Richard H LathropAssociate Professor Vice-Chair of Undergraduate Education |
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Research Interests |
Bioinformatics, computational biology, machine learning, artificial intelligence, protein structure prediction, drug discovery, genetic regulation. |
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| URL | www.ics.uci.edu/~rickl/ | |
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Academic Distinctions | AAAI/IAAI Innovative Application, DAC Best Paper, MIT Sprowl, US Patent No. 5,526,281, NSF CAREER and Fellowship, UCI Excellence in Teaching, ICS Outstanding Faculty Teaching and Research, Covers of CACM, JMB, AI Magazine | |
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Research Abstract |
Dr. Lathrop's research for the last 15 years has involved applying intelligent systems and advanced computation to problems in molecular biology. He has broad interests in computational molecular biology, including current research interests in protein structure prediction from sequence, protein-DNA interactions and genetic regulation, rational drug design and discovery, and other molecular structure/function relationships. | |
| Publications | "Combinatorial Optimization in Rapidly Mutating Drug-Resistant Viruses," Lathrop, R.H., Pazzani, M.J., J. Combinatorial Optimization, 3:301-320, 1999. | |
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"An Anytime Local-To-Global Optimization Algorithm for Protein Threading in O(m2n2) Space," Lathrop, R.H. J. Computational Biology, 6(3/4):405-418, 1999. |
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"A Bayes-Optimal Probability Theory that Unifies Protein Sequence-Structure Recognition and Alignment." Lathrop, R.H., Rogers, R.G. Jr., Smith, T.F., White, J.V., Bull. Math. Biol., 60:1039-1071, 1998. |
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"Current Limitations to Protein Threading Approaches," Smith, T.F., Lo Conte, L., Bienkowska, J., Gaitatzes, C., Rogers, R.G. Jr., and Lathrop, R.H., J. Computational Biol., 4(3):217-225, 1997. |
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"Solving the Multiple-Instance Problem with Axis-Parallel Rectangles," Dietterich, T.G., Lathrop, R.H., Lozano-Perez, T., Artificial Intelligence, 89:31-71, 1997. 20(1):13--25, Spring, 1999. |
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Professional Societies |
American Association for Artificial Intelligence
(Life Member) International Society for Computational Biology (member of the founding Board of Directors) |
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| Link to this profile | http://www.faculty.uci.edu/profile.cfm?faculty_id=4556 | |
| Last updated | 02/26/2002 | |