Professor, Obstetrics & Gynecology
School of Medicine

Gynecologic malignancies, complex pelvic surgeries

www.ucihs.uci.edu/obgyn/amoncbio.htm

Dr. Manetta has always believed in the importance of preventing cervical cancer and detecting it at an early stage. He was awarded a 5 year grant by the NIH National Cancer Institute and is the Principal Investigator of the Single Visit Cervical Cancer Prevention Program. This program is focused on a simplified approach to the screening for cervical cancer.


Dr. Manetta and his colleagues are working on the study of biomarkers in cervical carcinoma and clinical correlation of the novel biomarker MN. Expression of the protein product of the MN gene and of Intestinal alkaline phosphatase is closely correlated with the tumorigenicity of HeLa x fibroblast hybrids. The clinicopathologic correlates of the MN biomarker expression in cervical cancer, the expression of the MN expression in Pap smears associated with clinical regression of dysplasia, and the role of MN in tumorigenesis and the regulation of MN expression have been studied.

Tewari K, Monk BJ, Burger RA, Puthawala A, Vora N, Vasilev SA, Manetta A, Ben-nan ML, Syed AMN, DiSaia PJ. Interstitial brachytherapy in the treatment of advanced and recurrent vulvar cancer. Am J Obstet Gyneco 1, 181:91-8, 1999.

Cloven NG, Manetta A, Berman ML, Kohler MF, DiSaia PJ. Management of ovarian cancer ill patients older than 80 years of age. Gynecol Oncol, 73:137-139, 1999.

Link to this profile
https://faculty.uci.edu/profile/?facultyId=3077

Last updated
01/05/2005