Kenneth W. Dumars

Professor Emeritus, Pediatrics
School of Medicine

Joint Appointment, Department of Obstetrics & Gynecology and School of Social Ecology


B.S., University of Denver, 1942


M.D., University of Colorado, 1945

Phone: (714) 644-5051
Fax: (714) 644-4164
Email: kwdumars@uci.edu

University of California, Irvine
Department Pediatrics/Genetics, UCI Medical Center
101 The City Drive
Mail Code: 4482
Orange, CA 92868


Research
Interests
Genetics, Cytogenetics, Gene Mapping, Thalassemia, Society,and Ethnic Diversity
   
Academic
Distinctions
Distinguished Service Awards, March of Dimes, Birth Defects Foundation 1976, 1979, and 1989

Invited speaker Fothergill Club, Cardiff Wales

Commendation Award, National Tuberous Sclerosis of America.

Appointments:
Academic appointments prior to UCI: Assistant Clinical Instructor to Assistant Professor at the University of Colorado Medical Center; Assistant Professor of Pediatrics at the University of Kentucky School of Medicine; As a Medical Geneticist, served as consultant to the Colorado State Health Department, to Fort Carson Hospital at Fort Carson, Colorado, and to the Penrose Cancer Hospital in Colorado Springs, Colorado; Visiting Professor, Department of Pediatric Pathology, University Hospital of Wales July 1976- September 1977; Consultant to Department of Genetics, National Research Institute of Mother and Child, Warszawa, Poland 1976-1983.
   
Appointments Academic appointments prior to UCI:
Assistant Clinical Instructor to Assistant Professor at the University of Colorado Medical Center

Assistant Professor of Pediatrics at the University of Kentucky School of Medicine

As a Medical Geneticist, served as consultant to the Colorado State Health Department, to Fort Carson Hospital at Fort Carson, Colorado, and to the Penrose Cancer Hospital in Colorado Springs Colorado

Visiting Professor, Department of Pediatric Pathology, University Hospital of Wales July 1976- September 1977

Consultant to Department of Genetics, National Research Institute of Mother and Child, Warszawa, Poland 1976-1983
   
Research
Abstract
Publications are a partial list of materials published. Throughout a professional career I have been interested in Cultural Diversity and the broad area wherein Genetics impacts Society. Southern California has become even more enriched by the arrival of immigrants from all sectors of the globe; people from the Far East, including Southeast and South Asia, and China, those from the former Soviet Union, people from Africa, and above all those arriving from the countries South of the Border. This cultural diversity challenges all sectors of society to become informed and above all accepting of differences. Diversity includes not only those from differing ethic populations but also diversity created by genetic heterogeneity and medical intervention.

As a subset of those interests I have participated in studies to determine the etiology of chromosomal anomalies and more recently, in collaboration with molecular geneticists, in the identification and molecular composition of gene loci responsible for the production of a number of clinical genetic disorders. P
   
Publications Horner FA, Streamer DW, Clader DE, Hasset MA, Brinkley EL, and Dumars KW. "Effect of Phenylalanine Restricted Diet in Phenylketonuria" AM.J Dis Child 93:615,1957
   
  Dumars KW, Gaskill C, and Kitzmiller N. "Le Cri du Chat (Crying Cat) Syndrome." Amer. J. Dis of Child 108:533-537, 1964
   
  Dumars KW, "Genetic Associate Training Program." J Med Ed 53:768-770, 1978
   
  Dumars, Kenneth W., Timothy Gawron, Catherine L. Pearce, and Carol A. Foster. Prevention of Developmental Disabilities: A Model for Organizing Clinical Activities. Research Developmental Disabilities, 8:507-20, 1987
   
  Baldwin, Clinton, Constantinos D. Constantinou, Kenneth W. Dumars, and Dennis J. Prokop. A single base mutation that converts glycine 907 alpha 2(1) chain of Type I procollegen to aspartate in a lethal variant of Osteogenesis Imperfecta. The single amino acid substitution near the carboxy terminus destabilizes the whole triple helix. J. Biol. Chem. 264:3002-3006, 1989
   
  Dumars, Kenneth W. and Chanthan Chea. "The Cham: A Population Isolate". Thanatology Symposium, The Unwanted Inheritance. Loss, Grief, and Care, Foundation of Thanatology 3/4, 1989
   
  Kandt, Raymond S., Jonathan L. Haines, Moyra Smith, Hope Northrup, R.J.Mckinley Gardner, M.Priscilla Short, K.W. Dumars, et al. Linkage of an Important Gene Locus for Tuberous Sclerosis to Chromosome-16 Marker for Polycystic Kidney Disease. Nature Genetics 2: 37-41, 1992
   
  Sandlin,C.J., B.S.Dodd, K.W.Dumars, et al. Phenotype associated with terminal deletion of the short arm of chromosome 1. American Journal Human Genetics 5 (suppl)701 1995
   
  Dumars, Kenneth W., Corrine Boehm, James R. Eckman, et al. Practical Guide to the Diagnosis of Thalassemia. American Journal of Medical Genetics 62:396-398, 1996
   
  Bedell JA, W.B.Barbazuk, K.M.Wylie, K.W.Dumars, et al., Contig assembly and transcript identification in the 1pdeletion syndrome region. American Journal Human Genetics. 61 suppl:1340 1997
   
  Hathout, Eba H., Kevin Thompson, Marti Blum, Kenneth W. Dumars. Association of Terminal Chromosome 1 Deletion with Sertoli Cell-Only Syndrome. American Journal of Medical Genetics. 80:396-398,1998
   
Professional
Societies
American Society of Human Genetics
Founding Fellow of the College of Medical Genetics
   
Graduate Programs Developmental Biology and Genetics

   
   
Link to this profile http://www.faculty.uci.edu/profile.cfm?faculty_id=2269
   
Last updated 10/14/2009