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Nathan D. Wong

Professor, Medicine
School of Medicine

Director, UCI Heart Disease Prevention Program (Preventive Cardiology)
School of Medicine

Professor, Department of, Epidemiology
School of Medicine

Professor, Genetic Epidemiology Research Institute

PH.D., Yale University, 1987

M.P.H., Yale University, 1985

Phone: (949) 824-5561
Fax: (949) 824-5567
Email: ndwong@uci.edu

University of California, Irvine
College of Medicine
C240 Medical Sciences 1
Mail Code: 4079
Irvine, CA 92697

picture of Nathan D. Wong

Epidemiology, prevention, coronary calcium, metabolic syndrome, cardiovascular diseases
URLs Heart Disease Prevention Program
Genetic Epidemiology Research Institute (GERI)
Publications in Pub Med
General Research Interests:

My research has focused on three major areas in cardiovascular epidemiology and prevention:

1) Epidemiology and prognosis of metabolic syndrome

2) Coronary and aortic calcium evaluated by computed tomography and other subclinical measures of atherosclerosis and their epidemiology (including relation to metabolic syndrome) and prognosis

3) Clinical trials aimed at cardiovascular risk factor modification and progression/regression of atherosclerosis

4) Large-scale population-based longitudinal and intervention studies of cardiovascular risk factors in minority youth, women, and older adults: This involves collaborative research with the Coronary Artery Risk Development in Young Adults (CARDIA), Framingham Heart Studies, Multiethnic Study of Atherosclerosis (MESA), Epidemiology of Diabetes Interventions and Complicaitons (EDIC), and other population studies.
Publications Hoang K, Ghandehari H, Lopez VA, Barboza MG, Wong ND. Global coronary heart disease risk assessment of U.S. Persons with the metabolic sydnrome. Diabetes Care 2008; 31: 1405-9.
  119. Detrano R, Guerci AD, Carr JJ, Bild DE, Burke G, Folsom AR, Liu K, Shea S, Szklo M, Bluemke DA, O’Leary DH, Tracy R, Watson K, Wong ND, Kronmal RA. Coronary calcium as a predictor of near-tern coronary heart disease events in major American ethnic groups: the Multiethnic Study of Atherosclerosis (MESA). N Engl J Med 2008; 358: 1336-45.
  117. Wong ND, Lopez VA, L’Italien G, Chen R, Kline S, Franklin SS. High prevalence and treatment rates, but inadequate control of hypertension in U.S. persons in 2003-2004 with cardiovascular disease comorbidities. Arch Intern Med 2007; 167 (22): 2437-42.
  109. Wong ND. Metabolic syndrome: cardiovascular risk assessment and management. Am J Cardiovasc Drugs 2007;7:259-72.
  94. Wong ND, Lopez V, Tang S, Williams GR. Prevalence, treatment and control of combined hypertension and hypercholesterolemia in adults in the USA. Am J Cardiol 2006; 98: 204-208.
  80. Wong ND, Rozanski AR, Gransar H, Dalbeck J, Miranda-Peats R, Hayes S, Shaw L, Friedman J, Polk D, Berman DS. Metabolic syndrome increases the likelihood of inducible myocardial ischemia among patients with subclinical atherosclerosis. Diabetes Care 2005; 28: 1445-50.
  Malik S, Wong ND, Franklin SS, Kamath TV, L’Italien GJ, Pio JR, Williams R. The impact of the metabolic syndrome and diabetes on mortality from coronary heart disease, cardiovascular disease, and all causes in United States adults. Circulation 2004; 110: 1245-1250.
  Wong ND, Kawakubo M, LaBree L, Azen S, Xiang M, Zhuang N, Detrano R. Control of lipids according to National Cholesterol Education Program (NCEP) criteria and coronary calcium progression. Am J Cardiol 2004; 94: 431-436.
  Wong ND, Sciammarella M, Miranda-Peats R, Whitcomb B, Gallagher A, Hachamovich R, Friedman J, Hayes S, Berman DS. The metabolic syndrome, diabetes, and subclinical atherosclerosis assessed by coronary calcium. J Am Coll Cardiol 2003; 41: 1547-53
  Wong ND, Hsu JC, Detrano RC, Diamond G, Eisenberg H, Gardin JM. Coronary artery calcium evaluation by electron beam computed tomography: relation to new cardiovascular events. Am J Cardiol 2000; 86: 495-98.
  46. Franklin SS, Khan SA, Wong ND, Larson MG, Levy D. Is pulse pressure useful in predicting risk for coronary heart disease? The Framingham Heart Study. Circulation 1999; 100: 354-360.
  Wong ND, Detrano RC, Diamond G, Rezayat C, Mahmoudi R, Chong C, Tang W, Puentes G, Kang X, Abrahamson D. Does coronary artery screening by electron beam computed tomography motivate healthy lifestyle behaviors? Am J Cardiol 1996; 78: 1220-3.
  Wong ND, Kowabunpat D, Vo A, Detrano R, Eisenberg H, Goel M, Tobis JM. Coronary calcium in asymptomatic men and women: relation to age and risk factors. Am Heart J 1994; 127: 422-30.
  Wong ND, Wilson PWF, Kannel WB. Serum cholesterol as a risk factor post-myocardial infarction: the Framingham Study. Ann Intern Med 1991: 115: 687-93.
Fellow, American College of Cardiology
Fellow, American Heart Association Council on Epidemiology and Prevention
Graduate Programs Epidemiology

Research Center Genetic Epidemiology Research Institute (GERI)
Link to this profile http://www.faculty.uci.edu/profile.cfm?faculty_id=2414
Last updated 08/31/2012