Thomas E. LaneProfessor, Molecular Biology and Biochemistry Director, Biotechnology Master's Program, Molecular Biology and Biochemistry |
|
|
Research Interests |
multiple sclerosis, demyelination, chemokines, inflammation, virology, immunology | |
| URL | darwin.bio.uci.edu/~faculty/lane | |
| Appointments |
Department of Neuropharmacology Scripps Research Institute |
|
|
Research Abstract |
see web site | |
| Publications | Cliffe, L.J., N.E. Humphreys, T.E. Lane, C.S. Potten, C. Booth, and R.K. Grencis (2005). Accelerated intestinal epithelial cell turnover: a new mechanism of parasite expulsion. Science. 308(5727):1463. | |
| Held, K.S., B.P. Chen, W.A. Kuziel, B.J. Rollins, and T.E. Lane (2004). Differential roles of CCL2 and CCR2 in host defense to coronavirus infection. Virology. 329(2):251. | ||
| Trifilo, M.J. and T.E. Lane (2004). The CC chemokine ligand 3 (CCL3) regulates CD11c+CD11b+CD8_- dendritic cell maturation and activation following viral infection of the central nervous system: Implications for a role in T cell activation. Virology. 327(1):8-15. | ||
| Totoiu, M.O., G.I. Nistor, T.E. Lane, and H.S. Keirstead (2004). Remyelination, axonal sparing, and locomotor recovery following transplantation of glial-committed progenitor cells into the MHV model of multiple sclerosis. Exp. Neurol. 187(2):254-265. | ||
| Glass, W.G., M.J. Hickey, J.L. Hardison, M.T. Liu, J.E. Manning, and T.E. Lane (2004). Antibody targeting of the CC chemokine ligand 5 (CCL5) results in diminished leukocyte infiltration into the central nervous system and reduced neurologic disease in a viral model of multiple sclerosis. J. Immunol. 172(7):4018-4025. | ||
| Trifilo, M.J., C. Montalto-Morrison, L.N. Stiles, K.R. Hurst, J.L. Hardison, J.E. Manning, P.S. Masters, and T.E. Lane (2004). The chemokine CXCL10 controls viral infection in the central nervous system: Evidence for a role in innate immune response through recruitment and activation of Natural Killer cells. J. Virol., 78(2):585-594. | ||
| Grants | Principal Investigator: “Chemokines and Viral-Induced Neurologic Disease” R01 NS41249-01A1, 7/05-6/10 NIH- Neurological Disorders and Stroke | |
| Principal Investigator: “Chemokines and Chemokine Receptors and their Roles in Viral-Induced Demyelination” National Multiple Sclerosis Society RG3278, 10/05-9/08 | ||
| “The Chemokine IP-10 and Viral-Induced Demyelination” – submitted as part of a continuing Program Project Grant/NIH titled “Demyelinating Disease: Viral and Immune Function” P01 NS018146, 4/03-3/08 | ||
|
Professional Societies |
American Society of Virology The American Association of Immunologists American Society for Microbiology International Society for Neuroimmunology |
|
| Graduate Programs |
Virology Immunology and Pathogenesis Neurobiology |
|
| Research Centers | Center for Virus Research | |
| Cancer Research Institute | ||
| Reeve-Irvine Research Center | ||
| Center for Immunology | ||
| Link to this profile | http://www.faculty.uci.edu/profile.cfm?faculty_id=4468 | |
| Last updated | 06/29/2009 | |