Thomas F. SchillingProfessor, Developmental & Cell Biology |
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Research Interests |
zebrafish, development, neural crest, segmentation, hindbrain, retinoic acid, endothelin, pattern formation, embryogenesis, morphogenesis | |
| URL | http://devcell.bio.uci.edu/tschilling/ | |
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Academic Distinctions | Pew Scholar in Biomedical Sciences | |
| Appointments | University College London and Imperial Cancer Research Fund, London, England | |
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Research Abstract |
development of cell diversity in zebrafish embryos | |
| Publications | White RJ, Nie Q, Lander AD and Schilling TF (2007). Complex regulation of cyp26a1 creates a robust retinoic acid gradient in the zebrafish embryo. PLoS Biol 5(11): e304:doi:10.13711/journal.pbio.0050304. | |
| Bryson-Richardson RJ, Berger S, Schilling TF, Hall TE, Cole NJ, Gibson AJ, Sharpe J and Currie PD (2007). FishNet: an online database of zebrafish anatomy. BMC Biology 5:34 doi:10.1186/1741-7007-5-34. | ||
| Hoffman TF, Javier A, Campeau S, Knight RD and Schilling TF (2007). AP2 transcription factors in zebrafish development and vertebrate evolution. J Exp Zool: Mol Dev Evol 308, 679-691. | ||
| Luo T, Xu Y, Hoffman T, Zhang T, Schilling TF and Sargent TD (2007). Inca: a novel p21-activated kinase-associated protein required for cranial neural crest development. Development, 134, 1279-1289. | ||
| Schilling TF (2007). Genetic regulation of neural and non-neural co-evolution. In "Evolution of Nervous Systems" (ed. J. Kaas) Elsevier. | ||
| Nair S, Wei J, Cornell R and Schilling TF (2007). Requirements for endothelin receptors and endothelin-1 signals from facial ectoderm in patterning skeletogenic neural crest in zebrafish. Development, 134, 335-345. | ||
| Webb J and Schilling TF (2006). Zebrafish in comparative context: a symposium. Journal of Integrative and Comparative Biology 46, 569-576. | ||
| Stafford D, White R, Kinkel MD, Linville A, Schilling TF and Prince V (2006). Retinoids signal directly to zebrafish endoderm to specify insulin-expressing beta-cells. Development 133, 949-956. | ||
| Knight RD and Schilling TF (2006). Skeletogenic lineages of the cranial neural crest. In "Neural Crest Induction and Differentiation" (ed. J.-P. Saint-Jeannet) Landes Bioscience; pp. 120-133. | ||
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Wada N., Javidan Y, Nelson S, Carney TJ, Kelsh RN, and Schilling TF (2005). Hedgehog signaling is required for cranial neural crest morphogenesis and chondrogenesis at the midline in the zebrafish skull. Development 132, 3977-3988. |
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| Holzschuh J, Wada N, Wada C, Schaffer A, Javidan Y, Tallafuss A, Bally-Cuif L, and Schilling TF (2005). Requirements for endoderm and BMP signaling in sensory neurogenesis in zebrafish. Development 132, 3731-3742. | ||
| Plaster N, Sonntag C, Schilling TF and Hammerschmidt M (2007) REREa/Atrophin-2 interacts with histone deacetylase and Fgf8 signaling to regulate multiple processes of zebrafish development. Dev Dyn, 236, 1891-1904. | ||
| Norton WH, Mangoli M, Lele Z, Pogoda H-M, Diamond B, Mercurio S, Russell C, Teraoka H, Stickney HL, Rauch G-J, Heisenberg C-P, Houart C, Schilling TF, Frohnhoefer H-G, Rastegar S, Neumann CJ, Gardiner RM, Strahle U, Geisler R, Rees M, Talbot WS and Wilson SW (2005). Monorail/Foxa2 regulates floorplate differentiation and specification of oligodendrocytes, serotonergic raphe neurons and cranial motoneurones. Development 132, 645-658. | ||
| Knight RD, Javidan Y, Zhang T, Nelson S and Schilling TF (2005). AP2-dependent signals from the ectoderm regulate craniofacial development in the zebrafish embryo. Development 132, 3127-3138. | ||
| Javidan Y and Schilling TF (2004). Development of cartilage and bone. Methods Cell Biol. 76, 415-436. | ||
| Clouthier DE and Schilling TF (2004). Understanding Endothelin-1 function during craniofacial development in the mouse and zebrafish. Birth Defects Res. 72, 190-199. | ||
| Linville A, Gumusaneli E, Chandraratna RA and Schilling TF (2004). Independent roles for retinoic acid in segmentation and neuronal differentiation in the zebrafish hindbrain. Dev. Biol. 270, 186-199. | ||
| Knight RD, Javidan Y, Nelson S, Zhang T and Schilling TF (2004). Skeletal and pigment cell defects in the lockjaw mutant reveal multiple roles for zebrafish tfap2a in neural crest development. Dev. Dyn. 229, 87-98. | ||
| Piotrowski T, Ahn D-G, Schilling TF, Nair S, Ruvinsky I, Geisler R, Rauch G-J, Haffter P, Zon LI, Zhou Y, Foott H, Dawid IB and Ho RK (2003). The zebrafish van gogh mutation disrupts tbx1 which is involved in the DiGeorge deletion syndrome in humans. Development 130, 5043-5052. | ||
| Schilling TF (2003). Evolution and development: making jaws. Heredity 90, 3-5. | ||
| Knight RD, Nair S, Nelson S, Javidan Y, Afshar A, Geisler R, Rauch G-J and Schilling TF (2003). The lockjaw mutation reveals requirements for zebrafish tfap2a in early development of the neural crest. Development 130, 5755-5768. | ||
| Yelick PC and Schilling TF (2002). Molecular dissection of craniofacial development using zebrafish. Crit. Rev. Oral Biol. Med. 13, 308-322. | ||
| David N, Saint-Etienne L, Schilling TF and Rosa F (2002). Critical requirement for endoderm and FGF in ventral head skeleton induction. Development 129, 4457-4468. | ||
| Schilling TF (2002). The morphology of larval and adult zebrafish. In Zebrafish: A Practical Approach. (eds. S. Schulte-Merker and C. Nusslein-Volhard) Oxford Univ. Press, Oxford. | ||
| Schilling TF and Knight RD (2001). Origins of anteroposterior patterning and Hox gene regulation during chordate evolution. Proc. R. Soc. Lond. B 268, 1-15 | ||
| Begemann G, Schilling TF, Rauch JR, Geisler R and Ingham PW (2001) The zebrafish neckless mutation reveals a requirement for raldh2 in mesodermal signals that pattern the hindbrain. Development 128, 3081-3094. | ||
| Schilling TF, Prince V, and Ingham PW (2001). Plasticity in zebrafish hox expression in the hindbrain and cranial neural crest. Developmental Biology 231, 201-216. | ||
| Miller CT, Schilling TF, Lee K, Parker J and Kimmel CB (2000). sucker encodes a zebrafish Endothelin-1 required for ventral pharyngeal arch development. Development 127, 3815-3828. | ||
| Veitch E, Begbie J, Schilling TF, Smith MM and Graham A (2000). Pharyngeal arch patterning in the absence of neural crest. Current Biology 9, 1481-1484. | ||
| Brown L, Rodaway A, Schilling TF, Jowett T, Ingham PW, Patient R and Sharrocks AD (2000). Insights into vasculogenesis revealed by the expression of the ETS-domain transcription factor Fli-1 in wild-type and mutant zebrafish embryos. Mechanisms of Development 90, 237-252. | ||
| Schilling TF, Concordet J-P and Ingham PW (1999). Regulation of left-right asymmetries in the zebrafish by Shh and BMP4. Developmental Biology 210, 277-287. | ||
| Brown L, Amores A, Schilling TF, Jowett T, Baert JL, de Launoit Y and Sharrocks AD (1998). Molecular characterization of the zebrafish PEA3 ETS-domain transcription factor. Oncogene 17, 93-104. | ||
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Professional Societies |
Society for Developmental Biology British Society for Developmental Biology American Association of Anatomists |
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| Graduate Programs |
Developmental Biology and Genetics Cellular and Molecular Biosciences Interdepartmental Neuroscience Program |
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| Research Centers | Developmental Biology Center | |
| Cancer Center | ||
| Link to this profile | http://www.faculty.uci.edu/profile.cfm?faculty_id=4557 | |
| Last updated | 08/22/2008 | |