Kathryn E. OsannAssociate Adjunct Professor, Medicine |
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Research Interests |
Epidemiology, tobacco-related diseases, cancer, cancer prevention, skin cancer, lung cancer, tobacco use prevention, gender differences. | |
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Research Abstract |
Epidemiologic methods, study design, statistical methods, data analysis. | |
| Publications |
PUBLICATIONS (Peer-Reviewed) 1. Stern MP, Haskell WL, Wood P, Osann KE, King AB, Farquhar J. Affluence and cardiovascular risk factors in Mexican Americans and other whites in three Northern California communities. J Chron Dis 1975; 28:623-626. 2. Anton-Culver H, Culver BD, Kurosaki T, Osann KE, Lee JB. Incidence of lung cancer by histologic type from a population-based registry. Cancer Research 1988; 48:6580-6583. 3. Osann KE. Lung cancer in women: the importance of smoking, family history of cancer, and medical history of respiratory disease. Cancer Research 1991; 51:4893-4897. 4. Osann KE, Sweet P, Slater LM. Synergistic interaction of cyclosporin A and verapamil and daunorubicin resistance in multidrug-resistant human leukemia cells in vitro. Cancer Chemother Pharmacol 1992; 30:152-154. 5. Osann KE, Anton-Culver HA, Kurosaki T, Taylor TT. Sex differences in lung cancer risk associated with cigarette smoking. Int J Cancer, 1993; 54:44-48. 6. Brenner M, Kayaley RA, Milne EN, Della Bella L, Osann KE, Tadir Y, Berns MW, Wilson AF. Thoracoscopic laser ablation of pulmonary bullae: Radiographic selection and treatment response. J Thorac Cardiov Surg, 1994; 107:883-890. 7. Barsky SH, Cameron R, Osann KE, Tomita D, Holmes EC. Rising incidence of broncioloalveolar lung carcinoma and its unique clinicopathologic features. Cancer 1994; 73:1163-70. 8. Slater LM, Sweet P, Wetzel M, Stupecky M, Osann K. Comparison of cyclosporin A, verapamil, PSC 833 and cremophor EL as enhancing agents of VP-16 in murine lymphoid leukemias. Leukemia Research, 1995; 19:543-548. 9. Chapman JA, DiSaia PJ, Roth PD, Gilott DL, Osann KE, Berman ML. Estrogen replacement in surgical stage I and II endometrial cancer survivors. American Journal of Obstetrics and Gynecology, 1996; 175(5):1195-200. 10. Slater LM, Sweet P, Stupecky M, Osann K. Superiority of cyclosporin A to PSC-833 in enhancement of VP-16 efficacy in murine tumors in vivo. Cancer Chemotherapy and Pharmacology, 1997; 39:452-454. 11. Brenner M, McKenna R, Gelb A, Osann K, Schein MJ, Panzera J, Wong H, Berns MW, Wilson AF. Objective predictors of response for staple versus laser emphysematous lung reduction. American Journal of Respiratory and Critical Care Medicine, 1997; 155(4):1295-301. 12. Ross HJ, Cho J, Osann KE, Wong SF, Ramsinghani N, Williams J, Downey-Hurtado N, Slater L. Phase I/II trial of low dose cyclosporin A with EP for advanced non-small cell lung cancer. Lung Cancer 1997; 18(2): 189-198. 13. McKenna RJ, Brenner M, Fischel RJ, Singh N, Yoong B, Gelb AF, Osann KE. Patient selection criteria for lung volume reduction surgery. Journal of Thoracic and Cardiovascular Surgery, 1997; 114(6):957-64. 14. Brenner M, McKenna RJ, Gelb AF, Fischel R, Yoong B, Chen J, Huh J, Osann K. Dyspnea response following bilateral thoracoscopic staple lung volume reduction surgery. Chest 1997; 112(4): 916-923. 15. Osann KE. Epidemiology of Lung Cancer. Current Opinion in Pulmonary Medicine, 1998; 4:198-204. 16. Kleinman M, Leaf D, Kelly E, Caiozzo V, Osann K, O'Neill T. Urban angina in the mountains: Effects of carbon monoxide and mild hypoxemia on subjects with chronic stable angina. Archiv Environ H 1998; 53(6):388-397. 17. Brenner M, McKenna RJ Jr, Chen JC, Osann K, Powell L, Gelb AF, Fischel RJ, Wilson AF. Survival following bilateral staple lung volume reduction surgery for emphysema. Chest, 1999; 115(2): 390-396. 18. Serna DL, Brenner M, McKenna RJ, Osann KE, Fischel RJ, Chen JC, Gelb AF, Wildon AF. Survival after unilateral versus bilateral lung volume reduction surgery for emphysema. J Thorac Cardiov Surgery, 1999;118(6):1101-9. 19. Osann KE, Lowery JT, Schell MJ. Small cell lung cancer in women: risk associated with smoking, prior respiratory disease, and occupation. Lung Cancer, 2000; 28(1):1-10. 20. Chuck RS, Behrens A, Wellik SR, Liaw LH, Sweet PM, Osann KE, McDonnell PJ and Berns MW Simple organ culture model for re-epithelialization after in vitro excimer laser ablation. Lasers Surg Med, 2001;29(3):288-92. 21. Nelson LD, Orme D, Osann K, Lott IT. Neurological changes and emotional functioning in adults with Down Syndrome. J Intellect Disabil Res. 2001 Oct;45(Pt 5):450-6. 22. Foss FM, Bacha P, Osann KE, Demierre MF, Bell T, Kuzel T. Biological correlates of acute hypersensitivity events with DAB(389)IL-2 (denileukin diftitox, ONTAK) in cutaneous T-cell lymphoma: decreased frequency and severity with steroid premedication. Clin Lymphoma. 2001 Mar;1(4):298-302. 23. Chuck RS, Behrens A, Wellik S, Liaw LLH, Dolorico, AMT, Sweet PM, Chao LC, Osann, KE, McDonnell PJ and Berns MW Re-epithelialization in cornea organ culture after chemical burns and excimer laser treatment. Arch Ophthalmol, 2001 Nov;119(11):1637-42. 24. Slater LM, Stupecky M, Sweet P, Osann K, Eklof A, Arquilla ER Etoposide induction of tumor immunity in Lewis Lung cancer. Cancer Chemother Pharmacol, 2001 Oct;48(4):327-32. 25. Slater LM, Stupecky M, Sweet P and Osann K Enhancement of leukemia refection by mice successfully treated for L1210 leukemia due to low dose compared to high dose VP-16. Leuk Res, 2002: 26(2):203-206. 26. Brenner M, Gonzalez X, Jones B, Burney T, Ha HP, DeMartino L, Waite-Kennedy T, Osann K, Taylor W, McKenna RJ, Milliken J. Investigation of effects of a novel implantable elastomer device for lung volume reduction surgery in a rabbit model of elastase induced emphysema. Chest, 2002; 121(1): 201-9. 27. Li L, Behrens A, Sweet PM, Osann KE, Chuck RS. Corneal lenticule harvest using a microkeratome and an artificial anterior chamber system at high intrachamber pressure. J Cataract Refract Surg, 2002; 28(5): 860-5. 28. Lott I, Osann K, Doran E, Nelson L. Down syndrome and Alzheimer disease: response to donepezil. Arch Neurol, 2002; 59(7): 1133-6. 29. Erb M, Sioulis C, Kuppermann B, Osann K, Wong C. Differential retinal angiogenic response to sustained intravenous VEGF and bFGF in different pigmented rabbit breeds. Curr Eye Res, 2002; 24(4):245-52. 30. Keefe K, Tadir Y, Tromberg B, Berns M, Osann K, Hashad R, Monk B. Photodynamic therapy of high-grade cervical intraepithelial neoplasia with 5-aminolevulinic acid. Lasers Surg Med, 2002; 31(4):289-293. 31. Chan J, Monk BJ, Cuccia D, Pham H, Kimel S. Gu M, Hammer-Wilson MJ, Liaw LH, Osann K, DiSaia P, Berns M, Tromberg B, Tadir Y. Laparoscopic photodynamic diagnosis of ovarian cancer using 5-aminolevulinic acid in a rat model. Gynecologic Oncology, 2002; 87:64-70. 32. Ebihara A, Krasieva TB, Liaw LH, Fago S, Messadi D, Osann K, Wilder-Smith P. Detection and diagnosis of oral cancer by light-induced fluorescence. Lasers Surg Med. 2003; 32(1):17-24. 33. Charoenbanpachon S, Krasieva T, Ebihara A, Osann K, Wilder-Smith P. Acceleration of ALA-induced PpIX fluorescence development in the oral mucosa.Lasers Surg Med. 2003;32(3):185-8. 34. Chan JK, Loizzi V, Youssef M, Osann K, Rutgers J, Vasilev SA, Berman ML. Significance of comprehensive surgical staging in noninvasive papillary serous carcinoma of the endometrium. Gynecol Oncol. 2003 Jul;90(1):181-5. 35. Chan JK, Loizzi V, Lin YG, Osann K, Brewster WR, DiSaia PJ. Stages III and IV invasive epithelial ovarian carcinoma in younger versus older women: what prognostic factors are important? Obstet Gynecol. 2003 Jul;102(1):156-61. 36. Tungsiripat T, Sarayba M, Taban M, Sweet PM, Osann KE, Chuck RS. Viability of limbal corneal epithelium after anterior lamellar harvesting using a microkeratome. Ophthalmology, 2004; 111:469-75. 37. Chan JK, Monk, B, Brewer, C, Keefe K, Osann K, McMeekin S, Rose GS, Wilczynski S, Meykens F, Berman M. HPV infection and number of lifetime sexual partners are strong predictors for natural regression of CIN II and III. British Journal of Cancer 2003; 89(6):1062-6. 38. Loizzi V, Chan J, Osann K, Capuccini F, DiSaia P, Berman M. Survival outcomes in recurrent ovarian cancer patients treated with chemoresistance assay-guided chemotherapy. Am J Obstet Gyn, 2003; 189(5):1301-7. 39. Szendefi M, Krasieva T, Caduff R, Osann K, Walt H, LaMorte V. Association between promyelocyte protein and small ubiquitin-like modifier protein and the progression of cervical neoplasia. Obstetrics and Gynecology, 2003; 102:1269-77 40. Goldberg, W.A., Osann, K., Filipek, P.A., Laulhere, T., Jarvis, K., Modahl, C., Flodman, P. & Spence, M.A. Language and Other Regression: Assessment and Timing. Journal of Autism and Developmental Disorders, 2003; 33:607-16. 41. Fuja T, Lin F, Osann KE, Bryant PJ. Somatic mutations and latered expression of the candidate tumor suppressors CSNK1?, DLG1 and EDD/hHYD in mammary ductal carcinoma. Cancer Research 2004; 64:942-951. 42. Wilder-Smith P, Osann K, Hanna N, Abbadi N, Brenner M, Messadi D, Krasieva T. In vivo multiphoton fluorescence imaging: a novel approach to oral malignancy. Lasers in Surgery and Medicine, 2004; 35(2):96-103. 43. Wilder-Smith P, Jung WG, Brenner M, Osann K, Beydoun H, Messadi D, Chen Z. In vivo optical coherence tomography for the diagnosis of oral malignancy. Lasers in Surgery and Medicine, 2004; 35(4):269-75. 44. Chan JK, Loizzi V, Magistris A, Lin F, Rutgers J, Osann K, DiSaia PJ, Berman ML. Differences in prognostic molecular markers between women over and under 45 years of age with advanced ovarian cancer. Clinical Cancer Research, 2004; 10:8538-8543. 45. Chan JK, Zhang M, Kaleb V, Loizzi V, Benjamin J, Vasilev S, Osann K, DiSaia PJ. Prognostic factors responsible for survival in sex cord stromal tumors of the ovary- A multivariate analysis. Gynecologic Oncology, 96:204-209, 2005. 46. Wenzel L, Dogan-Ates A, Habbal R, Berkowitz R, Goldstein DP, Bernstein M, M.H.P.,5,7 Kluhsman BC, Osann K, Newlands E, Seckl MJ, Hancock B, Cella D. Defining and Measuring Reproductive Concerns of Female Cancer Survivors. J Natl Cancer Inst Monogr. 2005; 34:94-8. 47. Sarayba MA, Li, L, Tungsiripat T, Liu NH, Sweet PM, Patel AJ, Osann KE, Benson SC, Pershadsingh HA, Chuck RS. Inhibition of corneal neovascularization by a persoisome proliferator-activated receptor-gamma ?ligand. Exp Eye Res. 2005; 80:435-42. 48. Goldberg WA, Jarvis KL, Osann KE, Laulhere TM, Straub C, Thomas E, Filipek P, Spence MA. Early social communication behaviors in the younger siblings of children with autism. J Austism Dev Disorders, in Press 2005. 49. Wilder-Smith P, Krasieva T, Jung WG, Zhang J, Chen Z, Osann K, Tromberg B. Non-invasive imaging of oral premalignancy and malignancy. Accepted for publication in J Biomed Optics 03/05. 50. Hamilton CA, Liou WS, Osann K, Berman ML, Husain A, Teng NN, Kapp DS, Chan JK. The impact of adjuvant therapy on the survival of patients with early-stage uterine papillary serous carcinoma. Accepted for publication in International Journal of Radiation Oncology, Biology and Physics, 2005. 51. Mishra SI, Osann KE, Luce PH, Hubbell FA. Prevalence and Predictors of smoking behavior among American Samoans. Ethnicity and Disease 2005; 15:305-315. 52. Mishra SI, Osann K, Luce P. For the patient. Helping American Samoans quit smoking. Ethnicity and Disease 2005, 15:351-2. 53. Chan JK, Magistris A, Loizzi V, Lin F, Rutgers J, Osann K, Berman ML, Samoszuk M. Mast cell density, angiogenesis, blood clotting and prognosis in women with advanced ovarian cancer. Accepted for publication in Gynecologic Oncology, 2005. |
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| Research Centers | Chao Comprehensive Cancer Center | |
| UCI Autism Research Project | ||
| Link to this profile | http://www.faculty.uci.edu/profile.cfm?faculty_id=2258 | |
| Last updated | 06/03/2005 | |