Peter J. BryantProfessor, Developmental & Cell Biology Co-Director, First-year Integrated Program in Environmental Science Member, Developmental Biology Center |
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Research Interests |
Asymmetric Division of Neural Stem Cells; Local Biodiversity and Conservation | |
| URLs | Peter J. Bryant | |
| Natural History of Orange County, California | ||
| Biodiversity and Conservation: A Hypertext Book | ||
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Research Abstract |
Project 1). Asymmetric Division of Neural Stem Cells. We are studying the mechanisms of cell division in mammalian neural stem cells, using rat models of Parkinson’s Disease and stroke. We are testing the hypothesis that these cells undergo asymmetric cell division, by immunostaining and confocal microscopy using antibodies against the human homologs of asymmetric cell division determinants identified genetically in Drosophila. Project 2). Local Biodiversity and Conservation. We are documenting and monitoring local wildlife populations, including: *Photo-documentation of local species of invertebrates (mainly insects and spiders), field studies of their distribution, seasonality and abundance, and development of a web site showing the identification, life history, interesting features, and conservation issues concerning each species. *Bobcat population and migration monitoring at Laguna Wilderness *Bird counts at Upper Newport Bay and the San Joaquin Wildlife Sanctuary. *Marine Life Inventory at Upper Newport Bay, and intertidal biodiversity along the coast. |
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| Publications | Guerra-Crespo, M., Gleason, D., Sistos, A., Toosky, T., Solaroglu, I., Zhang, J.H., Bryant, P.J., and Fallon, J.H. (200-). Transforming Growth Factor-alpha Induces Neurogenesis and Behavioral Improvement in a Chronic Stroke Model. In Revision. | |
| Bryant, P.J. (2008). Butterfly Wings. Tracks (Newsletter of Newport Bay Naturalists and Friends). June-August issue, pp 1,4. | ||
| Bryant, P.J. (2008). Engaging the Public on Biodiversity Issues. In: In the Light of Evolution, Volume II. Biodiversity and Extinction. Avise, J.C., S.P. Hubbell, and F.J. Ayala (eds.). The National Academies Press, Washington, D.C., pp 311- 321. | ||
| Bryant, P. and Schwartz, P. (2008). Stem Cells. In: Fundamentals of the stem cell debate: The scientific, religious, ethical, and political issues. Berkeley: University of California Press. Monroe, K. R., Miller, R. B., & Tobis, J. S. (Eds.). pp 10-36. | ||
| Schwartz, P. and Bryant, P (2008). Therapeutic Uses of Stem Cells. In: Fundamentals of the stem cell debate: The scientific, religious, ethical, and political issues. Berkeley: University of California Press. Monroe, K. R., Miller, R. B., & Tobis, J. S. (Eds.). pp 37-61. | ||
| Gleason, D, Fallon, J.H., Guerra, M., Liu, J-C., and Bryant P.J. (2008). Ependymal stem cells divide asymmetrically and transfer progeny into the subventricular zone when activated by injury. Neuroscience 156, 81-8. Epub 2008 Jul 11. | ||
| You, X.J., Bryant, P.J., Jurnak, F. and Holcombe, R.F. (2007). Expression of Wnt pathway components frizzled and disheveled in colon cancer arising in patients with inflammatory bowel disease. Oncology Reports 18, 691-4. | ||
| Doleželová, E., Nothacker H.-P., Civelli O., Bryant P.J. and Žurovec M. (2007). A Drosophila adenosine receptor activates cAMP and calcium signaling. Insect Biochem. Molec. Biol. 37, 318-329. | ||
| Terskikh, A., Bryant, P.J. and Schwartz, P.H. (2006). Mammalian stem cells. Pediatric Res. 59, 13R-20R. | ||
| Marble, D. D., Snyder, E. D., Hegle, A. P., Dimitratos, S., Bryant, Peter J. and Wilson, G.F. (2005). Camguk/CASK enhances Ether-a-go-go potassium current by a phosphorylation-dependent mechanism. J. Neurosci. Res. 25, 4898-907. | ||
| Doleželová, E., Žurovec, M., Dolezal, T., Simek, P. and Bryant, P.J. (2005). The Emerging Role of Adenosine Deaminases in Insects. Insect Biochem. Molec. Biol. 35, 381-9. | ||
| Dolezal, T., Doleželová, E., Žurovec, M. and Bryant, P.J. (2005). A role for adenosine deaminase in Drosophila larval development. PLoS Biol. 3, 1213-1224 (e201). | ||
| Fuja, T., Lin, F., Osann, K., and Bryant, P. J. (2004). Somatic Mutations and Altered Expression of the Candidate Tumor Suppressors CSNK1e, DLG1 and EDD/hHYD in Mammary Ductal Carcinoma. Cancer Research 64, 942-951. | ||
| Fuja, T., Hou, S. and Bryant, P. J. (2004). A Multiplex Microsphere Bead Assay for Comparative RNA Expression Analysis Using Flow Cytometry. J. Biotechnology 108, 193-205. | ||
| Fuja, T., Schwartz, P. H., Darcy, D. and Bryant, P. J. (2004). Asymmetric Localization of LGN but not AGS3 in Dividing Human Neural Progenitor Cells. J. Neurosci. Res. 75, 782-793. | ||
| Dolezal, T., Gazi, M., Zurovec, M. and Bryant, P. J. (2003). Genetic analysis of the ADGF multigene family by homologous recombination and gene conversion in Drosophila. Genetics 165, 653-666. | ||
| Schwartz, P.H., Bryant, P. J.,Fuja, T. J., Su, H., O'Dowd, D. K. and Klassen, H. (2003). Isolation and Characterization of Neural Progenitor Cells from Post-Mortem Human Cortex. J. Neurosci. Res. 74, 838-851. | ||
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Professional Society |
Society for Conservation Biology |
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| Other Experience |
Member, Board of Directors and Chair of the Committee on Restoration, Education and Research Newport Bay Naturalists and Friends 2008 |
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Co-Director Interdisciplinary Minor in Global Sustainability, UCI 1996 |
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Director Interdisciplinary Graduate Program in Molecular Biology, Genetics and Biochemistry, UCI 2003—2006 |
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Director Developmental Biology Center, UCI 1979—2003 |
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| Graduate Programs |
Cellular and Molecular Biosciences Cancer Biology Developmental Biology and Genetics |
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| Research Center | Developmental Biology Center | |
| Link to this profile | http://www.faculty.uci.edu/profile.cfm?faculty_id=2128 | |
| Last updated | 01/24/2009 | |