David K. ImagawaProfessor of Clinical Surgery, Surgery Chief Division of Hepatobiliary and Pancreas Surgery/Islet Cell Transplantation |
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Research Interests |
Liver cancer, pancreatic cancer, bile duct tumor, pathogenesis of chronic rejection, post transplant hyperlipidemia, gene therapy for immunosuppression, reperfusion injury in transplantation, islet cell transplantation | |
| URLs | www.ucihs.uci.edu/com/surgery/index.html | |
| Dr. Imagawa' Profile | ||
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Academic Distinctions | John Connolly Award Winner | |
| Appointments | Chief, Division of Transplantation | |
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Research Abstract |
Research, Clinical Activities, Community Outreach: Liver and pancreatic diseases, bile duct and pancreatic tumor resections, bile duct injuries, biliary reconstruction, minimal invasive treatment of advanced liver tumors, laparascopic, ultrasound guided radiofrequency ablation, biliary reconstruction, pathogenesis of chronic rejection, liver cancer, hepatocellular carcinoma, liver tumor, post transplant hyperlipidemia, clinical trials of novel chemotherapeutic agents, Therasphere, Cirtex, Metabasis, gene therapy for immunosuppression, reperfusion injury in transplantation, islet cell transplantation for complicated Diabetes Mellitus Type I, mechanism of immunomodulation, hepatitis screening, organ donation |
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| Publications | M. Yamamoto; G. Little; D.K. Imagawa: Review of Hepatitis B Immunoglobulin in Preventing Reinfection Following Liver Transplantation – How Much for How Long? Accepted for publication in Expert Review of Anticancer Therapy, In-Press 2008 | |
| M. Yamamoto; D.K. Imagawa; M.H. Katz: Multidisciplinary Management of Resectable Adenocarcinoma of the Pancreatic Head. Expert Review of Anticancer Therapy. 2008 Oct;8(10):1611-21. | ||
| M. Yamamoto; M.S. Hayashi; B.U. Jones; P. Lin; K.A.Barrera; J. Lee; T.D. Nguyen; N.T. Nguyen; D.K. Imagawa Laparoscopic Distal Pancreatectomy and Splenectomy for Insulinoma. Video Presentation. 2007. Annals of Surgical Oncology – Primary Contributor (Resident Mentor) | ||
| J. Wiseman; M. Yamamoto; T.D. Nguyen; D.K. Imagawa. Cystic Pancreatic Neoplasm in Pregnancy: A Case Report and Review of Literature. Accepted for publication in Archive Surgery, In-Press 2007- Primary Contributor (Resident Mentor) | ||
| S.Chopra; M.L. Wu; D.K. Imagawa; J.Lee; M. Gu: Endoscopic Ultrasound-Guided fine-needle Aspiration of Undifferentiated Carcinoma With Osteoclast Like Giant Cell Tumor of the Pancreas. Diagnostic Cytopathology. 2007-15;35 (9):601-606 | ||
| C.E.Foster; D.K. Imagawa; R. Weng; C. Collins; C. Smith: Increased Kidney Acceptance Rate Does Not Adversely Effect Long-Term Graft Survival accepted by the Black Academic Surgeons. Publication in the American Journal of Surgery-Pending | ||
| V. K. Shrivastava; D.K. Imagawa: 2006. Argon Beam Coagulator for Treatment of Hepatic Rupture With Hemolysis, Elevated Liver Enzymes, Low Platelets (HELLP) Syndrome: Obstetrics & Gynecology-2006; 107:525-526 | ||
| J.Root; N. Nguyen; B. Jones; S. McCloud; J. Lee; P. Nguyen; K. Chang; P. Lin; D.K. Imagawa: 2005. Laparoscopic Distal Pancreatic Resection: American Surgeons-2005; 71 (9) 744-9 | ||
| Finley,D; Teng,W; Ridgway,J; Imagawa,D; Fatal Variceal Rupture After Sildenafil Use: Report of a Case. | ||
| Si,M.S;Ji,P;Lee,M;Kwok,J;Kusumoto,J;Naasz,E;Ng,S-C;Imagawa,D;: Potenet Fardesyltransferase Inhibitor ABT-100 Abrogates Acute Allograft Rejection | ||
| Liu,M;Uaje,M;Al-Ghazi,M;Fields,D; Herman,J;Kuo,J;Milne,Nguyen,T;Ramsinghani,N;Tokita,K;Tsai,F;Vajgrt,D; Imagawa,D: Use of Yttrium-90 TheraSphere for the Treatment of Unresectable Hepatocelluar Carcinoma | ||
| Finley,D;Hinojosa,M;Paya,M;Imagawa,D. Hepatic Artery Pseudoaneurym: A Report of Seven Cases and Review of the Literature. | ||
| H.R. Rosen; P. Martin; J. Goss; J. Donovan; J. Melinek; S. Rudich; D.K. Imagawa; M. Kinkhabwala; P. Seu; R.W. Busuttil; C.R. Shackleton. 1998. Significance of Early Aminotransferase Elevation After Liver Transplantation. Transplantation. 65 1:68-72 | ||
| R. F. Holcombe; M. Gu; D. K. Imagawa; T. Milovanovic. 2003. Expression of Kit and Platelet-derived growth factor receptors ? and ? in cholangiocarcinoma, and case report of therapy with imatinib mesylate (STI571). Anti-Cancer Drug. 14:651-657. | ||
| C.V. Smith; D.K. Imagawa; P.G. Stock; S. Arita; S. Une; T. Kawahara; Y. Sakamoto; M. Ochiai; T. Nagai; L. Shevlin; Y. Mullen. 1998. Simultaneous Islet-Liver Transplantation: Preliminary Results from the UC Islet Transplantation Consortium. Transplantation Proceedings. 30(2):295-6 | ||
| T.S. Dulkanchainun; J.A. Goss; D.K. Imagawa; G.D. Shaw; D.M. Anselmo; F. Kaldas; T. Wang; D. Zhao; H. Kato; N.G.B. Murray; J.W. Kupiec-Weglinski; R.W. Busuttil. 1998. The Reduction of Hepatic Ischemia/Reperfusion Injury by P-Selectin Glycoprotein Ligand-1. Annals of Surgery. 227(6):832-840 | ||
| J.S. Markowitz; P. Martin; A.J. Conrad; J.E. Markmann; P. Seu; H. Yersiz; J.A. Goss; P. Schmidt; A. Pakrasi, L. Artinian; N.G.B. Murray; D.K. Imagawa; C. Holt; L.I. Goldstein; R. Stribling; R.W. Busuttil. 1998. Prophylaxis Against Hepatitis B Recurrence Following Liver Transplantation Using Combination Lamivudine and Hepatitis B Immune Globulin. Hepatology. 28(2):585-589 | ||
| S.H. Han; M. Kinkhabwala, P. Martin, C. Holt, N. Murray, P. Seu, S. Rudich, D. Hiserodt, D.K. Imagawa, R.W. Busuttil. 1998. Resolution of recurrent hepatitis in two liver transplant recipients treated with famciclovir. American Journal of Gastroenterology. 93(11):2245-7. | ||
| Maggard, MA; C. Johnson; T. Wang; P. Terasaki; J.W. Kupiec-Weglinski; R.W. Busuttil; D.K. Imagawa. 1999. Inhibition of Transplant Vasculopathy by Pravastatin is Associated with Attenuated Host Allo-Antibody Response. Transplantation Proceedings. (1-2):728-9. | ||
| C. Theuer; D.K. Imagawa. 1999. Use of Knitted Oxidized Cellulose (Nu-Knit) for the Definitive Packing of Grade III Liver Fracture. Injury. 30(2):137-140. | ||
| R.M. Kleinman; S.P. Fagan; M.K. Ray; T.E. Adrian; H. Wong; D.K. Imagawa; J. Walsh; F.C. Brunicardi. 1999. Differential Inhibition of Insulin and Islet Amyloid Polypeptide Secretion by Intraislet Somatostatin in the Isolated Perfused Human Pancreas. Pancreas. 19(4):346-52. | ||
| X. Wei; M-S Si; D.K. Imagawa; P. Ji; B. Tromberg; M. Calahan. 2000. Perillyl Alcohol Inhibits TCR-Mediated [Ca2+]i Signaling, Alters Shape and Motility and Induces Apoptosis in T Lymphocytes. Cellular Immunology. 201:6-13. | ||
| R.M. Kleinman; S.P. Fagan; M.K. Ray; T.E. Adrian; H. Wong; D.K. Imagawa; J. Walsh; F.C. Brunicardi. 1999. Differential Inhibition of Insulin and Islet Amyloid Polypeptide Secretion by Intraislet Somatostatin in the Isolated Perfused Human Pancreas. Pancreas. 19(4):346-52. | ||
| R.M. Ghobrial; H. Yersiz; D.G. Farmer; F. Amersi; J. Goss; P. Chen; S. Dawson; S. Lerner; N. Nissen; D.K. Imagawa; S. Colquhoun; W. Arnout; S. McDiarmid; R.W. Busuttil. 2000. Predictors of Survival After In Vivo Split Liver Transplantation: Analysis of 110 Consecutive Cases. Annals of Surgery. 232(3):312-23. | ||
| M. Maggard; L. Meng; B. Ke; R. Allen; L. Devgan; D.K. Imagawa. 2000. Antisense TGF-?2 Immunotherapy for Hepatocellular Carcinoma. Annals of Surgical Oncology. 8(1):32-37. | ||
| Y.D. Podnos, D.V. Gelfand, T.S. Dulkanchainum; S.E. Wilson, S. Cao, P. Ji; J.A. Ortiz, D.K. Imagawa. 2001. Is Intraoperative Cholangiography during Laparoscopic Cholecystectomy Cost Effective? American Journal of Surgery. 182(6):663-669. | ||
| L. C. Bui ; S. Cao; M. Sheikh; T.D. Nguyen; J.D. Tran; B. Nguyen; D. K. Imagawa. 2001. Prevalence of Hepatitis B and C in the Vietnamese Immigrants in Southern California. VPhJ. 1(2): 55-57. | ||
| M - S. Si; F. Amersi; R. Golis, J.Ortiz; J. Zaky; D. Finklestein; R. Busuttil; D. K. Imagawa. Prevalence of Metastases in Hepatocellular Carcinoma: Risk Factors and Impact on Survival. American Surgeons. 22:51:41. | ||
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M.- Si, D.K. Imagawa; P. Ji.; X. Wei; B. Holm; J. Kwok; M. Lee; B. Reitz; D. C. Borie. 2003. Immunomudulatory Effects of Docetaxel on Human Lymphocytes. Investigational New Drugs. 21: 281-290. |
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| M.- Si, P. Ji; B. Tromberg; M. Lee; J. Kwok; S-C. Ng; D.K. Imagawa. 2003. Farnesyltransferase Inhibition: A Novel Method of Immunomodulation. International Immunopharmacology. 3:475-483. | ||
| P. Ji; M.-S. Si; Y. Podnos; H. Chow; E. Steward; D.K. Imagawa. 2002. Prevention of Chronic Rejection by Pravastatin in the Rat Kidney Transplant Model. Transplantation. 74(6): 821-827 | ||
| P. Ji; M.-S. Si; Y. Podnos; D.K. Imagawa. 2002. Monoterpene Geraniol Prevents Acute Allograft Rejection. Transplantation Proceedings. 23, 1418-1419. | ||
| Podnos YD, Henry G, Ortiz JA, Ji P, Cooke J, Cao S, Imagawa DK. Laparoscopic ultrasound with radiofrequency ablation in cirrhotic patients with hepatocellular carcinoma: technique and technical considerations. Am Surg. 2001 Dec; 67(12):1181-4. | ||
| Ghobrial RM, Yersiz H, Farmer DG, Amersi F, Goss J, Chen P, Dawson S, Lerner S, Nissen N, Imagawa D, Colquhoun S, Arnout W, McDiarmid SV, Busuttil RW. Predictors of survival after In vivo split liver transplantation: analysis of 110 consecutive patients. Ann Surg. 2000 Sep; 232(3):312-23. | ||
| Wei X, Si MS, Imagawa DK, Ji P, Tromberg BJ, Cahalan MD. Perillyl alcohol inhibits TCR-mediated [Ca(2+)](i) signaling, alters cell shape and motility, and induces apoptosis in T lymphocytes. Cell Immunol. 2000 Apr 10; 201(1):6-13. | ||
| Kleinman RM, Fagan SP, Ray MK, Adrian TE, Wong H, Imagawa D, Walsh JH, Brunicardi FC. Differential inhibition of insulin and islet amyloid polypeptide secretion by intraislet somatostatin in the isolated perfused human pancreas. Pancreas. 1999 Nov; 19(4):346-52. | ||
| Ghobrial RM, Farmer DG, Baquerizo A, Colquhoun S, Rosen HR, Yersiz H, Markmann JF, Drazan KE, Holt C, Imagawa D, Goldstein LI, Martin P, Busuttil RW. Orthotopic liver transplantation for hepatitis C: outcome, effect of immunosuppression, and causes of retransplantation during an 8-year single-center experience. Ann Surg. 1999 Jun; 229(6):824-31; discussion 831-3. | ||
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Professional Societies |
American College of Surgeons, Fellow American Society of Transplant Surgeons Association of Academic Surgeons Orange County Surgical Society Southwestern Surgical Congress World Artificial Organ, Immunology and Transplantation |
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| Link to this profile | http://www.faculty.uci.edu/profile.cfm?faculty_id=4828 | |
| Last updated | 07/10/2009 | |