Karen Todd Lane

Picture of Karen Todd Lane
Clinical Professor, Surgery
School of Medicine
Clinical Professor, Surgery
School of Medicine
B.S., University of California, Los Angeles, 1989, Psychobiology
M.D., University of California, Los Angeles, 1993
Phone: (714) 456-8505
Fax: (949)515-3644
Email: klane@hs.uci.edu
University of California, Irvine
3800 W. Chapman Avenue
Suite 6200
Mail Code: 5376
Orange, CA 92868
Research Interests
outcomes, survivorship, high risk
Academic Distinctions
University Women's Scholarship 1984
Alumni Scholar 1984
Regent's Scholar 1984-1988
Dean's Honor List 3 quarters
Graduated Cum Laude 1989
American Federation for Clinical Research: Med Student Award 6/92
Elected to Alpha Omega Alpha--California Delta Chapter 10/92
Janet P. Glasgow Award 5/93
Hewlett-Packard Top Medical Graduate Award 5/93
Longmire Medal for Outstanding Surgery Student 5/93
Dean's Scholar 5/93
Nominated for the Leah J. Dickstein Award 2/93
UCLA Second Year Resident of the Year 1994-1995
UCLA Wilma Miley Morton Research Award 2000
Haile Debas Excellence in Teaching Award 9/05
Orange County Physician of Excellence 9/2007
NAWBO Remarkable Women Award 10/2007
University of California, Irvine Associate’s Grant 10/2007
Orange County Physician of Excellence 2008
UC Irvine Stewardship Star 2010
UC Irvine Hero in Healthcare 7/2011
National Cancer Institute Clinician Award 2011
Top Oncologist by International Association of Oncologists 5/2012
Southern California Super Doctors 2012
National Cancer Institute Clinician Award 2012
Castle Connolly Top Doctors: Southern California 2012
Orange County Physician of Excellence 2012
UC Irvine Hero in Healthcare 7/2012
Patient’s Choice Award 2012
Top 10 Doctors 2012
Southern California Super Doctors 2013
Orange County Physician of Excellence 2013
Southern California Super Doctors 2013
Orange County Physicians of Excellence 2014
Southern California Super Doctors 2014
Orange County Physicians of Excellence 2015
Southern California Super Doctors 2015
Orange County Physicians of Excellence 2016
Southern California Super Doctors 2016
Orange County Physicians of Excellence 2017
Southern California Super Doctors 2017
Orange County Physicians of Excellence 2018
Southern California Super Doctors 2018
Orange County Physicians of Excellence 2019
Southern California Super Doctors 2019
Orange County Physicians of Excellence 2020
Southern California Super Doctors 2020
Orange County Physicians of Excellence 2021
Southern California Super Doctors 2021
Orange County Physicians of Excellence 2022
Southern California Super Doctors 2022
Orange County Physicians of Excellence 2023
Southern California Super Doctors 2023
Publications
Books

1. Garrett A. Wirth MD, Karen T. Lane MD, Keylan Z. Paydar MD. Personalized Breast
Care: A Guide for Cosmetic Surgery, Breast Cancer, and Reconstruction. 2015
Publications

Peer-Reviewed Articles

1. Todd K, Wiley F, Landaw E, Gajewski J, Bellamy P, Harrison R, Brill J, Feig S. Survival outcome among 54 intubated pediatric bone marrow transplant patients. Crit Care Med 1994, 22(1):171-176.

2. Todd K, Kleinman R, Millis M, Brunicardi F.C. The influence of pre-operative donor factors on the performance of the isolated perfused human pancreas. Journal of Surg Res 1994, 56(2):141-145.

3. Todd K, Kleinman R, Brunicardi F.C. Influence of preoperative donor factors on the performance of the isolated perfused human pancreas. Transplantation Proc 1994,26(2):552.

4. Lewis MPN, Kusske AM, Todd K, Toyama MT, Ashley SW, Reber HA. An endothelin ETa/ETb receptor antagonist improves the severity of experimental pancreatitis in rats. Surgical Forum 1996, 47:135-137.

5. Todd KE, Reber HA. The surgical approach to severe acute pancreatitis. Journal of Hep Bil Pancr Surg 1996, 3:241-246.

6. Todd KE, Lewis MPN, Gloor B, Lane JS, Ashley SW, Reber HA. An ETa/ETb endothelin antagonist ameliorates systemic inflammation in a murine model of acute hemorrhagic pancreatitis (AHP). Surgery 1997, 122(2):443-450.

7. Todd KE, Lewis MPN, Gloor B, Kusske AM, Ashley SW, Reber HA. Management decisions for unusual periampullary tumors. Am Surg 1997, 63:927-932.

8. Lane JS, Todd KE, Lewis MPN, Gloor B, Reber HA, McFadden DW, Chandler CF. Interleukin-10 (IL-10) reduces the systemic inflammatory response in a murine model of intestinal ischemia/reperfusion. Surgery 1997, 122:288-294.

9. Gloor B, Todd KE, Reber HA. Surgical therapy for pancreatic pseudocysts. J Gastrointest Surg 1997, 1:203-204.

10. Gloor B, Todd KE, Reber HA. Diagnostic workup of patients with suspected pancreatic carcinoma: the University of California-Los Angeles approach. Cancer 1997, 79(9):1780-1786.

11. Lane JS, Todd KE, Lewis MPN, Gloor B, Ashley SW, Reber HA, McFadden DW, Chandler CF. Interleukin-10 reduces the systemic inflammatory response in a murine model of intestinal ischemia-reperfusion. Surgical Forum 1997, 122(2):288-294.

12. Todd KE, Gloor B, Lane JS, Isacoff WH, Reber HA. Resection of locally advanced pancreatic cancer after downstaging with continuous infusion 5-FU, Mitomycin C, Leucovorin (LV) and Persantine. J Gastrointest Surg 1998, 2(5): 159-166.

13. Lane JS, Kwan DK, Chandler CF, Alexander P, Todd KE, McFadden DW, Ashley SW. Diverting loop versus end ileostomy during ileoanal pull-through procedure for ulcerative colitis. Am Surg 1998, 64(10):979-982.

14. Gloor B, Todd KE, Lane JS, Lewis MPN, Reber HA. Hepatic Kupffer cell blockade reduces mortality in acute hemorrhagic pancreatitis in mice. J Gastrointest Surg 1998, 2(5):430-435.

15. Gloor B, Todd KE, Lane JS, Rigberg DA, Reber HA. Mechanism of increased lung injury after acute pancreatitis in IL-10 knockout mice. J Surg Res 1998, 80(1): 110-114.

16. Lewis MPN, Reber PU, Kusske AM, Toyama MT, Todd KE, Ashley SW, Reber HA. Intragastric alcohol causes endothelin release from feline pancreas. Dig Dis Sci 1998, 43(5):927-930.

17. Lane JS, Todd KE, Rigberg DA, Gloor B, Kau A, Ashley SW, McFadden DW, Reber HA, Chandler CF. Endothelin antagonism reduces the systemic inflammatory response in a murine model of intestinal ischemia-reperfusion. Surgical Forum 1998, 48:119-122.

18. Lewis MP, Lo SK, Reber PU, Patel A, Gloor B, Todd KE, Toyama MT, Sherman S,
Ashley SW, Reber HA. Endoscopic measurement of pancreatic tissue perfusion in patients with chronic pancreatitis and control patients. Gastrointest Endosc 2000, 51(2): 195-199.

19. Gloor B, Blinman TA, Rigberg DA, Todd KE, Lane JS, Hines OJ, Reber HA. Kupffer cell blockade reduces hepatic and systemic cytokine levels and lung injury in hemorrhagic pancreatitis in rats. Pancreas 2000, 21(4): 414-420.

20. Lane JS, Todd KE, Gloor B, Chandler CF, Kau AW, Ashley SW, Reber HA, McFadden DW. Platelet activating factor antagonism reduces the systemic inflammatory response in a murine model of acute pancreatitis. J Surg Res 2001, 99:365-370.

21. Maggard MA, O’Connell JB, Lane KT, Liu JH, Etzioni DA, Ko CY. Do young breast cancer patients have worse outcomes? J Surg Res 2003, 113(1):109-113.

22. Butterfield LH, Ribas A, Meng WS, Dissette VB, Amarnani S, Vu Huong, Seja E, Todd K, Glaspy J, McBride WH, Economou JS. T-Cell responses to HLA-A*0201 immunodominant peptides derived from -Fetoprotein in patients with hepatocellular cancer. Clin Ca Res 2003, 9(16 Pt1):5902-5908.

23. Lang JE, Esserman LJ, Ewing CA, Rugo HS, Lane KT, Leong SP, Hwang S. Accuracy of selective sentinel lymphadenectomy after neoadjuvant chemotherapy: Effect of clinical node status at presentation. J Am Coll Surg 2004, 199:856-862.

24. Lane KT, Esserman LJ. Sentinel Lymph Node Dissection in Early-Stage Breast Cancer: Standards, Controversies and Future Considerations; Oncology Exchange 2004, 3(3):6-13.

25. Maggard, MA, Lane KT, O’Connell JB, Nanyakkara DD, Ko CY. Beyond the clinical trials: How often is sentinel lymph node dissection performed for breast cancer? Ann Surg Oncol 2005, 12(1):41-47.

26. Foster RD, Hansen SL, Esserman LJ, Hwang ES, Ewing C, Lane K, Anthony JP. Safety of immediate transverse rectus abdominis myocutaneous breast reconstruction for patients with locally advanced disease. Arch Surg 2005, 140:196-200.

27. Tan YY, Wu CT, Fan YG, Hwang S, Ewing C, Lane K, Esserman L, Lu Y, Treseler P, Morita E, Leong SP. Primary tumor characteristics predict sentinel lymph node macrometastases in breast cancer. Breast J 2005, 11(5):338-343.

28. Lane JS, Vittinghoff E, Lane KT, Hiramoto JS, Messina LM. Risk factors for premature peripheral vascular disease: Results for the National Health and Nutritional Survey 1999-2002. J Vasc Surg 2006, 44:319-325.

29. Datrice N, Narula N, Butler JA, Hsiang D, Baick C, Lane KT, Do Breast Columnar Cell Lesions with Atypia Need to be Excised? The American Surgeon 2007 Oct;73(10):984-986

30. Hsiang D, Yamamoto M, Mehta R, Baick C, Lane K, Butler J; Predicting nodal status using dynamic contrast-enhanced magnetic resonance imaging in patients with locally advanced breast cancer undergoing neoadjuvant chemotherapy with and without sequential trastuzumab. Archives of Surgery. 2007 Sep;142(9):855-61

31. Yamamoto M, Mehta RS, Baick CH, Su MY, Lane KT, Butler JA, Hsiang DJ. The predictive value of sentinel lymph node biopsy in locally advanced breast cancer patients who have undergone neoadjuvant chemotherapy. Am Surg. 2007 Oct;73(10):977-80.

32. Lane K, Kempf A, Magno C, Lane J, Butler J, Hsiang D, Greenfield S, Jakowatz J, Regional Differences in the Use of Sentinel Lymph Node Biopsy for Melanoma: A Potential Quality Measure. Am Surg. 2008 Oct;74(10):981-4.

33. Lane JS, Magno CP, Lane KT, Chan T, Hoyt DB, Greenfield S. Nutrition impacts the prevalence of peripheral arterial disease in the United States. J Vasc Surg. 2008 Oct;48(4):897-904.

34. Ninh T. Nguyen, Cheryl P. Magno, Karen T. Lane, et. al., Association of Hypertension, Diabetes, Dyslipidemia, and Metabolic Syndrome with Obesity: Findings from the National Health and Nutrition Examination Survey, 1999 to 2004. JACS December 2008; 207(6) 928-934.

35. Chen JH, Bahri S, Mehta RS, Kuzucan A, Yu HJ, Carpenter PM, Feig SA, Lin M, Hsiang DJ, Lane KT, Butler JA, Nalcioglu O, Su MY. Breast Cancer: Evaluation of response to neoadjuvant chemotherapy with 3.0-T MR Imaging. Radiology 2011, 261(3):735-43.

36. Kuzucan A, Chen JH, Bahri S, Mehta RS, Carpenter PM, Hon JY, Hsiang DJ, Lane KT, Butler JA, Feig SA, Su MY. Diagnostic performance of MRI for assessing tumor response in HER2 negative breast cancer receiving neoadjuvant chemotherapy is associated with molecular biomarker profile. Clin Bres Ca 2012, 12(2):110-118..

37. Datrice N, Wirth GA, Hsiang DJ, Butler JA, Lane KT. Can Regional Tattoos Impact Sentinel Lymph Node Identification? Am Surg 2013 79(3):331-332.

38. Hahn EE, Ganz PA, Melisko M, Pierce J, von Friederichs-Fitzwater M, Lane K, Hiatt R for the Athena Breast Health Network. Provider perceptions and expectations of breast cancer post-treatment care: A University of California Athena Breast Health Network project. Journal of Cancer Survivorship 2013, 7(3): 323-330.

39. Chen JH, Bahri S, Mehta RS, Carpenter PM, McLaren CE, Chen WD, Fwu PT, Hsiang DJ, Lane KT, Butler JA, Su MY. Impact of factors affecting the residual tumor size diagnosed by MRI in comparison to pathology. J Clin Oncol 2014, 109 (2):158-167.

40. Schnabel F, Boolbol SK, Gittleman M, Karni T, Tafra L, Feldman S, Police A, Friedman NB, Karlan S, Holmes D, Willey SC, Carmon M, Fernandez K, Akbari S, Harness J, Guerra L, Frazier T, Lane K, Simmons RM, Estabrook A, Allwels T. A randomized prospective study of lumpectomy margin assessment with use of MarginProbe in patients with nonpalpable breast malignancies. Ann Surg Oncol 2014, 21:1589-1595.

41. Masooomi H, Paydar KZ, Evans GRD, Tan E, Lane KT, Wirth GA. Does Immediate Tissue Expander Placement Increase Immediate Postoperative Complications in Breast Cancer Patients? Am Surg. 2015 Feb;81(2):143-9.
Presentations (Grand Rounds, Other)

1. Todd K, Wiley F, Landaw E, Gajewski J, Bellamy P, Harrison R, Brill J, Feig S. Ventilatory support of pediatric BMT patients; Western Medical Research Forum, Carmel, CA; Poster Presentation, February 1992

2. Todd K, Wiley F, Landaw E, Gajewski J, Bellamy P, Harrison R, Brill J, Feig S. Survival outcome among pediatric BMT patients requiring ventilatory support; Int'l Society for Exp. Hematology, Providence, RI; Poster Presentation, July 1992

3. Todd K, Kleinman R, Millis M, Brunicardi F.C. Influence of pre-operative donor factors on the performance of the isolated perfused human pancreas; VA Surgeon's Meeting, Augusta, GA; Oral Presentation, May 1993

4. Todd K, Kleinman R, Millis M, Brunicardi F.C. Influence of pre-operative donor factors on the performance of the isolated perfused human pancreas; ICPIT Meeting, Amsterdam, The Netherlands; Poster Presentation, June 1993

5. Kusske AM, Lewis MPN, Todd K, Toyama MT, Ashley SW, Reber HA. Platelet activating factor (PAF) antagonism markedly reduces pancreas and lung neutrophil accumulation in a caerulein model of acute pancreatitis (AP) in rats; Pancreas Club, San Francisco, CA; Oral Presentation, May 1996

6. Lewis MPN, Kusske AM, Todd KE, Toyama MT, Ashley SW, Reber HA. An endothelin ETa/ETb receptor antagonist improves the severity of experimental pancreatitis in rats; ACS, Surgical Forum, San Francisco, CA; Oral Presentation, October 1996

7. Todd KE, Lane JS, McFadden DW, Ashley SW, Reber HA. Interleukin-10 reduces cytokine levels in a murine model of pancreatitis and sepsis; American Pancreatic Association, Chicago, Illinois; Poster Presentation, November 1996

8. Todd KE, Lewis MPN, Gloor B, Kusske AM, Ashley SW, Reber HA. Management decisions for unusual periampullary tumors; Southern California ACS, Dana Point, CA; Oral Presentation, January 1997

9. Todd KE, Lane JS, McFadden DW, Ashley SW, Reber HA. Interleukin-10 reduces cytokine levels in a murine model of pancreatitis and sepsis; CURE: Digestive Diseases Research Center, Los Angeles, CA; Poster Presentation, February 1997

10. Todd KE, Lewis MPN, Gloor B, Lane JS, Ashley SW, Reber HA. An ETa/ETb Endothelin antagonist ameliorates systemic inflammation in a murine model of acute hemorrhagic pancreatitis (AHP); Society of University Surgeons, Tampa Bay, Florida; Oral Presentation, February 1997

11. Todd KE, Lane JS, Gloor B, Chandler CF, Kwan DK, McFadden DW, Reber HA. Increased severity of acute pancreatitis in IL-10 knockout mice; Pancreas Club, Washington D.C.; Oral Presentation, May 1997

12. Todd KE, Lane JS, Gloor B, Chandler CF, Kwan DK, McFadden DW, Reber HA. Increased severity of acute pancreatitis in IL-10 knockout mice; American Gastroenterological Association, Washington D.C.; Poster Presentation, May 1997

13. Todd KE, Gloor B, Lane JS, Isacoff WH, Reber HA. Resection of locally advanced pancreatic cancer after downstaging with continuous Infusion 5-FU, Mitomycin C, Leucovorin (LV) and Persantine; Society for Surgery of the Alimentary Tract, Washington D.C.; Oral Presentation, May 1997

14. Todd KE, Lewis MPN, Gloor B, Lane JS, Ashley SW, Reber HA. An ETa/ETb Endothelin antagonist ameliorates systemic inflammation in a murine model of acute hemorrhagic pancreatitis (AHP); Surgical Research Tripartite Meeting, Nottingham, England; Oral Presentation, July 1997

15. Todd KE. Breast Cancer Prevention; Little Company of Mary Hospital, Torrance, CA; Lecture, March 2001

16. Todd KE. Breast Cancer and Estrogen Therapy; St. Jude Medical Center, Fullerton, CA; Lecture, September 2001

17. Todd KE. Breast Cancer Update; Marion Medical Center, Santa Maria, CA; Lecture, October 2001

18. Todd KE. Breast Cancer Update; Century City Hospital, Century City, CA; Lecture, February 2002

19. Todd KE. Breast Cancer Assessment, Treatment and Advances; Verdugo Hills Hospital, Glendale, CA; Lecture, May 2002

20. Todd KE. Breast Cancer: the Clinician’s Perspective; UCLA PET CME Program, Los Angeles, CA; Lecture, June 2002

21. Lane KT. Sentinel Lymph Node Dissection in Breast Cancer; UCSF Surgical Grand Rounds, San Francisco, CA; February 2003

22. Lane KT. Selective Sentinel Lymphadenectomy for Breast Cancer; UCSF Lymphatic Mapping/Ultrasound Course, San Francisco, CA; November 2003

23. Lane KT. Local and Regional Therapy for Breast Cancer; UCSF General Surgery Postgraduate
Course, San Francisco, CA; March 2004

24. Lane KT. Local and Regional Therapy for Breast Cancer; UCSF Surgical Grand Rounds, San Francisco, CA; May 2004

25. Lane KT. Selective Sentinel Lymphadenectomy for Breast Cancer; UCSF Lymphatic Mapping/Ultrasound Course, San Francisco, CA; November 2004

26. Lane KT. Breast Cancer Update; UC Irvine Surgical Grand Rounds, Irvine, CA; January 2006

27. Lane KT. Breast Cancer Update. UC Irvine School of Medicine "Breakfast with the Dean" Irvine, CA; March 2, 2006

28. Lane KT. Does the Sentinel Lymph Node Guide Us? UC Irvine Cancer Center Breast Cancer Symposium Irvine, CA; March 6, 2006

29. Lane KT. Breast Surgery. UCI Department of Surgery Intern Lecture, Orange, CA; July 27, 2006

30. Lane KT. Breast Cancer. UCI Department of OB/GYN Resident’s Lecture, Orange, CA; September 15, 2006

31. Lane KT. Clinical Cancer for Basic Scientists: Biology 218 Graduate Course, Irvine, CA; October 12, 2006

32. Lane KT. Breast Cancer Update. A Day of Women’s Health Presented by UCI at the Crystal Cathedral, Orange, CA; October 13, 2006

33. Datrice N, Narula N, Butler JA, Hsiang D, Baick C, Lane KT, Does Breast Columnar Cell Hyperplasia with Atypia Need to be Excised? SCACS Santa Barbara, CA; January 2007

34. Lane KT. Advances in the Diagnosis and Management of Breast Cancer. Kern Medical Center, Bakersfield, CA; January 24, 2007

35. Lane KT. Embracing Cancer Survivorship. Presented by UCI Medical Center Department of Surgery, Orange, CA; February 10, 2007

36. Lane KT. Diagnosis and Management of Breast Cancer. Presented at UCI Cancer Genetics Course, Orange, CA; February 12, 2007

37. Lane KT. Surgical Techniques in the Treatment of Breast Cancer. Kaiser Hospital, Los Angeles, CA; March 13, 2007

38. Lane KT. Breast Cancer Update. Pi Phi Sorority Meeting, Santa Ana, CA; March 15, 2007

39. Lane KT. Symposium on Women’s Cancers. Barclay Theater Irvine, CA; March 27, 2007

40. Lane KT. Basic Science Lecture: Tumor Biology, UCI Medical Center, Orange, CA; March 29, 2007

41. Burke, Lora L, Lane, Karen T., A case of tattoo ink mimicking a blue sentinel lymph node in early stage breast cancer. American Society of Breast Disease, San Francisco, CA; April 12, 2007

42. Lane KT. Lane, JS, Maggard, MA, Invasive ductal breast cancer: Receptor status impacts
degree of node positivity. American Society of Breast Diseases, Phoenix, AZ; May 4, 2007

43. Lane KT. History of Women in Surgery. Anaheim, CA; May 10, 2007

44. Lane KT. Butler, JA, Hsiang D. What’s new in surgical oncology. UC Irvine Medical Center Grand Rounds presentation; Orange, CA, May 24, 2007

45. Lane KT. Breast Cancer Update. Lakewood Regional Med. Center. Lakewood, CA; June 29, 2007

46. Lane KT. Breast Cancer in Post Menopausal Women. Fountain Valley Regional Hospital & Medical Center. Fountain Valley, CA. August 17, 2007

47. Lane KT. Sociocultural Aspects of Breast Cancer: Developing Cultural Competence in Health. St. Jude Medical Center Grand Rounds; Fullerton, CA; September 18, 2007

48. Lane KT. Inflammatory Breast Cancer. Parkview Community Hospital, Riverside, CA October 2, 2007

49. Lane KT. Breast Cancer Update. La Palma Community Hospital Grand Rounds. La Palma, CA; October 22, 2007

50. Lane KT. Update on Breast Cancer Treatment. Garden Grove Hospital Grand Rounds; Garden Grove, CA; October 23, 2007

51. Lane KT. Peptic Ulcer Disease. UCI Medical Center Surgical Grand Rounds Orange, CA; November 1, 2007

52. Lane KT. Breast Cancer Update. Citrus Valley Medical Center: Queen of the Valley; Surgical Grand Rounds; West Covina, CA; November 5, 2007

53. Lane, K, Magno, C, Smith, E, et. al.: University of California, Irvine Cancer Center Meeting; Palm Springs, CA; November 9, 2007

54. Lane KT. Breast Cancer Update. Scripps Mercy Hospital: Medical Grand Rounds; San Diego, CA; December 4, 2007

55. Lane KT. Surgical Grand Rounds: SCACS Lecture, UCI Medical Center, Orange, CA; January 1, 2008

56. Ashley Kempf, BS, Karen Lane, MD, Cheryl Magno, MPH, et. al., Regional Differences in the use of Sentinel Lymph Node Biopsy for Melanoma: A Potential Quality Measure. SCACS Santa Barbara, CA; January 18, 2008

57. Lane KT. Embracing Breast Cancer Survivorship, UCI Medical Center, Orange, CA; February 9, 2008

58. Lane KT. Breast Health. Garden Grove Women’s Chamber of Commerce, Garden Grove, CA. February 21, 2008.

59. Lane KT. Surgical Grand Rounds: DCIS, UCI Medical Center, Orange, CA; March 6, 2008

60. Lane KT. Breast Cancer Survivorship. Komen Breast Health Symposium and Luncheon, Anaheim, CA. March 8, 2008.

61. Lane KT. Breast Cancer Survivorship. National Cancer Survivors Day. Orange, CA; June
5, 2008

62. Lane KT. Surgical Grand Rounds: Benign Breast Disease, UCI Medical Center, Orange, CA; July 24, 2008

63. Lane KT. Surgical Grand Rounds: Breast Cancer Update, Alvarado Hospital, San Diego, CA; September 30, 2008

64. Lane KT. Breast Cancer for the Basic Scientist course MBB218. Irvine, CA; October 16, 2008

65. Lane KT. Breast Cancer Update. P.E.O. Long Beach Chapter; Long Beach, CA; November 5, 2008

66. Lane KT. Women in Surgery event. Lecture to UCI medical students and residents. Irvine, CA; November 20, 2008

67. Lane KT, Datrice N, Nagno C, Smith EC, Butler J, et. al. Evaluating the Quality of Follow-up Care in Breast Cancer Survivors.” Southern California American College of Surgeons; January 17, 2009

68. Lane KT. Breast Cancer Update. Rancho Los Amigos Medical Center; Downey, CA; February 26, 2009

69. Lane KT. Surviving Breast Cancer Survivorship. Beckman Conference Center; Irvine, CA; February 28, 2009

70. Edie Smith, NP; Karen Lane, MD; John Butler, MD; David Hsiang, MD; Expansion of the Nurse Practitioner Role: Genetic Counseling and Testing for Hereditary Breast and Ovarian Cancer. NCBC Conference Las Vegas, NV March 14, 2009

71. Lane KT. Advances in the Diagnosis and Management of Breast Cancer. Lakewood Regional Medical Center; Lakewood, CA April 3, 2009

72. Lane KT. Inflammatory Breast Cancer. UC Irvine Department of Surgery Grand Rounds, Orange, CA April 11, 2009.

73. Lane KT. Evaluation of Nipple Discharge. UC Irvine Department of Surgery Grand Rounds, Orange, CA July 16, 2009.

74. Lane KT. Breast Cancer Update. UC Irvine OB/GYN Resident Lecture, Orange, CA September 18, 2009.

75. Lane KT. Breast Cancer and Pregnancy. UC Irvine Department of Surgery Grand Rounds, Orange, CA October 1, 2009.

76. Lane KT. Breast Cancer Update. Anaheim Regional Medical Center Grand Rounds, Anaheim, CA October 13, 2009.

77. Lane KT. Breast Cancer. UC Irvine Medical Students Lecture, Orange, CA October 14, 2009.

78. Lane KT. Breast Cancer Update. UC Irvine Gynecology Oncology Fellows Lecture, Orange, CA November 13, 2009.

79. Lane KT. Breast Cancer Update. UC Irvine Senior Lecture Series, Newport Beach, CA January 15, 2010.

80. Lane KT. Sociocultural Aspects of Breast Cancer. Torrance Memorial Hospital Grand Rounds, Torrance, CA July 21, 2010.

81. Lane KT. Sociocultural Aspects of Breast Cancer. UC Irvine Department of Surgery Grand Rounds, Orange, CA August 12, 2010.

82. Lane KT. Breast Cancer Update. UC Irvine Family Practice Residents Lecture, Santa Ana, CA March 11, 2010.

83. Lane KT. Breast Cancer: A Chronic Disease. UC Irvine Epidemiology Course, Irvine, CA March 29, 2010.

84. Lane K, Hyunh K, Smith E, Hsiang D, Butler J. Acceptance of chemoprevention by women at high risk for breast cancer. American Society of Breast Surgeons May 2010, Las Vegas, NV

85. Lane KT. Breast Cancer Early Detection and Risk Reduction. ACT Now Lecture, Orange, CA May 15, 2010.

86. Lane KT. Breast Cancer Survivorship. Komen Lecture Series, Orange, CA September 14, 2010.

87. Lane KT. Inflammatory Breast Cancer. UC Irvine OB/GYN Residents Lecture, Orange, CA October 1, 2010.

88. Lane KT. Breast Cancer for Basic Scientists. UC Irvine Molecular Biology 218, Irvine, CA October 7, 2010.

89. Lane KT. Breast Cancer Update. UC Irvine OB/GYN Review Course, Long Beach, CA October 12, 2010.

90. Lane KT. Breast Cancer Survivorship and Pain Management. UC Irvine OB/GYN Grand Rounds, Orange, CA October 15, 2010.

91. Lane KT. Breast Cancer Survivorship. Komen Lecture Series, Costa Mesa, CA November 10, 2010.

92. Lane KT. Surgery as a Career for Women. Brownie Troop #2049, Newport Beach, CA, November 10, 2010.

93. Lane KT. Breast Cancer Update. UC Irvine Occupational Therapy Lecture, Orange, CA December 10, 2010.

94. Piper M, Mehta RS, Butler J, Hsiang D, Wirth G, Lane K. The use of neoadjuvant bevacizumab and postoperative complications in patients undergoing mastectomy with immediate reconstruction. SCACS January 2011, Santa Barbara, CA

95. Lane KT. Breast Cancer and Pregnancy. SCACS, Santa Barbara, CA January 23, 2011

96. Lane KT. Diagnosis and Management of Breast Cancer. UC Irvine Genetics Course, Orange, CA January 26, 2011.

97. Lane KT. Imaging and Risk Assessment for Breast Cancer Patients. St. Judes Hospital Grand Rounds, Fullerton, CA February 15, 2011.

98. Lane KT. Breast Cancer for Basic Scientists. UC Irvine Graduate Biology Course, Irvine, CA February 15, 2011.

99. Lane KT. Breast Cancer Survivorship: UC Irvine Department of Surgery, Anaheim, CA April 30, 2011.

100. Lane KT. Quality of Care for Cancer Survivors. UC Irvine Young Female Cancer Support Group, Irvine, CA May 9, 2011.

101. Lane KT. Breast Cancer Update. Primary Care Review Course. UC Irvine School of Medicine, Orange, CA June 11, 2011.

102. Lane KT. Breast Cancer. OB/GYN Review Course, Long Beach, CA October 25, 2011

103. Datrice N, Lane KT. Can Regional Tattoos Impact Sentinel Lymph Node Identification? UC Irvine Department of Surgery Grand Rounds, January 12, 2012, Orange, CA.

104. Datrice N, Wirth G, Hsiang D, Butler J, Lane KT. Can Regional Tattoos Impact Sentinel Lymph Node Identification? SCACS January 2012, Santa Barbara

105. Lane KT. Breast Cancer Update. UC Irvine Department of OB/GYN Resident Lecture, January 27, 2012.

106. Lane KT. Athena Breast Health Network. UC Irvine Department of Surgery Grand Rounds, Orange, CA April 19, 2012.

107. Lane KT. Women in Surgery. UC Irvine Medical School Women in Surgery Event, Irvine, CA May 9, 2012.

108. Scholz T, Salibian A, Gu M, Lane K, Paydar K, Evans G. Association of osteosarcomas with breast implant capsule: case report and review of literature. CSPS Meeting, San Diego, CA 5/2012.

109. Lane KT. Indications for Axillary Dissection. Pomona Valley Hospital Grand Rounds, July 12, 2012, Pomona, CA

110. Lane KT. Breast Cancer Update. OB/GYN Review Course, Long Beach, CA, October 23, 2012

111. Lane KT. Breast Cancer Awareness. UC Irvine Surgery Interest Group, Irvine, CA,
October 24, 2012.

112. Lane KT. Breast Cancer for Basic Scientists. UC Irvine Bio 218, Irvine, CA, October 25, 2012

113. Lane KT. Neoadjuvant Chemotherapy. Southern California American College of Surgeons Meeting, Breast Section, Santa Barbara, CA, January 19, 2013.

114. Lane KT. What Matters to Me and Why. UC Irvine Chancellors Series. Irvine, CA, February 13, 2013.

115. Lane KT. Biology of Breast Cancer. UC Irvine Undergraduate Biology Course. Irvine, CA February 28, 2013

116. Lane KT. Breast Cancer Update. UC Irvine Gynecology Resident Lecture. Orange, CA, March 1, 2013.

117. Lane KT. Neoadjuvant Chemotherapy for Breast Cancer. UC Irvine Department of Surgery Grand Rounds. Orange, CA, June 20, 2013.

118. Lane KT. Breast Cancer Update. OB/GYN Review Course, Long Beach, CA, October, 2013.

119. Lane KT. Controversies in DCIS. Southern California American College of Surgeons Meeting, Breast Session, Santa Barbara, CA, January, 2014.

120. Masooomi H, Paydar KZ, Evans GRD, Tan E, Lane KT, Wirth GA. Does Immediate Tissue Expander Placement Increase Immediate Postoperative Complications in Breast Cancer Patients? 20. Southern California American College of Surgeons Meeting, Breast Session, Santa Barbara, CA, January, 2014.

121. Lane KT. Biology of Breast Cancer. UC Irvine Undergraduate Biology Course. Irvine, CA, February, 2014.

122. Lane KT. Controversies in DCIS. UC Irvine Department of Surgery Grand Rounds, May 22, 2014, Orange, CA.
Published Abstracts

1. Toyama MT, Kusske AM, Reber PU, Lewis MPN, Todd K, Reber HA, Ashley SW. Administration of a nitric oxide donor decreases the severity of acute pancreatitis. Pancreas 1995, 11(4):451.

2. Todd KE, Lane JS, McFadden DW, Ashley SW, Reber HA. Interleukin-10 Reduces Cytokine Levels in a Murine Model of Pancreatitis and Sepsis. Pancreas 1996, 13(4):458.

3. Kusske AM, Rongione AJ, Lewis MPN, Todd K, Menon S, Xu Y, Ashley SW, McFadden DW, Reber HA. Interleukin-10 (IL-10) reduces the severity of acute hemorrhagic pancreatitis in rats. Gastroenterology 1996, 110(4):A407.

4. Kusske AM, Lewis MPN, Todd K, Toyama MT, Ashley SW, Reber HA. Platelet activating factor (PAF) antagonism markedly reduces pancreas and lung neutrophil accumulation in a caerulein model of acute pancreatitis (AP) in rats. Gastroenterology 1996, 110(4):A1399.

5. Lewis MPN, Kusske AM, Todd K, Toyama MT, Rongione AJ, Ashley SW, Reber HA. Improvement of experimental acute pancreatitis (AP) by an endothelin ETa/ETb receptor antagonist. Gastroenterology 1996, 110(4):A4

6. Toyama MT, Lewis MPN, Kusske AM, Todd K, Ashley SW, Reber HA. The isolated perfused pancreas/liver. A new model for the study of free radical production and systemic manifestations of acute pancreatitis. Gastroenterology 1996, 110(4):A438.

7. Lane JS, Todd KE, McFadden DW, Reber HA, Ashley SW. Interleukin-10 reduces severity early in the course of pancreatitis. Pancreas 1996, 13(4):445.

8. Lewis MPN, Gloor B, Todd KE, Sampogna S, Ashley SW, Reber HA. Human chronic pancreatitis is associated with ductal and vascular endothelial immunostaining for endothelin-1. Pancreas 1996, 13(4):447.

9. Gloor B, Todd KE, Lane JS, Lewis MPN, Reber HA. Kupffer cell activation increases serum cytokines in a model of acute pancreatitis. Gastroenterology 1997, 112:A444.

10. Todd KE, Lane JS, Gloor B, Chandler CF, Kwan DK, McFadden DW, Reber HA. Increased severity of acute pancreatitis in IL-10 knockout mice. Gastroenterology 1997, 112:A487.

11. Gloor B, Todd KE, Lane JS, Lewis MPN, Reber HA. Hepatic Kupffer cell blockade reduces mortality in acute hemorrhagic pancreatitis in mice. Gastroenterology 1997, 112:A1444.

12. Lane JS, Whang EE, Todd KE, Kwan D, Newton T, Diamond J, Zinner MJ, McFadden
DW, Ashley SW. Paracellular pathway plays a minor role in jejunal glucose transport in the unanesthetized dog. Gastroenterology 1997, 112:A378.

13. Lane JS, Schew WA, Todd KE, Chandler CF, Diamond J, Ashley SW. Growth hormone increases mucosal nutrient transport efficiency following intestinal resection. Gastroenterology 1997, 112:A378.

14. Todd KE, Gloor B, Lane JS, Isacoff WH, Reber HA. Resection of locally advanced pancreatic cancer after downstaging with continuous infusion 5-FU, Mitomycin C, Leucovorin (LV) and Persantine. Gastroenterology 1997, 112: A1479.

15. Lane JS, Todd KE, Gloor B, Chandler CF, Kau AD, Ashley SW, Reber HA, McFadden DW. Platelet activating factor (PAF) antagonism reduces the systemic inflammatory response in a murine model of acute pancreatitis. Gastroenterology 1997, 112:A1454.

16. Hines OJ, Gloor B, Thakur A, Todd KE, Kwon R, Reber HA. Pancreaticoduodenectomy (PD): Changes in clinical management and their fiscal implications. Gastroenterology 1998, 114:A1392.

17. Lane JS, Todd KE, Rigberg DA, Gloor B, Kau AD, Ashley SW, McFadden DW, Reber HA, Chandler CF. Endothelin antagonism reduces the systemic inflammatory response in a murine model of intestinal ischemia-reperfusion. Gastroenterology 1998, 114:A1404.

18. Lewis MPN Gloor B, Todd KE, Lane JS, Reber HA. Ethanol causes in vitro release of endothelin from isolated rat pancreatic acini. Gastroenterology 1998, 114:A478.

19. Gloor B, Blinman TA, Rigberg DA, Todd KE, Lane JS, Hines JO, Reber HA. Hepatic contribution to circulating cytokine levels in severe acute pancreatitis in rats. Gastroenterology 1998, 114:A462.

20. Gloor B, Blinman TA, Rigberg DA, Todd KE, Lane JS, Hines JO, Reber HA. Kupffer cell blockade reduces hepatic and systemic cytokine levels and lung injury in hemorrhagic pancreatitis in rats. Gastroenterology 1998, 114:A462.

21. Maggard, Melinda, Lane, KE, O’Connell, Jessica, Ko, Clifford, Do racial disparities exist for receipt of reconstructive surgery for breast cancer? Poster presentation SCACS, January 2004

22. Maggard, Melinda, Lane, KE, O’Connell, Jessica, Ko, Clifford, Beyond the clinical trials: How prevalent are sentinel lymph node biopsies performed for breast cancer? Oral Presentation March 2004, New York, N.Y.

23. Esserman L, Lane KT, Ewing CA, Hwang ES. Innovations in Breast Cancer Care. Johns Hopkins Advanced Studies in Medicine 2005 Vol 5(6):294-305.

24. Hsiang D, Yamamoto M, Mehta R, Baick C, Lane K, Butler J; Predicting nodal status using dynamic contrast-enhanced magnetic resonance imaging in patients with locally advanced breast cancer undergoing neoadjuvant chemotherapy with and without sequential trastuzumab. Archives of Surgery. 2007 Sep;142(9):855-61

25. Yamamoto M, Mehta RS, Baick CH, Su MY, Lane KT, Butler JA, Hsiang DJ. The predictive value of sentinel lymph node biopsy in locally advanced breast cancer patients who have undergone neoadjuvant chemotherapy. Am Surg. 2007 Oct;73(10):977-80.

26. Datrice N, Narula N, Butler JA, Hsiang D, Baick C, Lane KT, Do Breast Columnar Cell with Atypia Need to be Excised? The American Surgeon 2007 Oct;73(10):984-986

27. Ashley Kempf, BS, Karen Lane, MD, Cheryl Magno, MPH, et. al., Regional Differences in the use of Sentinel Lymph Node Biopsy for Melanoma: A Potential Quality Measure. Am Surg. 2008 Oct;74(10):981-4.

28. Karen Lane, MD, Nicole Datrice, MD, Cheryl Magno, MPH, Edith Smith, NP, John Butler, MD, David Hsiang, MD, Sheldon Greenfield, MD, Lari Wenzel, PhD. Evaluating the Quality of Follow-up Care in Breast Cancer Survivors. SCACS 2009 January, 17 Santa Barbara, CA.

29. Lane K, Hyunh K, Smith E, Hsiang D, Butler J. Acceptance of chemoprevention by women at high risk for breast cancer. American Society of Breast Surgeons May 2010, Las Vegas, NV

30. Piper M, Mehta RS, Butler J, Hsiang D, Wirth G, Lane K. The use of neoadjuvant bevacizumab and postoperative complications in patients undergoing mastectomy with immediate reconstruction. SCACS January 2011, Santa Barbara, CA

31. Datrice N, Wirth G, Hsiang D, Butler J, Lane KT. Can Regional Tattoos Impact Sentinel Lymph Node Identification? SCACS January 2012, Santa Barbara
Book Chapters

1. Todd KE, Reber HA. Pancreatic neoplasms. Current Opinion in Gastroenterology, Owyang C (ed); Rapid Science Publ, Philadelphia 1996, 12:436-441.

2. Todd KE, Lane JS, Reber HA. Questions most commonly asked regarding pancreatic cancer. Problems in General Surgery. Traverso W (ed); Lippincott-Raven, Philadelphia 1997; 141:27-32.

3. Todd KE, Reber HA. Pancreatic neoplasms. Current Opinion in Gastroenterology; Owyang C (ed). Rapid Science Publ, Philadelphia 1997, 13:392-397.

4. Todd KE, Reber HA. Pancreaticoduodenectomy in the United States. Pancreaticoduodenectomy. Hanyu F, Takasaki K (eds); Springer-Verlag, New York 1997, 381-387.

5. Todd KE, Reber HA. Adenocarcinoma of the Pancreas. Textbook of Clinical Gastroenterology; Brandt LJ (ed); Current Medicine, Philadelphia 1998, 139:1201-1206.

6. Todd KE, Reber HA. Indications for surgery in chronic pancreatitis. Problems in General Surgery. Prinz R, Deziel D (eds); Lippincott – Raven Publ, Philadelphia 1998, 15(1):48-53.

7. Gloor B, Hines OJ, Blinman TA, Rigberg DA, Todd KE, Lane JS, Reber HA. Role of Kupffer Cells in Acute Pancreatitis. Falk Symposium 113, Andus T, Rogler G, Schlottmann K, Frick E (eds); Kluwer Academic Publ, Boston 1999, 365-371.

8. Todd KE, Gloor B, Reber HA. Pancreatic adenocarcinoma. Textbook of Gastroenterology, Yamada T, et al (eds); Lippincott-Raven Publ, Philadelphia 1999,Volume 2: 2178-2193.

9. Todd KE and Chang H. Breast cancer risk factors and prevention. Cancer Prevention and Early Diagnosis in Women, Manetta A (ed); Elsevier Sci, Philadelphia 2001, 48-68.

10. Reber HA, Todd KE. Surgical management of cancer of the pancreas. Surgical Oncology: Multidisciplinary approach to difficult problems. Silberman AW, Silberman H (eds); Oxford Univ Press, New York 2002, 556-569.

11. Chalfoun C, Lane KT. Oncologic considerations for breast reconstruction. Aesthetic and Reconstructive Surgery of the Breast. Hall-Findlay EJ, Evans GRD (eds); Saunders Elsevier, 2010, 11-17.
Invited Articles, Critiques, Commentaries, Introductions

1. Lane KT, Esserman LJ. Sentinel lymph node dissection in early stage breast cancer: Current standards, controversies, and future considerations. Oncology Exchange 2004, 3(3):6-13.

2. Esserman L, Lane KT, Ewing CA, Hwang ES. Innovations in breast cancer care. Adv Stud Med 2005, 5(6):228-240.

3. Lane KT. Invited critique on: Litvak DA, Arora R. Treatment of Elderly Breast Cancer Patients in a Community Hospital Setting. Archives of Surgery Vol 141, October 2006

4. Lane KT. Improving quality of care for breast cancer survivors. Breast Diseases: A Yearbook Quarterly; Vol 17, No 4, 2007

5. Lane, KT; Clinical Challenges in Breast Disease. Seminars In Breast Disease: Diagnostic Imaging, Medical Oncology, Pathology, Radiation Oncology, Surgery; September 2007

6. Kempf A, Lane KT. Unusual Breast Lesions. Seminars in Breast Disease; 10:110-114; September 2007

7. Lane KT, Butler JA. Commentary on: Silberman H. Surgical Options for Stage I and II Breast Cancer (In Press Sept 2009)
Professional Societies
Alpha Omega Alpha Medical Honor Society
Association of Women Surgeons
Longmire Surgical Society
Fellow, American College of Surgeons
Society of Surgical Oncology
American Society of Breast Diseases
American Society of Breast Surgeons
National Association of Women Business Owners
Southern California Chapter: American College of Surgeon
National Consortium of Breast Centers
Other Experience
Clinical Instructor
University of California, Los Angeles, Division of Surgical Oncology 2000—2002
Assistant Professor in Residence
University of California, San Francisco School of Medicine 2002—2005
Last updated
01/06/2023