectin Glycoprotein Ligand-1. Annals of Surgery. 227(6):832-840

57. R.M. Ghobrial,; S. Colquhoun; H. Rosen; P. Hollis; S. Ponthieux; A. Pakrasi; D.G. Farmer; J. F. Markmann; J. Markowitz; K. Drazan; H. Yersiz; J. Singer; R. Stribling; W. Arnout; C.D. Holt; J. Goss; D.K. Imagawa; P. Seu; L.I. Goldstein; C.R. Shackleton; P. Martin; R.W. Busuttil. 1998. Retransplantation for Recurrent Hepatitis C Following Tacrolimus or Cyclosporine Immunosuppression. Transplantation Proceedings. 30(4):1470-1

58. J.S. Markowitz; P. Martin; A.J. Conrad; J.E. Markmann; P. Seu; H. Yersiz; J.A. Goss; P. Schmidt; A. Pakrasi, L. Artinian; N.G.B. Murray; D.K. Imagawa; C. Holt; L.I. Goldstein; R. Stribling; R.W. Busuttil. 1998. Prophylaxis Against Hepatitis B Recurrence Following Liver Transplantation Using Combination Lamivudine and Hepatitis B Immune Globulin. Hepatology. 28(2):585-589

59. S.H. Han; M. Kinkhabwala, P. Martin, C. Holt, N. Murray, P. Seu, S. Rudich, D. Hiserodt, D.K. Imagawa, R.W. Busuttil. 1998. Resolution of recurrent hepatitis in two liver transplant recipients treated with famciclovir. American Journal of Gastroenterology. 93(11):2245-7.

60. Maggard, MA; C. Johnson; T. Wang; P. Terasaki; J.W. Kupiec-Weglinski; R.W. Busuttil; D.K. Imagawa. 1999. Inhibition of Transplant Vasculopathy by Pravastatin is Associated with Attenuated Host Allo-Antibody Response. Transplantation Proceedings. (1-2):728-9.

61. C. Theuer; D.K. Imagawa. 1999. Use of Knitted Oxidized Cellulose (Nu-Knit) for the Definitive Packing of Grade III Liver Fracture. Injury. 30(2):137-140.

62. R.M. Ghobrial; D.G. Farmer; A. Baquerizo; S. Colquhoun; H.R. Rosen; H. Yersiz; J.F. Markmann; K.E. Drazan; Holt, D.K. Imagawa; L.I. Goldstein; P. Martin; R.W. Busuttil. 1999. Orthotopic liver transplantation for hepatitis C: outcome of immunosuppression, and causes of retransplantation during an 8 year single center experience. Annals of Surgery. 229(6):824-31.

63. R.M. Kleinman; S.P. Fagan; M.K. Ray; T.E. Adrian; H. Wong; D.K. Imagawa; J. Walsh; F.C. Brunicardi. 1999. Differential Inhibition of Insulin and Islet Amyloid Polypeptide Secretion by Intraislet Somatostatin in the Isolated Perfused Human Pancreas. Pancreas. 19(4):346-52.

64. X. Wei; M-S Si; D.K. Imagawa; P. Ji; B. Tromberg; M. Calahan. 2000. Perillyl Alcohol Inhibits TCR-Mediated [Ca2+]i Signaling, Alters Shape and Motility and Induces Apoptosis in T Lymphocytes. Cellular Immunology. 201:6-13.

65. R.M. Ghobrial; H. Yersiz; D.G. Farmer; F. Amersi; J. Goss; P. Chen; S. Dawson; S. Lerner; N. Nissen; D.K. Imagawa; S. Colquhoun; W. Arnout; S. McDiarmid; R.W. Busuttil. 2000. Predictors of Survival After In Vivo Split Liver Transplantation: Analysis of 110 Consecutive Cases. Annals of Surgery. 232(3):312-23.

66. M. Maggard; L. Meng; B. Ke; R. Allen; L. Devgan; D.K. Imagawa. 2000. Antisense TGF-?2 Immunotherapy for Hepatocellular Carcinoma. Annals of Surgical Oncology. 8(1):32-37.

67. L.C. Bui; S. Takemoto; S. Cao; T. Le, D.K. Imagawa. 2000. Public Survey of Asian Attitudes on Organ Donation. Pharmacotherapy. 20:1270.

68. Y.D Podnos; J.A. Ortiz; S. Cao; D.K. Imagawa. 2001. Treatment of Groin Lymphocele Following Liver Transplantation with Fibrin Glue. Graft. 4(3):202-204.

69. Y.D. Podnos; J.A. Ortiz; S. Cao; E. Stuffmann; D.K. Imagawa. Laparascopic Ultrasound
With Laparoscopic Radiofrequency Ablation in Patients with Hepatocellular Carcinoma: Technique and Technical Considerations. Am Surg. 2001 Dec;67(12):1181-4.

70. Y.D. Podnos; D.V. Gelfand; T.S. Dulkanchainum; S.E. Wilson; S. Cao; P. Ji; J.A. Ortiz; D.K. Imagawa. Is Intraoperative Cholangiography during Laparoscopic Cholecystectomy Cost Effective? Am J Surg. 2001 Dec;182(6):663-9.

71. Y.D. Podnos; B. Cashmore; J.A. Ortiz; S. Cao; D.K. Imagawa. 2001. Failure of the King’s College Hospital Criteria to Predict Patient Outcome: A Case Report of Spontaneous Recovery Following Fulminant Hepatic Failure. Hospital Physician. 37(9):53-56.

72. L. C. Bui ; S. Cao; M. Sheikh; T.D. Nguyen; J.D. Tran; B. Nguyen; D. K. Imagawa. 2001. Prevalence of Hepatitis B and C in the Vietnamese Immigrants in Southern California. VPhJ. 1(2): 55-57.

73. P. Ji; M.-S. Si; Y. Podnos; D.K. Imagawa. 2002. Monoterpene Geraniol Prevents Acute Allograft Rejection. Transplantation Proceedings. 23, 1418-1419.

74. P. Ji; M.-S. Si; Y. Podnos; H. Chow; E. Steward; D.K. Imagawa. 2002. Prevention of Chronic Rejection by Pravastatin in the Rat Kidney Transplant Model. Transplantation. 74(6): 821-7

75. Y.D. Podnos, J. Carlos; K., P. Ji; S. Cao; J. Cook; R. Busuttil; D.K. Imagawa. 2003. Carcinoid Tumor of the Common Bile Duct: Report of Two Cases. Surgery Today. 33: 553-5.

76. M-S, Si; P. Ji; B. Tromberg; M. Lee; J. Kwok; S-C. Ng; D.K. Imagawa. 2003. Farnesyltransferase Inhibition: A Novel Method of Immunomodulation. International Immunopharmacology. 3(4):475-83.

77. Y. Podnos; J. Cooke; G. Ginther; P. Ji; D. Chapman; R. Newman; D.K. Imagawa. 2003. Prothrombin Mutation G20210A as A Cause of Budd-Chiari Syndrome. Hospital Physician. 39(8): 41-44.

78. M.- Si; D.K. Imagawa; P. Ji.; X. Wei; B. Holm; J. Kwok; M. Lee; B. Reitz; D. C. Borie. 2003.
Immunomudulatory Effects of Docetaxel on Human Lymphocytes. Investigational New Drugs.
21: 281-290.

79. R. F. Holcombe; M. Gu; D. K. Imagawa; T. Milovanovic. 2003. Expression of Kit and Platelet-derived growth factor receptors ? and ? in cholangiocarcinoma, and case report of therapy with imatinib mesylate (STI571). Anti-Cancer Drug. 14:651-657.

80. M.S. Si; A.F. Golish; J.A. Ortiz; J. Zaky; D. Finklestein; R.W. Busuttil; D.K. Imagawa.2003 Prevalence of Metastases in Hepatocellular Carcinoma: Risk Factors and Impact on Survival. Am Surg. 2003 Oct;69(10):879-85.

81. D. S. Finley; M.W. Hinojosa; M.Paya; D.K. Imagawa 2004. Hepatic Artery Pseudoaneursym: A Report of Seven Cases and Review of the Literature, Surgery Today- 2005 35:543-547

82. M.D. Liu; M.B. Uaje; M.S. Al-Ghazi; D.Fields; J.Herman; J.V.Kuo; N.Milne; T.H.Nguyen; N.S. Ramsinghani; K. M. Tokita; F.Y. Tsai; D.J.Vajgrt; D.K.Imagawa 2004. Use of Yttrium-90 TheraSphere for the Treatment of Unresectable Hepatocellular Carcinoma, American Surgeon –2004: 947-953

83. M.S. Si; P.Ji; M.Lee; J.Kwok; J.Kusumoto; E.Naasz; S.C. Ng; D.K.Imagawa: 2004. Potent Farnesyltransferase Inhibitor ABT-100 Abrogates Acute Allograft Rejection, Journal of Heart and Lung Transplantation. 2005-Sept; 24 (9): 1403-9

84. D.S. Finley; W.Teng; J. Ridgeway; D.K. Imagawa: 2004. Fatal Variceal Rupture After Sildenafil Use: Report of a Case, Current Surgery, 62:1-55-56

85. J.Root; N. Nguyen; B. Jones; S. McCloud; J. Lee; P. Nguyen; K. Chang; P. Lin; D.K. Imagawa:
Laparoscopic Distal Pancreatic Resection: Am Surg. 2005 Sep;71(9):744-9

86. V. K. Shrivastava; D.K. Imagawa: 2006. Argon Beam Coagulator for Treatment of Hepatic Rupture With Hemolysis, Elevated Liver Enzymes, Low Platelets (HELLP) Syndrome: Obstetrics & Gynecology-2006; 107:525-526

87. C.E.Foster; R.R. Weng; C.V. Smith; D.K. Imagawa: The influence of organ acceptance criteria on long-term graft survival: outcomes of a kidney transplant program. Am J Surg. 2008 Feb;195(2):149-52.

88. S.Chopra; M.L. Wu; D.K. Imagawa; J.Lee; M. Gu: Endoscopic Ultrasound-Guided fine-needle Aspiration of Undifferentiated Carcinoma With Osteoclast Like Giant Cell Tumor of the Pancreas. Diagnostic Cytopathology. 2007-15;35 (9):601-606

89. J. Wiseman; M. Yamamoto; T.D. Nguyen; D.K. Imagawa. Cystic Pancreatic Neoplasm in Pregnancy: A Case Report and Review of Literature. Arch Surg. 2008 Jan;143(1):84-6.- Primary Contributor (Resident Mentor)

90. M. Yamamoto; M.S. Hayashi; B.U. Jones; P. Lin; K.A.Barrera; J. Lee; T.D. Nguyen; N.T. Nguyen; D.K. Imagawa Laparoscopic Distal Pancreatectomy and Splenectomy for Insulinoma. Video Presentation. 2007. Annals of Surgical Oncology – Primary Contributor (Resident Mentor)

91. M. Yamamoto; D.K. Imagawa; M.H. Katz: Multidisciplinary Management of Resectable Adenocarcinoma of the Pancreatic Head. Expert Review of Anticancer Therapy. 2008 Oct;8(10):1611-21.

92. M. Yamamoto; G. Little; D.K. Imagawa: Hepatitis B immunoglobulin in preventing reinfection following liver transplantation. Expert Review of Anticancer Therapy, 2009 Apr;7(3):321-8. Review.

93. M. Yamamoto; M.S. Hayashi; N.T. Nguyen; T.D. Nguyen; S. McCloud; D.K. Imagawa: Use of Seamguard to Prevent Pancreatic Leak Following Distal Pancreatectomy. Archives of Surgery, 2009 Oct; 144(10):894-9

94. M. Yamamoto; D.K. Imagawa: Hepatitis B Immunoglobulin in Preventing Reinfection Following Liver Transplantation. US Gastroenterology & Hepatology Review, 2009;5:21-4

95. J.S. Mellen; V.W. Xia; M. Hashemzadeh; D.K. Imagawa; M. Jamal; J. Hoefs; K.Q. Hu: The Clinical Presentation of Chronic Hepatitis B Virus Infection in Asian Americans: A Single Center Retrospective Study. Journal of Clinical Gastroenterology, 2010 May-Jun;44(5):364-70

96. H.S. Tran Cao; M. Bouvet; S. Kaushal; A. Keleman; E. Romney; G. Kim; J. Fruehauf; D.K. Imagawa; R.M. Hoffman; M.H. Katz: Metronomic gemcitabine in combination with sunitinib inhibits multisite metastasis and increases survival in an orthotopic model of pancreatic cancer. Molecular Cancer Therapeutics, 2010 Jul;9(7):2068-78. Epub 2010 Jul 6.

97. P.Y. Wong; V. Xia; D.K. Imagawa; J. Hoefs; K.Q. Hu: Clinical Presentation of Hepatocellular Carcinoma (HCC) in Asian-Americans Versus Non-Asian-Americans. J Immigrant Minor Health. 2011 Oct;13(5):842-8.

98. E. Burton; D. Chase; M. Yamamoto; J. de Guzman; D.K. Imagawa; M.L. Berman: Surgical management of recurrent ovarian cancer; the advantage of collaborative surgical management and a multidisciplinary approach. Gynecol Oncol, 2011 Jan:120(1):29-32. Epub 2010 Nov 4.

99. M.H. Katz; T.H. Taylor; W.B. Al-Refaie; M.H. Hanna; D.K. Imagawa; H. Anton-Culver; J.A. Zell: Adenosquamous versus adencarcinoma of the pancreas: a population-based outcomes analysis. J Gastrointest Surg. 2011 Jan;15(1):165-74. Epub 2010 Nov 17.

100. S. Lipkin; J. Lee; D.K. Imagawa; S.M. Hewitt; C. Tucker; J.A. Zell; V. Wong; A. Garcia; R. Gonzalez; G.D. Zanna; E. Richmond; L.M. Rodriguez; M. Bigg; F. Schnoll-Sussmans; F. Meyskens: Phase IIA Trial Testing Erlotinib as an Intervention against Intraductal Pancreatic Mucinous Neoplasms. Cancer Prev Res (Phila). 2011 Apr;4(4):512-3.

101. M. Lamb; R Storrs; S. Li; O. Liang; K. Laugenour; R. Dorian; D. Chapman; H. Ichii; D.K. Imagawa; C.E. Foster, J.R. Lakey: Function and viability injury of human islets encapsulated in alginate sheets: in vitro and in vivo culture. Transplant Proc. 2011 Nov;43(9):3265-6.

102. A.M. Keleman; D.K. Imagawa; L. Findeiss; M.H. Hanna; V.H. Tan; M.H. Katz; S.C. Goodwin; J.S. Lane; D. Vajgrt; T. Nguyen; C.W. Smith: Associated vascular injury in patients with bile duct injury during cholecystectomy. Am Surg. 2011 Oct;77(10):1330-3.

103. J. Hong; J. Wang; A.M. Keleman; D.K. Imagawa; K. Xu; W. Wang; E. Liu; W. Niu; J. Wang; Q. Sun; J. Wang; C. Peng; W. Zhao; J. Niu: Endoscopic versus surgical treatment of downstream pancreatic duct stones in chronic pancreatitis. Am Surg. 2011 Nov;77(11):1531-8.

104. R. Martin; D. Geller; J. Espat; D. Kooby; M. Sellars; R. Goldstein; D.K. Imagawa; C. Scoggins: Safety and efficacy of trans arterial chemoembolization with drug-eluting beads in hepatocellular cancer: a systematic review. Hepatogastroenterology. 2012 Jan-Feb;59(113):255-60. doi: 10.5754/he 10240

105. L.I. Wikholm; D.K. Imagawa; Pneumatosis in Post-Whipple Patients. Am Surg. 2012 Oct;78(10):1105-1108(4)

106. K.A. Simo; E. Hanna; D.K. Imagawa; D. Iannitti; "Hemostatic Agents in Hepatobiliary and Pancreas Surgery: A Review of the Literature and Critical Evaluation of a Novel Carrier-Bound Fibrin Sealant (TachoSil)," ISRN Surgery, vol. 2012, Article ID 729086, 12 pages, 2012. doi:10.5402/2012/729086.

107. W.J. Halabi; C.Y. Kang; N. Ketana; K.J. Lafaro; V.Q. Nguyen; M.J. Stamos; D.K. Imagawa; A.N. Demirjian: Surgery for Gallstone Ileus: A Nationwide Comparison of Trends and Outcomes. Ann Surg. 2014 Feb;259(2):329-35

108. A. Yang MD; C. Lall; P. Bhargava MD; D.K. Imagawa: Limited utility of plain abdominal radiographs in evaluating intussusceptions secondary to long indwelling feeding tubes. J Clin Imaging Sci 2013, 3:9 (28 February 2013)

109. K.J. Lafaro; P. Roumanis; A.N. Demirjian; C. Lall; D.K. Imagawa;: "Gd-EOB-DTPA-Enhanced MRI for Detection of Liver Metastases from Colorectal Cancer: A Surgeon’s Perspective!," International Journal of Hepatology, vol. 2013, Article ID 572307, 7 pages, 2013. doi:10.1155/2013/572307.

110. C.Y. Koh, BA, A.N. Demirjian; W.P. Chen, MS, C.E. McLaren, PhD, D.K. Imagawa: Validation of Revised AJCC Staging for Gallbladder Cancer: A Single Institution Experience. Am Surg. 2005 Sep;71(9):744-9.

111. J.L. Choi, C. Lall, P. Bhargava, D.K. Imagawa: Giant choledochal cyst mimicking massive gallbladder hydrops in an adult patient: multi detector computed tomography and magnetic resonance imaging findings correlated to gross and histopathological findings. J Clin Imaging Sci. 2013 Oct 29;3:45. doi: 10.4103/2156-7514.120785.


Letters, Editorials

1. K.M. Olthoff; M.H. Rosove; C.R. Shackleton; D.K. Imagawa; D.G. Farmer; P. Northcross; A.L. Pakrasi, P. Martin; L.I. Goldstein; A. Shaked; R.W. Busuttil. 1996. Continuous Infusional 5-Fluorouracil Chemotherapy. Annals of Surgery. 224(5):686

2. D.K. Imagawa. 1999. Microsomal Cytochrome P=450 Monooxygenase System and Its Drug-Metabolizing Activity after Partial Portal Vein Ligation in the Rat. World Journal of Surgery. 23:11.

3. M-S. Si; D.K. Imagawa. 2000. Prenylation Inhibitors to Treat Proliferative Renal Disease. Lancet. 355(9213):1460.

4. D.K. Imagawa. 2007. Invited Critique. “The Use of Vascular Clamping in Hepatic Surgery: The
Lessons Learned From 1260 Liver Resections.” Archives of Surgery

5. J. Ortiz; D.K. Imagawa; R. Verzaro; F. Serafini; L.K. Kayler: “Metastatic Lesions to the Liver.” International Journal of Hepatology Volume 2013 (2013), Article ID 104365, 1 page


Book Chapters

B1. D.K. Imagawa; J.M. Cecka. Renal Regrafts. 1988. In: Terasaki, P.I., Ed. Clinical Transplants 1988. UCLA Tissue Typing Laboratory, Los Angeles, California.

B2. J.M. Millis; K.M. Olthoff; D.K. Imagawa; A. Baquerizo; R.W. Busuttil. 1988. Liver Transplantation at UCLA: A Report of Clinical Activities. In: Terasaki, P.I., Ed. Clinical Transplants 1988. UCLA Tissue Typing Laboratory, Los Angeles, California.

B3. D.K. Imagawa; S.M. Strange; A. Shaked; P. Seu; J.O. Colonna; D. Farmer; S.V. McDiarmid; M.P. Morrissey; R.W. Busuttil. 1991. Liver Transplantation at UCLA: Report of Clinical Activities. In: Terasaki, P.I. Ed. Clinical Transplants 1991. UCLA Tissue Typing Laboratory, Los Angeles, California.

B4. D.K. Imagawa; D. Farmer; R.W. Busuttil. 1994. Organ Transplant Rejection. In: Aggarwal B.B., Puri R.K., Eds. Human Cytokines: Their Role in Disease and Therapy. Blackwell Scientific Publication, Boston, Massachusetts

B5. D.K. Imagawa; R.W. Busuttil. 1995. Technical Problems: Vascular. In: Busuttil, R.W.; Klintmalm, G.B., Eds. Transplantation of the Liver. W.B. Saunders Company, Philadelphia, Pennsylvania.

B6. S. Dawson; D.K. Imagawa; J.M. Cecka; P.I. Terasaki; R.W. Busuttil. 1995. UCLA Liver Transplantation: Analysis of the First 1000 Patients. In: Terasaki, P.I.; Cecka, J.M., Eds. Clinical Transplants 1994. UCLA Tissue Typing Laboratory, Los Angeles, California

B7. D.K. Imagawa. 1997. Liver Transplantation. In: Bongard, F; Passaro, E.; Stamos, M.; Eds. Surgery: A Clinical Approach. Churchill Livingstone

B8. M.M. Kinkhabwala; D.K. Imagawa. 1997. Kidney and Pancreas Transplantation. In: Bongard, F.; Passaro, E.; Stamos, M.; Eds. Surgery: A Clinical Approach. Churchill Livingstone.

B9. T.S. Dulkanchainun; D.K. Imagawa. 1998. Liver Transplantation for Complications of Portal Hypertension. In: Sarfeh, I.J.; Ed. Problems in General Surgery: Portal Hypertension. Lippincott-Raven.

B10. D.K. Imagawa. 1998. Novel Therapeutic Approaches in Chronic Rejection. In: Kupiec-Weglinski, J.W.; Ed. Current Opinion in Organ Transplantation: Mechanisms of Rejection. Lippincott Williams & Wilkins.

B11. M.-S. Si; D.K. Imagawa. 2003. Surgical Diseases of the Liver. In: Garland, A; Shatney, C; Sherck, J; and Wren, S., Eds. Surgical Clerkship Manual. Elsevier.

B12. Y. Podnos; D.K. Imagawa. 2003. Transplantation. In: Garland, A; Shatney, C; Sherck, J; and Wren, S., Eds. Surgical Clerkship Manual. Elsevier.

B13. M-S. Si; D.K. Imagawa. Hepatobiliary and Pancreas Surgery. 2003. In: Wilson, S.E.; Ed. Educational Review Manual in General Surgery. Castle Connolly Publishing.

B14. M-S. Si; D.K. Imagawa. Hepatobiliary and Pancreas Surgery.
Educational Review Manual in General Surgery. Castle Connolly Publishing.

B15. M. Yamamoto; D.K. Imagawa. Hepatobiliary and Pancreas Surgery
Educational Review Manual in General Surgery. Castle Connolly Publishing.

B16. D.K. Imagawa; M. Yamamoto. Treatment of Metastatic or Recurrent Colorectal Cancer. Bailey HR, Billingham R, Snyder M, Stamos MJ (Eds) Colon and Rectal Surgery, an Illustrated Manual. Elsevier 2012

B17. J. Lakey, M. Lamb, M. Alexander, D.W. Chapman, D.K. Imagawa, R. Krishnan. Islet Xenotransplantation: An update on recent advances and future prospects. Islets of Langerhans., In Press (2nd ed. 2014)


Abstracts

B.P. Morgan; D.K. Imagawa; J.R. Dankert; L.E. Ramm. Complement Lysis of U937, a Nucleated Mammalian Cell Line, by Complement Proteins C5b-8. 69th Annual Meeting of the Federation of American Societies for Experimental Biology, Anaheim, California, 1985.

B.R.; T.S. Hall; D.K. Imagawa; K. Ueda; W.A. Baumgartner; M. Borkon; R.L. Smith; G.M. Hutchins; B.A. Reitz. Hyperacute Rejection of Cardiac Xenografts: Two New Models Showing Different Pathogenesis. Surgical Forum.

D.K. Imagawa; J. M. Millis; K. M. Olthoff; et al. Elevated Levels of Tumor Necrosis Factor-Alpha Predict Rejection Following Orthotopic Liver Transplantation. Annual Meeting of the Western Association of Transplant Surgeons, Salt Lake City, 1989.

K.M. Olthoff; J.M. Millis; D.K. Imagawa; et al. Comparison of University of Wisconsin solution vs. Euro-Collins solution for cold preservation of liver grafts. 15th Annual Meeting of the American Society of Transplant Surgeons, Chicago, 1989.

D.K. Imagawa; J.M. Millis; K.M. Olthoff; A. Baquerizo; R.W. Busuttil. Anti-tumor Necrosis Factor Antibody Therapy Enhances Cardiac Allograft Survival in Rats. Annual Meeting of the Association for Academic Surgeons, Louisville, 1989.

A. Bacquerizo; N. Kamada; J. Hart; J. M. Millis; C. Pera; K. Olthoff; D. Imagawa; M. Orloff; R.W. Busuttil. Influence of Number and Timing of Serum Transfusions on Liver Allograft Survival in Rats. European Society for Organ Transplantation, Barcelona, Spain, 1989.

K. Teramoto; A. Baquerizo; D.K. Imagawa; K.M. Olthoff; R.A. Dempsey; R.W. Busuttil. Prolongation of Hepatic Allograft Survival in Rat Recipients treated with Anti-Lymphotoxin Antibody. 13th International Congress of the Transplantation Society, San Fransisco, 1990.

P. Seu; D.K. Imagawa; K. M. Olthoff; J.M. Millis; J. Hart; E. Wasef; R.A. Dempsey; R.W. Busuttil. Effects of Tumor Necrosis Factor (TNF) and Immunotherapy Directed Against TNF on Rat Cardiac Transplants. 13th International Congress of the Transplantation Society, San Francisco, 1990.

P. Seu; D.K. Imagawa; K.M. Olthoff; E.M. Wasef; R.A. Dempsey; R.W. Busuttil. Monoclonal Anti-tumor Necrosis Factor-alpha Antibody Treatment of Rat Cardiac Allografts: Synergism with Low-Dose Cyclosporine and Immunohistological Studies. Annual Meeting of the Association for Academic Surgery, Houston, 1990.

K.M. Olthoff; E. Wasef; P. Seu; D.K. Imagawa; I.A. Freischlag; J. Hart; R.W. Busuttil. PGE1 Reduces Injury in Hepatic Allografts Following Preservation. Annual Meeting of the Association for Academic Surgery, Houston, 1990.

M. Shiraishi; A. Shaked; C. Yasunaga; Y. Hasuike; D.K. Imagawa; R.W. Busuttil. Monoclonal Anti-Tumor Necrosis Factor-alpha Antibody Suppresses Rejection, But Enhance Infectious Complications in Rat Liver Allograft Recipients. 14th International Congress of the Transplantation Society, Paris, France, 1992.

F.C. Brunicardi; Y. Oh; L. Shevlin; E. Suh; R. Kleinman; E. Stein; G. Lipaz; D.V. Plant; D.K. Imagawa; H.R. Fetterman; et al. Laser Destruction of Human Nonislet Pancreatic Tissue. Second International Congress of the Cell Transplant Society, Minneapolis, 1994.

M. Millis; D. K. Imagawa; K. Olthoff; P. Martin; A. Gomes; A. Shaked; H. Yersiz; K. Drazen; L. Goldstein; R. Busuttil. TIPS: Impact on Liver Transplantation. 15th World Congress of the Transplantation Society, Kyoto, Japan, 1994.

K.M. Olthoff; M.H. Rosove; D.K. Imagawa; C.R. Shackleton; D. Farmer; P. Martin; L.I. Goldstein; A. Shaked; R.W. Busuttil. Adjuvant Chemotherapy Improves Survival Following Liver Transplantation for Hepatocellular Carcinoma. 106th Annual Session of the Southern Surgical Association, Palm Beach, Fla, 1994.

O. Jurim; C.R. Shackleton; A. Shaked; S.V. McDiarmid; A. Maxfield; J. M. Millis; K. M. Olthoff; D. K. Imagawa; R.W. Busuttil. Living Donor Liver Transplantation at UCLA. 81st Annual Meeting of the North Pacific Surgical Association, Coeur d’Alene, Idaho, 1994.

S. Moldovan; A. Atiya; T.E. Adrian; R.M. Kleinman; K. Lloyd; K. Olthoff; D. Imagawa; L. Shevlin, D. Coy; J. Walsh; F.C. Brunicardi. Somatostatin Inhibits B Cell Secretion Via A Subtype-2 Somatostatin
Receptor in the Isolated Perfused Human Pancreas. Annual Meeting of the Association for Academic Surgery, Albuquerque, New Mexico, 1994.

C.R. Shackleton; P. Martin; J. Melinek; L. Stothers; J.M. Millis; K.M. Olthoff; D.K. Imagawa; M. Kinkhabwala; S. Rudich; P. Seu; A. Shaked; S.V. McDiarmid; L.I. Goldstein; R.W. Busuttil. Lack of
Correlation Between the Magnitude of Preservation Injury and the Incidence of Acute Rejection, Need for OKT3 or Conversion to FK506 in Cyclosporine Treated Primary Liver Allograft Recipients. 45th Annual Meeting of the American Association for the Study of Liver Disease, Chicago, Illinois, 1994

K. Drazan; A. Shaked; K. M. Olthoff; D. K. Imagawa; O. Jurim; K. Kial; C. Schackleton; R. W. Busuttil. Etiology and Management of Symptomatic Adult Hepatic Artery Thrombosis After Orthotopic LiverTransplantation (OLT). Southern California Chapter, American College of Surgeons, Indian Wells, California, 1995.

D.K. Imagawa; K.M. Olthoff; H. Yersiz; C.R. Shackleton; S.D. Colquhoun; A. Shaked; R.W. Busuttil. Rapid En Bloc Technique for Pancreas-Liver Procurement. Improved Early Liver Function. 21st Annual Meeting of the American Society of Transplant Surgeons, Chicago, 1995.

M.M. Kinkhabwala; A. Wilkinson; G. Danovitch; J.T. Rosenthal; A. Sandoval, D.K. Imagawa, S.M. Rudich; P. Seu; R.W. Busuttil. The Role of Whole Organ Pancreas Transplantation in the Treatment of Type I Diabetes. American Surgeon. 82nd Annual Meeting of the North Pacific Surgical Association, Victoria, British Columbia, 1995.

P. Martin; J. Melinik; A.B. Shaked; C. Shackleton; C. Holt; K. Olthoff; D. Imagawa; R.W. Busuttil. 1995. Effect of Donor Hepatitis C Seropositivity on Allograft Infection in Orthotopic Liver Transplantation. Hepatology 22:150A.

D.K. Imagawa; S. Dawson III; C.D. Holt; P. Kirk; F.M. Kaldas; K.M. Olthoff; C.R. Shackleton; A. Shaked; S.V. McDiarmid; P. Seu; S.M. Rudich; M. Kinkhabwala; P. Martin; L.I. Goldstein; S. Saleh; P.I. Terasaki; R.W. Busuttil. 1995. Hyperlipidemia Following Liver Transplantation: Efficacy, Safety, and Immunomodulation with Pravastatin. Hepatology 22:204A.

H.R. Rosen; C.R. Shackleton; P. Martin; J. Donovan; D.K. Imagawa; M. Kinkhabwala; S. Rudich; P. Seu; L.I. Goldstein; R.W. Busuttil. 1995. Impact of Preservation Injury on Long-Term Graft Function, Biliary Complications and Chronic Rejection. Hepatology 22:207A.

D.K. Imagawa; P. Seu; K.M. Olthoff; J.T. Rosenthal; M. Abe; C.R. Shackleton; D. Green; S.M. Rudich; M. Kinkhabwala; R.W. Busuttil. 1995. Maximal Utilization of the "Marginal” Liver Donor: A Prospective Study on the Reliability and Cost Effectiveness of Pre Operative Ultrasound Screening. Hepatology 22:431A.

P. Seu; A. Murano; D.K. Imagawa; P. Kirk; P. Martin; C.R. Shackleton; S.M. Rudich; M. Kinkhabwala; K.M. Olthoff; R.W. Busuttil. 1995. The Use of Hepatitis B Core Antibody Positive Liver Donors. Hepatology 22:489A.

J.L. Kakkis; B. Ke; S. Dawson; W. Chai; F. Kaldas; H. Shau; P. Seu; H. Sauri; R. W. Busuttil; D. K. Imagawa. 1996. Pravastatin Increases Survival and Inhibits Natural Killer Cell Enhancement Factor (NKEF) in Liver Transplanted Rats. Annual Meeting of the Association for Academic Surgery, Chicago, IL, 1996.

C. Holt; J. Goss; S. McDiarmid; P. Martin; P. Nishimura; P. Seu; D. K. Imagawa; R. Stribling; J. Markowitz; R. W. Busuttil. 1996. Efficacy and Safety of Low Dose Tacrolimus and Mycophenolate Mofetil in OLT Recipients. Hepatology Volumae 24, 1996-187.

J.A. Goss; P. Seu; C.V. Smith; J.S. Markowitz; D.G. Farmer; R.M. Ghobrial; J.F. Markmann; S.V. McDiarmid; D.K. Imagawa; S.D. Colquhoun; C.R. Shackleton; M.H. Fraiman; R.W. Busuttil. Expansion of the Donor Pool Utilizing In-Situ Splitting of the Cadaveric Liver. 23rd Annual Scientific Meeting of the American Society of Transplant Surgeons, Chicago, Illinois, 1997.

K. Swenson; P. Seu; B. Ke; T. Wang; F. Kaldas; J. Markowitz; M. Maggard; D.K. Imagawa; A. Jewett; J. Goss; R.W. Busuttil. Fas Ligand Gene Transfer Prolongs Renal Allograft Survival in Rats. 23rd Annual Scientific Meeting of the American Society of Transplant Surgeons, Chicago, Illinois, 1997.

M.A. Maggard; D.K. Imagawa; R.W. Busuttil. Gender Gap Influence on Liver Transplantation Outcome. 23rd Annual Scientific Meeting of the American Society of Transplant Surgeons, Chicago, Illinois, 1997.

T.S. Dulkanchainun; J.A. Goss; D.M. Anselmo; G.D. Shaw; F. Kaldas; T. Wang; N.G.B. Murray; D.K. Imagawa; R.W. Busuttil. The Role of P-Selectin Glycoprotein Ligand-1 (PSGL) in Reduction of Hepatic Ischemia/Reperfusion Injury. 23rd Annual Scientific Meeting of the American Society of Transplant Surgeons, Chicago, Illinois, 1997.

M.A. Maggard; B. Ke; T. Wang; F. Kaldas; P. Seu; R.W. Busuttil; D.K. Imagawa. Pravastatin Protects Against Development of Chronic Rejection in Rat Cardiac Allografts and Upregulates Immunosuppressive TGF-B2. 23rd Annual Scientific Meeting of the American Society of Transplant Surgeons, Chicago, Illinois, 1997.

J. Kakkis; B. Ke; M. Lee; J. Franco; F. Kaldas; R.W. Busuttil; D.K. Imagawa. Analysis of Genetic Modifications in Liver Transplanted Rats Utilizing Messenger RNA Differential Display. 23rd Annual Scientific Meeting of the American Society of Transplant Surgeons, Chicago, Illinois, 1997.

NGB Murray; P. Martin; R. Stribling; J. Goss; A. Pakrasi; P. Hollis; S. Ponthieux; J. Mize; J. Markowitz; D. Farmer; J. Markmann; M. Ghobrial; P. Seu; D.K. Imagawa; R.W. Busuttil. Incidence of De Novo or Recurrent Hepatitis B after Liver Transplantation in the Anti-HB Core Positive Patient. 16th Annual Scientific Meeting of the American Society of Transplant Physicians, Chicago, Illinois, 1997.

T.S. Dulkanchainun; J.A. Goss; D.K. Imagawa; A.A. Busuttil; B.L. Reemtsen; H. Kato; T. Wang; N.G.B. Murray; J.W. Kupiec-Weglinski; R.W. Busuttil. Gadolinium Chloride Induced Blockade Of Kupffer Cells (KC) Ameliorates Ischemia/Reperfussion (I/R) Injury In The Steatotic Liver. 17th Annual Scientific Meeting of the American Society of Transplant Physicians, Chicago, Illinois, 1998.

J. Kakkis; P. Michaels; B. Ke; D. Zhao; H. Kato; S. McDiarmid; D.K. Imagawa; J.W. Kupiec-Weglinski; R.W. Busuttil. Pravastatin-Induced Survival In Rat Orthotopic Liver Transplantation Is Accompanied By Diminished Expression Of 2-Glycoprotein-I And Proinflammatory Cytokines

J.A. Goss; P. Seu; H. Yersiz; D.K. Imagawa; S. Colquhoun; K. Drazan; D.G. Farmer; R.M. Ghobrial; J.F. Markmann; S.V. McDiarmid; R.W. Busuttil. The Effect of In-Situ Split Liver Procurement on Immediate Cadaveric Allograft Function. 24th Annual Scientific Meeting of the American Society of Transplant Surgeons, Chicago, Illinois, 1998.

T.S. Dulkanchainun; J.A. Goss; D.K. Imagawa; A.A. Busuttil; G.D. Shaw; H. Kato; T. Wang; N.G.B. Murray; J.W. Kupiec-Weglinski; R.W. Busuttil. The Reduction of Ischemia/Reperfussion (I/R) Injury by P-Selectin Glycoprotein Ligand-1 (PSGL-1) In A Cold Ischemia Steatotic Liver Model. 24th Annual Scientific Meeting of the American Society of Transplant Surgeons, Chicago, Illinois, 1998.

D.K. Imagawa; M. Si ; M.A. Maggard ; B. Ke ; R.W. Busuttil. p21ras Inhibitors: A New Class of Immunosuppressive Agents? 24th Annual Scientific Meeting of the American Society of Transplant Surgeons, Chicago, Illinois, 1998.

J.A. Goss; C.R. Shackleton; S.V. McDiarmid; B.S. Reemtsen; T.S. Dulkanchainun; P. Seu; D.G. Farmer; R.M. Ghobrial; J.F. Markmann; D.K. Imagawa; R.W. Busuttil. Orthotopic liver Transplantation for Metabolic Liver Disease In The Pediatric Patient. 24th Annual Scientific Meeting of the American Society of Transplant Surgeons, Chicago, Illinois, 1998.

M.A. Maggard; C. Johnson; T. Wang; K. Swenson; J. Kupiec-Weglinski; P. Terasaki; R.W. Busuttil; D.K. Imagawa. Inhibition of Transplant Vasculopathy By Pravastatin Is Associated With Attenuation Of Host Allo-Antibody Responses. 24th Annual Scientific Meeting of the American Society of Transplant Surgeons, Chicago, Illinois, 1998.

M.A. Maggard; D.K. Imagawa; R.W. Busuttil. Comparable Outcomes For ABO Non-Identical and Incompatible Grafts In Liver Transplantation. 24th Annual Scientific Meeting of the American Society of Transplant Surgeons, Chicago, Illinois, 1998.

R.M. Ghobrial; D.G. Farmer; H. Yersiz; J. Goss; F. Amersi; K. Drazan; S. Dawson; P. Chen; L. Romani; D.K. Imagawa; S. Colquhoun; W. Arnaout; S.V. McDiarmid; R.W. Busuttil. Split Liver Transplantation for Expansion of the Donor Pool. 25th Annual Scientific Meeting of the American Society of Transplant Surgeons, Chicago, Illinois. 1999.

H. Yersiz; R.M. Ghobrial; D.G. Farmer; F. Amersi; K. Drazan; P. Chen; S. Dawson; L. Romani; D.K. Imagawa; S. Colquhoun; W. Arnaout; R.W. Busuttil. Expansion of the Donor Pool by Utilization of Cadaveric Livers from Non-Heart Beating Donors. 25th Annual Scientific Meeting of the American Society of Transplant Surgeons, Chicago, Illinois. 1999.

R.M. Ghobrial; D.G. Farmer; C. Holt; H. Rosen; H. Yersiz; K.E. Baquerizo; K. Drazan; P. Chen; S. Dawson; L. Romani; J. Melinek; D.K. Imagawa; P. Seu; L.I. Goldstein; P. Martin; R.W. Busuttil. Tacrolimus versus Cyclosporine Immunosuppression in Liver Transplantation for Hepatitis C. 25th Annual Scientific Meeting of the American Society of Transplant Surgeons, Chicago, Illinois. 1999.

X. Wei; M. Si; D.K. Imagawa; P. Ji; B. Tromberg, M. Calahan. Perillyl Alcohol Inhibits TCR-Mediated [Ca2+]i Signaling, Alters Shape and Motility and Induces Apoptosis in T Lymphocytes. Transplant 2000, First joint Meeting of the American Society of Transplant Surgeons and the American Society of Transplantation, Chicago, Illinois. May 2000.

M.A. Maggard; L. Meng; B. Ke; R. Allen; L. Devgan; D.K. Imagawa. Antisense TGF-?2 Immunotherapy for Hepatocellular Carcinoma. 53rd Meeting of the Society for Surgical Oncology, New Orleans, LA. May 2000.

Y. Podnos; J.A. Ortiz; S. Cao; D.K. Imagawa. Whipple Procedure for Pancreatic Duct Ectasia: Case Report and Review of Literature. 86th Meeting of the American College of Surgeons, Chicago, Illinois. October 2000.

Y. Podnos; D. Serna; D.V. Gelfard; J.A. Ortiz; S. Cao; S. Peck; D.K. Imagawa. Thrombin Glue for the Treatment of Lymphocele and Lymphorrhea. 86th Meeting of the American College of Surgeons, Chicago, Illinois. October 2000.

L.L. Bui; S. Takemoto; S. Cao; T. Le; D.K. Imagawa. Public Survey of Asian Attitudes on Organ Donation. American College of Clinical Pharmacy 2000 Annual Meeting. Los Angeles, CA. November 2000.

Y.D. Podnos; G. Henry; J.A. Ortiz; P. Ji; J. Cooke; S. Cao; E.S. Stuffman, D.K. Imagawa. Laparoscopic Ultrasound with Laparoscopic Radiofrequency Ablation in Patients with Hepatocellular Carcinoma: Technique and Technical Consideration. Annual Scientific Meeting of the Southern California Chapter of the American College of Surgeons, Santa Barbara, California. January 2001.

Y.D. Podnos; J.A. Ortiz; R.M. Fujitani; E.S. Stufmann; S. Cao; D.K. Imagawa. 2001. Orthotopic Liver Transplantation and Simultaneous Aortic Reconstruction. Journal of Investigative Medicine. 49(1): 64A.

E.S. Stuffmann; Y.D. Podnos; J.A. Ortiz; S. Cao; D.K. Imagawa. 2001. Prevalence of Lower Gastrointestional Tract Findings in Liver Transplant Recipients Undergoing Endoscopic and Radiographic Evaluation. Journal of Investigative Medicine. 49(1): 42A.

E.S. Stuffmann; Y.D. Podnos; J.A. Ortiz; S. Cao; D.K. Imagawa. 2001. Subcutaneous Metastasis of Hepatocellular Carcinoma Following CT-Guided Needle Biopsy. Journal of Investigative Medicine. 49(1): 10A.

Y.D. Podnos; C.L. Gray; B. Cashmore; J.A. Ortiz; S. Cao; D.K. Imagawa. 2001. The Failure of Kings Hospital Criteria to Predict Patient Outcome: A Case Report. Journal of Investigative Medicine. 49(1) 9A.

P. Ji; Y.D. Podnos; M.S. Si; E. Steward; D.K. Imagawa. Atorvastatin Prevents Chronic Rejection in Rat Cardiac Allografts. Transplant 2001 Joint Meeting. Chicago, Illinois. May 2001.

P. Ji; Y.D. Podnos; M.S. Si; S. Cao; D.K. Imagawa. Pravastatin Prevents Chronic Allograft Rejection in a Rat Model of Kidney Transplantation. Transplant 2001 Joint Meeting. Chicago, Illinois. May 2001.

P. Ji; Y.D. Podnos; M.S. Si; D.K. Imagawa. Inhibition of p21 Ras Leads to In Vitro and In Vivo Immunosuppression. Transplant 2001 Joint Meeting. Chicago, Illinois. May 2001.

S. Takemoto; L. Bui; S. Cao; T. Le; D.K. Imagawa. Public Survey of Asian Attitudes on Organ Donation. International Conference on Transplantation. Nagoya, Japan. July 2001.

M-S. Si; F. Amersi; R. Golish; J.A. Ortiz; J. Zaky; D. Finklestein; R.W. Busuttil; D.K. Imagawa. Prevalence of Metastases in Hepatocellular Carcinoma: Risk Factors and Impact on Survival. Annual Scientific Meeting of the Southern California Chapter of the American College of Surgeons; Santa Barbara, California. January 2003.

P. Ji; M-S. Si; D.K. Imagawa. Monoterpene Farnesol Prevents Acute Allograft Rejection.
Annual Scientific Meeting of the American Transplant Congress; Washington D.C. June 2003.

M-S. Si; P. Ji; D.K. Imagawa. Farnesyltransferase Inhibition : A Novel Method of Immunomodulation. Annual Scientific Meeting of the American Transplant Congress; Washington D.C. June 2003.

S. Ming; L.C. Bui; B. Reitz; P.Ji; D.K. Imagawa: Effects of Docetaxel on T-Cell Activation: A Role in Immunosuppression. June 2004 American College Clinical Pharmacy

N.Milne, J. Herman, T.H. Nguyen, D. Vajgrt, F.Y. Tsai, M.S. Al-Ghazi, J.V. Kuo, N.S. Ramsinghani, D.K. Imagawa, AJ Cohen, D. Fields, M.D. Liu, K.M. Tokita, M.B. Uaje: The Role of Nuclear Medicine in the Therapy of Hepatoma with Yttrium-90 Mircospheres. The 29th Annual Western Regional Meeting Society of Nuclear Medicine Abstract Form of Scientific Papers and Posters. (Co-Winner of the MD abstract category for the Western Regional SNM meeting) July 2004

J. McEvoy, D.K. Imagawa: Survival After Pancreatic Resection by a Single Surgeon at a University Hospital. Chao Familty Comprehensive Cancer Center Conference, Palm Springs, CA November 2005

J.Root; N.Nguyen; B.Jones; S.McCloud;J.Lee; P. Nguyen; D.K.Imagawa: Laparoscopic Distal Pancreatic Resection. September 2004 Southern California American College of Surgeons.(Scheduled for oral presentation in the General Plenary Session by the Presenter, Jeffrey R. Root, M.D. on January 21, 2005).

D.K. Imagawa: Clinical Presentation and Stage of Hepatocelluar Carcinoma (HCC) in Asian-Americans Versus Non-Asian-Americans. Accepted for presentation at Digestive Disease Week, 2005 in Chicago, IL May 14-15.

M. S. Hayashi; N. Nguyen; D.K. Imagawa; Use of Seam Guard to Prevent Pancreatic Leak Following Distal Pancreatectomy. Accepted for presentation at the SCCS 17th Annual Scientific Meeting, Santa Barbara, CA January 20-22, 2006

D.K. Imagawa; M.S. Hayashi; “Importance of Continued Hepatitis B Immunoglobulin in Preventing Reinfection Following Liver Transplantation”. Accepted for presentation at the Joint International Congress of the International Liver Transplantation Society (ILTS), European Liver and Intestinal Transplant Association (ELITA), and the Liver Intensive Care Group of Europe (LICAGE) Milan, Italy May 5, 2006.

K.Barrera; D.K. Imagawa: Radiofrequency Ablation in the Treatment of Hepatocellular Carcinoma. October 2004- Accepted for Poster Presentation at 2006 UCI Undergraduate Research Symposium, Irvine CA May 13, 2006

D.K. Imagawa; B. Ma; A.P. Venook; M. Bissell; C. Peterson; M. Erion; I Niculae; J. Jensen; D. Bullough; H. Hoyt A Phase I/II Study to Assess the Safety, Tolerability and Pharmacokinetics of Intravenous Infusion of MB07113 in Subjects with Unresectable Hepatocellular Carcinoma (HCC). Accepted for poster presentation at 2007 AACR Annual Meeting, Los Angeles, CA April 16, 2007

M. Yamamoto; A.C. Nguyen; L.C. Nguyen; K. Barrera; T.D. Nguyen; C. Foster; V. H.V. Nguyen; S. Ho; D.K. Imagawa: A Grass-Roots Approach to Increasing Organ Donation In Asians: The Effect of Asian Transplant Awareness In Southern California (ATASC). Accepted for poster presentation at 7th Annual American Society of Transplant Surgeons. Marco Island, FL 2007

M. Yamamoto; D. K. Imagawa; K.A. Barrera; T. D. Nguyen; T. H. Nguyen; D.J. Vajgrt; UC Irvine Medical Center, Orange, CA; Efficacy and Safety of Doxorubicin-Eluting Beads in the Treatment of Hepatocellular Carcinoma. Accepted for poster presentation at Gastrointestinal Cancers Symposium, Orlando, FL 2007

D.K. Imagawa; B. Ma; A.P. Venook; M. Bissell; C. Peterson; M. Erion; I Niculae; J. Jensen; D. Bullough; H. Hoyt: A Phase I/II Study to Assess the Safety, Tolerability and Pharmacokinetics of Intravenous Infusion of MB07113 in Subjects With Unresectable Hepatocellular Carcinoma (HCC).Accepted for poster presentation at 2007 1st International Liver Cancer Association Conference., Barcelona, Spain, October 6, 2007.

E.L. Nelson; D. K. Imagawa; X. Zhao; S. Bhela; J. G. Lee; K. J. Chang; L. B. Wenzel; R. F. Holcombe.. University of California, Irvine, CA: A phase 1 clinical trial of single dose GM-CSF as an immunomodulatory biological adjuvant in clinically-staged, resectable pancreatic adenocarcinoma. AACR Annual Meeting in San Diego, CA 2008

T. H. Nguyen, D. Liu, D.K. Imagawa: Acutely Ruptured Hepatocellular Carcinoma: Should Transarterial Chemoembolization with Doxorubicin Drug-eluting Microspheres be the Initial Treatment of Choice? Presented at the WCIO/ASCO 2008 meeting in Los Angeles, CA 2008

T.H. Nguyen, J. Kuo, M. Katz, D. Imagawa. Beyond Coiling: Use of Vascular Plugs, Onyx, and Hydrogel-coated Coils in Embolization of High Risk Vasculature before Yttrium-90 Radioembolization Treatment. Presented at the WCIO 2010 meeting in Philadelphia, PA 2010

A.M. Keleman, D.K. Imagawa, L. Findeiss, M.H. Hanna, V.H. Tan, M.H. Katz, S.C. Goodwin, J.S. Lane, D. Vajgrt, T. Nguyen, C.W. Smith. Associated vascular injury in patients with bile duct injury during cholecystectomy. Presented at the SCCACS in Santa Barbara, CA, January 2011

J.A. Siegel; D.K. Imagawa; L. Findeiss; J. Landman. Biliary Endoscopy and Lithotripsy of Biliary Stones. Video Presentation at the SAGES 2012 meeting in San Diego, CA 2012

L.Wilkolm, D.K. Imagawa. Pneumatosis in post-Whipple patients. Presented at the SCCACS in Santa Barbara, CA, January 2012

A.N. Demirjian, L. Findeiss, C. Lall, D.K. Imagawa. Use of CT angiography to diagnose associated vascular injuries in patients with common bile duct injuries following cholecystectomy. HPB. 2012;14(Supplement Number 2):117. Presented at the 10th World Congress of the IHPBA in Paris, France 2012

C.Y. Koh, A.N. Demirjian, D.K. Imagawa. Surgical Outcomes of Gallbladder Cancer from a Single Institution. Presented at the SCCACS in Santa Barbara, CA, January 2013.

K.J. Lafaro, G.Tran, D. Fernando, D.J. Vajgrt, L.K. Findeiss, A.N. Demirjian, D.K. Imagawa. Operative management of necrotizing pancreatitis at a single institution. (American Hepato-Pancreato-Biliary Association annual meeting, February 2013).

B. Khalsa, J. Chen, L.K. Findeiss, A.N. Demirjian, D.K. Imagawa. Evolution of the Treatment of Gastroduodenal Artery Pseudoaneurysms and Mesenteric Arterial Hemorrhage Following Pancreaticoduodenectomy. Presented at the DDW (Digestive Disease Week) in Orlando, Florida, May 2013

J. Kim, A.N. Demirjian, D.K. Imagawa. Surgical Management of Pancreatic Neuroendocrine Tumors: a Single Institution Experience. Presented at the DDW (Digestive Disease Week) in Orlando, Florida, May 2013
   
Professional
Societies
American College of Surgeons, Fellow
American Society of Transplant Surgeons
Association of Academic Surgeons
Orange County Surgical Society
Southwestern Surgical Congress
World Artificial Organ, Immunology and Transplantation
   
   
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Last updated 03/04/2014